Inhibition of apelin expression switches endothelial cells from proliferative to mature state in pathological retinal angiogenesis

Angiogenesis

Volumn 16, Issue 3, 2013, Pages 723-734

  Kasai, Atsushi ^a   Ishimaru, Yuki ^b   Higashino, Kosuke ^b   Kobayashi, Kohei ^b   Yamamuro, Akiko ^b   Yoshioka, Yasuhiro ^b   Maeda, Sadaaki ^b  

^a OSAKA UNIVERSITY   (Japan)

^b SETSUNAN UNIVERSITY   (Japan)

Author keywords

Angiogenesis; Apelin; MCP 1; Pericytes; Smad; Vascular endothelial cells

Indexed keywords

APELIN; APELIN RECEPTOR; MONOCYTE CHEMOTACTIC PROTEIN 1; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SMAD3 PROTEIN; SMALL INTERFERING RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL MATURATION; CELL MIGRATION; CELL PROLIFERATION; CELL TRANSFORMATION; CONTROLLED STUDY; ENDOTHELIUM CELL; GENE SILENCING; IN VIVO STUDY; METABOLIC INHIBITION; MOUSE; NEWBORN; NONHUMAN; PATHOPHYSIOLOGY; PERICYTE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN INDUCTION; RETINA NEOVASCULARIZATION; RETINOPATHY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

ANALYSIS OF VARIANCE; ANIMALS; BLOTTING, WESTERN; CHEMOKINE CCL2; CULTURE MEDIA, CONDITIONED; ENDOTHELIAL CELLS; GENE KNOCKDOWN TECHNIQUES; IMMUNOHISTOCHEMISTRY; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MUSCLE, SMOOTH, VASCULAR; NEOVASCULARIZATION, PATHOLOGIC; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, G-PROTEIN-COUPLED; RETINAL VESSELS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; SMAD3 PROTEIN; TUMOR CELLS, CULTURED;

EID: 84879228585     PISSN: 09696970     EISSN: 15737209     Source Type: Journal    
DOI: 10.1007/s10456-013-9349-6     Document Type: Article

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