Sustained suppression of IL-13 by a vaccine attenuates airway inflammation and remodeling in mice

American Journal of Respiratory Cell and Molecular Biology

Volumn 48, Issue 5, 2013, Pages 540-549

  Ma, Yanbing ^a,b,c   Halayko, Andrew J ^a,b   Basu, Sujata ^a,b   Guan, Qingdong ^a   Weiss, Carolyn R ^a   Ma, Allan G ^d   HayGlass, Kent T ^a,b   Becker, Allan B ^a,b   Warrington, Richard J ^a   Peng, Zhikang ^a,b  

^a UNIVERSITY OF MANITOBA   (Canada)

^b Manitoba Institute of Child Health   (Canada)

^c INSTITUTE OF MEDICAL BIOLOGY   (China)

^d NONE

Author keywords

Airway remodeling; Asthma; IL 13; Inflammation; Vaccine

Indexed keywords

ALLERGEN; ALUMINUM POTASSIUM SULFATE; COLLAGEN; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; INTERLEUKIN 12P40; INTERLEUKIN 5; OVALBUMIN; RECOMBINANT INTERLEUKIN 13; TRANSFORMING GROWTH FACTOR BETA1; BRONCHOCONSTRICTING AGENT; CYTOKINE; INTERLEUKIN 13; METHACHOLINE CHLORIDE; VACCINE;

AIRWAY REMODELING; AIRWAY RESISTANCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREATHING MECHANICS; CHRONIC INFLAMMATION; CONTROLLED STUDY; CYTOKINE RESPONSE; DRUG EFFICACY; DRUG INDUCED DISEASE; DRUG INHIBITION; EOSINOPHIL; EXTRACELLULAR MATRIX; FEMALE; GOBLET CELL; HISTOLOGY; HYPERPLASIA; INFLAMMATORY CELL; LEUKOCYTE DIFFERENTIAL COUNT; LUNG COMPLIANCE; LUNG LAVAGE; MOUSE; NEUTROPHIL; NONHUMAN; OSCILLATION; RESPIRATORY TRACT ALLERGY; RESPIRATORY TRACT INFLAMMATION; VACCINATION; ANIMAL; ASTHMA; BAGG ALBINO MOUSE; ELASTICITY; IMMUNOLOGY; LUNG; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY;

AIRWAY REMODELING; AIRWAY RESISTANCE; ANIMALS; ASTHMA; BRONCHOALVEOLAR LAVAGE FLUID; BRONCHOCONSTRICTOR AGENTS; COLLAGEN; CYTOKINES; ELASTICITY; FEMALE; INTERLEUKIN-13; LUNG; METHACHOLINE CHLORIDE; MICE; MICE, INBRED BALB C; VACCINATION; VACCINES;

MLCS; MLOWN;

EID: 84879298475     PISSN: 10441549     EISSN: 15354989     Source Type: Journal    
DOI: 10.1165/rcmb.2012-0060OC     Document Type: Article

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