Ellipticine binds to a human telomere sequence: An additional mode of action as a putative anticancer agent?

Biochemistry

Volumn 52, Issue 24, 2013, Pages 4127-4137

  Ghosh, Saptaparni ^a   Kar, Anirban ^b   Chowdhury, Shantanu ^b   Dasgupta, Dipak ^a  

^a SAHA INSTITUTE OF NUCLEAR PHYSICS   (India)

^b CSIR INSTITUTE OF GENOMICS AND INTEGRATIVE BIOLOGY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

AMPLIFICATION PROTOCOLS; ANTICANCER PROPERTIES; BREAST CANCER CELLS; G-QUADRUPLEX STRUCTURE; HUMAN TELOMERE SEQUENCES; HUMAN TELOMERIC DNA; POTENTIAL ANTICANCER AGENTS; STRUCTURAL PERTURBATION;

CELL CULTURE; DNA; STOICHIOMETRY;

DNA SEQUENCES;

ELLIPTICINE; GUANINE QUADRUPLEX; K RAS PROTEIN; MYC PROTEIN; TELOMERASE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BINDING COMPETITION; BREAST CANCER; CALORIMETRY; CANCER CELL CULTURE; CIRCULAR DICHROISM; COMPETITIVE INHIBITION; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DNA SEQUENCE; ENTROPY; ENZYME ACTIVITY; FLUORESCENCE SPECTROSCOPY; HUMAN; HUMAN CELL; ISOTHERMAL TITRATION CALORIMETRY; PRIORITY JOURNAL; PROTEIN MOTIF; PROTEIN STABILITY; SEQUENCE ANALYSIS; SPECTROSCOPY; STOICHIOMETRY; TELOMERE; THERMOSTABILITY;

ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CALORIMETRY, DIFFERENTIAL SCANNING; CELL LINE, TUMOR; CIRCULAR DICHROISM; DNA; ELLIPTICINES; FEMALE; G-QUADRUPLEXES; HUMANS; INTERCALATING AGENTS; NUCLEIC ACID CONFORMATION; PROTEIN BINDING; SPECTROMETRY, FLUORESCENCE; TELOMERE;

EID: 84879200649     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi400080t     Document Type: Article

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