Maternal homozygocity for a 14 base pair insertion in exon 8 of the HLA-G gene and carriage of HLA class II alleles restricting HY immunity predispose to unexplained secondary recurrent miscarriage and low birth weight in children born to these patients

Human Immunology

Volumn 73, Issue 7, 2012, Pages 699-705

  Christiansen, Ole B ^a,b   Kolte, Astrid M ^a   Dahl, Mette ^c   Larsen, Elisabeth C ^a   Steffensen, Rudi ^b   Nielsen, Henriette S ^a   Hviid, Thomas V ^c  

^a International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health   (Denmark)

^b AALBORG UNIVERSITY HOSPITAL   (Denmark)

^c Copenhagen University Hospital ^*  (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

HLA ANTIGEN CLASS 2; HLA G ANTIGEN;

ALLELE; ARTICLE; BIRTH WEIGHT; CONTROLLED STUDY; DISEASE PREDISPOSITION; EXON; FEMALE; GENE DELETION; GENE INSERTION; GENOTYPE; GESTATIONAL AGE; HOMOZYGOSITY; HUMAN; LOW BIRTH WEIGHT; MAJOR CLINICAL STUDY; PERINATAL PERIOD; PRIORITY JOURNAL; SPONTANEOUS ABORTION;

ABORTION, HABITUAL; ALLELES; DNA MUTATIONAL ANALYSIS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; H-Y ANTIGEN; HISTOCOMPATIBILITY ANTIGENS CLASS II; HLA-G ANTIGENS; HOMOZYGOTE; HUMANS; IMMUNITY; INFANT, LOW BIRTH WEIGHT; INFANT, NEWBORN; MALE; MUTAGENESIS, INSERTIONAL; POLYMORPHISM, GENETIC; PROTEIN BINDING;

EID: 84862330211     PISSN: 01988859     EISSN: 18791166     Source Type: Journal    
DOI: 10.1016/j.humimm.2012.04.014     Document Type: Article

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