Modulation of αvβ3- and α5β1-integrin-mediated adhesion by dehydro-β-amino acids containing peptidomimetics

European Journal of Medicinal Chemistry

Volumn 66, Issue , 2013, Pages 258-268

  Tolomelli, Alessandra ^a   Baiula, Monica ^a   Belvisi, Laura ^b   Viola, Angelo ^a   Gentilucci, Luca ^a   Troisi, Stefano ^a   Dattoli, Samantha Deianira ^a   Spampinato, Santi ^a   Civera, Monica ^b   Juaristi, Eusebio ^c   Escudero, Margarita ^c  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

^c DEPARTAMENTO DE FÍSICA   (Mexico)

Author keywords

Cell adhesion; Dehydro amino acids; Drug discovery; Peptidomimetic; Signaling

Indexed keywords

ARGINYLGLYCYLASPARTIC ACID; BETA AMINO ACID; CILENGITIDE; DEHYDRO BETA AMINO ACID DERIVATIVE; PEPTIDOMIMETIC AGENT; UNCLASSIFIED DRUG; VERY LATE ACTIVATION ANTIGEN 5; VITRONECTIN RECEPTOR; PEPTIDE DERIVATIVE;

AMINO ACID SEQUENCE; ARTICLE; CELL ADHESION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG STRUCTURE; HUMAN; HUMAN CELL; LIGAND BINDING; MODULATION; MOLECULAR DOCKING; MOLECULAR WEIGHT; PEPTIDOMICS; PROTEIN INTERACTION; ADHERENT CELL; ALLOSTERISM; AMINO TERMINAL SEQUENCE; CELL ADHESION ASSAY; CELL PROLIFERATION; CELL SURVIVAL; COMPARATIVE STUDY; CYCLIZATION; DRUG BINDING SITE; DRUG BIOAVAILABILITY; DRUG RECEPTOR BINDING; EXTRACELLULAR MATRIX; HYDROGEN BOND; INTRACELLULAR SIGNALING; K562 CELL LINE; PEPTIDE SYNTHESIS; PROTEIN PHOSPHORYLATION; REACTION TIME; STEREOCHEMISTRY; STEREOSPECIFICITY; STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION; WESTERN BLOTTING;

EID: 84879489470     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2013.05.050     Document Type: Article

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