Inhibition of CYP2E1 leads to decreased advanced glycated end product formation in high glucose treated ADH and CYP2E1 over-expressing VL-17A cells

Biochimica et Biophysica Acta - General Subjects

Volumn 1830, Issue 10, 2013, Pages 4407-4416

  Swaminathan, Kavitha ^a   Kumar, S Mathan ^a   Clemens, Dahn L ^b,c   Dey, Aparajita ^a  

^a ANNA UNIVERSITY   (India)

^b Veterans Administration   (United States)

^c UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

Advanced glycated end product; Cytochrome P4502E1 (CYP2E1); Hyperglycemia; Inhibition; Liver cell; Oxidative stress

Indexed keywords

4 METHYL PYRAZOLE; ADVANCED GLYCATION END PRODUCT; ALCOHOL DEHYDROGENASE; CYTOCHROME P450 2E1; GLUCOSE; PYRAZOLE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CELL STRAIN HEPG2; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; ENZYME INHIBITION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; LIPID PEROXIDATION; LIVER CELL; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; VL 17A CELL;

2′,7′-DICHLOROFLUORESCEIN DIACETATE; ADH; ADVANCED GLYCATED END PRODUCT; AGE; ALCOHOL DEHYDROGENASE; CYP2E1; CYTOCHROME P4502E1; CYTOCHROME P4502E1 (CYP2E1); DCF-DA; GLUTATHIONE; GSH; HYPERGLYCEMIA; INHIBITION; LIVER CELL; MEM; MINIMAL ESSENTIAL MEDIUM; MTT; NAFLD; NASH; NON-ALCOHOLIC FATTY LIVER DISEASE; NON-ALCOHOLIC STEATOHEPATITIS; OXIDATIVE STRESS; PBS; PHOSPHATE BUFFERED SALINE; REACTIVE OXYGEN SPECIES; ROS; THIAZOLYL BLUE TETRAZOLIUM BROMIDE;

ALCOHOL DEHYDROGENASE; ALLYL COMPOUNDS; CELL LINE; CYTOCHROME P-450 CYP2E1; GLUCOSE; GLYCOSYLATION END PRODUCTS, ADVANCED; HUMANS; OXIDATIVE STRESS; PYRAZOLES; REACTIVE OXYGEN SPECIES; SULFIDES;

EID: 84879474858     PISSN: 03044165     EISSN: 18728006     Source Type: Journal    
DOI: 10.1016/j.bbagen.2013.05.022     Document Type: Article

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