A selective high-Affinity antagonist of the P2Y14 receptor inhibits udp-glucose-stimulated chemotaxis of human neutrophilss

Molecular Pharmacology

Volumn 84, Issue 1, 2013, Pages 41-49

  Barrett, Matthew O ^a   Sesma, Juliana I ^b   Ball, Christopher B ^a   Jayasekara, P Suresh ^c   Jacobson, Kenneth A ^d   Lazarowski, Eduardo R ^b   Harden, T Kendall ^a,c  

^a Departments of Pharmacology   (United States)

^b Departments of Medicine and Pediatrics   (United States)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^d NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 NAPHTHOIC ACID DERIVATIVE; 4 [(PIPERIDIN 4 YL) PHENYL] 7 [4 (TRIFLUOROMETHYL) PHENYL] 2 NAPTHOIC ACID; ADENYLATE CYCLASE; CHEMOATTRACTANT; PURINERGIC P2Y RECEPTOR; PURINERGIC P2Y1 RECEPTOR; PURINERGIC P2Y11 RECEPTOR; PURINERGIC P2Y12 RECEPTOR; PURINERGIC P2Y13 RECEPTOR; PURINERGIC P2Y14 RECEPTOR; PURINERGIC P2Y2 RECEPTOR; PURINERGIC P2Y4 RECEPTOR; PURINERGIC P2Y6 RECEPTOR; UNCLASSIFIED DRUG; URIDINE DIPHOSPHATE GLUCOSE;

ARTICLE; CHEMOTAXIS; ENZYME INHIBITION; GLIOMA CELL; HUMAN; HUMAN CELL; MOLECULAR PROBE; MOLECULE; NEUTROPHIL; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA; PROTEIN EXPRESSION; RECEPTOR AFFINITY; SYNTHESIS;

ADENYLATE CYCLASE; ANIMALS; CELL LINE, TUMOR; CHEMOTAXIS; CHO CELLS; CRICETINAE; GLIOMA; HL-60 CELLS; HUMANS; LEUKEMIA, PROMYELOCYTIC, ACUTE; NEUTROPHILS; PURINERGIC P2 RECEPTOR AGONISTS; PURINERGIC P2 RECEPTOR ANTAGONISTS; RATS; RECEPTORS, PURINERGIC P2; URIDINE DIPHOSPHATE GLUCOSE;

EID: 84879124003     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.113.085654     Document Type: Article

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