Dendritic cell activation, phagocytosis and CD69 expression on cognate T cells are suppressed by n-3 long-chain polyunsaturated fatty acids

Immunology

Volumn 139, Issue 3, 2013, Pages 386-394

  Teague, Heather ^a,b   Rockett, Benjamin Drew ^a,b   Harris, Mitchel ^a,b   Brown, David A ^a,b   Shaikh, Saame Raza ^a,b  

^a EAST CAROLINA UNIVERSITY   (United States)

^b EAST CAROLINA UNIVERSITY   (United States)

Author keywords

Dendritic cells; Diet; Fish oil

Indexed keywords

B7 ANTIGEN; CD69 ANTIGEN; DOCOSAHEXAENOIC ACID; FISH OIL; GLYCOPROTEIN P 15095; ICOSAPENTAENOIC ACID; LIPOPOLYSACCHARIDE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN EXPRESSION; ANTIGEN PRESENTATION; ARTICLE; CD4+ T LYMPHOCYTE; CELL ACTIVATION; CELL MEMBRANE; CONTROLLED STUDY; CYTOKINE RELEASE; DENDRITIC CELL; IN VITRO STUDY; MOUSE; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; T LYMPHOCYTE; VISCOSITY;

ANIMALS; ANTIGEN PRESENTATION; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; DENDRITIC CELLS; DIETARY FATS, UNSATURATED; DOCOSAHEXAENOIC ACIDS; EICOSAPENTAENOIC ACID; FATTY ACIDS, OMEGA-3; FISH OILS; HUMANS; LECTINS, C-TYPE; MALE; MICE; MICE, INBRED C57BL; PHAGOCYTOSIS; T-LYMPHOCYTES;

EID: 84879243325     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/imm.12088     Document Type: Article

References (46)

1. Duda MK, O'Shea KM, Tintinu A et al. Fish oil, but not flaxseed oil, decreases inflammation and prevents pressure overload-induced cardiac dysfunction. Cardiovasc Res 2009; 81:319-27.
2. Han YY, Lai SL, Ko WJ, Chou CH, Lai HS. Effects of fish oil on inflammatory modulation in surgical intensive care unit patients. Nutr Clin Pract 2012; 27:91-8.
3. Luu NT, Madden J, Calder PC et al. Dietary supplementation with fish oil modifies the ability of human monocytes to induce an inflammatory response. J Nutr 2007; 137:2769-74.
4. Oh DY, Talukdar S, Bae EJ et al. GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin-sensitizing effects. Cell 2010; 142:687-98.
5. Trebble TM, Stroud MA, Wootton SA et al. High-dose fish oil and antioxidants in Crohn's disease and the response of bone turnover: a randomised controlled trial. Br J Nutr 2005; 94:253-61.
6. McMurray DN, Jolly CA, Chapkin RS. Effects of dietary n-3 fatty acids on T cell activation and T cell receptor-mediated signaling in a murine model. J Infect Dis 2000; 182(Suppl 1):S103-7.
7. Guermouche B, Yessoufou A, Soulimane N, Merzouk H, Moutairou K, Hichami A, Khan NA. n-3 fatty acids modulate T-cell calcium signaling in obese macrosomic rats. Obes Res 2004; 12:1744-53.
8. Chapkin RS, Arrington JL, Apanasovich TV, Carroll RJ, McMurray DN. Dietary n-3 PUFA affect TcR-mediated activation of purified murine T cells and accessory cell function in co-cultures. Clin Exp Immunol 2002; 130:12-8.
9. Monk JM, Jia Q, Callaway E, Weeks B, Alaniz RC, McMurray DN, Chapkin RS. Th17 cell accumulation is decreased during chronic experimental colitis by (n-3) PUFA in Fat-1 mice. J Nutr 2012; 142:117-24.
10. Yog R, Barhoumi R, McMurray DN, Chapkin RS. n-3 polyunsaturated fatty acids suppress mitochondrial translocation to the immunologic synapse modulate calcium signaling in T cells. J Immunol 2010; 184:5865-73.
11. + T-cell activation is differentially modulated by bacteria-primed dendritic cells, but is generally down-regulated by n-3 polyunsaturated fatty acids. Immunology 2010; 129:338-50.
12. Zhang P, Smith R, Chapkin RS, McMurray DN. Dietary (n-3) polyunsaturated fatty acids modulate murine Th1/Th2 balance toward the Th2 pole by suppression of Th1 development. J Nutr 2005; 135:1745-51.
13. + T cells by affecting lipid raft formation. J Immunol 2008; 181:6236-43.
14. Rockett BD, Teague H, Harris M, Melton M, Williams J, Wassall SR, Shaikh SR. Fish oil increases raft size and membrane order of B cells accompanied by differential effects on function. J Lipid Res 2012; 53:674-85.
15. Rockett BD, Salameh M, Carraway K, Morrison K, Shaikh SR. n-3 PUFA improves fatty acid composition prevents palmitate-induced apoptosis differentially modifies B cell cytokine secretion in vitro and ex vivo. J Lipid Res 2010; 51:1284-97.
16. Steinman RM. Decisions about dendritic cells: past, present, and future. Annu Rev Immunol 2012; 30:1-22.
17. Kong W, Yen JH, Vassiliou E, Adhikary S, Toscano MG, Ganea D. Docosahexaenoic acid prevents dendritic cell maturation and in vitro and in vivo expression of the IL-12 cytokine family. Lipids Health Dis 2010; 9:12.
18. Kong W, Yen JH, Ganea D. Docosahexaenoic acid prevents dendritic cell maturation, inhibits antigen-specific Th1/Th17 differentiation and suppresses experimental autoimmune encephalomyelitis. Brain Behav Immun 2011; 25:872-82.
19. Draper E, Reynolds CM, Canavan M, Mills KH, Loscher CE, Roche HM. Omega-3 fatty acids attenuate dendritic cell function via NF-κB independent of PPARγ. J Nutr Biochem 2011; 22:784-90.
20. Zeyda M, Saemann MD, Stuhlmeier KM et al. Polyunsaturated fatty acids block dendritic cell activation and function independently of NF-κB activation. J Biol Chem 2005; 280:14293-301.
21. Shaikh SR, Rockett BD, Salameh M, Carraway K. Docosahexaenoic acid modifies the clustering and size of lipid rafts and the lateral organization and surface expression of MHC class I of EL4 cells. J Nutr 2009; 139:1632-9.
22. Rockett BD, Franklin A, Harris M, Teague H, Rockett A, Shaikh SR. Membrane raft organization is more sensitive to disruption by (n-3) PUFA than nonraft organization in EL4 and B cells. J Nutr 2011; 141:1041-8.
23. Geyeregger R, Zeyda M, Zlabinger GJ, Waldhausl W, Stulnig TM. Polyunsaturated fatty acids interfere with formation of the immunological synapse. J Leukoc Biol 2005; 77:680-8.
24. Zech T, Ejsing CS, Gaus K, de Wet B, Shevchenko A, Simons K, Harder T. Accumulation of raft lipids in T-cell plasma membrane domains engaged in TCR signalling. EMBO J 2009; 28:466-76.
25. Kim W, McMurray DN, Chapkin RS. n-3 polyunsaturated fatty acids-physiological relevance of dose. Prostaglandins Leukot Essent Fatty Acids 2010; 6:155-8.
26. Bays H. Rationale for prescription omega-3-acid ethyl ester therapy for hypertriglyceridemia: a primer for clinicians. Drugs Today (Barc) 2008; 44:205-46.
27. Miles EA, Calder PC. Influence of marine n-3 polyunsaturated fatty acids on immune function and a systematic review of their effects on clinical outcomes in rheumatoid arthritis. Br J Nutr 2012; 107(Suppl 2):S171-84.
28. Chen L, Arora M, Yarlagadda M, Oriss TB, Krishnamoorthy N, Ray A, Ray P. Distinct responses of lung and spleen dendritic cells to the TLR9 agonist CpG oligodeoxynucleotide. J Immunol 2006; 177:2373-83.
29. Hofmann J, Mair F, Greter M, Schmidt-Supprian M, Becher B. NIK signaling in dendritic cells but not in T cells is required for the development of effector T cells and cell-mediated immune responses. J Exp Med 2011; 208:1917-29.
30. Tan JK, Periasamy P, O'Neill HC. Delineation of precursors in murine spleen that develop in contact with splenic endothelium to give novel dendritic-like cells. Blood 2010; 115:3678-85.
31. Loike JD, Silverstein SC. A fluorescence quenching technique using trypan blue to differentiate between attached and ingested glutaraldehyde-fixed red blood cells in phagocytosing murine macrophages. J Immunol Methods 1983; 3:373-9.
32. Owen DM, Rentero C, Magenau A, Abu-Siniyeh A, Gaus K. Quantitative imaging of membrane lipid order in cells and organisms. Nat Protoc 2012; 7:24-35.
33. Folch J, Lees M, Sloane Stanley GH. A simple method for the isolation and purification of total lipids from animal tissues. J Biol Chem 1957; 226:497-509.
34. Malhotra V, Hogg N, Sim RB. Ligand binding by the p150, 95 antigen of U937 monocytic cells: properties in common with complement receptor type 3 (CR3). Eur J Immunol 1986; 16:1117-23.
35. Keizer GD, Te Velde AA, Schwarting R, Figdor CG, De Vries JE. Role of p150, 95 in adhesion, migration, chemotaxis and phagocytosis of human monocytes. Eur J Immunol 1987; 17:1317-22.
36. Wang H, Hao Q, Li QR, Yan XW, Ye S, Li YS, Li N, Li JS. Omega-3 polyunsaturated fatty acids affect lipopolysaccharide-induced maturation of dendritic cells through mitogen-activated protein kinases p38. Nutrition 2007; 23:474-82.
37. Nakajima K, Yamashita T, Kita T et al. Orally administered eicosapentaenoic acid induces rapid regression of atherosclerosis via modulating the phenotype of dendritic cells in LDL receptor-deficient mice. Arterioscler Thromb Vasc Biol 2011; 31:1963-72.
38. Zapata-Gonzalez F, Rueda F, Petriz J, Domingo P, Villarroya F, Diaz-Delfin J, de Madariaga MA, Domingo JC. Human dendritic cell activities are modulated by the omega-3 fatty acid, docosahexaenoic acid, mainly through PPARγ:RXR heterodimers: comparison with other polyunsaturated fatty acids. J Leukoc Biol 2008; 84:1172-82.
39. Schwerbrock NM, Karlsson EA, Shi Q, Sheridan PA, Beck MA. Fish oil-fed mice have impaired resistance to influenza infection. J Nutr 2009; 139:1588-94.
40. Myones BL, Dalzell JG, Hogg N, Ross GD. Neutrophil and monocyte cell surface p150, 95 has iC3b-receptor (CR4) activity resembling CR3. J Clin Invest 1988; 82:640-51.
41. Ihanus E, Uotila LM, Toivanen A, Varis M, Gahmberg CG. Red-cell ICAM-4 is a ligand for the monocyte/macrophage integrin CD11c/CD18: characterization of the binding sites on ICAM-4. Blood 2007; 109:802-10.
42. Dilioglou S, Cruse JM, Lewis RE. Function of CD80 and CD86 on monocyte- and stem cell-derived dendritic cells. Exp Mol Pathol 2003; 75:217-27.
43. Sanderson P, MacPherson GG, Jenkins CH, Calder PC. Dietary fish oil diminishes the antigen presentation activity of rat dendritic cells. J Leukoc Biol 1997; 62:771-7.
44. Kew S, Mesa MD, Tricon S, Buckley R, Minihane AM, Yaqoob P. Effects of oils rich in eicosapentaenoic and docosahexaenoic acids on immune cell composition and function in healthy humans. Am J Clin Nutr 2004; 79:674-81.
45. Stillwell W, Wassall SR. Docosahexaenoic acid: membrane properties of a unique fatty acid. Chem Phys Lipids 2003; 126:1-27.
46. Wong SW, Kwon MJ, Choi AM, Kim HP, Nakahira K, Hwang DH. Fatty acids modulate Toll-like receptor 4 activation through regulation of receptor dimerization and recruitment into lipid rafts in a reactive oxygen species-dependent manner. J Biol Chem 2009; 284:27384-92.