Exploring Volatile General Anesthetic Binding to a Closed Membrane-Bound Bacterial Voltage-Gated Sodium Channel via Computation

PLoS Computational Biology

Volumn 9, Issue 6, 2013, Pages

  Raju, S G ^a   Barber, Annika F ^b   LeBard, David N ^c   Klein, Michael L ^a   Carnevale, Vincenzo ^a  

^a Temple University   (United States)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

^c YESHIVA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; BINDING SITES; MOLECULAR DYNAMICS; SODIUM;

BINDING-SITES; FLOODINGS; ION CHANNEL; ISOFLURANE; MECHANISM OF ACTION; MEMBRANE-BOUND; MOLECULAR BASIS; MOLECULAR TARGETS; SODIUM CHANNEL; STRUCTURAL MODELING;

ANESTHETICS;

ISOFLURANE; VOLTAGE GATED SODIUM CHANNEL;

ARTICLE; BINDING AFFINITY; DISSOCIATION; DRUG BINDING SITE; DRUG PROTEIN BINDING; HYDROPHOBICITY; MOLECULAR DYNAMICS; MOLECULAR MODEL; NONHUMAN; PROTEIN CONFORMATION;

BACTERIA (MICROORGANISMS);

EID: 84879516340     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1003090     Document Type: Article

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