Nitric oxide inhibits lipopolysaccharide-induced inducible nitric oxide synthase expression and its own production through the cGMP signaling pathway in murine microglia BV-2 cells

Journal of Pharmacological Sciences

Volumn 113, Issue 2, 2010, Pages 153-160

  Yoshioka, Yasuhiro ^a   Takeda, Nobuo ^a   Yamamuro, Akiko ^a   Kasai, Atsushi ^a   Maeda, Sadaaki ^a  

^a SETSUNAN UNIVERSITY   (Japan)

Author keywords

Guanosine 3 ,5 cyclic monophosphate (cGMP); Inducible nitric oxide synthase (iNOS); Microglia; Negative feedback regulation; Nitric oxide (No)

Indexed keywords

3,3 BIS(2 AMINOETHYL) 1 HYDROXY 2 OXOTRIAZENE; 6 ANILINO 5,8 QUINOLINEQUINONE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CYCLIC GMP; DIBUTYRYL CYCLIC GMP; GUANYLATE CYCLASE; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; NITRIC OXIDE; STRESS ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE INHIBITOR;

ANIMAL CELL; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; MICROGLIA; MOUSE; NEGATIVE FEEDBACK; NONHUMAN; PROTEIN EXPRESSION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; ANIMAL; BIOSYNTHESIS; CELL CULTURE; CHEMICAL PHENOMENA; DOSE RESPONSE; ENZYMOLOGY; METABOLISM; PHYSIOLOGY;

ANIMALS; CELLS, CULTURED; CYCLIC GMP; DEPRESSION, CHEMICAL; DOSE-RESPONSE RELATIONSHIP, DRUG; LIPOPOLYSACCHARIDES; MICE; MICROGLIA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; SIGNAL TRANSDUCTION;

EID: 77953862462     PISSN: 13478613     EISSN: 13478648     Source Type: Journal    
DOI: 10.1254/jphs.10060FP     Document Type: Article

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