메뉴 건너뛰기




Volumn 3, Issue 5, 2012, Pages

LEAPS therapeutic vaccines as antigen specific suppressors of inflammation in infectious and autoimmune diseases

Author keywords

Antiviral vaccines; Autoimmunity; Cytokines; Dendritic cell; Immune response; Mode of action; Peptide; T cells; Vaccines

Indexed keywords


EID: 84879644138     PISSN: None     EISSN: 21577560     Source Type: Journal    
DOI: 10.4172/2157-7560.1000149     Document Type: Article
Times cited : (7)

References (65)
  • 1
    • 17444374626 scopus 로고    scopus 로고
    • Immune peptide enhancement of peptide based vaccines
    • Rosenthal KS (2005) Immune peptide enhancement of peptide based vaccines. Front Biosci 10: 478-482.
    • (2005) Front Biosci , vol.10 , pp. 478-482
    • Rosenthal, K.S.1
  • 2
    • 0029759944 scopus 로고    scopus 로고
    • A new approach to T-cell activation: Natural and synthetic conjugates capable of activating T cells. Vaccine research
    • Zimmerman D, Bergmann K, Rosenthal K and Elliott D (1996) A new approach to T-cell activation: natural and synthetic conjugates capable of activating T cells. Vaccine research. Liebert 5: 91-102.
    • (1996) Liebert , vol.5 , pp. 91-102
    • Zimmerman, D.1    Bergmann, K.2    Rosenthal, K.3    Elliott, D.4
  • 3
    • 0029784256 scopus 로고    scopus 로고
    • Immunization with peptide heterconjugates primes a t helper cell type 1-associated antibody (IgG2a) response that recognizes the native epitope on the 38-kDA protein of Mycobacterium tuberculosis. Vaccine research
    • Zimmerman DH, Morris S, Rouse D, Worthington K, Elliott D, et al. (1996) Immunization with peptide heterconjugates primes a t helper cell type 1-associated antibody (IgG2a) response that recognizes the native epitope on the 38-kDA protein of Mycobacterium tuberculosis. Vaccine research. Liebert 5: 103-118.
    • (1996) Liebert , vol.5 , pp. 103-118
    • Zimmerman, D.H.1    Morris, S.2    Rouse, D.3    Worthington, K.4    Elliott, D.5
  • 5
    • 77955052320 scopus 로고    scopus 로고
    • J-LEAPS vaccines initiate murine Th1 responses by activating dendritic cells
    • Taylor PR, Koski GK, Paustian CC, Bailey E, Cohen PA, et al. (2010) J-LEAPS vaccines initiate murine Th1 responses by activating dendritic cells. Vaccine 28: 5533-5542.
    • (2010) Vaccine , vol.28 , pp. 5533-5542
    • Taylor, P.R.1    Koski, G.K.2    Paustian, C.C.3    Bailey, E.4    Cohen, P.A.5
  • 6
    • 0346186985 scopus 로고    scopus 로고
    • A L.E.A.P.S. heteroconjugate vaccine containing a T cell epitope from HSV-1 glycoprotein D elicits Th1 responses and protection
    • Goel N, Rong Q, Zimmerman D, Rosenthal KS (2003) A L.E.A.P.S. heteroconjugate vaccine containing a T cell epitope from HSV-1 glycoprotein D elicits Th1 responses and protection. Vaccine 21: 4410-4420.
    • (2003) Vaccine , vol.21 , pp. 4410-4420
    • Goel, N.1    Rong, Q.2    Zimmerman, D.3    Rosenthal, K.S.4
  • 7
    • 32844465107 scopus 로고    scopus 로고
    • Ligand Epitope Antigen Presentation system vaccines against herpes simplex virus
    • Goel N, Zimmerman DH and Rosenthal KS (2005) Ligand Epitope Antigen Presentation system vaccines against herpes simplex virus. Frontiers in Bioscience 10: 966-974.
    • (2005) Frontiers in Bioscience , vol.10 , pp. 966-974
    • Goel, N.1    Zimmerman, D.H.2    Rosenthal, K.S.3
  • 9
    • 77949485280 scopus 로고    scopus 로고
    • CEL-2000: A therapeutic vaccine for rheumatoid arthritis arrests disease development and alters serum cytokine/chemokine patterns in the bovine collagen type II induced arthritis in the DBA mouse model
    • Zimmerman DH, Taylor P, Bendele A, Carambula R, Duzant Y, et al. (2010) CEL-2000: A therapeutic vaccine for rheumatoid arthritis arrests disease development and alters serum cytokine/chemokine patterns in the bovine collagen type II induced arthritis in the DBA mouse model. International immunopharmacology 10: 412-421.
    • (2010) International immunopharmacology , vol.10 , pp. 412-421
    • Zimmerman, D.H.1    Taylor, P.2    Bendele, A.3    Carambula, R.4    Duzant, Y.5
  • 10
    • 41149180875 scopus 로고    scopus 로고
    • L.E.A.P.S. heteroconjugate is able to prevent and treat experimental autoimmune myocarditis by altering trafficking of autoaggressive cells to the heart
    • Cihakova D, Barin JG, Baldeviano GC, Kimura M, Talor MV, et al. (2008) L.E.A.P.S. heteroconjugate is able to prevent and treat experimental autoimmune myocarditis by altering trafficking of autoaggressive cells to the heart. Int Immunopharmacol 8: 624-633.
    • (2008) Int Immunopharmacol , vol.8 , pp. 624-633
    • Cihakova, D.1    Barin, J.G.2    Baldeviano, G.C.3    Kimura, M.4    Talor, M.V.5
  • 12
    • 0021111991 scopus 로고
    • Arginine 45 is a major part of the antigenic determinant of human beta 2-microglobulin recognized by mouse monoclonal antibody BBM.1
    • Parham P, Androlewicz MJ, Holmes NJ, Rothenberg BE (1983) Arginine 45 is a major part of the antigenic determinant of human beta 2-microglobulin recognized by mouse monoclonal antibody BBM.1. J Biol Chem 258: 6179-6186.
    • (1983) J Biol Chem , vol.258 , pp. 6179-6186
    • Parham, P.1    Androlewicz, M.J.2    Holmes, N.J.3    Rothenberg, B.E.4
  • 13
    • 0026563077 scopus 로고
    • MHC class II interaction with CD4 mediated by a region analogous to the MHC class I binding site for CD8
    • Konig R, Huang LY, Germain RN (1992) MHC class II interaction with CD4 mediated by a region analogous to the MHC class I binding site for CD8. Nature 356: 796-798.
    • (1992) Nature , vol.356 , pp. 796-798
    • Konig, R.1    Huang, L.Y.2    Germain, R.N.3
  • 14
    • 0026600191 scopus 로고
    • Identification of a CD4 binding site on the beta 2 domain of HLA-DR molecules
    • Cammarota G, Scheirle A, Takacs B, Doran DM, Knorr R, et al. (1992) Identification of a CD4 binding site on the beta 2 domain of HLA-DR molecules. Nature 356: 799-801.
    • (1992) Nature , vol.356 , pp. 799-801
    • Cammarota, G.1    Scheirle, A.2    Takacs, B.3    Doran, D.M.4    Knorr, R.5
  • 15
    • 0037157270 scopus 로고    scopus 로고
    • Flt3 ligand and conjugation to IL-1beta peptide as adjuvants for a type 1, T-cell response to an HIV p17 gag vaccine
    • Pisarev VM, Parajuli P, Mosley RL, Chavez J, Zimmerman D, et al. (2002) Flt3 ligand and conjugation to IL-1beta peptide as adjuvants for a type 1, T-cell response to an HIV p17 gag vaccine. Vaccine 20: 2358-2368.
    • (2002) Vaccine , vol.20 , pp. 2358-2368
    • Pisarev, V.M.1    Parajuli, P.2    Mosley, R.L.3    Chavez, J.4    Zimmerman, D.5
  • 16
    • 84857201851 scopus 로고    scopus 로고
    • Ex vivo stimulation assay for T-cell responses for tuberculosis using LEAPS-peptide heteroconjugates
    • Walton C, Jube S, Schorlemmer A, Patek P, Zimmerman D, et al. (2010) Ex vivo stimulation assay for T-cell responses for tuberculosis using LEAPS-peptide heteroconjugates. Curr Trends in Microbiol 6: 1-12.
    • (2010) Curr Trends in Microbiol , vol.6 , pp. 1-12
    • Walton, C.1    Jube, S.2    Schorlemmer, A.3    Patek, P.4    Zimmerman, D.5
  • 17
    • 0035860621 scopus 로고    scopus 로고
    • Induction of cross clade reactive specific antibodies in mice by conjugates of HGP-30 (peptide analog of HIV-1(SF2) p17) and peptide segments of human beta-2-microglobulin or MHC II beta chain
    • Zimmerman DH, Lloyd JP, Heisey D, Winship MD, Siwek M, et al. (2001) Induction of cross clade reactive specific antibodies in mice by conjugates of HGP-30 (peptide analog of HIV-1(SF2) p17) and peptide segments of human beta-2-microglobulin or MHC II beta chain. Vaccine 19: 4750-4759.
    • (2001) Vaccine , vol.19 , pp. 4750-4759
    • Zimmerman, D.H.1    Lloyd, J.P.2    Heisey, D.3    Winship, M.D.4    Siwek, M.5
  • 18
    • 33646936414 scopus 로고    scopus 로고
    • The L.E.A.P.S. approach to vaccine development
    • Zimmerman DH, Rosenthal KS (2005) The L.E.A.P.S. approach to vaccine development. Front Biosci 10: 790-798.
    • (2005) Front Biosci , vol.10 , pp. 790-798
    • Zimmerman, D.H.1    Rosenthal, K.S.2
  • 19
    • 0033547872 scopus 로고    scopus 로고
    • Immunization with a LEAPS heteroconjugate containing a CTL epitope and a peptide from beta-2-microglobulin elicits a protective and DTH response to herpes simplex virus type 1
    • Rosenthal KS, Mao H, Horne WI, Wright C, Zimmerman D (1999) Immunization with a LEAPS heteroconjugate containing a CTL epitope and a peptide from beta-2-microglobulin elicits a protective and DTH response to herpes simplex virus type 1. Vaccine 17: 535-542.
    • (1999) Vaccine , vol.17 , pp. 535-542
    • Rosenthal, K.S.1    Mao, H.2    Horne, W.I.3    Wright, C.4    Zimmerman, D.5
  • 21
    • 43449113883 scopus 로고    scopus 로고
    • Interleukin-13 protects against experimental autoimmune myocarditis by regulating macrophage differentiation
    • Cihakova D, Barin JG, Afanasyeva M, Kimura M, Fairweather D, et al. (2008) Interleukin-13 protects against experimental autoimmune myocarditis by regulating macrophage differentiation. Am J Pathol 172: 1195-1208.
    • (2008) Am J Pathol , vol.172 , pp. 1195-1208
    • Cihakova, D.1    Barin, J.G.2    Afanasyeva, M.3    Kimura, M.4    Fairweather, D.5
  • 22
    • 0028871371 scopus 로고
    • Myocarditis-inducing epitope of myosin binds constitutively and stably to I-Ak on antigen-presenting cells in the heart
    • Donermeyer DL, Beisel KW, Allen PM, Smith SC (1995) Myocarditis-inducing epitope of myosin binds constitutively and stably to I-Ak on antigen-presenting cells in the heart. J Exp Med 182: 1291-1300.
    • (1995) J Exp Med , vol.182 , pp. 1291-1300
    • Donermeyer, D.L.1    Beisel, K.W.2    Allen, P.M.3    Smith, S.C.4
  • 23
    • 33644875922 scopus 로고    scopus 로고
    • Critical role for monocyte chemoattractant protein-1 and macrophage inflammatory protein-1alpha in induction of experimental autoimmune myocarditis and effective anti-monocyte chemoattractant protein-1 gene therapy
    • Göser S, Ottl R, Brodner A, Dengler TJ, Torzewski J, et al. (2005) Critical role for monocyte chemoattractant protein-1 and macrophage inflammatory protein-1alpha in induction of experimental autoimmune myocarditis and effective anti-monocyte chemoattractant protein-1 gene therapy. Circulation 112: 3400-3407.
    • (2005) Circulation , vol.112 , pp. 3400-3407
    • Göser, S.1    Ottl, R.2    Brodner, A.3    Dengler, T.J.4    Torzewski, J.5
  • 24
    • 2542498041 scopus 로고    scopus 로고
    • Severe anaphylactic reactions to glutamic acid decarboxylase (GAD) self peptides in NOD mice that spontaneously develop autoimmune type 1 diabetes mellitus
    • Pedotti R, Sanna M, Tsai M, DeVoss J, Steinman L, et al. (2003) Severe anaphylactic reactions to glutamic acid decarboxylase (GAD) self peptides in NOD mice that spontaneously develop autoimmune type 1 diabetes mellitus. BMC Immunol 4: 2.
    • (2003) BMC Immunol , vol.4 , pp. 2
    • Pedotti, R.1    Sanna, M.2    Tsai, M.3    DeVoss, J.4    Steinman, L.5
  • 25
    • 0037452593 scopus 로고    scopus 로고
    • Multiple elements of the allergic arm of the immune response modulate autoimmune demyelination
    • Pedotti R, DeVoss JJ, Youssef S, Mitchell D, Wedemeyer J, et al. (2003) Multiple elements of the allergic arm of the immune response modulate autoimmune demyelination. Proc Natl Acad Sci U S A 100: 1867-1872.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 1867-1872
    • Pedotti, R.1    DeVoss, J.J.2    Youssef, S.3    Mitchell, D.4    Wedemeyer, J.5
  • 26
    • 37549045964 scopus 로고    scopus 로고
    • Peptide-based immunotherapy of experimental autoimmune encephalomyelitis without anaphylaxis
    • Leech MD, Chung CY, Culshaw A, Anderton SM (2007) Peptide-based immunotherapy of experimental autoimmune encephalomyelitis without anaphylaxis. Eur J Immunol 37: 3576-3581.
    • (2007) Eur J Immunol , vol.37 , pp. 3576-3581
    • Leech, M.D.1    Chung, C.Y.2    Culshaw, A.3    Anderton, S.M.4
  • 28
    • 3242762702 scopus 로고    scopus 로고
    • Preventing peptide-induced anaphylaxis: Addition of C-terminal amino acids to produce a neutral isoelectric point
    • Liu E, Moriyama H, Abiru N, Paronen J, Devendra D, et al. (2004) Preventing peptide-induced anaphylaxis: addition of C-terminal amino acids to produce a neutral isoelectric point. J Allergy Clin Immunol 114: 607-613.
    • (2004) J Allergy Clin Immunol , vol.114 , pp. 607-613
    • Liu, E.1    Moriyama, H.2    Abiru, N.3    Paronen, J.4    Devendra, D.5
  • 29
    • 0036790542 scopus 로고    scopus 로고
    • Anti-peptide autoantibodies and fatal anaphylaxis in NOD mice in response to insulin self-peptides B:9-23 and B:13-23
    • Liu E, Moriyama H, Abiru N, Miao D, Yu L, et al. (2002) Anti-peptide autoantibodies and fatal anaphylaxis in NOD mice in response to insulin self-peptides B:9-23 and B:13-23. J Clin Invest 110: 1021-1027.
    • (2002) J Clin Invest , vol.110 , pp. 1021-1027
    • Liu, E.1    Moriyama, H.2    Abiru, N.3    Miao, D.4    Yu, L.5
  • 30
    • 0026750345 scopus 로고
    • Characterization of a tolerogenic T cell epitope of type II collagen and its relevance to collagen-induced arthritis
    • Myers LK, Terato K, Seyer JM, Stuart JM, Kang AH (1992) Characterization of a tolerogenic T cell epitope of type II collagen and its relevance to collagen-induced arthritis. J Immunol 149: 1439-1443.
    • (1992) J Immunol , vol.149 , pp. 1439-1443
    • Myers, L.K.1    Terato, K.2    Seyer, J.M.3    Stuart, J.M.4    Kang, A.H.5
  • 31
    • 2442452758 scopus 로고    scopus 로고
    • Vaccination with an immunodominant peptide of bovine type II collagen induces an anti-TCR response, and modulates the onset and severity of collagen-induced arthritis
    • Honda A, Ametani A, Matsumoto T, Iwaya A, Kano H, et al. (2004) Vaccination with an immunodominant peptide of bovine type II collagen induces an anti-TCR response, and modulates the onset and severity of collagen-induced arthritis. Int Immunol 16: 737-745.
    • (2004) Int Immunol , vol.16 , pp. 737-745
    • Honda, A.1    Ametani, A.2    Matsumoto, T.3    Iwaya, A.4    Kano, H.5
  • 32
    • 25444464603 scopus 로고    scopus 로고
    • Animal models of rheumatoid arthritis and their relevance to human disease
    • Kannan K, Ortmann RA, Kimpel D (2005) Animal models of rheumatoid arthritis and their relevance to human disease. Pathophysiology 12: 167-181.
    • (2005) Pathophysiology , vol.12 , pp. 167-181
    • Kannan, K.1    Ortmann, R.A.2    Kimpel, D.3
  • 33
    • 23444454526 scopus 로고    scopus 로고
    • Rodent models of rheumatoid arthritis
    • Brand DD (2005) Rodent models of rheumatoid arthritis. Comp Med 55: 114-122.
    • (2005) Comp Med , vol.55 , pp. 114-122
    • Brand, D.D.1
  • 34
    • 77955363222 scopus 로고    scopus 로고
    • Evaluation of therapeutic targets in animal models of arthritis: How does it relate to rheumatoid arthritis?
    • Bevaart L, Vervoordeldonk MJ, Tak PP (2010) Evaluation of therapeutic targets in animal models of arthritis: how does it relate to rheumatoid arthritis? Arthritis Rheum 62: 2192-2205.
    • (2010) Arthritis Rheum , vol.62 , pp. 2192-2205
    • Bevaart, L.1    Vervoordeldonk, M.J.2    Tak, P.P.3
  • 35
    • 0034104762 scopus 로고    scopus 로고
    • Herpes simplex virus infections. New treatment approaches make early diagnosis even more important
    • Nadelman CM, Newcomer VD (2000) Herpes simplex virus infections. New treatment approaches make early diagnosis even more important. Postgrad Med 107: 189-195, 199-200.
    • (2000) Postgrad Med , vol.107
    • Nadelman, C.M.1    Newcomer, V.D.2
  • 37
    • 0019202903 scopus 로고
    • Reaction patterns of herpes simplex virus type 1 and type 2 proteins with sera of patients with uterine cervical carcinoma and matched controls
    • Gilman SC, Docherty JJ, Clarke A, Rawls WE (1980) Reaction patterns of herpes simplex virus type 1 and type 2 proteins with sera of patients with uterine cervical carcinoma and matched controls. Cancer Res 40: 4640-4647.
    • (1980) Cancer Res , vol.40 , pp. 4640-4647
    • Gilman, S.C.1    Docherty, J.J.2    Clarke, A.3    Rawls, W.E.4
  • 38
    • 0021326802 scopus 로고
    • Incidence of herpes simplex virus types 1 and 2 in penile lesions of college men
    • Docherty JJ, Lohse MA, Dellaria MF, Naugle FP, Mason CW, et al. (1984) Incidence of herpes simplex virus types 1 and 2 in penile lesions of college men. J Med Virol 13: 163-170.
    • (1984) J Med Virol , vol.13 , pp. 163-170
    • Docherty, J.J.1    Lohse, M.A.2    Dellaria, M.F.3    Naugle, F.P.4    Mason, C.W.5
  • 40
    • 0021963096 scopus 로고
    • Identification and typing of herpes simplex virus types 1 and 2 by monoclonal antibodies, sensitivity to the drug (E)-5-(2-bromovinyl)-2'-deoxyuridine, and restriction endonuclease analysis of viral DNA
    • Zimmerman DH, Mundon FK, Croson SE, Henchal LS, Docherty JJ, et al. (1985) Identification and typing of herpes simplex virus types 1 and 2 by monoclonal antibodies, sensitivity to the drug (E)-5-(2-bromovinyl)-2'-deoxyuridine, and restriction endonuclease analysis of viral DNA. J Med Virol 15: 215-222.
    • (1985) J Med Virol , vol.15 , pp. 215-222
    • Zimmerman, D.H.1    Mundon, F.K.2    Croson, S.E.3    Henchal, L.S.4    Docherty, J.J.5
  • 41
    • 23744442476 scopus 로고    scopus 로고
    • Immunomodulatory effects of HSV-2 infection on immature macaque dendritic cells modify innate and adaptive responses
    • Peretti S, Shaw A, Blanchard J, Bohm R, Morrow G, et al. (2005) Immunomodulatory effects of HSV-2 infection on immature macaque dendritic cells modify innate and adaptive responses. Blood 106: 1305-1313.
    • (2005) Blood , vol.106 , pp. 1305-1313
    • Peretti, S.1    Shaw, A.2    Blanchard, J.3    Bohm, R.4    Morrow, G.5
  • 42
    • 0029609713 scopus 로고
    • Immunomodulatory effects of HSV2 glycoprotein D in HSV1 infected mice: Implications for immunotherapy of recurrent HSV infection
    • York LJ, Giorgio DP, Mishkin EM (1995) Immunomodulatory effects of HSV2 glycoprotein D in HSV1 infected mice: implications for immunotherapy of recurrent HSV infection. Vaccine 13: 1706-1712.
    • (1995) Vaccine , vol.13 , pp. 1706-1712
    • York, L.J.1    Giorgio, D.P.2    Mishkin, E.M.3
  • 43
    • 0028842912 scopus 로고
    • Roles of different T-cell subsets in control of herpes simplex virus infection determined by using T-cell-deficient mouse-models
    • Manickan E and Rouse BT (1995) Roles of different T-cell subsets in control of herpes simplex virus infection determined by using T-cell-deficient mouse-models. Journal of virology 69: 8178-8179.
    • (1995) Journal of virology , vol.69 , pp. 8178-8179
    • Manickan, E.1    Rouse, B.T.2
  • 44
  • 45
    • 0026752898 scopus 로고
    • The role of T cell immunity in control of herpes simplex virus
    • Schmid DS, Rouse BT (1992) The role of T cell immunity in control of herpes simplex virus. Curr Top Microbiol Immunol 179: 57-74.
    • (1992) Curr Top Microbiol Immunol , vol.179 , pp. 57-74
    • Schmid, D.S.1    Rouse, B.T.2
  • 46
    • 0035983126 scopus 로고    scopus 로고
    • The ability of an HSV strain to initiate zosteriform spread correlates with its neuroinvasive disease potential
    • Goel N, Mao H, Rong Q, Docherty JJ, Zimmerman D, et al. (2002) The ability of an HSV strain to initiate zosteriform spread correlates with its neuroinvasive disease potential. Arch Virol 147: 763-773.
    • (2002) Arch Virol , vol.147 , pp. 763-773
    • Goel, N.1    Mao, H.2    Rong, Q.3    Docherty, J.J.4    Zimmerman, D.5
  • 47
    • 0345358584 scopus 로고    scopus 로고
    • The IL-12 family of heterodimeric cytokines: New players in the regulation of T cell responses
    • Trinchieri G, Pflanz S, Kastelein RA (2003) The IL-12 family of heterodimeric cytokines: new players in the regulation of T cell responses. Immunity 19: 641-644.
    • (2003) Immunity , vol.19 , pp. 641-644
    • Trinchieri, G.1    Pflanz, S.2    Kastelein, R.A.3
  • 48
    • 84863990904 scopus 로고    scopus 로고
    • WHO, World Health Organization
    • WHO (2003) Factsheet 211: influenza. World Health Organization.
    • (2003) Factsheet 211: Influenza
  • 49
    • 84859596107 scopus 로고    scopus 로고
    • WHO, World Health Organization
    • WHO (2008) Global influenza surveillance. World Health Organization.
    • (2008) Global influenza surveillance
  • 50
    • 34548611066 scopus 로고    scopus 로고
    • Influenza vaccine: The challenge of antigenic drift
    • Carrat F, Flahault A (2007) Influenza vaccine: the challenge of antigenic drift. Vaccine 25: 6852-6862.
    • (2007) Vaccine , vol.25 , pp. 6852-6862
    • Carrat, F.1    Flahault, A.2
  • 51
    • 0033561792 scopus 로고    scopus 로고
    • Covalent linkage to beta2-microglobulin enhances the MHC stability and antigenicity of suboptimal CTL epitopes
    • Uger RA, Chan SM, Barber BH (1999) Covalent linkage to beta2-microglobulin enhances the MHC stability and antigenicity of suboptimal CTL epitopes. J Immunol 162: 6024-6028.
    • (1999) J Immunol , vol.162 , pp. 6024-6028
    • Uger, R.A.1    Chan, S.M.2    Barber, B.H.3
  • 52
    • 0036229655 scopus 로고    scopus 로고
    • Induction of long-term memory CD8(+) T cells for recall of viral clearing responses against influenza virus
    • Deliyannis G, Jackson DC, Ede NJ, Zeng W, Hourdakis I, et al. (2002) Induction of long-term memory CD8(+) T cells for recall of viral clearing responses against influenza virus. J Virol 76: 4212-4221.
    • (2002) J Virol , vol.76 , pp. 4212-4221
    • Deliyannis, G.1    Jackson, D.C.2    Ede, N.J.3    Zeng, W.4    Hourdakis, I.5
  • 53
    • 0002866386 scopus 로고    scopus 로고
    • Dissecting the multifactorial causes of immunodominance in class I-restricted T cell responses to viruses
    • Chen W, Anton LC, Bennink JR, Yewdell JW (2000) Dissecting the multifactorial causes of immunodominance in class I-restricted T cell responses to viruses. Immunity 12: 83-93.
    • (2000) Immunity , vol.12 , pp. 83-93
    • Chen, W.1    Anton, L.C.2    Bennink, J.R.3    Yewdell, J.W.4
  • 54
    • 3843069907 scopus 로고    scopus 로고
    • Preclinical study of influenza virus A M2 peptide conjugate vaccines in mice, ferrets, and rhesus monkeys
    • Fan J, Liang X, Horton MS, Perry HC, Citron MP, et al. (2004) Preclinical study of influenza virus A M2 peptide conjugate vaccines in mice, ferrets, and rhesus monkeys. Vaccine 22: 2993-3003.
    • (2004) Vaccine , vol.22 , pp. 2993-3003
    • Fan, J.1    Liang, X.2    Horton, M.S.3    Perry, H.C.4    Citron, M.P.5
  • 55
    • 0038402706 scopus 로고    scopus 로고
    • Induction of influenza type A virus-specific resistance by immunization of mice with a synthetic multiple antigenic peptide vaccine that contains ectodomains of matrix protein 2
    • Mozdzanowska K, Feng J, Eid M, Kragol G, Cudic M, et al. (2003) Induction of influenza type A virus-specific resistance by immunization of mice with a synthetic multiple antigenic peptide vaccine that contains ectodomains of matrix protein 2. Vaccine 21: 2616-2626.
    • (2003) Vaccine , vol.21 , pp. 2616-2626
    • Mozdzanowska, K.1    Feng, J.2    Eid, M.3    Kragol, G.4    Cudic, M.5
  • 56
  • 57
    • 33845618007 scopus 로고    scopus 로고
    • Influenza A virus infection engenders a poor antibody response against the ectodomain of matrix protein 2
    • Feng J, Zhang M, Mozdzanowska K, Zharikova D, Hoff H, et al. (2006) Influenza A virus infection engenders a poor antibody response against the ectodomain of matrix protein 2. Virology Journal 3: 102.
    • (2006) Virology Journal , vol.3 , pp. 102
    • Feng, J.1    Zhang, M.2    Mozdzanowska, K.3    Zharikova, D.4    Hoff, H.5
  • 58
    • 33744810606 scopus 로고    scopus 로고
    • Fine specificity and sequence of antibodies directed against the ectodomain of matrix protein 2 of influenza A virus
    • Zhang M, Zharikova D, Mozdzanowska K, Otvos L and Gerhard W (2006) Fine specificity and sequence of antibodies directed against the ectodomain of matrix protein 2 of influenza A virus. Molecular immunology 43: 2195-2206.
    • (2006) Molecular immunology , vol.43 , pp. 2195-2206
    • Zhang, M.1    Zharikova, D.2    Mozdzanowska, K.3    Otvos, L.4    Gerhard, W.5
  • 59
    • 18744377200 scopus 로고    scopus 로고
    • Influenza type A virus escape mutants emerge in vivo in the presence of antibodies to the ectodomain of matrix protein 2
    • Zharikova D, Mozdzanowska K, Feng J, Zhang M, Gerhard W (2005) Influenza type A virus escape mutants emerge in vivo in the presence of antibodies to the ectodomain of matrix protein 2. J Virol 79: 6644-6654.
    • (2005) J Virol , vol.79 , pp. 6644-6654
    • Zharikova, D.1    Mozdzanowska, K.2    Feng, J.3    Zhang, M.4    Gerhard, W.5
  • 60
    • 62749124125 scopus 로고    scopus 로고
    • Monoclonal antibodies against the fusion peptide of hemagglutinin protect mice from lethal influenza A virus H5N1 infection
    • Prabhu N, Prabakaran M, Ho HT, Velumani S, Qiang J, et al. (2009) Monoclonal antibodies against the fusion peptide of hemagglutinin protect mice from lethal influenza A virus H5N1 infection. J Virol 83: 2553-2562.
    • (2009) J Virol , vol.83 , pp. 2553-2562
    • Prabhu, N.1    Prabakaran, M.2    Ho, H.T.3    Velumani, S.4    Qiang, J.5
  • 62
    • 79955042531 scopus 로고    scopus 로고
    • Highly conserved influenza A sequences as T cell epitopes-based vaccine targets to address the viral variability
    • Tan PT, Khan AM, August JT (2011) Highly conserved influenza A sequences as T cell epitopes-based vaccine targets to address the viral variability. Hum Vaccin 7: 402-409.
    • (2011) Hum Vaccin , vol.7 , pp. 402-409
    • Tan, P.T.1    Khan, A.M.2    August, J.T.3
  • 63
    • 62049083943 scopus 로고    scopus 로고
    • Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses
    • Sui J, Hwang WC, Perez S, Wei G and Aird D, et al. (2009) Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses. Nature structural & molecular biology 16: 265-273.
    • (2009) Nature structural & molecular biology , vol.16 , pp. 265-273
    • Sui, J.1    Hwang, W.C.2    Perez, S.3    Wei, G.4    Aird, D.5
  • 64
    • 84861963299 scopus 로고    scopus 로고
    • Synthetic Influenza vaccine (FLU-v) stimulates cell mediated immunity in a double-blind, randomised, placebo-controlled Phase I trial
    • Pleguezuelos O, Robinson S, Stoloff GA, Caparros-Wanderley W (2012) Synthetic Influenza vaccine (FLU-v) stimulates cell mediated immunity in a double-blind, randomised, placebo-controlled Phase I trial. Vaccine 30: 4655-4660.
    • (2012) Vaccine , vol.30 , pp. 4655-4660
    • Pleguezuelos, O.1    Robinson, S.2    Stoloff, G.A.3    Caparros-Wanderley, W.4
  • 65
    • 71649110874 scopus 로고    scopus 로고
    • Immunomodulation by semi-mature dendritic cells: A novel role of Toll-like receptors and interleukin-6
    • Frick JS, Grunebach F, Autenrieth IB (2010) Immunomodulation by semi-mature dendritic cells: a novel role of Toll-like receptors and interleukin-6. Int J Med Microbiol 300: 19-24.
    • (2010) Int J Med Microbiol , vol.300 , pp. 19-24
    • Frick, J.S.1    Grunebach, F.2    Autenrieth, I.B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.