Apparent versus true gene expression changes of three hypoxia-related genes in autopsy derived tissue and the importance of normalisation

International Journal of Legal Medicine

Volumn 127, Issue 2, 2013, Pages 335-344

  Huth, Antje ^a,b   Vennemann, Benedikt ^c   Fracasso, Tony ^d,e   Lutz Bonengel, Sabine ^a   Vennemann, Marielle ^c  

^a UNIVERSITY OF FREIBURG   (Germany)

^b Eurofins Medinet Inc   (Germany)

^c HANNOVER MEDICAL SCHOOL   (Germany)

^d UNIVERSITY CENTER OF LEGAL MEDICINE   (Switzerland)

^e UNIVERSITY HOSPITAL MÜNSTER   (Germany)

Author keywords

Gene expression; Hypoxia; Normalisation; Post mortem tissue; RT qPCR

Indexed keywords

GLUCOSE TRANSPORTER 1; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; HIF1A PROTEIN, HUMAN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; VASCULOTROPIN A; VEGFA PROTEIN, HUMAN;

ADOLESCENT; ADULT; AGED; ANOXIA; ARTICLE; BRAIN; ESSENTIAL GENE; FEMALE; GENE EXPRESSION; GENETICS; HEART MUSCLE; HUMAN; MALE; METABOLISM; MIDDLE AGED; PATHOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SKELETAL MUSCLE; UPREGULATION; VERY ELDERLY;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANOXIA; BRAIN; FEMALE; GENE EXPRESSION; GENES, ESSENTIAL; GLUCOSE TRANSPORTER TYPE 1; GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASES; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MALE; MIDDLE AGED; MUSCLE, SKELETAL; MYOCARDIUM; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; UP-REGULATION; VASCULAR ENDOTHELIAL GROWTH FACTOR A; YOUNG ADULT;

EID: 84879505211     PISSN: 09379827     EISSN: 14371596     Source Type: Journal    
DOI: 10.1007/s00414-012-0787-2     Document Type: Article

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