-
2
-
-
25144506835
-
Autophagy in cell death: an innocent convict
-
Levine B and Yuan J. Autophagy in cell death: an innocent convict? The Journal of Clinical Investigation. 2005; 115(10):2679-2688.
-
(2005)
The Journal of Clinical Investigation
, vol.115
, Issue.10
, pp. 2679-2688
-
-
Levine, B.1
Yuan, J.2
-
3
-
-
2442482810
-
Autophagy as a cell death and tumor suppressor mechanism
-
Gozuacik D and Kimchi A. Autophagy as a cell death and tumor suppressor mechanism. Oncogene. 2004; 23(16):2891-2906.
-
(2004)
Oncogene
, vol.23
, Issue.16
, pp. 2891-2906
-
-
Gozuacik, D.1
Kimchi, A.2
-
5
-
-
78649338141
-
Autophagy and the integrated stress response
-
Kroemer G, Marino G and Levine B. Autophagy and the integrated stress response. Molecular Cell. 2010; 40(2):280-293.
-
(2010)
Molecular Cell
, vol.40
, Issue.2
, pp. 280-293
-
-
Kroemer, G.1
Marino, G.2
Levine, B.3
-
7
-
-
33645156429
-
From acute ER stress to physiological roles of the Unfolded Protein Response
-
Wu J and Kaufman RJ. From acute ER stress to physiological roles of the Unfolded Protein Response. Cell Death and Differentiation. 2006; 13(3):374-384.
-
(2006)
Cell Death and Differentiation
, vol.13
, Issue.3
, pp. 374-384
-
-
Wu, J.1
Kaufman, R.J.2
-
8
-
-
57049117856
-
Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities
-
Kim I, Xu W and Reed JC. Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities. Nature Reviews Drug Discovery. 2008; 7(12):1013-1030.
-
(2008)
Nature Reviews Drug Discovery
, vol.7
, Issue.12
, pp. 1013-1030
-
-
Kim, I.1
Xu, W.2
Reed, J.C.3
-
9
-
-
24644432531
-
The SERCA pump as a therapeutic target: making a "smart bomb" for prostate cancer
-
Denmeade SR and Isaacs JT. The SERCA pump as a therapeutic target: making a "smart bomb" for prostate cancer. Cancer Biology & Therapy. 2005; 4(1):14-22.
-
(2005)
Cancer Biology & Therapy
, vol.4
, Issue.1
, pp. 14-22
-
-
Denmeade, S.R.1
Isaacs, J.T.2
-
11
-
-
34548037901
-
Connecting endoplasmic reticulum stress to autophagy by unfolded protein response and calcium
-
Hoyer-Hansen M and Jaattela M. Connecting endoplasmic reticulum stress to autophagy by unfolded protein response and calcium. Cell Death and Differentiation. 2007; 14(9):1576-1582.
-
(2007)
Cell Death and Differentiation
, vol.14
, Issue.9
, pp. 1576-1582
-
-
Hoyer-Hansen, M.1
Jaattela, M.2
-
12
-
-
33846189759
-
Control of macroautophagy by calcium, calmodulin-dependent kinase kinase-beta, and Bcl-2
-
Hoyer-Hansen M, Bastholm L, Szyniarowski P, Campanella M, Szabadkai G, Farkas T, Bianchi K, Fehrenbacher N, Elling F, Rizzuto R, Mathiasen IS and Jaattela M. Control of macroautophagy by calcium, calmodulin-dependent kinase kinase-beta, and Bcl-2. Molecular Cell. 2007; 25(2):193-205.
-
(2007)
Molecular Cell
, vol.25
, Issue.2
, pp. 193-205
-
-
Hoyer-Hansen, M.1
Bastholm, L.2
Szyniarowski, P.3
Campanella, M.4
Szabadkai, G.5
Farkas, T.6
Bianchi, K.7
Fehrenbacher, N.8
Elling, F.9
Rizzuto, R.10
Mathiasen, I.S.11
Jaattela, M.12
-
13
-
-
33751244535
-
Calpain is required for macroautophagy in mammalian cells
-
Demarchi F, Bertoli C, Copetti T, Tanida I, Brancolini C, Eskelinen EL and Schneider C. Calpain is required for macroautophagy in mammalian cells. The Journal of Cell Biology. 2006; 175(4):595-605.
-
(2006)
The Journal of Cell Biology
, vol.175
, Issue.4
, pp. 595-605
-
-
Demarchi, F.1
Bertoli, C.2
Copetti, T.3
Tanida, I.4
Brancolini, C.5
Eskelinen, E.L.6
Schneider, C.7
-
14
-
-
80053254762
-
Characterization of the CaMKKbeta-AMPK signaling complex
-
Green MF, Anderson KA and Means AR. Characterization of the CaMKKbeta-AMPK signaling complex. Cellular Signalling. 2011; 23(12):2005-2012.
-
(2011)
Cellular Signalling
, vol.23
, Issue.12
, pp. 2005-2012
-
-
Green, M.F.1
Anderson, K.A.2
Means, A.R.3
-
15
-
-
79551598347
-
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
-
Kim J, Kundu M, Viollet B and Guan KL. AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1. Nature Cell Biology. 2011; 13(2):132-141.
-
(2011)
Nature Cell Biology
, vol.13
, Issue.2
, pp. 132-141
-
-
Kim, J.1
Kundu, M.2
Viollet, B.3
Guan, K.L.4
-
16
-
-
79251587803
-
Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy
-
Egan DF, Shackelford DB, Mihaylova MM, Gelino S, Kohnz RA, Mair W, Vasquez DS, Joshi A, Gwinn DM, Taylor R, Asara JM, Fitzpatrick J, Dillin A, Viollet B, Kundu M, Hansen M, et al. Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy. Science. 2011; 331(6016):456-461.
-
(2011)
Science
, vol.331
, Issue.6016
, pp. 456-461
-
-
Egan, D.F.1
Shackelford, D.B.2
Mihaylova, M.M.3
Gelino, S.4
Kohnz, R.A.5
Mair, W.6
Vasquez, D.S.7
Joshi, A.8
Gwinn, D.M.9
Taylor, R.10
Asara, J.M.11
Fitzpatrick, J.12
Dillin, A.13
Viollet, B.14
Kundu, M.15
Hansen, M.16
-
19
-
-
0035863399
-
A novel response of cancer cells to radiation involves autophagy and formation of acidic vesicles
-
Paglin S, Hollister T, Delohery T, Hackett N, McMahill M, Sphicas E, Domingo D and Yahalom J. A novel response of cancer cells to radiation involves autophagy and formation of acidic vesicles. Cancer Research. 2001; 61(2):439-444.
-
(2001)
Cancer Research
, vol.61
, Issue.2
, pp. 439-444
-
-
Paglin, S.1
Hollister, T.2
Delohery, T.3
Hackett, N.4
McMahill, M.5
Sphicas, E.6
Domingo, D.7
Yahalom, J.8
-
20
-
-
0038743077
-
Induction of autophagic cell death in malignant glioma cells by arsenic trioxide
-
Kanzawa T, Kondo Y, Ito H, Kondo S and Germano I. Induction of autophagic cell death in malignant glioma cells by arsenic trioxide. Cancer Research. 2003; 63(9):2103-2108.
-
(2003)
Cancer Research
, vol.63
, Issue.9
, pp. 2103-2108
-
-
Kanzawa, T.1
Kondo, Y.2
Ito, H.3
Kondo, S.4
Germano, I.5
-
21
-
-
76249124608
-
Resveratrol promotes autophagic cell death in chronic myelogenous leukemia cells via JNK-mediated p62/SQSTM1 expression and AMPK activation
-
Puissant A, Robert G, Fenouille N, Luciano F, Cassuto JP, Raynaud S and Auberger P. Resveratrol promotes autophagic cell death in chronic myelogenous leukemia cells via JNK-mediated p62/SQSTM1 expression and AMPK activation. Cancer research. 2010; 70(3):1042-1052.
-
(2010)
Cancer research
, vol.70
, Issue.3
, pp. 1042-1052
-
-
Puissant, A.1
Robert, G.2
Fenouille, N.3
Luciano, F.4
Cassuto, J.P.5
Raynaud, S.6
Auberger, P.7
-
22
-
-
75749122303
-
Methods in mammalian autophagy research
-
Mizushima N, Yoshimori T and Levine B. Methods in mammalian autophagy research. Cell. 2010; 140(3):313-326.
-
(2010)
Cell
, vol.140
, Issue.3
, pp. 313-326
-
-
Mizushima, N.1
Yoshimori, T.2
Levine, B.3
-
23
-
-
33746108329
-
Lysosomal turnover, but not a cellular level, of endogenous LC3 is a marker for autophagy
-
Tanida I, Minematsu-Ikeguchi N, Ueno T and Kominami E. Lysosomal turnover, but not a cellular level, of endogenous LC3 is a marker for autophagy. Autophagy. 2005; 1(2):84-91.
-
(2005)
Autophagy
, vol.1
, Issue.2
, pp. 84-91
-
-
Tanida, I.1
Minematsu-Ikeguchi, N.2
Ueno, T.3
Kominami, E.4
-
24
-
-
53549084325
-
Does bafilomycin A1 block the fusion of autophagosomes with lysosomes
-
Klionsky DJ, Elazar Z, Seglen PO and Rubinsztein DC. Does bafilomycin A1 block the fusion of autophagosomes with lysosomes? Autophagy. 2008; 4(7):849-950.
-
(2008)
Autophagy
, vol.4
, Issue.7
, pp. 849-950
-
-
Klionsky, D.J.1
Elazar, Z.2
Seglen, P.O.3
Rubinsztein, D.C.4
-
25
-
-
79955755623
-
Mithramycin is a gene-selective Sp1 inhibitor that identifies a biological intersection between cancer and neurodegeneration
-
Sleiman SF, Langley BC, Basso M, Berlin J, Xia L, Payappilly JB, Kharel MK, Guo H, Marsh JL, Thompson LM, Mahishi L, Ahuja P, MacLellan WR, Geschwind DH, Coppola G, Rohr J, et al. Mithramycin is a gene-selective Sp1 inhibitor that identifies a biological intersection between cancer and neurodegeneration. The Journal of Neuroscience. 2011; 31(18):6858-6870.
-
(2011)
The Journal of Neuroscience
, vol.31
, Issue.18
, pp. 6858-6870
-
-
Sleiman, S.F.1
Langley, B.C.2
Basso, M.3
Berlin, J.4
Xia, L.5
Payappilly, J.B.6
Kharel, M.K.7
Guo, H.8
Marsh, J.L.9
Thompson, L.M.10
Mahishi, L.11
Ahuja, P.12
MacLellan, W.R.13
Geschwind, D.H.14
Coppola, G.15
Rohr, J.16
-
26
-
-
47249094223
-
Role of non-canonical Beclin 1-independent autophagy in cell death induced by resveratrol in human breast cancer cells
-
Scarlatti F, Maffei R, Beau I, Codogno P and Ghidoni R. Role of non-canonical Beclin 1-independent autophagy in cell death induced by resveratrol in human breast cancer cells. Cell Death and Differentiation. 2008; 15(8):1318-1329
-
(2008)
Cell Death and Differentiation
, vol.15
, Issue.8
, pp. 1318-1329
-
-
Scarlatti, F.1
Maffei, R.2
Beau, I.3
Codogno, P.4
Ghidoni, R.5
-
27
-
-
70349687405
-
Discovery of Atg5/Atg7-independent alternative macroautophagy
-
Nishida Y, Arakawa S, Fujitani K, Yamaguchi H, Mizuta T, Kanaseki T, Komatsu M, Otsu K, Tsujimoto Y and Shimizu S. Discovery of Atg5/Atg7-independent alternative macroautophagy. Nature. 2009; 461(7264):654-658.
-
(2009)
Nature
, vol.461
, Issue.7264
, pp. 654-658
-
-
Nishida, Y.1
Arakawa, S.2
Fujitani, K.3
Yamaguchi, H.4
Mizuta, T.5
Kanaseki, T.6
Komatsu, M.7
Otsu, K.8
Tsujimoto, Y.9
Shimizu, S.10
-
29
-
-
33845480131
-
Autophagy counterbalances endoplasmic reticulum expansion during the unfolded protein response
-
Bernales S, McDonald KL and Walter P. Autophagy counterbalances endoplasmic reticulum expansion during the unfolded protein response. PLoS Biology. 2006; 4(12):e423.
-
(2006)
PLoS Biology
, vol.4
, Issue.12
-
-
Bernales, S.1
McDonald, K.L.2
Walter, P.3
-
30
-
-
63849308518
-
Endoplasmic reticulum stress-mediated autophagy/apoptosis induced by capsaicin (8-methyl-Nvanillyl-6-nonenamide) and dihydrocapsaicin is regulated by the extent of c-Jun NH2-terminal kinase/extracellular signal-regulated kinase activation in WI38 lung epithelial fibroblast cells
-
Oh SH and Lim SC. Endoplasmic reticulum stress-mediated autophagy/apoptosis induced by capsaicin (8-methyl-Nvanillyl-6-nonenamide) and dihydrocapsaicin is regulated by the extent of c-Jun NH2-terminal kinase/extracellular signal-regulated kinase activation in WI38 lung epithelial fibroblast cells. The Journal of Pharmacology and Experimental Therapeutics. 2009; 329(1):112-122.
-
(2009)
The Journal of Pharmacology and Experimental Therapeutics
, vol.329
, Issue.1
, pp. 112-122
-
-
Oh, S.H.1
Lim, S.C.2
-
31
-
-
77953763757
-
Autophagy induction by capsaicin in malignant human breast cells is modulated by p38 and extracellular signal-regulated mitogen-activated protein kinases and retards cell death by suppressing endoplasmic reticulum stress-mediated apoptosis
-
Choi CH, Jung YK and Oh SH. Autophagy induction by capsaicin in malignant human breast cells is modulated by p38 and extracellular signal-regulated mitogen-activated protein kinases and retards cell death by suppressing endoplasmic reticulum stress-mediated apoptosis. Molecular Pharmacology. 2010; 78(1):114-125.
-
(2010)
Molecular Pharmacology
, vol.78
, Issue.1
, pp. 114-125
-
-
Choi, C.H.1
Jung, Y.K.2
Oh, S.H.3
-
32
-
-
77957367974
-
Inhibition of autophagy enhances anticancer effects of atorvastatin in digestive malignancies
-
Yang PM, Liu YL, Lin YC, Shun CT, Wu MS and Chen CC. Inhibition of autophagy enhances anticancer effects of atorvastatin in digestive malignancies. Cancer Research. 2010; 70(19):7699-7709.
-
(2010)
Cancer Research
, vol.70
, Issue.19
, pp. 7699-7709
-
-
Yang, P.M.1
Liu, Y.L.2
Lin, Y.C.3
Shun, C.T.4
Wu, M.S.5
Chen, C.C.6
-
33
-
-
0026591316
-
Oligomerization of indole-3-carbinol in aqueous acid
-
Grose KR and Bjeldanes LF. Oligomerization of indole-3-carbinol in aqueous acid. Chem Res Toxicol. 1992; 5(2):188-193.
-
(1992)
Chem Res Toxicol
, vol.5
, Issue.2
, pp. 188-193
-
-
Grose, K.R.1
Bjeldanes, L.F.2
-
34
-
-
75949106629
-
Oral diindolylmethane (DIM): pilot evaluation of a nonsurgical treatment for cervical dysplasia
-
Del Priore G, Gudipudi DK, Montemarano N, Restivo AM, Malanowska-Stega J and Arslan AA. Oral diindolylmethane (DIM): pilot evaluation of a nonsurgical treatment for cervical dysplasia. Gynecol Oncol. 2010; 116(3):464-467.
-
(2010)
Gynecol Oncol
, vol.116
, Issue.3
, pp. 464-467
-
-
Del Priore, G.1
Gudipudi, D.K.2
Montemarano, N.3
Restivo, A.M.4
Malanowska-Stega, J.5
Arslan, A.A.6
-
35
-
-
54249098378
-
Single-dose pharmacokinetics and tolerability of absorption-enhanced 3 3'-diindolylmethane in healthy subjects
-
Reed GA, Sunega JM, Sullivan DK, Gray JC, Mayo MS, Crowell JA and Hurwitz A. Single-dose pharmacokinetics and tolerability of absorption-enhanced 3,3'-diindolylmethane in healthy subjects. Cancer Epidemiol Biomarkers Prev. 2008; 17(10):2619-2624.
-
(2008)
Cancer Epidemiol Biomarkers Prev
, vol.17
, Issue.10
, pp. 2619-2624
-
-
Reed, G.A.1
Sunega, J.M.2
Sullivan, D.K.3
Gray, J.C.4
Mayo, M.S.5
Crowell, J.A.6
Hurwitz, A.7
-
36
-
-
79953293746
-
Pancreatic tumor suppression by benzyl isothiocyanate is associated with inhibition of PI3K/AKT/FOXO pathway
-
Boreddy SR, Pramanik KC and Srivastava SK. Pancreatic tumor suppression by benzyl isothiocyanate is associated with inhibition of PI3K/AKT/FOXO pathway. Clinical Cancer Research. 2011; 17(7):1784-1795.
-
(2011)
Clinical Cancer Research
, vol.17
, Issue.7
, pp. 1784-1795
-
-
Boreddy, S.R.1
Pramanik, K.C.2
Srivastava, S.K.3
-
37
-
-
1842865745
-
Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells
-
Kanzawa T, Germano IM, Komata T, Ito H, Kondo Y and Kondo S. Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells. Cell Death and Differentiation. 2004; 11(4):448-457.
-
(2004)
Cell Death and Differentiation
, vol.11
, Issue.4
, pp. 448-457
-
-
Kanzawa, T.1
Germano, I.M.2
Komata, T.3
Ito, H.4
Kondo, Y.5
Kondo, S.6
-
38
-
-
77958519207
-
A flowcytometric method for continuous measurement of intracellular Ca(2+) concentration
-
Vines A, McBean GJ and Blanco-Fernandez A. A flowcytometric method for continuous measurement of intracellular Ca(2+) concentration. Cytometry. 2010; 77(11):1091-1097.
-
(2010)
Cytometry
, vol.77
, Issue.11
, pp. 1091-1097
-
-
Vines, A.1
McBean, G.J.2
Blanco-Fernandez, A.3
-
39
-
-
59749104966
-
The role of STAT-3 in the induction of apoptosis in pancreatic cancer cells by benzyl isothiocyanate
-
Sahu RP and Srivastava SK. The role of STAT-3 in the induction of apoptosis in pancreatic cancer cells by benzyl isothiocyanate. J Natl Cancer Inst. 2009; 101(3):176-193.
-
(2009)
J Natl Cancer Inst
, vol.101
, Issue.3
, pp. 176-193
-
-
Sahu, R.P.1
Srivastava, S.K.2
|