Isoflurane inhibits NaChBac, a prokaryotic voltage-gated sodium channel

Journal of Pharmacology and Experimental Therapeutics

Volumn 322, Issue 3, 2007, Pages 1076-1083

  Ouyang, Wei ^a   Jih, Ting Yu ^a   Zhang, Tao Tao ^a   Correa, Ana M ^b   Hemmings Jr , Hugh C ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ETHER DERIVATIVE; INHALATION ANESTHETIC AGENT; ISOFLURANE; VOLTAGE GATED SODIUM CHANNEL;

ARTICLE; BACILLUS; BACILLUS HALODURANS; CELL LINE; CONCENTRATION RESPONSE; CONTROLLED STUDY; GENETIC TRANSFECTION; HALOGENATION; HUMAN; HUMAN CELL; IC 50; PATCH CLAMP; PRIORITY JOURNAL; PROKARYOTE; STEADY STATE;

ANESTHETICS, INHALATION; BACILLUS; BACTERIAL PROTEINS; CELL LINE; ELECTROPHYSIOLOGY; HUMANS; INHIBITORY CONCENTRATION 50; ION CHANNEL GATING; ISOFLURANE; PATCH-CLAMP TECHNIQUES; SODIUM CHANNELS; TRANSFECTION;

EID: 34548061532     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.107.122929     Document Type: Article

References (40)

1. Balser JR, Nuss HB, Chiamvimonvat N, Perez-Garcia MT, Marban E, and Tomaselli GF (1996a) External pore residue mediates slow inactivation in mu 1 rat skeletal muscle sodium channels. J Physiol 494:431-442.
2. Balser JR, Nuss HB, Romashko DN, Marban E, and Tomaselli GF (1996b) Functional consequences of lidocaine binding to slow-inactivated sodium channels. J Gen Physiol 107:643-658.
3. Baranauskas G and Martina M (2006) Sodium currents activate without a Hodgkinand-Huxley-type delay in central mammalian neurons. J Neurosci 26:671-684.
4. Catterall WA (2001) A one-domain voltage-gated sodium channel in bacteria. Science 294:2306-2308.
5. + channel in voltage-sensing. J Membr Biol 201:9-24.
6. Cordero-Morales JF, Cuello LG, Zhao Y, Jogini V, Cortes DM, Roux B, and Perozo E (2006) Molecular determinants of gating at the potassium-channel selectivity filter. Nat Struct Mol Biol 13:311-318.
7. + channel pore conformational changes induced by local anaesthetics. J Physiol 564:21-31.
8. Hamill OP, Marty A, Neher E, Sakmann B, and Sigworth FJ (1981) Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pfluegers Arch 391:85-100.
9. Hanck DA, Makielski JC, and Sheets MF (2000) Lidocaine alters activation gating of cardiac Na channels. Pflugers Arch 439:814-821.
10. Hemmings HC Jr., Akabas MH, Goldstein PA, Trudell JR, Orser BA, and Harrison NL (2005) Emerging mechanisms of general anesthetic action. Trends Pharmacol Sci 26:503-510.
11. + current affects resting potential and response to depolarization in simulated spinal sensory neurons. J Neurophysiol 86:1351-1364.
12. Hille B (1977) Local anesthetics: hydrophilic and hydrophobic pathways for the drug-receptor reaction. J Gen Physiol 69:497-515.
13. Hodgkin AL and Huxley AF (1952) A quantitative description of membrane current and its application to conduction and excitation in nerve. J Physiol 117:500-544.
14. Hondeghem LM and Katzung BG (1977) Time- and voltage-dependent interactions of antiarrhythmic drugs with cardiac sodium channels. Biochim Biophys Acta 472:373-398.
15. Hille B (2001) Ion Channels of Excitable Membranes, 3rd ed., pp 632-633, Sinauer Associates, Inc., Sunderland, MA.
16. Jurd R, Arras M, Lambert S, Drexler B, Siegwart R, Crestani F, Zaugg M, Vogt KE, Ledermann B, Antkowiak B, et al. (2003) General anesthetic actions in vivo strongly attenuated by a point mutation in the GABAA receptor beta3 subunit. FASEB J 17:250-252.
17. Kuzmenkin A, Bezanilla F, and Correa AM (2004) Gating of the bacterial sodium channel, NaChBac: voltage-dependent charge movement and gating currents. J Gen Physiol 124:349-356.
18. Li RA, Ennis IL, Tomaselli GF, and Marban E (2002) Structural basis of differences in isoform-specific gating and lidocaine block between cardiac and skeletal muscle sodium channels. Mol Pharmacol 61:136-141.
19. López-Barneo J, Hoshi T, Heinemann SH, and Aldrich RW (1993) Effects of external cations and mutations in the pore region on C-type inactivation of Shaker potassium channels. Receptors Channels 1:61-71.
20. Meir A, Ginsburg S, Butkevich A, Kachalsky SG, Kaiserman I, Ahdut R, Demirgoren S, and Rahamimoff R (1999) Ion channels in presynaptic nerve terminals and control of transmitter release. Physiol Rev 79:1019-1088.
21. + channels. J Membr Biol 201:1-8.
22. Ouyang W and Hemmings HC Jr (2005) Depression by isoflurane of the action potential and underlying voltage-gated ion currents in isolated rat neurohypophysial nerve terminals. J Pharmacol Exp Ther 312:801-808.
23. Ouyang W, Wang G, and Hemmings HC Jr (2003) Isoflurane and propofol inhibit voltage-gated sodium channels in isolated rat neurohypophysial nerve terminals. Mol Pharmacol 64:373-381.
24. Pavlov E, Bladen C, Winkfein R, Diao C, Dhaliwal P, and French RJ (2005) The pore, not cytoplasmic domains, underlies inactivation in a prokaryotic sodium channel. Biophys J 89:232-242.
25. + channels by local anesthetics. Science 265:1724-1728.
26. Ramos E and O'Leary ME (2004) State-dependent trapping of flecainide in the cardiac sodium channel. J Physiol 560:37-49.
27. Ratnakumari L, Vysotskaya TN, Duch DS, and Hemmings HC Jr (2000) Differential effects of anesthetic and nonanesthetic cyclobutanes on neuronal voltage-gated sodium channels. Anesthesiology 92:529-541.
28. Rehberg B, Xiao YH, and Duch DS (1996) Central nervous system sodium channels are significantly suppressed at clinical concentrations of volatile anesthetics. Anesthesiology 84:1223-1233.
29. Ren D, Navarro B, Xu H, Yue L, Shi Q, and Clapham DE (2001) A prokaryotic voltage-gated sodium channel. Science 294:2372-2375.
30. Sheets MF and Hanck DA (2003) Molecular action of lidocaine on the voltage sensors of sodium channels. J Gen Physiol 121:163-175.
31. + channels. J Pharmacol Exp Ther 309:987-994.
32. Stadnicka A, Kwok WM, Hartmann HA, and Bosnjak ZJ (1999) Effects of halothane and isoflurane on fast and slow inactivation of human heart hH1a sodium channels. Anesthesiology 90:1671-1683.
33. Taheri S, Halsey MJ, Liu J, Eger EI 2nd, Koblin DD, and Laster MJ (1991) What solvent best represents the site of action of inhaled anesthetics in humans, rats, and dogs? Anesth Analg 72:627-634.
34. 2+ and glutamate release. J Neurochem 53:1693-1699.
35. + channels contributes to the local anesthetic receptor. Mol Pharmacol 67:424-434.
36. + channels. J Gen Physiol 113:7-16.
37. + channels by local anesthetics in stably transfected mammalian cells: evidence for drug binding along the activation pathway. J Gen Physiol 124:691-701.
38. Wu XS, Sun JY, Evers AS, Crowder M, and Wu LG (2004) Isoflurane inhibits transmitter release and the presynaptic action potential. Anesthesiology 100:663-670.
39. Yu FH and Catterall WA (2003) Overview of the voltage-gated sodium channel family. Genome Biol 4:207.
40. Zhao Y, Scheuer T, and Catterall WA (2004) Reversed voltage-dependent gating of a bacterial sodium channel with proline substitutions in the S6 transmembrane segment. Proc Natl Acad Sci USA 101:17873-17878.