In vitro modification of substituted cysteines as tool to study receptor functionality and structure-activity relationships

Analytical Biochemistry

Volumn 439, Issue 2, 2013, Pages 173-183

  Rathmann, Daniel ^a   Pedragosa Badia, Xavier ^a   Beck Sickinger, Annette G ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

G protein coupled receptor; Methanethiosulfonate; Prolactin releasing peptide; Structure activity relationship; Substituted cysteine accessibility method

Indexed keywords

PEPTIDES; REAGENTS; SIGNAL TRANSDUCTION; STRUCTURES (BUILT OBJECTS);

CYSTEINE SUBSTITUTIONS; G PROTEIN COUPLED RECEPTORS; METHANETHIOSULFONATE; NEGATIVELY CHARGED; PROTEINOGENIC AMINO ACIDS; SIDE CHAIN MODIFICATIONS; STRUCTURE ACTIVITY RELATIONSHIPS; SUBSTITUTED CYSTEINE ACCESSIBILITY METHOD;

AMINO ACIDS;

CYSTEINE; G PROTEIN COUPLED RECEPTOR; PROLACTIN RELEASING FACTOR;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; IN VITRO STUDY; LIGAND BINDING; MOLECULAR MIMICRY; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION; WILD TYPE;

EID: 84879205950     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2013.04.015     Document Type: Article

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