메뉴 건너뛰기




Volumn 17, Issue 2, 2006, Pages 167-170

Synthesis of enantiomerically pure αvβ3 integrin ligands based on a 5,6-dihydropyridin-2-one scaffold

Author keywords

[No Author keywords available]

Indexed keywords

3 BROMO 4 METHYL 5,6 DIHYDROPYRIDIN 2 ONE DERIVATIVE; 5,6 DIHYDROPYRIDIN 2 ONE; ARGININE; ASPARTIC ACID; FIBRONECTIN; HETEROCYCLIC COMPOUND; LIGAND; PYRIDINE DERIVATIVE; UNCLASSIFIED DRUG; VITRONECTIN RECEPTOR;

EID: 32444450813     PISSN: 09574166     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetasy.2005.12.006     Document Type: Article
Times cited : (6)

References (37)
  • 27
    • 32444436081 scopus 로고    scopus 로고
    • note
    • Compound 1 was prepared starting from 2-bromo-3-methyl-2-butenoyl chloride and N-benzyl imine following the procedure reported later for 9a-9b.
  • 31
    • 0001740156 scopus 로고
    • L.A. Paquette John Wiley New York
    • J.A. Hyatt, and P.W. Raynolds L.A. Paquette Organic Reactions Vol. 45 1994 John Wiley New York 159 646
    • (1994) Organic Reactions , vol.45 , pp. 159-646
    • Hyatt, J.A.1    Raynolds, P.W.2
  • 35
    • 32444434889 scopus 로고    scopus 로고
    • note
    • The three-dimensional model of compound 9a was generated by HYPERCHEM 7.0 package, using AMBER force field. The model of the inhibitor was manually docked into the active site on the basis of docking studies for the binding of RGD active ligands.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.