A feedback loop in PPARγ-adenosine A2A receptor signaling inhibits inflammation and attenuates lung damages in a mouse model of LPS-induced acute lung injury

Cellular Signalling

Volumn 25, Issue 9, 2013, Pages 1913-1923

  He, Xie ^a   Hu, Jian Lin ^a   Li, Jun ^a   Zhao, Li ^a   Zhang, Yan ^a   Zeng, Yi Jun ^a   Dai, Shuang Shuang ^a   He, Feng Tian ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

A2AR; ALI; Inflammation; PPAR

Indexed keywords

ADENOSINE A2A RECEPTOR; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA;

ACUTE LUNG INJURY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEEDBACK SYSTEM; GAS EXCHANGE; INFLAMMATION; LIPOPOLYSACCHARIDE INDUCED ACUTE LUNG INJURY; LUNG FUNCTION; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; UPREGULATION;

ACUTE LUNG INJURY; ADENOSINE A2 RECEPTOR AGONISTS; ANIMALS; CELL LINE; CELLS, CULTURED; CYTOKINES; INFLAMMATION; LIPOPOLYSACCHARIDES; LUNG; MACROPHAGES; MICE; PPAR GAMMA; RECEPTOR, ADENOSINE A2A; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRANSCRIPTIONAL ACTIVATION; UP-REGULATION;

MURINAE;

EID: 84879534355     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2013.05.024     Document Type: Article

References (51)

1. Ware L.B., Matthay M.A. The New England Journal of Medicine 2000, 342:1334-1349.
2. Welbourn C.R., Young Y. British Journal of Surgery 1992, 79:998-1003.
3. Schwab J.M., Chiang N., Arita M., Serhan C.N. Nature 2007, 447:869-874.
4. Levy B.D., De Sanctis G.T., Devchand P.R., Kim E., Ackerman K., Schmidt B.A., Szczeklik W., Drazen J.M., Serhan C.N. Nature Medicine 2002, 8:1018-1023.
5. Serhan C.N., Krishnamoorthy S., Recchiuti A., Chiang N. Current Topics in Medicinal Chemistry 2011, 11:629-647.
6. Ohta A., Sitkovsky M. Nature 2001, 414:916-920.
7. Reutershan J., Cagnina R.E., Chang D., Linden J., Ley K. Journal of Immunology 2007, 179:1254-1263.
8. Sharma A.K., Linden J., Kron I.L., Laubach V.E. Respiratory Research 2009, 10:58.
9. Eckle T., Koeppen M., Eltzschig H.K. Physiology (Bethesda, Md.) 2009, 24:298-306.
10. Wang A.C., Dai X., Luu B., Conrad D.J. American Journal of Respiratory Cell and Molecular Biology 2001, 24:688-693.
11. Ameshima S., Golpon H., Cool C.D., Chan D., Vandivier R.W., Gardai S.J., Wick M., Nemenoff R.A., Geraci M.W., Voelkel N.F. Circulation Research 2003, 92:1162-1169.
12. Patel H.J., Belvisi M.G., Bishop-Bailey D., Yacoub M.H., Mitchell J.A. Journal of Immunology 2003, 170:2663-2669.
13. Reddy R.C., Keshamouni V.G., Jaigirdar S.H., Zeng X., Leff T., Thannickal V.J., Standiford T.J. American Journal of Physiology. Lung Cellular and Molecular Physiology 2004, 286:L613-L619.
14. Aoki Y., Maeno T., Aoyagi K., Ueno M., Aoki F., Aoki N., Nakagawa J., Sando Y., Shimizu Y., Suga T., Arai M., Kurabayashi M. Respiration 2009, 77:311-319.
15. Paola R.D., Cuzzocrea S. PPAR Research 2007, 2007:63745.
16. Becker J., Delayre-Orthez C., Frossard N., Pons F. Fundamental & Clinical Pharmacology 2006, 20:429-447.
17. Maekawa T., Jin W., Ishii S. Molecular and Cellular Biology 2010, 30:613-625.
18. Scoditti E., Massaro M., Carluccio M.A., Distante A., Storelli C., De Caterina R. Cardiovascular Research 2010, 86:302-310.
19. Erikstein B.S., McCormack E., Tronstad K.J., Schwede F., Berge R., Gjertsen B.T. Leukemia Research 2010, 34:77-84.
20. Fredholm B.B., Chern Y., Franco R., Sitkovsky M. Progress in Neurobiology 2007, 83:263-276.
21. Chen J.F., Huang Z., Ma J., Zhu J., Moratalla R., Standaert D., Moskowitz M.A., Fink J.S., Schwarzschild M.A. Journal of Neuroscience 1999, 19:9192-9200.
22. Li W., Dai S., An J., Li P., Chen X., Xiong R., Liu P., Wang H., Zhao Y., Zhu M., Liu X., Zhu P., Chen J.F., Zhou Y. Neuroscience 2008, 151:1198-1207.
23. Xin W., Zhang L., Fan H., Jiang N., Wang T., Fu F. European Journal of Pharmaceutical Sciences 2011, 42:73-80.
24. Donadieu E., Hamdi W., Deveze A., Lucciano M., Lavieille J.P., Magnan J., Riva C. Acta Histochemica 2007, 109:177-184.
25. Desvergne B., Wahli W. Endocrine Reviews 1999, 20:649-688.
26. Chao F., Gong W., Zheng Y., Li Y., Huang G., Gao M., Li J., Kuruba R., Gao X., Li S., He F. Atherosclerosis 2010, 213:443-448.
27. Vamecq J., Latruffe N. Lancet 1999, 354:141-148.
28. Corton J.C., Anderson S.P., Stauber A. Annual Review of Pharmacology and Toxicology 2000, 40:491-518.
29. Spiegelman B.M. Diabetes 1998, 47:507-514.
30. Willson T.M., Lambert M.H., Kliewer S.A. Annual Review of Biochemistry 2001, 70:341-367.
31. Cuzzocrea S., Wayman N.S., Mazzon E., Dugo L., Di Paola R., Serraino I., Britti D., Chatterjee P.K., Caputi A.P., Thiemermann C. Molecular Pharmacology 2002, 61:997-1007.
32. Cuzzocrea S., Pisano B., Dugo L., Ianaro A., Maffia P., Patel N.S., Di Paola R., Ialenti A., Genovese T., Chatterjee P.K., Di Rosa M., Caputi A.P., Thiemermann C. European Journal of Pharmacology 2004, 483:79-93.
33. Standiford T.J., Keshamouni V.G., Reddy R.C. Proceedings of the American Thoracic Society 2005, 2:226-231.
34. Ishii H., Ishibashi M., Takayama M., Nishida T., Yoshida M. Respirology 2000, 5:325-331.
35. Okada M., Yan S.F., Pinsky D.J. The FASEB Journal 2002, 16:1861-1868.
36. Dugo L., Collin M., Cuzzocrea S., Thiemermann C. European Journal of Pharmacology 2004, 498:295-301.
37. Cuzzocrea S. Current Opinion in Pharmacology 2006, 6:263-270.
38. Hasko G., Pacher P. Journal of Leukocyte Biology 2008, 83:447-455.
39. Lappas C.M., Sullivan G.W., Linden J. Expert Opinion on Investigational Drugs 2005, 14:797-806.
40. Hasko G., Kuhel D.G., Chen J.F., Schwarzschild M.A., Deitch E.A., Mabley J.G., Marton A., Szabo C. The FASEB Journal 2000, 14:2065-2074.
41. Ricote M., Li A.C., Willson T.M., Kelly C.J., Glass C.K. Nature 1998, 391:79-82.
42. Peyrou M., Ramadori P., Bourgoin L., Foti M. PPAR Research 2012, 757803.
43. Choi Y.H., Kim H.I., Seong J.K., Yu D.Y., Cho H., Lee M.O., Lee J.M., Ahn Y.H., Kim S.J., Park J.H. FEBS Letters 2004, 557:73-80.
44. Mann J., Chu D.C., Maxwell A., Oakley F., Zhu N.L., Tsukamoto H., Mann D.A. Gastroenterology 2010, 138:705-714. (714 e701-704).
45. Jennewein C., von Knethen A., Schmid T., Brune B. Journal of Biological Chemistry 2010, 285:11846-11853.
46. Wang J., Song Y., Zhang Y., Xiao H., Sun Q., Hou N., Guo S., Wang Y., Fan K., Zhan D., Zha L., Cao Y., Li Z., Cheng X., Yang X. Cell Research 2012, 22:516-527.
47. Liu D., Zeng B.X., Shang Y. Physiological Research 2006, 55:291-299.
48. Hagiwara M., Brindle P., Harootunian A., Armstrong R., Rivier J., Vale W., Tsien R., Montminy M.R. Molecular and Cellular Biology 1993, 13:4852-4859.
49. Vallejo M., Gosse M.E., Beckman W., Habener J.F. Molecular and Cellular Biology 1995, 15:415-424.
50. Du K., Asahara H., Jhala U.S., Wagner B.L., Montminy M. Molecular and Cellular Biology 2000, 20:4320-4327.
51. Conkright M.D., Guzman E., Flechner L., Su A.I., Hogenesch J.B., Montminy M. Molecular Cell 2003, 11:1101-1108.