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Volumn 11, Issue 1, 2013, Pages

New insights into mechanisms behind miscarriage

Author keywords

Embryo Selection; Epidemiology; Genetics; Immunology; Miscarriage; Recurrent Miscarriage; Sperm DNA Integrity

Indexed keywords

ACETYLSALICYLIC ACID; CHORIONIC GONADOTROPIN BETA SUBUNIT; GRANULOCYTE COLONY STIMULATING FACTOR; HEPARIN; IMMUNOGLOBULIN; LUTEINIZING HORMONE; MESSENGER RNA; PLACEBO; PREDNISONE; PROGESTERONE; TUMOR NECROSIS FACTOR ALPHA INHIBITOR;

EID: 84879429797     PISSN: None     EISSN: 17417015     Source Type: Journal    
DOI: 10.1186/1741-7015-11-154     Document Type: Review
Times cited : (428)

References (74)
  • 1
    • 27944439741 scopus 로고    scopus 로고
    • Updated and revised nomenclature for description of early pregnancy events
    • Farquharson RG, Jauniaux E, Exalto N. Updated and revised nomenclature for description of early pregnancy events. Hum Reprod 2005, 20:3008-3011.
    • (2005) Hum Reprod , vol.20 , pp. 3008-3011
    • Farquharson, R.G.1    Jauniaux, E.2    Exalto, N.3
  • 2
    • 33749581700 scopus 로고    scopus 로고
    • Evidence-based guidelines for the investigation and medical treatment of recurrent miscarriage
    • Jauniaux E, Farquharson RG, Christiansen OB, Exalto N. Evidence-based guidelines for the investigation and medical treatment of recurrent miscarriage. Hum Reprod 2006, 21:2216-2222.
    • (2006) Hum Reprod , vol.21 , pp. 2216-2222
    • Jauniaux, E.1    Farquharson, R.G.2    Christiansen, O.B.3    Exalto, N.4
  • 4
    • 84867744217 scopus 로고    scopus 로고
    • Evaluation and treatment of recurrent pregnancy loss: a committee opinion
    • Practice Committee of the American Society for Reproductive Medicine
    • Practice Committee of the American Society for Reproductive Medicine Evaluation and treatment of recurrent pregnancy loss: a committee opinion. Fertil Steril 2012, 98:1103-1111. Practice Committee of the American Society for Reproductive Medicine.
    • (2012) Fertil Steril , vol.98 , pp. 1103-1111
  • 8
    • 72849110555 scopus 로고    scopus 로고
    • Detailed analysis of peripheral blood natural killer (NK) cells in women with recurrent miscarriage
    • King K, Smith S, Chapman M, Sacks G. Detailed analysis of peripheral blood natural killer (NK) cells in women with recurrent miscarriage. Hum Reprod 2010, 25:52-58.
    • (2010) Hum Reprod , vol.25 , pp. 52-58
    • King, K.1    Smith, S.2    Chapman, M.3    Sacks, G.4
  • 9
    • 57749174666 scopus 로고    scopus 로고
    • Uterine natural killer cells and angiogenesis in recurrent reproductive failure
    • Quenby S, Nik H, Innes B, Lash G, Turner M, Drury J, Bulmer J. Uterine natural killer cells and angiogenesis in recurrent reproductive failure. Hum Reprod 2009, 24:45-54.
    • (2009) Hum Reprod , vol.24 , pp. 45-54
    • Quenby, S.1    Nik, H.2    Innes, B.3    Lash, G.4    Turner, M.5    Drury, J.6    Bulmer, J.7
  • 10
    • 79960530853 scopus 로고    scopus 로고
    • Natural killer cells and pregnancy outcomes in women with recurrent miscarriage and infertility: a systematic review
    • Tang AW, Alfirevic Z, Quenby S. Natural killer cells and pregnancy outcomes in women with recurrent miscarriage and infertility: a systematic review. Hum Reprod 2011, 26:1971-1980.
    • (2011) Hum Reprod , vol.26 , pp. 1971-1980
    • Tang, A.W.1    Alfirevic, Z.2    Quenby, S.3
  • 11
    • 84862330211 scopus 로고    scopus 로고
    • Maternal homozygocity for a 14 base pair insertion in exon 8 of the HLA-G gene and carriage of HLA class II alleles restricting HY immunity predispose to unexplained secondary recurrent miscarriage and low birth weight in children born to these patients
    • Christiansen OB, Kolte AM, Dahl M, Larsen EC, Steffensen R, Nielsen HS, Hviid TV. Maternal homozygocity for a 14 base pair insertion in exon 8 of the HLA-G gene and carriage of HLA class II alleles restricting HY immunity predispose to unexplained secondary recurrent miscarriage and low birth weight in children born to these patients. Hum Immunol 2012, 73:699-705.
    • (2012) Hum Immunol , vol.73 , pp. 699-705
    • Christiansen, O.B.1    Kolte, A.M.2    Dahl, M.3    Larsen, E.C.4    Steffensen, R.5    Nielsen, H.S.6    Hviid, T.V.7
  • 14
    • 7044274078 scopus 로고    scopus 로고
    • Treatment of antiphospholipid syndrome in pregnancy - a systematic review of randomized therapeutic trials
    • Lassere M, Empson M. Treatment of antiphospholipid syndrome in pregnancy - a systematic review of randomized therapeutic trials. Thromb Res 2004, 114:419-426.
    • (2004) Thromb Res , vol.114 , pp. 419-426
    • Lassere, M.1    Empson, M.2
  • 15
    • 84858749181 scopus 로고    scopus 로고
    • Pathogenesis of infertility and recurrent pregnancy loss in thyroid autoimmunity
    • Twig G, Shina A, Amital H, Shoenfeld Y. Pathogenesis of infertility and recurrent pregnancy loss in thyroid autoimmunity. J Autoimmun 2012, 38:J275-J281.
    • (2012) J Autoimmun , vol.38
    • Twig, G.1    Shina, A.2    Amital, H.3    Shoenfeld, Y.4
  • 17
    • 77956584157 scopus 로고    scopus 로고
    • Increased pregnancy loss rate in thyroid antibody negative women with TSH levels between 2.5 and 5.0 in the first trimester of pregnancy
    • Negro R, Schwartz A, Gismondi R, Tinelli A, Mangieri T, Stagnaro-Green A. Increased pregnancy loss rate in thyroid antibody negative women with TSH levels between 2.5 and 5.0 in the first trimester of pregnancy. J Clin Endocrinol Metabol 2010, 95:E44-E48.
    • (2010) J Clin Endocrinol Metabol , vol.95
    • Negro, R.1    Schwartz, A.2    Gismondi, R.3    Tinelli, A.4    Mangieri, T.5    Stagnaro-Green, A.6
  • 20
    • 84866517445 scopus 로고    scopus 로고
    • Double stranded sperm DNA breaks, measured by Comet assay, are associated with unexplained recurrent miscarriage in couples without a female factor
    • Ribas-Maynou J, Garcia-Peiro A, Fernandez-Encinas A, Amengual MJ, Prada E, Cortes P, Navarro J, Benet J. Double stranded sperm DNA breaks, measured by Comet assay, are associated with unexplained recurrent miscarriage in couples without a female factor. PLoS One 2012, 7:e44679.
    • (2012) PLoS One , vol.7
    • Ribas-Maynou, J.1    Garcia-Peiro, A.2    Fernandez-Encinas, A.3    Amengual, M.J.4    Prada, E.5    Cortes, P.6    Navarro, J.7    Benet, J.8
  • 22
    • 0035988473 scopus 로고    scopus 로고
    • Recurrent miscarriage: a defect in nature's quality control?
    • Quenby S, Vince G, Farquharson R, Aplin J. Recurrent miscarriage: a defect in nature's quality control?. Hum Reprod 2002, 17:1959-1963.
    • (2002) Hum Reprod , vol.17 , pp. 1959-1963
    • Quenby, S.1    Vince, G.2    Farquharson, R.3    Aplin, J.4
  • 23
    • 0029927744 scopus 로고    scopus 로고
    • MUC1 as a cell surface and secretory component of endometrial epithelium: reduced levels in recurrent miscarriage
    • Aplin JD, Hey NA, Li TC. MUC1 as a cell surface and secretory component of endometrial epithelium: reduced levels in recurrent miscarriage. Am J Reprod Immunol 1996, 35:261-266.
    • (1996) Am J Reprod Immunol , vol.35 , pp. 261-266
    • Aplin, J.D.1    Hey, N.A.2    Li, T.C.3
  • 25
    • 78649493373 scopus 로고    scopus 로고
    • The molecular basis of recurrent pregnancy loss: impaired natural embryo selection
    • Teklenburg G, Salker M, Heijnen C, Macklon NS, Brosens JJ. The molecular basis of recurrent pregnancy loss: impaired natural embryo selection. Mol Hum Reprod 2010, 16:886-895.
    • (2010) Mol Hum Reprod , vol.16 , pp. 886-895
    • Teklenburg, G.1    Salker, M.2    Heijnen, C.3    Macklon, N.S.4    Brosens, J.J.5
  • 29
    • 84878511605 scopus 로고    scopus 로고
    • A modest, but significant effect of CGB5 gene promotor polymorphisms in modulating the risk of recurrent miscarriage
    • Rull KCO, Nagirnaja L, Steffensen R, Margus T, Laan M. A modest, but significant effect of CGB5 gene promotor polymorphisms in modulating the risk of recurrent miscarriage. Fertil Steril 2013, 99:1930-1936.
    • (2013) Fertil Steril , vol.99 , pp. 1930-1936
    • Rull, K.C.O.1    Nagirnaja, L.2    Steffensen, R.3    Margus, T.4    Laan, M.5
  • 30
    • 84858638963 scopus 로고    scopus 로고
    • Genetic polymorphisms and recurrent spontaneous abortions: an overview of current knowledge
    • Daher S, Mattar R, Gueuvoghlanian-Silva BY, Torloni MR. Genetic polymorphisms and recurrent spontaneous abortions: an overview of current knowledge. Am J Reprod Immunol 2012, 67:341-347.
    • (2012) Am J Reprod Immunol , vol.67 , pp. 341-347
    • Daher, S.1    Mattar, R.2    Gueuvoghlanian-Silva, B.Y.3    Torloni, M.R.4
  • 32
    • 77952548441 scopus 로고    scopus 로고
    • Body mass index and risk of miscarriage in women with recurrent miscarriage
    • Metwally M, Saravelos SH, Ledger WL, Li TC. Body mass index and risk of miscarriage in women with recurrent miscarriage. Fertil Steril 2010, 94:290-295.
    • (2010) Fertil Steril , vol.94 , pp. 290-295
    • Metwally, M.1    Saravelos, S.H.2    Ledger, W.L.3    Li, T.C.4
  • 33
    • 83455231302 scopus 로고    scopus 로고
    • Does obesity increase the risk of miscarriage in spontaneous conception: a systematic review
    • Boots C, Stephenson MD. Does obesity increase the risk of miscarriage in spontaneous conception: a systematic review. Semin Reprod Med 2011, 29:507-513.
    • (2011) Semin Reprod Med , vol.29 , pp. 507-513
    • Boots, C.1    Stephenson, M.D.2
  • 36
    • 0037338008 scopus 로고    scopus 로고
    • Conception, early pregnancy loss, and time to clinical pregnancy: a population-based prospective study
    • Wang X, Chen C, Wang L, Chen D, Guang W, French J. Conception, early pregnancy loss, and time to clinical pregnancy: a population-based prospective study. Fertil Steril 2003, 79:577-584.
    • (2003) Fertil Steril , vol.79 , pp. 577-584
    • Wang, X.1    Chen, C.2    Wang, L.3    Chen, D.4    Guang, W.5    French, J.6
  • 37
    • 0036629078 scopus 로고    scopus 로고
    • Conception to ongoing pregnancy: the 'black box' of early pregnancy loss
    • Macklon NS, Geraedts JP, Fauser BC. Conception to ongoing pregnancy: the 'black box' of early pregnancy loss. Hum Reprod Update 2002, 8:333-343.
    • (2002) Hum Reprod Update , vol.8 , pp. 333-343
    • Macklon, N.S.1    Geraedts, J.P.2    Fauser, B.C.3
  • 38
    • 0034709737 scopus 로고    scopus 로고
    • Maternal age and fetal loss: population based register linkage study
    • Nybo Andersen AM, Wohlfahrt J, Christens P, Olsen J, Melbye M. Maternal age and fetal loss: population based register linkage study. BMJ 2000, 320:1708-1712.
    • (2000) BMJ , vol.320 , pp. 1708-1712
    • Nybo Andersen, A.M.1    Wohlfahrt, J.2    Christens, P.3    Olsen, J.4    Melbye, M.5
  • 39
    • 0037460811 scopus 로고    scopus 로고
    • Effect of early oral clindamycin on late miscarriage and preterm delivery in asymptomatic women with abnormal vaginal flora and bacterial vaginosis: a randomised controlled trial
    • Ugwumadu A, Manyonda I, Reid F, Hay P. Effect of early oral clindamycin on late miscarriage and preterm delivery in asymptomatic women with abnormal vaginal flora and bacterial vaginosis: a randomised controlled trial. Lancet 2003, 361:983-988.
    • (2003) Lancet , vol.361 , pp. 983-988
    • Ugwumadu, A.1    Manyonda, I.2    Reid, F.3    Hay, P.4
  • 40
    • 84879787371 scopus 로고    scopus 로고
    • Epidemiology of recurrent pregnancy loss
    • London, UK: Informa Healthcare
    • Carp HJA. Epidemiology of recurrent pregnancy loss. Recurrent Pregnancy Loss 2007, London, UK: Informa Healthcare.
    • (2007) Recurrent Pregnancy Loss
    • Carp, H.J.A.1
  • 41
    • 48449103651 scopus 로고    scopus 로고
    • Multifactorial etiology of recurrent miscarriage and its scientific and clinical implications
    • Christiansen OB, Steffensen R, Nielsen HS, Varming K. Multifactorial etiology of recurrent miscarriage and its scientific and clinical implications. Gynecol Obstet Invest 2008, 66:257-267.
    • (2008) Gynecol Obstet Invest , vol.66 , pp. 257-267
    • Christiansen, O.B.1    Steffensen, R.2    Nielsen, H.S.3    Varming, K.4
  • 42
    • 0042623887 scopus 로고    scopus 로고
    • Embryoscopic and cytogenetic analysis of 233 missed abortions: factors involved in the pathogenesis of developmental defects of early failed pregnancies
    • Philipp T, Philipp K, Reiner A, Beer F, Kalousek DK. Embryoscopic and cytogenetic analysis of 233 missed abortions: factors involved in the pathogenesis of developmental defects of early failed pregnancies. Hum Reprod 2003, 18:1724-1732.
    • (2003) Hum Reprod , vol.18 , pp. 1724-1732
    • Philipp, T.1    Philipp, K.2    Reiner, A.3    Beer, F.4    Kalousek, D.K.5
  • 45
    • 0033023149 scopus 로고    scopus 로고
    • Fetal loss in Down syndrome pregnancies
    • Morris JK, Wald NJ, Watt HC. Fetal loss in Down syndrome pregnancies. Prenat Diagn 1999, 19:142-145.
    • (1999) Prenat Diagn , vol.19 , pp. 142-145
    • Morris, J.K.1    Wald, N.J.2    Watt, H.C.3
  • 46
    • 0033957901 scopus 로고    scopus 로고
    • Embryonic karyotype of abortuses in relation to the number of previous miscarriages
    • Ogasawara M, Aoki K, Okada S, Suzumori K. Embryonic karyotype of abortuses in relation to the number of previous miscarriages. Fertil Steril 2000, 73:300-304.
    • (2000) Fertil Steril , vol.73 , pp. 300-304
    • Ogasawara, M.1    Aoki, K.2    Okada, S.3    Suzumori, K.4
  • 47
    • 84872943055 scopus 로고    scopus 로고
    • Clinical applications of maternal plasma fetal DNA analysis: translating the fruits of 15 years of research
    • Chiu RW, Lo YM. Clinical applications of maternal plasma fetal DNA analysis: translating the fruits of 15 years of research. Clin Chem Lab Med 2013, 1:197-204.
    • (2013) Clin Chem Lab Med , vol.1 , pp. 197-204
    • Chiu, R.W.1    Lo, Y.M.2
  • 51
    • 78049433763 scopus 로고    scopus 로고
    • Clinical practice. Recurrent miscarriage
    • Branch DW, Gibson M, Silver RM. Clinical practice. Recurrent miscarriage. N Engl J Med 2010, 363:1740-1747.
    • (2010) N Engl J Med , vol.363 , pp. 1740-1747
    • Branch, D.W.1    Gibson, M.2    Silver, R.M.3
  • 52
    • 33645567027 scopus 로고    scopus 로고
    • Reproductive outcome after chromosome analysis in couples with two or more miscarriages: index [corrected]-control study
    • Franssen MT, Korevaar JC, van der Veen F, Leschot NJ, Bossuyt PM, Goddijn M. Reproductive outcome after chromosome analysis in couples with two or more miscarriages: index [corrected]-control study. BMJ 2006, 332:759-763.
    • (2006) BMJ , vol.332 , pp. 759-763
    • Franssen, M.T.1    Korevaar, J.C.2    van der Veen, F.3    Leschot, N.J.4    Bossuyt, P.M.5    Goddijn, M.6
  • 55
    • 43149085762 scopus 로고    scopus 로고
    • Can preimplantation genetic diagnosis overcome recurrent pregnancy failure?
    • Lalioti MD. Can preimplantation genetic diagnosis overcome recurrent pregnancy failure?. Curr Opin Obstet Gynecol 2008, 20:199-204.
    • (2008) Curr Opin Obstet Gynecol , vol.20 , pp. 199-204
    • Lalioti, M.D.1
  • 56
    • 84855906480 scopus 로고    scopus 로고
    • Investigation of systemic inflammatory response in first trimester pregnancy failure
    • Calleja-Agius J, Jauniaux E, Pizzey AR, Muttukrishna S. Investigation of systemic inflammatory response in first trimester pregnancy failure. Hum Reprod 2012, 27:349-357.
    • (2012) Hum Reprod , vol.27 , pp. 349-357
    • Calleja-Agius, J.1    Jauniaux, E.2    Pizzey, A.R.3    Muttukrishna, S.4
  • 58
    • 44249095888 scopus 로고    scopus 로고
    • Association of maternal killer-cell immunoglobulin-like receptors and parental HLA-C genotypes with recurrent miscarriage
    • Hiby SE, Regan L, Lo W, Farrell L, Carrington M, Moffett A. Association of maternal killer-cell immunoglobulin-like receptors and parental HLA-C genotypes with recurrent miscarriage. Hum Reprod 2008, 23:972-976.
    • (2008) Hum Reprod , vol.23 , pp. 972-976
    • Hiby, S.E.1    Regan, L.2    Lo, W.3    Farrell, L.4    Carrington, M.5    Moffett, A.6
  • 59
    • 0036856196 scopus 로고    scopus 로고
    • Low serum level of mannan-binding lectin is a determinant for pregnancy outcome in women with recurrent spontaneous abortion
    • Kruse C, Rosgaard A, Steffensen R, Varming K, Jensenius JC, Christiansen OB. Low serum level of mannan-binding lectin is a determinant for pregnancy outcome in women with recurrent spontaneous abortion. Am J Obstet Gynecol 2002, 187:1313-1320.
    • (2002) Am J Obstet Gynecol , vol.187 , pp. 1313-1320
    • Kruse, C.1    Rosgaard, A.2    Steffensen, R.3    Varming, K.4    Jensenius, J.C.5    Christiansen, O.B.6
  • 61
    • 79951947720 scopus 로고    scopus 로고
    • A systematic review of intravenous immunoglobulin for treatment of unexplained recurrent miscarriage
    • Ata B, Tan SL, Shehata F, Holzer H, Buckett W. A systematic review of intravenous immunoglobulin for treatment of unexplained recurrent miscarriage. Fertil Steril 2011, 95:1080-1085.
    • (2011) Fertil Steril , vol.95 , pp. 1080-1085
    • Ata, B.1    Tan, S.L.2    Shehata, F.3    Holzer, H.4    Buckett, W.5
  • 62
    • 9144243607 scopus 로고    scopus 로고
    • Heparin prevents antiphospholipid antibody-induced fetal loss by inhibiting complement activation
    • Girardi G, Redecha P, Salmon JE. Heparin prevents antiphospholipid antibody-induced fetal loss by inhibiting complement activation. Nat Med 2004, 10:1222-1226.
    • (2004) Nat Med , vol.10 , pp. 1222-1226
    • Girardi, G.1    Redecha, P.2    Salmon, J.E.3
  • 63
    • 84861064817 scopus 로고    scopus 로고
    • Sperm DNA damage: how relevant is it clinically?
    • Beshay VE, Bukulmez O. Sperm DNA damage: how relevant is it clinically?. Curr Opin Obstet Gynecol 2012, 24:172-179.
    • (2012) Curr Opin Obstet Gynecol , vol.24 , pp. 172-179
    • Beshay, V.E.1    Bukulmez, O.2
  • 64
    • 55849101155 scopus 로고    scopus 로고
    • Implantation of the human embryo requires Rac1-dependent endometrial stromal cell migration
    • Grewal S, Carver JG, Ridley AJ, Mardon HJ. Implantation of the human embryo requires Rac1-dependent endometrial stromal cell migration. Proc Natl Acad Sci USA 2008, 105:16189-16194.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 16189-16194
    • Grewal, S.1    Carver, J.G.2    Ridley, A.J.3    Mardon, H.J.4
  • 65
    • 77954265249 scopus 로고    scopus 로고
    • Something new about early pregnancy: decidual biosensoring and natural embryo selection
    • Brosens JJ, Gellersen B. Something new about early pregnancy: decidual biosensoring and natural embryo selection. Ultrasound Obstet Gynecol 2010, 36:1-5.
    • (2010) Ultrasound Obstet Gynecol , vol.36 , pp. 1-5
    • Brosens, J.J.1    Gellersen, B.2
  • 66
    • 77952551870 scopus 로고    scopus 로고
    • Preimplantation genetic diagnosis (PGD) improves pregnancy outcome for translocation carriers with a history of recurrent losses
    • Fischer J, Colls P, Escudero T, Munne S. Preimplantation genetic diagnosis (PGD) improves pregnancy outcome for translocation carriers with a history of recurrent losses. Fertil Steril 2010, 94:283-289.
    • (2010) Fertil Steril , vol.94 , pp. 283-289
    • Fischer, J.1    Colls, P.2    Escudero, T.3    Munne, S.4
  • 68
    • 28544442017 scopus 로고    scopus 로고
    • Expression of β-subunit of HCG genes during normal and failed pregnancy
    • Rull K, Laan M. Expression of β-subunit of HCG genes during normal and failed pregnancy. Hum Reprod 2005, 20:3360-3368.
    • (2005) Hum Reprod , vol.20 , pp. 3360-3368
    • Rull, K.1    Laan, M.2
  • 72
    • 83455258633 scopus 로고    scopus 로고
    • The importance of preconception counseling and early pregnancy monitoring
    • Saravelos SH, Regan L. The importance of preconception counseling and early pregnancy monitoring. Semin Reprod Med 2011, 29:557-568.
    • (2011) Semin Reprod Med , vol.29 , pp. 557-568
    • Saravelos, S.H.1    Regan, L.2
  • 74
    • 51449118702 scopus 로고    scopus 로고
    • Does high body mass index increase the risk of miscarriage after spontaneous and assisted conception? A meta-analysis of the evidence
    • Metwally M, Ong KJ, Ledger WL, Li TC. Does high body mass index increase the risk of miscarriage after spontaneous and assisted conception? A meta-analysis of the evidence. Fertil Steril 2008, 90:714-726.
    • (2008) Fertil Steril , vol.90 , pp. 714-726
    • Metwally, M.1    Ong, K.J.2    Ledger, W.L.3    Li, T.C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.