-
1
-
-
0035283073
-
Orphan G-protein-coupled receptors and natural ligand discovery
-
Howard AD, McAllister G, Feighner SD, Liu Q, Nargund RP, Van der Ploeg LH and Patchett AA. Orphan G-protein-coupled receptors and natural ligand discovery. Trends Pharmacol Sci 2001, 22: 132-140.
-
(2001)
Trends Pharmacol Sci
, vol.22
, pp. 132-140
-
-
Howard, A.D.1
McAllister, G.2
Feighner, S.D.3
Liu, Q.4
Nargund, R.P.5
Van Der Ploeg, L.H.6
Patchett, A.A.7
-
2
-
-
0032552988
-
Isolation and characterization of a novel endogenous peptide ligand for the human APJ receptor
-
Tatemoto K, Hosoya M, Habata Y, Fujii R, Kakegawa T, Zou MX and Kawamata Y, et al. Isolation and characterization of a novel endogenous peptide ligand for the human APJ receptor. Biochem Biophys Res Commun 1998, 251: 471-476.
-
(1998)
Biochem Biophys Res Commun
, vol.251
, pp. 471-476
-
-
Tatemoto, K.1
Hosoya, M.2
Habata, Y.3
Fujii, R.4
Kakegawa, T.5
Zou, M.X.6
Kawamata, Y.7
-
3
-
-
0037341188
-
Pharmacological and immunohistochemical characterization of the APJ receptor and its endogenous ligand apelin
-
Medhurst AD, Jennings CA, Robbins MJ, Davis RP, Ellis C, Winborn KY and Lawrie KW, et al. Pharmacological and immunohistochemical characterization of the APJ receptor and its endogenous ligand apelin. J Neurochem 2003, 84: 1162-1172.
-
(2003)
J Neurochem
, vol.84
, pp. 1162-1172
-
-
Medhurst, A.D.1
Jennings, C.A.2
Robbins, M.J.3
Davis, R.P.4
Ellis, C.5
Winborn, K.Y.6
Lawrie, K.W.7
-
4
-
-
0034647520
-
Molecular and functional characteristics of APJ. Tissue distribution of mRNA and interaction with the endogenous ligand apelin
-
Hosoya M, Kawamata Y, Fukusumi S, Fujii R, Habata Y, Hinuma S and Kitada C, et al. Molecular and functional characteristics of APJ. Tissue distribution of mRNA and interaction with the endogenous ligand apelin. J Biol Chem 2000, 275: 21061-21067.
-
(2000)
J Biol Chem
, vol.275
, pp. 21061-21067
-
-
Hosoya, M.1
Kawamata, Y.2
Fukusumi, S.3
Fujii, R.4
Habata, Y.5
Hinuma, S.6
Kitada, C.7
-
5
-
-
33646172369
-
Apelin and its receptor are expressed in human osteoblasts
-
Xie H, Tang SY, Cui RR, Huang J, Ren XH, Yuan LQ and Lu Y, et al. Apelin and its receptor are expressed in human osteoblasts. Regul Pept 2006, 134: 118-125.
-
(2006)
Regul Pept
, vol.134
, pp. 118-125
-
-
Xie, H.1
Tang, S.Y.2
Cui, R.R.3
Huang, J.4
Ren, X.H.5
Yuan, L.Q.6
Lu, Y.7
-
6
-
-
34247631507
-
Apelin (65-77) activates p70 S6 kinase and is mitogenic for umbilical endothelial cells
-
Masri B, Cornu M, Knibiehler B and Audigier Y. Apelin (65-77) activates p70 S6 kinase and is mitogenic for umbilical endothelial cells. FASEB J 2004, 3.
-
(2004)
FASEB J
, pp. 3
-
-
Masri, B.1
Cornu, M.2
Knibiehler, B.3
Audigier, Y.4
-
7
-
-
0035084443
-
[125I]-(Pyr1)Apelin-13 is a novel radioligand for localizing the APJ orphan receptor in human and rat tissues with evidence for a vasoconstrictor role in man
-
Katugampola SD, Matthewson SR and Davenport AP. [125I]-(Pyr1)Apelin-13 is a novel radioligand for localizing the APJ orphan receptor in human and rat tissues with evidence for a vasoconstrictor role in man. Br J Pharmacol 2001, 132: 1255-1260.
-
(2001)
Br J Pharmacol
, vol.132
, pp. 1255-1260
-
-
Katugampola, S.D.1
Matthewson, S.R.2
Davenport, A.P.3
-
8
-
-
1542300876
-
Immunocytochemical localization of the endogenous vasoactive peptide apelin to human vascular and endocardial endothelial cells
-
Kleinz MJ. Immunocytochemical localization of the endogenous vasoactive peptide apelin to human vascular and endocardial endothelial cells. Regul Pept 2004, 118: 119-125.
-
(2004)
Regul Pept
, vol.118
, pp. 119-125
-
-
Kleinz, M.J.1
-
9
-
-
12344312427
-
Immunocytochemical localisation of the apelin receptor, APJ, to human cardiomyocytes, vascular smooth muscle and endothelial cells
-
Kleinz MJ and Davenport AP. Immunocytochemical localisation of the apelin receptor, APJ, to human cardiomyocytes, vascular smooth muscle and endothelial cells. Regul Pept 2005, 126: 233-240.
-
(2005)
Regul Pept
, vol.126
, pp. 233-240
-
-
Kleinz, M.J.1
Davenport, A.P.2
-
10
-
-
33745048094
-
Apelin stimulates myosin light chain phosphorylation in vascular smooth muscle cells
-
Hashimoto T, Kihara M, Ishida J, Imai N, Yoshida S, Toya Y and Fukamizu A, et al. Apelin stimulates myosin light chain phosphorylation in vascular smooth muscle cells. Arterioscler Thromb Vasc Biol 2006, 26: 1267-1272.
-
(2006)
Arterioscler Thromb Vasc Biol
, vol.26
, pp. 1267-1272
-
-
Hashimoto, T.1
Kihara, M.2
Ishida, J.3
Imai, N.4
Yoshida, S.5
Toya, Y.6
Fukamizu, A.7
-
11
-
-
42649135532
-
Apelin-induced vascular smooth muscle cell proliferation: The regulation of cyclin D1
-
Li F, Li L, Qin X, Pan W, Feng F, Chen F and Zhu B, et al. Apelin-induced vascular smooth muscle cell proliferation: the regulation of cyclin D1. Front Biosci 2008, 13: 3786-3792.
-
(2008)
Front Biosci
, vol.13
, pp. 3786-3792
-
-
Li, F.1
Li, L.2
Qin, X.3
Pan, W.4
Feng, F.5
Chen, F.6
Zhu, B.7
-
13
-
-
0030273124
-
Expression of a new G protein-coupled receptor X-msr is associated with an endothelial lineage in Xenopus laevis
-
Devic E, Paquereau L, Vernier P, Knibiehler B and Audigier Y. Expression of a new G protein-coupled receptor X-msr is associated with an endothelial lineage in Xenopus laevis. Mech Dev 1996, 59: 129-140.
-
(1996)
Mech Dev
, vol.59
, pp. 129-140
-
-
Devic, E.1
Paquereau, L.2
Vernier, P.3
Knibiehler, B.4
Audigier, Y.5
-
14
-
-
0032811273
-
Amino acid sequence and embryonic expression of msr/apj, the mouse homolog of Xenopus X-msr and human APJ
-
Devic E, Rizzoti K, Bodin S, Knibiehler B and Audigier Y. Amino acid sequence and embryonic expression of msr/apj, the mouse homolog of Xenopus X-msr and human APJ. Mech Dev 1999, 84: 199-203.
-
(1999)
Mech Dev
, vol.84
, pp. 199-203
-
-
Devic, E.1
Rizzoti, K.2
Bodin, S.3
Knibiehler, B.4
Audigier, Y.5
-
15
-
-
7644230704
-
Apelin is a novel angiogenic factor in retinal endothelial cells
-
Kasai A, Shintani N, Oda M, Kakuda M, Hashimoto H, Matsuda T and Hinuma S, et al. Apelin is a novel angiogenic factor in retinal endothelial cells. Biochem Biophys Res Commun 2004, 325: 395-400.
-
(2004)
Biochem Biophys Res Commun
, vol.325
, pp. 395-400
-
-
Kasai, A.1
Shintani, N.2
Oda, M.3
Kakuda, M.4
Hashimoto, H.5
Matsuda, T.6
Hinuma, S.7
-
16
-
-
66149144223
-
Apelin prevents aortic aneurysm formation by inhibiting macrophage inflammation
-
Leeper NJ, Tedesco MM, Kojima Y, Schultz GM, Kundu RK, Ashley EA and Tsao PS, et al. Apelin prevents aortic aneurysm formation by inhibiting macrophage inflammation. Am J Physiol Heart Circ Physiol 2009, 296: H1329-H1335.
-
(2009)
Am J Physiol Heart Circ Physiol
, vol.296
-
-
Leeper, N.J.1
Tedesco, M.M.2
Kojima, Y.3
Schultz, G.M.4
Kundu, R.K.5
Ashley, E.A.6
Tsao, P.S.7
-
17
-
-
33745947584
-
Apelin, the ligand for the endothelial G-protein-coupled receptor, APJ, is a potent angiogenic factor required for normal vascular development of the frog embryo
-
Cox CM, D'Agostino SL, Miller MK, Heimark RL and Krieg PA. Apelin, the ligand for the endothelial G-protein-coupled receptor, APJ, is a potent angiogenic factor required for normal vascular development of the frog embryo. Dev Biol 2006, 296: 177-189.
-
(2006)
Dev Biol
, vol.296
, pp. 177-189
-
-
Cox, C.M.1
D'Agostino, S.L.2
Miller, M.K.3
Heimark, R.L.4
Krieg, P.A.5
-
18
-
-
34247591454
-
Paracrine and autocrine mechanisms of apelin signaling govern embryonic and tumor angiogenesis
-
Kalin RE, Kretz MP, Meyer AM, Kispert A, Heppner FL and Brandli AW. Paracrine and autocrine mechanisms of apelin signaling govern embryonic and tumor angiogenesis. Dev Biol 2007, 305: 599-614.
-
(2007)
Dev Biol
, vol.305
, pp. 599-614
-
-
Kalin, R.E.1
Kretz, M.P.2
Meyer, A.M.3
Kispert, A.4
Heppner, F.L.5
Brandli, A.W.6
-
19
-
-
33748800495
-
Xapelin and Xmsr are required for cardiovascular development in Xenopus laevis
-
Inui M, Fukui A, Ito Y and Asashima M. Xapelin and Xmsr are required for cardiovascular development in Xenopus laevis. Dev Biol 2006, 298: 188-200.
-
(2006)
Dev Biol
, vol.298
, pp. 188-200
-
-
Inui, M.1
Fukui, A.2
Ito, Y.3
Asashima, M.4
-
20
-
-
33846820545
-
Growth hormone induces apelin mRNA expression and secretion in mouse 3T3-L1 adipocytes
-
Kralisch S, Lossner U, Bluher M, Paschke R, Stumvoll M and Fasshauer M. Growth hormone induces apelin mRNA expression and secretion in mouse 3T3-L1 adipocytes. Regul Pept 2007, 139: 84-89.
-
(2007)
Regul Pept
, vol.139
, pp. 84-89
-
-
Kralisch, S.1
Lossner, U.2
Bluher, M.3
Paschke, R.4
Stumvoll, M.5
Fasshauer, M.6
-
21
-
-
58149471530
-
Apelin signaling modulates splanchnic angiogenesis and portosystemic collateral vessel formation in rats with portal hypertension
-
Tiani C, Garcia-Pras E, Mejias M, de Gottardi A, Berzigotti A, Bosch J and Fernandez M. Apelin signaling modulates splanchnic angiogenesis and portosystemic collateral vessel formation in rats with portal hypertension. J Hepatol 2009, 50: 296-305.
-
(2009)
J Hepatol
, vol.50
, pp. 296-305
-
-
Tiani, C.1
Garcia-Pras, E.2
Mejias, M.3
De Gottardi, A.4
Berzigotti, A.5
Bosch, J.6
Fernandez, M.7
-
22
-
-
47549104292
-
A possible role for hypoxia-induced apelin expression in enteric cell proliferation
-
Han S, Wang G, Qi X, Lee HM, Englander EW and Greeley GH Jr. A possible role for hypoxia-induced apelin expression in enteric cell proliferation. Am J Physiol Regul Integr Comp Physiol 2008, 294: R1832-R1839.
-
(2008)
Am J Physiol Regul Integr Comp Physiol
, vol.294
-
-
Han, S.1
Wang, G.2
Qi, X.3
Lee, H.M.4
Englander, E.W.5
Greeley Jr., G.H.6
-
23
-
-
44049090382
-
Reciprocal regulation of plasma apelin and vasopressin by osmotic stimuli
-
Azizi M, Iturrioz X, Blanchard A, Peyrard S, De Mota N, Chartrel N and Vaudry H, et al. Reciprocal regulation of plasma apelin and vasopressin by osmotic stimuli. J Am Soc Nephrol 2008, 19: 1015-1024.
-
(2008)
J Am Soc Nephrol
, vol.19
, pp. 1015-1024
-
-
Azizi, M.1
Iturrioz, X.2
Blanchard, A.3
Peyrard, S.4
De Mota, N.5
Chartrel, N.6
Vaudry, H.7
-
24
-
-
70350572293
-
Effect of diet-induced weight loss on plasma apelin and cytokine levels in individuals with the metabolic syndrome
-
Heinonen MV, Laaksonen DE, Karhu T, Karhunen L, Laitinen T, Kainulainen S and Rissanen A, et al. Effect of diet-induced weight loss on plasma apelin and cytokine levels in individuals with the metabolic syndrome. Nutr Metab Cardiovasc Dis 2009, 19: 626-633.
-
(2009)
Nutr Metab Cardiovasc Dis
, vol.19
, pp. 626-633
-
-
Heinonen, M.V.1
Laaksonen, D.E.2
Karhu, T.3
Karhunen, L.4
Laitinen, T.5
Kainulainen, S.6
Rissanen, A.7
-
25
-
-
0037868944
-
Venous dilator effect of apelin, an endogenous peptide ligand for the orphan APJ receptor, in conscious rats
-
Cheng X, Cheng XS and Pang CC. Venous dilator effect of apelin, an endogenous peptide ligand for the orphan APJ receptor, in conscious rats. Eur J Pharmacol 2003, 470: 171-175.
-
(2003)
Eur J Pharmacol
, vol.470
, pp. 171-175
-
-
Cheng, X.1
Cheng, X.S.2
Pang, C.C.3
-
26
-
-
2942711581
-
Regulatory roles for APJ, a seven-transmembrane receptor related to angiotensin-type 1 receptor in blood pressure in vivo
-
Ishida J, Hashimoto T, Hashimoto Y, Nishiwaki S, Iguchi T, Harada S and Sugaya T, et al. Regulatory roles for APJ, a seven-transmembrane receptor related to angiotensin-type 1 receptor in blood pressure in vivo. J Biol Chem 2004, 279: 26274-26279.
-
(2004)
J Biol Chem
, vol.279
, pp. 26274-26279
-
-
Ishida, J.1
Hashimoto, T.2
Hashimoto, Y.3
Nishiwaki, S.4
Iguchi, T.5
Harada, S.6
Sugaya, T.7
-
27
-
-
0036671721
-
G-protein-coupled receptors in human atherosclerosis: Comparison of vasoconstrictors (endothelin and thromboxane) with recently de-orphanized (urotensin-II, apelin and ghrelin) receptors
-
Katugampola SD, Kuc RE, Maguire JJ and Davenport AP. G-protein-coupled receptors in human atherosclerosis: comparison of vasoconstrictors (endothelin and thromboxane) with recently de-orphanized (urotensin-II, apelin and ghrelin) receptors. Clin Sci 2002, 103: S171-S175.
-
(2002)
Clin Sci
, vol.103
-
-
Katugampola, S.D.1
Kuc, R.E.2
Maguire, J.J.3
Davenport, A.P.4
-
28
-
-
0035876612
-
The novel peptide apelin lowers blood pressure via a nitric oxide-dependent mechanism
-
Tatemoto K, Takayama K, Zou MX, Kumaki I, Zhang W, Kumano K and Fujimiya M. The novel peptide apelin lowers blood pressure via a nitric oxide-dependent mechanism. Regul Pept 2001, 99: 87-92.
-
(2001)
Regul Pept
, vol.99
, pp. 87-92
-
-
Tatemoto, K.1
Takayama, K.2
Zou, M.X.3
Kumaki, I.4
Zhang, W.5
Kumano, K.6
Fujimiya, M.7
-
29
-
-
0033985447
-
Characterization of apelin, the ligand for the APJ receptor
-
Lee DK, Cheng R, Nguyen T, Fan T, Kariyawasam AP, Liu Y and Osmond DH, et al. Characterization of apelin, the ligand for the APJ receptor. J Neurochem 2000, 74: 34-41.
-
(2000)
J Neurochem
, vol.74
, pp. 34-41
-
-
Lee, D.K.1
Cheng, R.2
Nguyen, T.3
Fan, T.4
Kariyawasam, A.P.5
Liu, Y.6
Osmond, D.H.7
-
30
-
-
67650369897
-
Apelin and APJ receptor expression in granulosa and theca cells during different stages of follicular development in the bovine ovary: Involvement of apoptosis and hormonal regulation
-
Shimizu T, Kosaka N, Murayama C, Tetsuka M and Miyamoto A. Apelin and APJ receptor expression in granulosa and theca cells during different stages of follicular development in the bovine ovary: involvement of apoptosis and hormonal regulation. Anim Reprod Sci 2009, 116: 28-37.
-
(2009)
Anim Reprod Sci
, vol.116
, pp. 28-37
-
-
Shimizu, T.1
Kosaka, N.2
Murayama, C.3
Tetsuka, M.4
Miyamoto, A.5
-
31
-
-
0026526437
-
E2F: A link between the Rb tumor suppressor protein and viral oncoproteins
-
Nevins JR. E2F: a link between the Rb tumor suppressor protein and viral oncoproteins. Science 1992, 258: 424-429.
-
(1992)
Science
, vol.258
, pp. 424-429
-
-
Nevins, J.R.1
-
32
-
-
77951193861
-
ERK1/2 mediated the vasodilatation of apelin-13 on vascular rings of spontaneously hypertensive rat in vitro
-
Liu C, Li X, Chen F, Pan W, Fen F, Qing X and Li L, et al. ERK1/2 mediated the vasodilatation of apelin-13 on vascular rings of spontaneously hypertensive rat in vitro. Prog Biochem Biophys 2009, 36: 1578-1588.
-
(2009)
Prog Biochem Biophys
, vol.36
, pp. 1578-1588
-
-
Liu, C.1
Li, X.2
Chen, F.3
Pan, W.4
Fen, F.5
Qing, X.6
Li, L.7
|