Inhibition of TGF-β1/Smad signal pathway is involved in the effect of Cordyceps sinensis against renal fibrosis in 5/6 nephrectomy rats

Food and Chemical Toxicology

Volumn 58, Issue , 2013, Pages 487-494

  Pan, Ming Ming ^a   Zhang, Ming Hui ^a   Ni, Hai Feng ^a   Chen, Jun Feng ^a   Xu, Min ^a   Phillips, Aled Owain ^b   Liu, Bi Cheng ^a  

^a MEDICAL SCHOOL OF SOUTHEAST UNIVERSITY   (China)

^b CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

Cordyceps sinensis; Renal fibrosis; TGF 1

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; BETA ACTIN; CALVASCULIN; HERBACEOUS AGENT; MESSENGER RNA; SMAD PROTEIN; SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD7 PROTEIN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2; TRANSFORMING GROWTH FACTOR BETA1; UVOMORULIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BETA ACTIN GENE; CONTROLLED STUDY; DRUG MECHANISM; EPITHELIAL MESENCHYMAL TRANSITION; EXPERIMENTAL RAT; GENE EXPRESSION; GLOMERULOSCLEROSIS; IN VIVO STUDY; INHIBITION KINETICS; KIDNEY FIBROSIS; KIDNEY FUNCTION; MALE; NEPHRECTOMY; NONHUMAN; OPHIOCORDYCEPS; PROTEIN EXPRESSION; RAT; SCORING SYSTEM; SIGNAL TRANSDUCTION; SMAD2 GENE; SMAD3 GENE; SMAD7 GENE; TRANSFORMING GROWTH FACTOR BETA1 GENE; UPREGULATION;

CORDYCEPS SINENSIS; RENAL FIBROSIS; TGF-Β1;

ANIMALS; BASE SEQUENCE; CORDYCEPS; DNA PRIMERS; FIBROSIS; KIDNEY DISEASES; MALE; NEPHRECTOMY; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; SMAD PROTEINS; TRANSFORMING GROWTH FACTOR BETA1;

CORDYCEPS SINENSIS; RATTUS;

EID: 84879312489     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2013.04.037     Document Type: Article

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