High glucose and endothelial cell growth: Novel effects independent of autocrine TGF-β1 and hyperosmolarity

American Journal of Physiology - Cell Physiology

Volumn 284, Issue 6 53-6, 2003, Pages

  McGinn, S ^a   Poronnik, P ^a,b   King, M ^a   Gallery, E D M ^a   Pollock, C A ^a  

^a ROYAL NORTH SHORE HOSPITAL   (Australia)

^b UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Apoptosis; Diabetes mellitus; Endoreduplication; Endothelial cells; Transforming growth factor 1

Indexed keywords

ANTIBODY; CELL PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR; TRANSFORMING GROWTH FACTOR BETA1;

ARTICLE; AUTOCRINE EFFECT; CELL CYCLE S PHASE; CELL DEATH; CELL DESTRUCTION; CELL DISRUPTION; CELL GROWTH; CELL PROLIFERATION; CELL SIZE; CELL STIMULATION; CONTROLLED STUDY; CYTOARCHITECTURE; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; HYPEROSMOLARITY; HYPERTROPHY; INTERMETHOD COMPARISON; PRIORITY JOURNAL;

EID: 0038612958     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.00466.2002     Document Type: Article

References (51)

1. Ambuhl P, Amemiya M, Preisig PA, Moe OW, and Alpern RJ. Chronic hyperosmolality increases NHE3 activity in OKP cells. J Clin Invest 101: 170-177, 1998.
2. Baumgartner-Parzer SM, Wagner L, Pettermann M, Grillari J, Gessl A, and Waldhausl W. High-glucose-triggered apoptosis in cultured endothelial cells. Diabetes 44: 1323-1327, 1995.
3. Berk BC. Vascular smooth muscle growth: autocrine growth mechanisms. Physiol Rev 81: 999-1030, 2001.
4. Busch GL, Lang HJ, and Lang F. Studies on the mechanism of swelling-induced lysosomal alkalinization in vascular smooth muscle cells. Pflügers Arch 431: 690-696, 1996.
5. Cagliero E, Roth T, Taylor AW, and Lorenzi M. The effects of high glucose on human endothelial cell growth and gene expression are not mediated by transforming growth factor-beta. Lab Invest 73: 667-673, 1995.
6. Ceriello A, dello Russo P, Amatadi P, and Cerutti P. High glucose induces antioxidant enzymes in human endothelial cells: evidence linking high glucose with oxidative stress. Diabetes 45: 471-477, 1999.
7. Di Paolo S, Gesualdo L, Ranieri E, Grandaliano G, and Schena FP. High glucose concentration induces the overexpression of transforming growth factor-beta through the activation of a platelet-derived growth factor loop in human mesangial cells. Am J Pathol 149: 2095-2106, 1996.
8. Doyle JW, Smith RM, and Roth TP. The effect of hyperglycemia and insulin on the replication of cultured human microvascular endothelial cells. Horm Metab Res 29: 43-45, 1997.
9. Du XL, Sui GZ, Stockklauser-Farber K, Weiss J, Zink S, Schwippert B, Wu QX, Tschope D, and Rosen P. Introduction of apoptosis by high proinsulin and glucose in cultured human umbilical vein endothelial cells is mediated by reactive oxygen species. Diabetologia 41: 249-256, 1998.
10. Garfinkel S, Hu X, Prudovsky IA, McMahon GA, Kapnik EM, McDowell SD, and Maciag T. FGF-1-dependent proliferative and migratory responses are impaired in senescent human umbilical vein endothelial cells and correlate with the inability to signal tyrosine phosphorylation of fibroblast growth factor receptor-1 substrates. J Cell Biol 134: 783-791, 1996.
11. Gilbert RE, Wilkinson-Berka JL, Johnson DW, Cox A, Soulis T, Wu LL, Kelly DJ, Jerums G, Pollock CA, and Cooper ME. Renal expression of transforming growth factor-beta inducible gene-h3 (βig-h3) in normal and diabetic rats. Kidney Int 54: 1052-1062, 1998.
12. Grafi G. Cell cycle regulation of DNA replication: the endoreduplication perspective. Exp Cell Res 244: 372-378, 1998.
13. Graier WF, Grubenthal I, Dittrich P, Wascher TC, and Kostner GM. Intracellular mechanism of high D-glucose-induced modulation of vascular cell proliferation. Eur J Pharmacol 294: 221-229, 1995.
14. Han DC, Isono N, Hoffman BB, and Ziyadeh FN. High glucose stimulates proliferation and collagen type I synthesis in renal cortical fibroblasts: mediation by autocrine activation of TGF-beta. J Am Soc Nephrol 10: 1891-1899, 1999.
15. Hoffman BB, Sharma K, Zhu Y, and Ziyadeh FN. Transcriptional activation of transforming growth factor-beta1 in mesangial cell culture by high glucose concentration. Kidney Int 54: 1107-1116, 1998.
16. Jaffe EA, Nachman RL, Becker CG, and Minick CR. Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria. J Clin Invest 52: 2745-2756, 1973.
17. Jakobsen J, Sidenius P, Gundersen HV, and Osterby R. Quantitative changes of cerebral neocortical structure in insulin treated long term streptozocin-induced diabetes in rats. Diabetes 36: 597-601, 1987.
18. + exchange activity. Kidney Int 53: 1601-1607, 1998.
19. Kamal K, Du W, Mills I, and Sumpio BE. Antiproliferative effect of elevated glucose in human microvascular endothelial cells. J Cell Biochem 71: 491-501, 1998.
20. Klintworth GK, Valnickova Z, and Enghild JJ. Accumulation of beta ig-h3 gene product in corneas with granular dystrophy. Am J Pathol 152: 743-748, 1998.
21. Kolm V, Sauer U, Olgemooller B, and Schleicher ED. High glucose-induced TGF-β1 regulates mesangial production of heparan sulfate proteoglycan. Am J Physiol Renal Fluid Electrolyte Physiol 270: F812-F821, 1996.
22. Lang F, Ritter M, Gamper N, Huber S, Fillon S, Tanneur V, Lepple-Wienhues A, Szabo I, and Gulbins E. Cell volume in the regulation of cell proliferation and apoptotic cell death. Cell Physiol Biochem 10: 417-428, 2000.
23. Langham RA, Egan MK, Dowling JP, Gilbert RE, and Thomson NM. Transforming growth factor-beta and transforming growth factor-beta inducible gene-h3 (beta ig-h3) in non renal transplant cyclosporine nephropathy. Transplantation 72: 1826-1829, 2001.
24. Lorenzi M and Cagliero E. Pathobiology of endothelial and other vascular cells in diabetes mellitus. Call for data. Diabetes 40: 653-659, 1991.
25. Lorenzi M, Cagliero E, and Toledo S. Glucose toxicity for human endothelial cells in culture. Delayed replication, disturbed cell cycle, and accelerated death. Diabetes 34: 621-627, 1985.
26. Lorenzi M, Nordberg JA, and Toledo S. High glucose prolongs cell-cycle traversal of cultured human endothelial cells. Diabetes 36: 1261-1267, 1987.
27. Maciag T, Cerundolo J, Ilsley S, Kelley PR, and Forand R. An endothelial cell growth factor from bovine hypothalamus: identification and partial characterization. Proc Natl Acad Sci USA 76: 5674-5678, 1979.
28. Mizutani M, Kern TS, and Lorenzi M. Accelerated death of retinal microvascular cells in human and experimental diabetic retinopathy. J Clin Invest 97: 2883-2890, 1996.
29. Mogyorosi A, Kapoor A, Isono M, Kapoor S, Sharma K, and Ziyadeh FN. Utility of serum and urinary transforming growth factor-beta levels as markers of diabetic nephropathy. Nephron 86: 234-235, 2000.
30. Muller G, Behrens J, Nussbaumer U, Bohlen P, and Birchmeier W. Inhibitory action of transforming growth factor beta on endothelial cells. Proc Natl Acad Sci USA 84: 5600-5604, 1987.
31. Myoken Y, Kan M, Sato GH, McKeehan WL, and Sato JD. Bifunctional effects of transforming growth factor-beta (TGF-beta) on endothelial cell growth correlate with phenotypes of TGF-beta binding sites. Exp Cell Res 191: 299-304, 1990.
32. Nakagami H, Morishita R, Yamamoto K, Yoshimura SI, Taniyama Y, Aoki M, Matsubara H, Kim S, Kaneda Y, and Ogihara T. Phosphorylation of MAPK downstream of bax-caspase 3 leads to cell death induced by D glucose in human endothelial cells. Diabetes 50: 1472-1481, 2001.
33. O'Brien ER, Bennett KL, Garvin MR, Zderic TW, Hinohara T, Simpson JB, Kimura T, Nobuyoshi M, Mizgala H, Purchio A, and Schwartz SM. Beta ig-h3, a transforming growth factor-beta-inducible gene, is overexpressed in atherosclerotic vessels. Arterioscler Thromb Vasc Biol 16: 576-584, 1996.
34. Pascal MM, Forrester JV, and Knott RM. Glucose-mediated regulation of transforming growth factor-beta (TGF-beta) and TGF-beta receptors in human retinal endothelial cells. Curr Eye Res 19: 162-170, 1999.
35. Perella MA, Yoshizumu M, Fen Z, Tsai JC, Haiah CM, Kourenbanea J, and Lee ME. Transforming growth factor β1, but not dexamethasone, downregulates nitric oxide synthase mRNA after its induction by interleukin 1 in rat smooth muscle cells. J Biol Chem 269: 14595-14600, 1994.
36. Ravid K, Lu J, Zimmet JM, and Jones MR. Roads to polyploidy: the megakaryocyte example. J Cell Physiol 190: 7-20, 2002.
37. Risso A, Mercuri F, Quagliaro L, Damante G, and Ceriello A. Intermittent high glucose enhances apoptosis in human umbilical vein endothelial cells in culture. Am J Physiol Endocrinol Metab 281: E924-E930, 2001.
38. Rocco MV, Chen Y, Goldfarb S, and Ziyadeh FN. Elevated glucose stimulates TGF-beta gene expression and bioactivity in proximal tubule. Kidney Int 41: 107-114, 1992.
39. Shankland SJ, Scholey JW, Ly H, and Thai K. Expression of transforming growth factor-beta 1 during diabetic renal hypertrophy. Kidney Int 46: 430-442, 1994.
40. Shankland SJ and Wolf G. Cell cycle regulatory proteins in renal disease: role of hypertrophy, proliferation and apoptosis. Am J Physiol Renal Physiol 278: F515-F529, 2000.
41. Sharma K and Ziyadeh FN. Hyperglycemia and diabetic kidney disease. The case for transforming growth factor-beta as a key mediator. Diabetes 44: 1139-1146, 1995.
42. The Diabetes Control and Complications Trial Research Group. The effect of intensive treatment of diabetes on the development, and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med 329: 977-986, 1993.
43. The UK Prospective Diabetes Study (UKPDS) Group. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment, and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet 352: 837-853, 1998.
44. Tilton RG, Faller AM, Burkhardt JK, Hoffmann PL, Kilo C, and Williamson JR. Pericyte degeneration and acellular capillaries are increased in the feet of human diabetic patients. Diabetologia 28: 895-900, 1985.
45. Tsukada T, Eguchi K, Migita K, Kawabe Y, Kawakami A, Matsuoka N, Takashima H, Mizokami A, and Nagataki S. Transforming growth factor beta 1 induces apoptotic cell death in cultured human umbilical vein endothelial cells with down-regulated expression of bcl-2. Biochem Biophys Res Commun 210: 1076-1082, 1995.
46. Vranes D, Cooper ME, and Dilley RJ. Cellular mechanisms of diabetic vascular hypertrophy. Microvasc Res 57: 8-18, 1999.
47. Waldegger S, Busch GL, Kaba NK, Zempel G, Ling H, Heidland A, Haussinger D, and Lang F. Effect of cellular hydration on protein metabolism. Miner Electrolyte Metab 23: 201-205, 1997.
48. Wolf G. Molecular mechanisms of renal hypertrophy: role of p27Kip1. Kidney Int 56: 1262-1265, 1999.
49. Kip1, an inhibitor of cyclin-dependent kinases. Am J Pathol 158: 1091-1100, 2001.
50. Wu QD, Wang JH, Fennessy F, Redmond HP, and Bouchier-Hayes D. Taurine prevents high-glucose-induced human vascular endothelial cell apoptosis. Am J Physiol Cell Physiol 277: C1229-C1238, 1999.
51. Yan Q and Sage EH. Transforming growth factor-betal induces apoptotic cell death in cultured retinal endothelial cells but not pericytes: association with decreased expression of p21waf1/cip1. J Cell Biochem 70: 70-83, 1998.