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Volumn 12, Issue 3, 2013, Pages 377-389

Enhanced survival of wild-type and Lurcher purkinje cells in vitro following inhibition of conventional PKCs or stress-activated MAP kinase pathways

Author keywords

Cell death; JNK; Lurcher mutant mouse; MAP kinase; Organotypic culture; PKC; Purkinje cells

Indexed keywords

CALCIUM ION; CATION; GLUTAMATE RECEPTOR; JANUS KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE C; PROTEIN KINASE C GAMMA; STRESS ACTIVATED PROTEIN KINASE;

EID: 84879077840     PISSN: 14734222     EISSN: 14734230     Source Type: Journal    
DOI: 10.1007/s12311-012-0427-x     Document Type: Conference Paper
Times cited : (10)

References (48)
  • 1
    • 33847641082 scopus 로고    scopus 로고
    • The Lurcher mouse: Fresh insights from an old mutant
    • 16412991 10.1016/j.brainres.2005.11.086 1:CAS:528:DC%2BD2sXislWrs74%3D
    • Vogel MW, Caston J, Yuzaki M, Mariani J. The Lurcher mouse: fresh insights from an old mutant. Brain Res. 2007;1140:4-18.
    • (2007) Brain Res , vol.1140 , pp. 4-18
    • Vogel, M.W.1    Caston, J.2    Yuzaki, M.3    Mariani, J.4
  • 2
    • 0037194894 scopus 로고    scopus 로고
    • A novel protein complex linking the delta 2 glutamate receptor and autophagy: Implications for neurodegeneration in lurcher mice
    • 12372286 10.1016/S0896-6273(02)00861-9 1:CAS:528:DC%2BD38XntFSksrw%3D
    • Yue Z, Horton A, Bravin M, DeJager PL, Selimi F, Heintz N. A novel protein complex linking the delta 2 glutamate receptor and autophagy: implications for neurodegeneration in lurcher mice. Neuron. 2002;35(5):921-33.
    • (2002) Neuron , vol.35 , Issue.5 , pp. 921-933
    • Yue, Z.1    Horton, A.2    Bravin, M.3    Dejager, P.L.4    Selimi, F.5    Heintz, N.6
  • 3
    • 0037421996 scopus 로고    scopus 로고
    • Lurcher GRID2-induced death and depolarization can be dissociated in cerebellar Purkinje cells
    • 12628171 10.1016/S0896-6273(03)00093-X 1:CAS:528:DC%2BD3sXitlSrsLk%3D
    • Selimi F, Lohof AM, Heitz S, Lalouette A, Jarvis CI, Bailly Y, et al. Lurcher GRID2-induced death and depolarization can be dissociated in cerebellar Purkinje cells. Neuron. 2003;37(5):813-9.
    • (2003) Neuron , vol.37 , Issue.5 , pp. 813-819
    • Selimi, F.1    Lohof, A.M.2    Heitz, S.3    Lalouette, A.4    Jarvis, C.I.5    Bailly, Y.6
  • 4
    • 0026741025 scopus 로고
    • Early development of the Lurcher cerebellum: Purkinje cell alterations and impairment of synaptogenesis
    • 1500948 10.1007/BF01186954 1:STN:280:DyaK38zmsVKltQ%3D%3D
    • Dumesnil-Bousez N, Sotelo C. Early development of the Lurcher cerebellum: Purkinje cell alterations and impairment of synaptogenesis. J Neurocytol. 1992;21:506-29.
    • (1992) J Neurocytol , vol.21 , pp. 506-529
    • Dumesnil-Bousez, N.1    Sotelo, C.2
  • 5
    • 0028901215 scopus 로고
    • The lurcher gene induces apoptotic death in cerebellar Purkinje cells
    • 7743930 1:CAS:528:DyaK2MXltVamurg%3D
    • Norman DJ, Feng L, Cheng SS, Gubbay J, Chan E, Heintz N. The lurcher gene induces apoptotic death in cerebellar Purkinje cells. Development. 1995;121(4):1183-93.
    • (1995) Development , vol.121 , Issue.4 , pp. 1183-1193
    • Norman, D.J.1    Feng, L.2    Cheng, S.S.3    Gubbay, J.4    Chan, E.5    Heintz, N.6
  • 6
    • 0034143430 scopus 로고    scopus 로고
    • Target-related and intrinsic neuronal death in Lurcher mutant mice are both mediated by caspase-3 activation
    • 10648704 1:CAS:528:DC%2BD3cXhtFGqtL0%3D
    • Selimi F, Doughty M, Delhaye-Bouchaud N, Mariani J. Target-related and intrinsic neuronal death in Lurcher mutant mice are both mediated by caspase-3 activation. J Neurosci. 2000;20:992-1000.
    • (2000) J Neurosci , vol.20 , pp. 992-1000
    • Selimi, F.1    Doughty, M.2    Delhaye-Bouchaud, N.3    Mariani, J.4
  • 7
    • 0028783320 scopus 로고
    • Apoptotic cell death in the cerebellum of mutant weaver and lurcher mice
    • 8614556 10.1016/0304-3940(95)12090-Q 1:STN:280:DyaK287ptlSgtQ%3D%3D
    • Wullner U, Loschmann P-A, Weller M, Klockgether T. Apoptotic cell death in the cerebellum of mutant weaver and lurcher mice. Neurosci Lett. 1995;200:109-12.
    • (1995) Neurosci Lett , vol.200 , pp. 109-112
    • Wullner, U.1    Loschmann, P.-A.2    Weller, M.3    Klockgether, T.4
  • 8
    • 0030988604 scopus 로고    scopus 로고
    • Massive loss of mid- and hindbrain neurons during embryonic development of homozygous lurcher mice
    • 9065501 1:CAS:528:DyaK2sXitV2is74%3D
    • Cheng SS, Heintz N. Massive loss of mid- and hindbrain neurons during embryonic development of homozygous lurcher mice. J Neurosci. 1997;17(7):2400-7.
    • (1997) J Neurosci , vol.17 , Issue.7 , pp. 2400-2407
    • Cheng, S.S.1    Heintz, N.2
  • 9
    • 0034662343 scopus 로고    scopus 로고
    • Bax inactivation in Lurcher mutants rescues cerebellar granule cells but not Purkinje cells or inferior olivary neurons
    • 10884318 1:CAS:528:DC%2BD3cXlt1Wiuro%3D
    • Selimi F, Vogel MW, Mariani J. Bax inactivation in Lurcher mutants rescues cerebellar granule cells but not Purkinje cells or inferior olivary neurons. J Neurosci. 2000;20(14):5339-45.
    • (2000) J Neurosci , vol.20 , Issue.14 , pp. 5339-5345
    • Selimi, F.1    Vogel, M.W.2    Mariani, J.3
  • 10
    • 0034657953 scopus 로고    scopus 로고
    • Neurodegeneration in Lurcher mice occurs via multiple cell death pathways
    • 10804210 1:CAS:528:DC%2BD3cXjtlKqsLw%3D
    • Doughty ML, De Jager PL, Korsmeyer SJ, Heintz N. Neurodegeneration in Lurcher mice occurs via multiple cell death pathways. J Neurosci. 2000;20(10):3687-94.
    • (2000) J Neurosci , vol.20 , Issue.10 , pp. 3687-3694
    • Doughty, M.L.1    De Jager, P.L.2    Korsmeyer, S.J.3    Heintz, N.4
  • 11
    • 34548309062 scopus 로고    scopus 로고
    • Oxidative stress, nitric oxide, and the mechanisms of cell death in Lurcher Purkinje cells
    • 10.1002/dneu.20391 1:CAS:528:DC%2BD2sXosF2jtrc%3D
    • McFarland R, Blokhin A, Sydnor J, Mariani J, Vogel MW. Oxidative stress, nitric oxide, and the mechanisms of cell death in Lurcher Purkinje cells. Devel Neurobio. 2007;67:1032-46.
    • (2007) Devel Neurobio. , vol.67 , pp. 1032-1046
    • McFarland, R.1    Blokhin, A.2    Sydnor, J.3    Mariani, J.4    Vogel, M.W.5
  • 12
    • 77955916237 scopus 로고    scopus 로고
    • Redox control of protein kinase C: Cell- and disease-specific aspects
    • 20136499 10.1089/ars.2009.2825 1:CAS:528:DC%2BC3cXhtVCksb7L
    • Giorgi C, Agnoletto C, Baldini C, Bononi A, Bonora M, Marchi S, et al. Redox control of protein kinase C: cell- and disease-specific aspects. Antioxid Redox Signal. 2010;13(7):1051-85.
    • (2010) Antioxid Redox Signal , vol.13 , Issue.7 , pp. 1051-1085
    • Giorgi, C.1    Agnoletto, C.2    Baldini, C.3    Bononi, A.4    Bonora, M.5    Marchi, S.6
  • 13
    • 41549160315 scopus 로고    scopus 로고
    • Phosphatase-mediated crosstalk between MAPK signaling pathways in the regulation of cell survival
    • 18039929 10.1096/fj.06-7859rev 1:CAS:528:DC%2BD1cXktlWnsLs%3D
    • Junttila MR, Li SP, Westermarck J. Phosphatase-mediated crosstalk between MAPK signaling pathways in the regulation of cell survival. FASEB J. 2008;22(4):954-65.
    • (2008) FASEB J , vol.22 , Issue.4 , pp. 954-965
    • Junttila, M.R.1    Li, S.P.2    Westermarck, J.3
  • 14
    • 33644862368 scopus 로고    scopus 로고
    • JNK signaling pathway is a key modulator in cell death mediated by reactive oxygen and nitrogen species
    • 16540388 10.1016/j.freeradbiomed.2005.10.056 1:CAS:528: DC%2BD28Xis1egtL4%3D Epub 2005 Nov 21
    • Shen HM, Liu ZG. JNK signaling pathway is a key modulator in cell death mediated by reactive oxygen and nitrogen species. Free Radic Biol Med. 2006;40(6):928-39. Epub 2005 Nov 21.
    • (2006) Free Radic Biol Med , vol.40 , Issue.6 , pp. 928-939
    • Shen, H.M.1    Liu, Z.G.2
  • 15
    • 0030800468 scopus 로고    scopus 로고
    • Neurodegeneration in Lurcher mice caused by mutation in δ2 glutamate receptor
    • 9285588 10.1038/42009 1:CAS:528:DyaK2sXls1Gru7c%3D
    • Zuo J, De Jager PL, Takahashi KA, Jiang W, Linden DJ, Heintz N. Neurodegeneration in Lurcher mice caused by mutation in δ2 glutamate receptor. Nature. 1997;388:769-73.
    • (1997) Nature , vol.388 , pp. 769-773
    • Zuo, J.1    De Jager, P.L.2    Takahashi, K.A.3    Jiang, W.4    Linden, D.J.5    Heintz, N.6
  • 16
    • 34249015705 scopus 로고    scopus 로고
    • Reinnervation of late post-natal Purkinje cells by climbing fibres: Neosynaptogenesis without transient multi-innervation
    • 17507559 10.1523/JNEUROSCI.0452-07.2007 1:CAS:528:DC%2BD2sXlvFGhsro%3D
    • Letellier M, Demais V, Bailly Y, Sherrard RM, Mariani J, Lohof AM. Reinnervation of late post-natal Purkinje cells by climbing fibres: neosynaptogenesis without transient multi-innervation. J Neurosci. 2007;27:5373-83.
    • (2007) J Neurosci , vol.27 , pp. 5373-5383
    • Letellier, M.1    Demais, V.2    Bailly, Y.3    Sherrard, R.M.4    Mariani, J.5    Lohof, A.M.6
  • 17
    • 85047694376 scopus 로고    scopus 로고
    • Protein kinase C: Its role in activity-dependent Purkinje cell dendritic development and plasticity
    • 14509570 10.1080/14734220310016150 1:CAS:528:DC%2BD3sXotVOnt7k%3D
    • Metzger F, Kapfhammer JP. Protein kinase C: its role in activity-dependent Purkinje cell dendritic development and plasticity. Cerebellum. 2003;2(3):206-14.
    • (2003) Cerebellum , vol.2 , Issue.3 , pp. 206-214
    • Metzger, F.1    Kapfhammer, J.P.2
  • 19
    • 58149086969 scopus 로고    scopus 로고
    • Specific JNK inhibition by D-JNKI1 protects Purkinje cells from cell death in Lurcher mutant mouse
    • 18949529 10.1007/s12311-008-0070-8 1:CAS:528:DC%2BD1cXhsFSrurvO
    • Repici M, Zanjani HS, Gautheron V, Borsello T, Dusart I, Mariani J. Specific JNK inhibition by D-JNKI1 protects Purkinje cells from cell death in Lurcher mutant mouse. Cerebellum. 2008;7(4):534-8.
    • (2008) Cerebellum , vol.7 , Issue.4 , pp. 534-538
    • Repici, M.1    Zanjani, H.S.2    Gautheron, V.3    Borsello, T.4    Dusart, I.5    Mariani, J.6
  • 20
    • 0036336853 scopus 로고    scopus 로고
    • Partial rescue of neural apoptosis in the Lurcher mutant mouse through elimination of tissue plasminogen activator
    • 11934869 1:CAS:528:DC%2BD38XjslSls7Y%3D
    • Lu W, Tsirka SE. Partial rescue of neural apoptosis in the Lurcher mutant mouse through elimination of tissue plasminogen activator. Development. 2002;129(8):2043-50.
    • (2002) Development , vol.129 , Issue.8 , pp. 2043-2050
    • Lu, W.1    Tsirka, S.E.2
  • 21
    • 80455162610 scopus 로고    scopus 로고
    • Mechanisms of compartmental Purkinje cell death and survival in the Lurcher mutant mouse
    • 10.1007/s12311-010-0231-4
    • Armstrong CL, Duffin CA, McFarland R, Vogel MW. Mechanisms of compartmental Purkinje cell death and survival in the Lurcher mutant mouse. Cerebellum. 2010;10(3):504-14.
    • (2010) Cerebellum , vol.10 , Issue.3 , pp. 504-514
    • Armstrong, C.L.1    Duffin, C.A.2    McFarland, R.3    Vogel, M.W.4
  • 22
    • 77952153512 scopus 로고    scopus 로고
    • Heat shock protein 25 expression and preferential Purkinje cell survival in the Lurcher mutant mouse cerebellum
    • 20394049 10.1002/cne.22309 1:CAS:528:DC%2BC3cXmslCnur4%3D
    • Duffin CA, McFarland R, Sarna JR, Vogel MW, Armstrong CL. Heat shock protein 25 expression and preferential Purkinje cell survival in the Lurcher mutant mouse cerebellum. J Comp Neurol. 2010;518:1892-907.
    • (2010) J Comp Neurol , vol.518 , pp. 1892-1907
    • Duffin, C.A.1    McFarland, R.2    Sarna, J.R.3    Vogel, M.W.4    Armstrong, C.L.5
  • 23
    • 0033811985 scopus 로고    scopus 로고
    • Implication of Bcl-2 and caspase-3 in age-related Purkinje cell death in murine organotypic culture: An in vitro model to study apoptosis
    • 10971635 10.1046/j.1460-9568.2000.00186.x 1:STN:280: DC%2BD3cvptlantg%3D%3D
    • Ghoumari AM, Wehrle R, Bernard O, Sotelo C, Dusart I. Implication of Bcl-2 and caspase-3 in age-related Purkinje cell death in murine organotypic culture: an in vitro model to study apoptosis. Eur J Neurosci. 2000;12(8):2935-49.
    • (2000) Eur J Neurosci , vol.12 , Issue.8 , pp. 2935-2949
    • Ghoumari, A.M.1    Wehrle, R.2    Bernard, O.3    Sotelo, C.4    Dusart, I.5
  • 24
    • 0036580678 scopus 로고    scopus 로고
    • Inhibition of protein kinase C prevents Purkinje cell death but does not affect axonal regeneration
    • 11978830 1:CAS:528:DC%2BD38Xjs1Sgs70%3D
    • Ghoumari AM, Wehrle R, De Zeeuw CI, Sotelo C, Dusart I. Inhibition of protein kinase C prevents Purkinje cell death but does not affect axonal regeneration. J Neurosci. 2002;22(9):3531-42.
    • (2002) J Neurosci , vol.22 , Issue.9 , pp. 3531-3542
    • Ghoumari, A.M.1    Wehrle, R.2    De Zeeuw, C.I.3    Sotelo, C.4    Dusart, I.5
  • 25
    • 0037596472 scopus 로고    scopus 로고
    • Mifepristone (RU486) protects Purkinje cells from cell death in organotypic slice cultures of postnatal rat and mouse cerebellum
    • 12810951 10.1073/pnas.1332667100 1:CAS:528:DC%2BD3sXlt1Wqt70%3D
    • Ghoumari AM, Dusart I, El-Etr M, Tronche F, Sotelo C, Schumacher M, et al. Mifepristone (RU486) protects Purkinje cells from cell death in organotypic slice cultures of postnatal rat and mouse cerebellum. Proc Natl Acad Sci U S A. 2003;100(13):7953-8.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , Issue.13 , pp. 7953-7958
    • Ghoumari, A.M.1    Dusart, I.2    El-Etr, M.3    Tronche, F.4    Sotelo, C.5    Schumacher, M.6
  • 26
    • 80051784346 scopus 로고    scopus 로고
    • C-Jun N-terminal kinase (JNK) and p38 play different roles in age-related Purkinje cell death in murine organotypic culture
    • 10.1007/s12311-010-0244-z
    • Repici M, Wehrle R, Antoniou X, Borsello T, Dusart I. c-Jun N-terminal kinase (JNK) and p38 play different roles in age-related Purkinje cell death in murine organotypic culture. Cerebellum. 2010;10(2):281-90.
    • (2010) Cerebellum , vol.10 , Issue.2 , pp. 281-290
    • Repici, M.1    Wehrle, R.2    Antoniou, X.3    Borsello, T.4    Dusart, I.5
  • 27
    • 1942447829 scopus 로고    scopus 로고
    • Microglia promote the death of developing Purkinje cells
    • 14980203 10.1016/S0896-6273(04)00069-8 1:CAS:528:DC%2BD2cXhvFOrsLs%3D
    • Marin-Teva JL, Dusart I, Colin C, Gervais A, van Rooijen N, Mallat M. Microglia promote the death of developing Purkinje cells. Neuron. 2004;41(4):535-47.
    • (2004) Neuron , vol.41 , Issue.4 , pp. 535-547
    • Marin-Teva, J.L.1    Dusart, I.2    Colin, C.3    Gervais, A.4    Van Rooijen, N.5    Mallat, M.6
  • 28
    • 0035923665 scopus 로고    scopus 로고
    • SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase
    • 11717429 10.1073/pnas.251194298 1:CAS:528:DC%2BD3MXovVynsbg%3D
    • Bennett BL, Sasaki DT, Murray BW, O'Leary EC, Sakata ST, Xu W, et al. SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase. Proc Natl Acad Sci U S A. 2001;98(24):13681-6.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , Issue.24 , pp. 13681-13686
    • Bennett, B.L.1    Sasaki, D.T.2    Murray, B.W.3    O'Leary, E.C.4    Sakata, S.T.5    Xu, W.6
  • 29
    • 36549040859 scopus 로고    scopus 로고
    • The selectivity of protein kinase inhibitors: A further update
    • 17850214 10.1042/BJ20070797 1:CAS:528:DC%2BD2sXhtlGmtbjE
    • Bain J, Plater L, Elliott M, Shpiro N, Hastie CJ, McLauchlan H, et al. The selectivity of protein kinase inhibitors: a further update. Biochem J. 2007;408(3):297-315.
    • (2007) Biochem J , vol.408 , Issue.3 , pp. 297-315
    • Bain, J.1    Plater, L.2    Elliott, M.3    Shpiro, N.4    Hastie, C.J.5    McLauchlan, H.6
  • 30
    • 0027157640 scopus 로고
    • Selective inhibition of protein kinase C isozymes by the indolocarbazole Go 6976
    • 8486620 1:CAS:528:DyaK3sXkvV2ktrs%3D
    • Martiny-Baron G, Kazanietz MG, Mischak H, Blumberg PM, Kochs G, Hug H, et al. Selective inhibition of protein kinase C isozymes by the indolocarbazole Go 6976. J Biol Chem. 1993;268(13):9194-7.
    • (1993) J Biol Chem , vol.268 , Issue.13 , pp. 9194-9197
    • Martiny-Baron, G.1    Kazanietz, M.G.2    Mischak, H.3    Blumberg, P.M.4    Kochs, G.5    Hug, H.6
  • 31
    • 33644685637 scopus 로고    scopus 로고
    • The role of protein kinase C in cerebral ischemic and reperfusion injury
    • 16254221 10.1161/01.STR.0000189996.71237.f7 1:CAS:528:DC%2BD2MXht1arsLnM Epub 2005 Oct 27
    • Bright R, Mochly-Rosen D. The role of protein kinase C in cerebral ischemic and reperfusion injury. Stroke. 2005;36(12):2781-90. Epub 2005 Oct 27.
    • (2005) Stroke , vol.36 , Issue.12 , pp. 2781-2790
    • Bright, R.1    Mochly-Rosen, D.2
  • 32
    • 0032588967 scopus 로고    scopus 로고
    • Go 6976 is a potent inhibitor of neurotrophin-receptor intrinsic tyrosine kinase
    • 10037462 10.1046/j.1471-4159.1999.0720919.x 1:CAS:528:DyaK1MXhsFWgsr4%3D
    • Behrens MM, Strasser U, Choi DW. Go 6976 is a potent inhibitor of neurotrophin-receptor intrinsic tyrosine kinase. J Neurochem. 1999;72(3):919-24.
    • (1999) J Neurochem , vol.72 , Issue.3 , pp. 919-924
    • Behrens, M.M.1    Strasser, U.2    Choi, D.W.3
  • 33
    • 0032031999 scopus 로고    scopus 로고
    • Expression of a protein kinase C inhibitor in Purkinje cells blocks cerebellar LTD and adaptation of the vestibulo-ocular reflex
    • 9539124 10.1016/S0896-6273(00)80990-3
    • De Zeeuw CI, Hansel C, Bian F, Koekkoek SK, van Alphen AM, Linden DJ, et al. Expression of a protein kinase C inhibitor in Purkinje cells blocks cerebellar LTD and adaptation of the vestibulo-ocular reflex. Neuron. 1998;20(3):495-508.
    • (1998) Neuron , vol.20 , Issue.3 , pp. 495-508
    • De Zeeuw, C.I.1    Hansel, C.2    Bian, F.3    Koekkoek, S.K.4    Van Alphen, A.M.5    Linden, D.J.6
  • 34
    • 0035976957 scopus 로고    scopus 로고
    • Phospholipase Cbeta4 and protein kinase Calpha and/or protein kinase CbetaI are involved in the induction of long term depression in cerebellar Purkinje cells
    • 11551922 10.1074/jbc.M105413200 1:CAS:528:DC%2BD3MXovFensb8%3D
    • Hirono M, Sugiyama T, Kishimoto Y, Sakai I, Miyazawa T, Kishio M, et al. Phospholipase Cbeta4 and protein kinase Calpha and/or protein kinase CbetaI are involved in the induction of long term depression in cerebellar Purkinje cells. J Biol Chem. 2001;276(48):45236-42.
    • (2001) J Biol Chem , vol.276 , Issue.48 , pp. 45236-45242
    • Hirono, M.1    Sugiyama, T.2    Kishimoto, Y.3    Sakai, I.4    Miyazawa, T.5    Kishio, M.6
  • 35
    • 0034676110 scopus 로고    scopus 로고
    • Distribution of protein kinase Mzeta and the complete protein kinase C isoform family in rat brain
    • 10982466 10.1002/1096-9861(20001016)426:2<243: AID-CNE6>3.0.CO;2-8 1:CAS:528:DC%2BD3cXnsVKjtLs%3D
    • Naik MU, Benedikz E, Hernandez I, Libien J, Hrabe J, Valsamis M, et al. Distribution of protein kinase Mzeta and the complete protein kinase C isoform family in rat brain. J Comp Neurol. 2000;426(2):243-58.
    • (2000) J Comp Neurol , vol.426 , Issue.2 , pp. 243-258
    • Naik, M.U.1    Benedikz, E.2    Hernandez, I.3    Libien, J.4    Hrabe, J.5    Valsamis, M.6
  • 36
    • 8844236296 scopus 로고    scopus 로고
    • A unique PDZ ligand in PKCalpha confers induction of cerebellar long-term synaptic depression
    • 15541307 10.1016/j.neuron.2004.10.024 1:CAS:528:DC%2BD2cXhtVKhurjJ
    • Leitges M, Kovac J, Plomann M, Linden DJ. A unique PDZ ligand in PKCalpha confers induction of cerebellar long-term synaptic depression. Neuron. 2004;44(4):585-94.
    • (2004) Neuron , vol.44 , Issue.4 , pp. 585-594
    • Leitges, M.1    Kovac, J.2    Plomann, M.3    Linden, D.J.4
  • 37
    • 0034090001 scopus 로고    scopus 로고
    • Protein kinase C activity modulates dendritic differentiation of rat Purkinje cells in cerebellar slice cultures
    • 10886339 10.1046/j.1460-9568.2000.00086.x 1:STN:280: DC%2BD3czpt1Srsw%3D%3D
    • Metzger F, Kapfhammer JP. Protein kinase C activity modulates dendritic differentiation of rat Purkinje cells in cerebellar slice cultures. Eur J Neurosci. 2000;12(6):1993-2005.
    • (2000) Eur J Neurosci , vol.12 , Issue.6 , pp. 1993-2005
    • Metzger, F.1    Kapfhammer, J.P.2
  • 38
    • 0029591742 scopus 로고
    • Impaired synapse elimination during cerebellar development in PKC gamma mutant mice
    • 8548808 10.1016/0092-8674(95)90147-7 1:CAS:528:DyaK28XhsVOmsg%3D%3D
    • Kano M, Hashimoto K, Chen C, Abeliovich A, Aiba A, Kurihara H, et al. Impaired synapse elimination during cerebellar development in PKC gamma mutant mice. Cell. 1995;83:1223-31.
    • (1995) Cell , vol.83 , pp. 1223-1231
    • Kano, M.1    Hashimoto, K.2    Chen, C.3    Abeliovich, A.4    Aiba, A.5    Kurihara, H.6
  • 39
    • 0037012451 scopus 로고    scopus 로고
    • Altered dendritic development of cerebellar Purkinje cells in slice cultures from protein kinase Cgamma-deficient mice
    • 11934475 10.1016/S0306-4522(01)00559-0 1:CAS:528:DC%2BD38XisV2hsrg%3D
    • Schrenk K, Kapfhammer JP, Metzger F. Altered dendritic development of cerebellar Purkinje cells in slice cultures from protein kinase Cgamma-deficient mice. Neuroscience. 2002;110(4):675-89.
    • (2002) Neuroscience , vol.110 , Issue.4 , pp. 675-689
    • Schrenk, K.1    Kapfhammer, J.P.2    Metzger, F.3
  • 40
    • 33846528583 scopus 로고    scopus 로고
    • PKC signaling deficits: A mechanistic hypothesis for the origins of Alzheimer's disease
    • 17218018 10.1016/j.tips.2006.12.002 1:CAS:528:DC%2BD2sXhtlCmu7o%3D
    • Alkon DL, Sun MK, Nelson TJ. PKC signaling deficits: a mechanistic hypothesis for the origins of Alzheimer's disease. Trends Pharmacol Sci. 2007;28(2):51-60.
    • (2007) Trends Pharmacol Sci , vol.28 , Issue.2 , pp. 51-60
    • Alkon, D.L.1    Sun, M.K.2    Nelson, T.J.3
  • 41
    • 36749025313 scopus 로고    scopus 로고
    • Protein kinase Cdelta and apoptosis
    • 17956263 10.1042/BST0351001 1:CAS:528:DC%2BD2sXht1eru7%2FJ
    • Reyland ME. Protein kinase Cdelta and apoptosis. Biochem Soc Trans. 2007;35:1001-4.
    • (2007) Biochem Soc Trans , vol.35 , pp. 1001-1004
    • Reyland, M.E.1
  • 42
    • 55949109631 scopus 로고    scopus 로고
    • Structural basis of protein kinase C isoform function
    • 18923184 10.1152/physrev.00034.2007 1:CAS:528:DC%2BD1cXhtlGgtbnJ
    • Steinberg SF. Structural basis of protein kinase C isoform function. Physiol Rev. 2008;88(4):1341-78.
    • (2008) Physiol Rev , vol.88 , Issue.4 , pp. 1341-1378
    • Steinberg, S.F.1
  • 43
    • 17144369501 scopus 로고    scopus 로고
    • Oxidative activation of protein kinase Cgamma through the C1 domain. Effects on gap junctions
    • 15642736 10.1074/jbc.M407762200 1:CAS:528:DC%2BD2MXivV2ktb4%3D
    • Lin D, Takemoto DJ. Oxidative activation of protein kinase Cgamma through the C1 domain. Effects on gap junctions. J Biol Chem. 2005;280(14):13682-93.
    • (2005) J Biol Chem , vol.280 , Issue.14 , pp. 13682-13693
    • Lin, D.1    Takemoto, D.J.2
  • 44
    • 0034816642 scopus 로고    scopus 로고
    • Peroxynitrite-induced tyrosine nitration and inhibition of protein kinase C
    • 11520063 10.1006/bbrc.2001.5448 1:CAS:528:DC%2BD3MXmtFyqsr4%3D
    • Knapp LT, Kanterewicz BI, Hayes EL, Klann E. Peroxynitrite-induced tyrosine nitration and inhibition of protein kinase C. Biochem Biophys Res Commun. 2001;286(4):764-70.
    • (2001) Biochem Biophys Res Commun , vol.286 , Issue.4 , pp. 764-770
    • Knapp, L.T.1    Kanterewicz, B.I.2    Hayes, E.L.3    Klann, E.4
  • 45
    • 16344395930 scopus 로고    scopus 로고
    • Proteolytic activation of protein kinase Calpha by peroxynitrite in stimulating cytosolic phospholipase A2 in pulmonary endothelium: Involvement of a pertussis toxin sensitive protein
    • 15794661 10.1021/bi0477889 1:CAS:528:DC%2BD2MXit1ahu7w%3D
    • Chakraborti T, Das S, Chakraborti S. Proteolytic activation of protein kinase Calpha by peroxynitrite in stimulating cytosolic phospholipase A2 in pulmonary endothelium: involvement of a pertussis toxin sensitive protein. Biochemistry. 2005;44(13):5246-57.
    • (2005) Biochemistry , vol.44 , Issue.13 , pp. 5246-5257
    • Chakraborti, T.1    Das, S.2    Chakraborti, S.3
  • 46
    • 76649135454 scopus 로고    scopus 로고
    • Reevaluation of neurodegeneration in lurcher mice: Constitutive ion fluxes cause cell death with, not by, autophagy
    • 20147545 10.1523/JNEUROSCI.6030-09.2010 1:CAS:528:DC%2BC3cXkt12ltbc%3D
    • Nishiyama J, Matsuda K, Kakegawa W, Yamada N, Motohashi J, Mizushima N, et al. Reevaluation of neurodegeneration in lurcher mice: constitutive ion fluxes cause cell death with, not by, autophagy. J Neurosci. 2010;30(6):2177-87.
    • (2010) J Neurosci , vol.30 , Issue.6 , pp. 2177-2187
    • Nishiyama, J.1    Matsuda, K.2    Kakegawa, W.3    Yamada, N.4    Motohashi, J.5    Mizushima, N.6
  • 47
    • 77956012154 scopus 로고    scopus 로고
    • Nitric oxide and neuronal death
    • 20547235 10.1016/j.niox.2010.06.001 1:CAS:528:DC%2BC3cXhtVKgsrnP
    • Brown GC. Nitric oxide and neuronal death. Nitric Oxide. 2010;23(3):153-65.
    • (2010) Nitric Oxide , vol.23 , Issue.3 , pp. 153-165
    • Brown, G.C.1
  • 48
    • 0032144869 scopus 로고    scopus 로고
    • Overexpression of a Hu-bcl-2 transgene in Lurcher mutant mice delays Purkinje cell death
    • 9769861 10.1016/S0764-4469(98)80002-4 1:CAS:528:DyaK1MXmvV2ku78%3D
    • Zanjani H, Rondi-Reig L, Vogel M, Martinou JC, Delhaye-Bouchaud N, Mariani J. Overexpression of a Hu-bcl-2 transgene in Lurcher mutant mice delays Purkinje cell death. C R Acad Sci III. 1998;321(8):633-40.
    • (1998) C R Acad Sci III , vol.321 , Issue.8 , pp. 633-640
    • Zanjani, H.1    Rondi-Reig, L.2    Vogel, M.3    Martinou, J.C.4    Delhaye-Bouchaud, N.5    Mariani, J.6


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