L.E.A.P.S. heteroconjugate is able to prevent and treat experimental autoimmune myocarditis by altering trafficking of autoaggressive cells to the heart

International Immunopharmacology

Volumn 8, Issue 5, 2008, Pages 624-633

  Cihakova, Daniela ^a   Barin, Jobert G ^a   Baldeviano, G Christian ^b   Kimura, Miho ^a   Talor, Monica V ^a   Zimmerman, Daniel H ^c   Talor, Eyal ^c   Rose, Noel R ^a,b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^c CEL SCI Corporation   (United States)

Author keywords

Altered peptide ligand (APL); Antigen specific therapy; Autoimmunity; Experimental autoimmune myocarditis (EAM); Myocarditis

Indexed keywords

BETA 2 MICROGLOBULIN; CARDIAC MYOSIN; CD69 ANTIGEN; HERMES ANTIGEN; PEPTIDE DERIVATIVE;

ANAPHYLAXIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY PRODUCING CELL; ANTIBODY SPECIFICITY; ARTICLE; AUTOIMMUNE DISEASE; AUTOIMMUNE MYOCARDITIS; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL MIGRATION; CONTROLLED STUDY; DEATH; DENDRITIC CELL; DISEASE SEVERITY; FEMALE; IMMUNE RESPONSE; INCIDENCE; LIGAND EPITOPE ANTIGEN PRESENTATION SYSTEM; MEDICAL TECHNOLOGY; MOUSE; MYOCARDITIS; NONHUMAN; PRIORITY JOURNAL; PROPHYLAXIS; SPLEEN; TECHNOLOGY;

ANIMALS; ANTIGEN PRESENTATION; AUTOIMMUNE DISEASES; CELL PROLIFERATION; CHEMOKINE CCL3; CHEMOKINE CXCL10; CHEMOKINES; CLONAL ANERGY; CYTOKINES; DENDRITIC CELLS; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITOPES; FEMALE; HISTAMINE RELEASE; IMMUNOGLOBULIN J-CHAINS; LIGANDS; MICE; MICE, INBRED A; MYOCARDITIS; MYOCARDIUM; SPLEEN; TH1 CELLS; TH2 CELLS;

EID: 41149180875     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.intimp.2008.01.004     Document Type: Article

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