Selective agonists and antagonists of formylpeptide receptors: Duplex flow cytometry and mixture-based positional scanning libraries

Molecular Pharmacology

Volumn 84, Issue 3, 2013, Pages 314-324

  Pinilla, Clemencia ^a   Edwards, Bruce S ^b   Appel, Jon R ^a   Yates Gibbins, Tina ^a   Giulianotti, Marc A ^a   Medina Franco, Jose L ^a   Young, Susan M ^b   Santos, Radleigh G ^a   Sklar, Larry A ^b   Houghten, Richard A ^a  

^a TORREY PINES INSTITUTE FOR MOLECULAR STUDIES   (United States)

^b UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 PHENYL 1 (1 (3 PHENYL 1 (1 (3 PHENYLUREIDO)PROPAN 2 YL)UREIDO)HEXAN 2 YL) 1 (4 PHENYLBUTYL)UREA; 4 (2 ((1,19 BIPHENYL) 4 YL)ETHYL) 1 (1 (2 ((6 BUTYL 2,3 DIOXOPIPERAZIN 1 YL)METHYL)PYRROLIDIN1 YL)PENTAN 2 YL) 5 (4 HYDROXYBENZYL)PIPERAZINE 2,3 DIONE; 4 (2 ((1,19 BIPHENYL) 4 YL)ETHYL) 5 (4 HYDROXYBENZYL) 1 (1 (2 ((6 ISOPROPYL 2,3 DIOXOPIPERAZIN 1 YL)METHYL)PYRROLIDIN 1 YL)PENTAN 2 YL) PIPERAZINE 2,3 DIONE; 4 (2 ((1,19 BIPHENYL) 4 YL)ETHYL) 5 (4 HYDROXYBENZYL) 1 (1 (4 HYDROXYPHENYL) 3 (2 ((6 ISOPROPYL 2,3 DIOXOPIPERAZIN 1 YL)METHYL)PYRROLIDIN 1 YL)PROPAN 2 YL)PIPERAZINE 2,3 DIONE; 4 (CYCLOHEXYLMETHYL) 1 (1 (2 ((2,3 DIOXO 6 PROPYLPIPERAZIN 1 YL)METHYL)PYRROLIDIN YL) 3 (NAPHTHALEN 2 YL)PROPAN 2 YL) 5 (4 HYDROXYBENZYL)PIPERAZINE 2,3 DIONE; 4 (CYCLOHEXYLMETHYL) 5 (4 HYDROXYBENZYL) 1 (1 (2 ((6 ISOPROPYL 2,3DIOXOPIPERAZIN 1 YL)METHYL)PYRROLIDIN 1 YL) 3 (NAPHTHALEN 2 YL)PROPAN 2 YL)PIPERAZINE 2,3 DIONE; 4 (CYCLOHEXYLMETHYL) 5 (4 HYDROXYBENZYL) 1 (1 (4 HYDROXYPHENYL) 3 (2 ((6 ISOPROPYL 2,3 DIOXOPIPERAZIN 1 YL)METHYL)PYRROLIDIN 1 YL)PROPAN 2 YL)PIPERAZINE 2,3 DIONE; CALCIUM ION; FORMYLPEPTIDE RECEPTOR; FORMYLPEPTIDE RECEPTOR AGONIST; FORMYLPEPTIDE RECEPTOR ANTAGONIST; FORMYLPEPTIDE RECEPTOR LIKE 1; G PROTEIN COUPLED RECEPTOR; PIPERAZINE DERIVATIVE; PYRROLIDINE DERIVATIVE; UNCLASSIFIED DRUG; UREA DERIVATIVE;

ARTICLE; BINDING AFFINITY; CALCIUM CELL LEVEL; CHEMICAL STRUCTURE; COMBINATORIAL LIBRARY; COST EFFECTIVENESS ANALYSIS; DOSE RESPONSE; FLOW CYTOMETRY; FLUORESCENCE; GLIOMA; HIGH THROUGHPUT SCREENING; INFLAMMATION; LIGAND BINDING; MASS SPECTROMETRY; MEDICAL TECHNOLOGY; METASTASIS; MOLECULE; PEPTIDE LIBRARY; POSITIONAL SCANNING LIBRARY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RECEPTOR BINDING; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; STEM CELL; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

AMINO ACIDS; ANIMALS; CALCIUM; CELL LINE, TUMOR; DIKETOPIPERAZINES; DOSE-RESPONSE RELATIONSHIP, DRUG; FLOW CYTOMETRY; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; PEPTIDES; PEPTIDOMIMETICS; PYRROLIDINES; RATS; RECEPTORS, FORMYL PEPTIDE; SMALL MOLECULE LIBRARIES; STEREOISOMERISM;

EID: 84879592714     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.113.086595     Document Type: Article

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