메뉴 건너뛰기




Volumn 20, Issue 14, 2000, Pages 5339-5345

Bax inactivation in Lurcher mutants rescues cerebellar granule cells but not Purkinje cells or inferior olivary neurons

Author keywords

Bax; Granule cell; Inferior olive; Lurcher; Neuronal death; Purkinje cell

Indexed keywords

GLUTAMATE RECEPTOR; PROTEIN BAX;

EID: 0034662343     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.20-14-05339.2000     Document Type: Article
Times cited : (58)

References (49)
  • 1
    • 0032575688 scopus 로고    scopus 로고
    • The bcl-2 protein family: Arbiters of cell survival
    • Adams JM, Cory S (1998) The bcl-2 protein family: arbiters of cell survival. Science 281:1322-1326.
    • (1998) Science , vol.281 , pp. 1322-1326
    • Adams, J.M.1    Cory, S.2
  • 2
    • 0027243086 scopus 로고
    • The protooncogene bcl-2 can selectively rescue neurotrophic factor-dependent neurons from apoptosis
    • Allsopp TE, Wyatt S, Paterson HF, Davies AM (1993) The protooncogene bcl-2 can selectively rescue neurotrophic factor-dependent neurons from apoptosis. Cell 73:295-307.
    • (1993) Cell , vol.73 , pp. 295-307
    • Allsopp, T.E.1    Wyatt, S.2    Paterson, H.F.3    Davies, A.M.4
  • 4
    • 0027427493 scopus 로고
    • Bcl-2 affects survival but not neuronal differentiation of PC12 cells
    • Batistatou A, Merry DE, Korsmeyer SJ, Greene LA (1993) Bcl-2 affects survival but not neuronal differentiation of PC12 cells. J Neurosci 13:4422-4428.
    • (1993) J Neurosci , vol.13 , pp. 4422-4428
    • Batistatou, A.1    Merry, D.E.2    Korsmeyer, S.J.3    Greene, L.A.4
  • 5
    • 0030008918 scopus 로고    scopus 로고
    • Protection of retinal ganglion cells from natural and axotomy-induced cell death in neonatal transgenic mice overexpressing bcl-2
    • Bonfanti L, Strettoi E, Chierzi S, Cenni MC, Liu X-H, Martinou J-C, Maffei L, Rabacchi SA (1996) Protection of retinal ganglion cells from natural and axotomy-induced cell death in neonatal transgenic mice overexpressing bcl-2. J Neurosci 16:4186-4194.
    • (1996) J Neurosci , vol.16 , pp. 4186-4194
    • Bonfanti, L.1    Strettoi, E.2    Chierzi, S.3    Cenni, M.C.4    Liu, X.-H.5    Martinou, J.-C.6    Maffei, L.7    Rabacchi, S.A.8
  • 6
    • 0018788266 scopus 로고
    • Structural and quantitative studies on the normal C3H and Lurcher mutant mouse
    • Caddy KWT, Biscoe TJ (1979) Structural and quantitative studies on the normal C3H and Lurcher mutant mouse. Phil Trans R Soc Lond B Biol Sci 287:167-201.
    • (1979) Phil Trans R Soc Lond B Biol Sci , vol.287 , pp. 167-201
    • Caddy, K.W.T.1    Biscoe, T.J.2
  • 7
    • 0342295188 scopus 로고
    • An early critical period in olivocerebellar interactions defined by targeted ablation of Purkinje cells
    • Chu T, Oberdick J (1995) An early critical period in olivocerebellar interactions defined by targeted ablation of Purkinje cells. Soc Neurosci Abstr 21:916.
    • (1995) Soc Neurosci Abstr , vol.21 , pp. 916
    • Chu, T.1    Oberdick, J.2
  • 8
    • 0029962130 scopus 로고    scopus 로고
    • Time course of axotomy-induced apoptotic cell death in facial motoneurons of neonatal wild type and bcl-2 transgenic mice
    • De Bilbao F, Dubois-Dauphin M (1996) Time course of axotomy-induced apoptotic cell death in facial motoneurons of neonatal wild type and bcl-2 transgenic mice. Neuroscience 71:1111-1119.
    • (1996) Neuroscience , vol.71 , pp. 1111-1119
    • De Bilbao, F.1    Dubois-Dauphin, M.2
  • 9
    • 0033526922 scopus 로고    scopus 로고
    • Postnatal distribution of cpp32/caspase 3 mRNA in the mouse central nervous system: An in situ hybridization study
    • De Bilbao F, Guarin E, Nef P, Vallet P, Giannakopoulos P, Dubois-Dauphin M (1999) Postnatal distribution of cpp32/caspase 3 mRNA in the mouse central nervous system: an in situ hybridization study. J Comp Neurol 409:339-357.
    • (1999) J Comp Neurol , vol.409 , pp. 339-357
    • De Bilbao, F.1    Guarin, E.2    Nef, P.3    Vallet, P.4    Giannakopoulos, P.5    Dubois-Dauphin, M.6
  • 10
    • 0031690033 scopus 로고    scopus 로고
    • The lurcher mutation and ionotropic glutamate receptors: Contributions to programmed neuronal death in vivo
    • De Jager PL, Heintz N (1998) The lurcher mutation and ionotropic glutamate receptors: contributions to programmed neuronal death in vivo. Brain Pathol 8:795-807.
    • (1998) Brain Pathol , vol.8 , pp. 795-807
    • De Jager, P.L.1    Heintz, N.2
  • 12
    • 0033134940 scopus 로고    scopus 로고
    • Afferent-target cell interactions in the cerebellum: Negative effect of granule cells on Purkinje cell development in Lurcher mice
    • Doughty ML, Lohof A, Selimi F, Delhaye-Bouchaud N, Mariani J (1999) Afferent-target cell interactions in the cerebellum: negative effect of granule cells on Purkinje cell development in Lurcher mice. J Neurosci 19:3448-3456.
    • (1999) J Neurosci , vol.19 , pp. 3448-3456
    • Doughty, M.L.1    Lohof, A.2    Selimi, F.3    Delhaye-Bouchaud, N.4    Mariani, J.5
  • 13
    • 0028343507 scopus 로고
    • Neonatal motoneurons overexpressing the bcl-2 protooncogene in transgenic mice are protected from axotomy-induced cell death
    • Dubois-Dauphin M, Frankowski H, Tsujimoto Y, Huarte J, Martinou J-C (1994) Neonatal motoneurons overexpressing the bcl-2 protooncogene in transgenic mice are protected from axotomy-induced cell death. Proc Natl Acad Sci USA 91:3309-3313.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 3309-3313
    • Dubois-Dauphin, M.1    Frankowski, H.2    Tsujimoto, Y.3    Huarte, J.4    Martinou, J.-C.5
  • 14
    • 0026741025 scopus 로고
    • Early development of the Lurcher cerebellum: Purkinje cell alterations and impairment of synaptogenesis
    • Dumesnil-Bousez N, Sotelo C (1992) Early development of the Lurcher cerebellum: Purkinje cell alterations and impairment of synaptogenesis. J Neurocytol 21:506-529.
    • (1992) J Neurocytol , vol.21 , pp. 506-529
    • Dumesnil-Bousez, N.1    Sotelo, C.2
  • 15
    • 0029047946 scopus 로고
    • bcl-2 transgene expression can protect neurons against developmental and induced cell death
    • Farlie PG, Dringen R, Rees SM, Kannourakis G, Bernard O (1995) bcl-2 transgene expression can protect neurons against developmental and induced cell death. Proc Natl Acad Sci USA 92:4397-4401.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 4397-4401
    • Farlie, P.G.1    Dringen, R.2    Rees, S.M.3    Kannourakis, G.4    Bernard, O.5
  • 16
    • 0026454763 scopus 로고
    • Prevention of programmed cell death of sympathetic neurons by the bcl-2 protooncogene
    • Garcia I, Martinou I, Tsujimoto Y, Martinou JC (1992) Prevention of programmed cell death of sympathetic neurons by the bcl-2 protooncogene. Science 258:302-304.
    • (1992) Science , vol.258 , pp. 302-304
    • Garcia, I.1    Martinou, I.2    Tsujimoto, Y.3    Martinou, J.C.4
  • 17
    • 0033179760 scopus 로고    scopus 로고
    • BCL-2 family members and the mitochondria in apoptosis
    • Gross A, McDonnell JM, Korsmeyer SJ (1999) BCL-2 family members and the mitochondria in apoptosis. Genes Dev 13:1899-1911.
    • (1999) Genes Dev , vol.13 , pp. 1899-1911
    • Gross, A.1    McDonnell, J.M.2    Korsmeyer, S.J.3
  • 18
    • 84981841011 scopus 로고
    • The influence of the cerebellum on development and maintenance of the inferior olive and the pons
    • Harkmark W (1956) The influence of the cerebellum on development and maintenance of the inferior olive and the pons. J Exp Zool 131:333-372.
    • (1956) J Exp Zool , vol.131 , pp. 333-372
    • Harkmark, W.1
  • 19
    • 0025938766 scopus 로고
    • Olivary morphology and olivocerebellar topography in adult lurcher mutant mice
    • Heckroth JA, Eisenman LM (1991) Olivary morphology and olivocerebellar topography in adult lurcher mutant mice. J Comp Neurol 312:541-651.
    • (1991) J Comp Neurol , vol.312 , pp. 541-651
    • Heckroth, J.A.1    Eisenman, L.M.2
  • 20
    • 0017083859 scopus 로고
    • A method to correct adequately for the change in neuronal size when estimating neuronal numbers after nerve growth factor treatment
    • Hendry IA (1976) A method to correct adequately for the change in neuronal size when estimating neuronal numbers after nerve growth factor treatment. J Neurocytol 5:337-349.
    • (1976) J Neurocytol , vol.5 , pp. 337-349
    • Hendry, I.A.1
  • 21
    • 0030599431 scopus 로고    scopus 로고
    • The numerical matching of source and target populations in the CNS: The inferior olive to Purkinje cell projection
    • Herrup K, Shojaeian-Zanjani H, Panzini L, Sunter K, Mariani J (1996) The numerical matching of source and target populations in the CNS: the inferior olive to Purkinje cell projection. Dev Brain Res 96:28-35.
    • (1996) Dev Brain Res , vol.96 , pp. 28-35
    • Herrup, K.1    Shojaeian-Zanjani, H.2    Panzini, L.3    Sunter, K.4    Mariani, J.5
  • 23
    • 0030907924 scopus 로고    scopus 로고
    • Signal transduction by the neurotrophin receptors
    • Kaplan DR, Miller FD (1997) Signal transduction by the neurotrophin receptors. Curr Opin Cell Biol 9:213-221.
    • (1997) Curr Opin Cell Biol , vol.9 , pp. 213-221
    • Kaplan, D.R.1    Miller, F.D.2
  • 25
    • 0032532213 scopus 로고    scopus 로고
    • Modulation of endoplasmic reticulum calcium pump by Bcl-2
    • Kuo TH, Kim HR, Zhu L, Yu Y, Lin HM, Tsang W (1998) Modulation of endoplasmic reticulum calcium pump by Bcl-2. Oncogene 17:1903-1910.
    • (1998) Oncogene , vol.17 , pp. 1903-1910
    • Kuo, T.H.1    Kim, H.R.2    Zhu, L.3    Yu, Y.4    Lin, H.M.5    Tsang, W.6
  • 26
    • 0031865351 scopus 로고    scopus 로고
    • Bcl-2 and Bax interactions in mitochondria probed with green fluorescent protein and fluorescence resonance energy transfer
    • Mahajan (1998) Bcl-2 and Bax interactions in mitochondria probed with green fluorescent protein and fluorescence resonance energy transfer. Nat Biotech 16:547-552.
    • (1998) Nat Biotech , vol.16 , pp. 547-552
    • Mahajan1
  • 29
    • 0028901215 scopus 로고
    • The lurcher gene induces apoptotic death in cerebellar Purkinje cells
    • Norman D, Feng L, Gubbay J, Chan E, Heintz N (1995) The lurcher gene induces apoptotic death in cerebellar Purkinje cells. Development 121:1183-1193.
    • (1995) Development , vol.121 , pp. 1183-1193
    • Norman, D.1    Feng, L.2    Gubbay, J.3    Chan, E.4    Heintz, N.5
  • 30
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
    • Oltvai ZN, Milliman CL, Korsmeyer SJ (1993) Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 74:609-619.
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltvai, Z.N.1    Milliman, C.L.2    Korsmeyer, S.J.3
  • 31
  • 32
    • 0002279362 scopus 로고
    • "Lurcher," a new gene in linkage group XI of the house mouse
    • Phillips RJS (1960) "Lurcher," a new gene in linkage group XI of the house mouse. J Genet 57:35-42.
    • (1960) J Genet , vol.57 , pp. 35-42
    • Phillips, R.J.S.1
  • 33
    • 0033579301 scopus 로고    scopus 로고
    • Mediation by a CREB family transcription factor of NGF-dependent survival of sympathetic neurons
    • Riccio A, Ahn S, Davenport CM, Blendy JA, Ginty DD (1999) Mediation by a CREB family transcription factor of NGF-dependent survival of sympathetic neurons. Science 286:2358-2361.
    • (1999) Science , vol.286 , pp. 2358-2361
    • Riccio, A.1    Ahn, S.2    Davenport, C.M.3    Blendy, J.A.4    Ginty, D.D.5
  • 34
    • 0034143430 scopus 로고    scopus 로고
    • Target-related and intrinsic neuronal death in Lurcher mutant mice are both mediated by caspase-3 activation
    • Selimi F, Doughty M, Delhaye-Bouchaud N, Mariani J (2000) Target-related and intrinsic neuronal death in Lurcher mutant mice are both mediated by caspase-3 activation. J Neurosci 20:992-1000.
    • (2000) J Neurosci , vol.20 , pp. 992-1000
    • Selimi, F.1    Doughty, M.2    Delhaye-Bouchaud, N.3    Mariani, J.4
  • 35
    • 0030898680 scopus 로고    scopus 로고
    • Bax deficiency prevents the increased cell death of immature neurons in bcl-x-deficient mice
    • Shindler KS, Latham CB, Roth KA (1997) Bax deficiency prevents the increased cell death of immature neurons in bcl-x-deficient mice. J Neurosci 17:3112-3119.
    • (1997) J Neurosci , vol.17 , pp. 3112-3119
    • Shindler, K.S.1    Latham, C.B.2    Roth, K.A.3
  • 37
    • 0015946987 scopus 로고
    • Transsynaptic degeneration "en cascade" in the cerebellar cortex of staggerer mutant mice
    • Sotelo C, Changeux J-P (1974) Transsynaptic degeneration "en cascade" in the cerebellar cortex of staggerer mutant mice. Brain Res 67:519-526.
    • (1974) Brain Res , vol.67 , pp. 519-526
    • Sotelo, C.1    Changeux, J.-P.2
  • 38
    • 0032194215 scopus 로고    scopus 로고
    • Rate of neuronal fallout in a transsynaptic cerebellar model
    • Triarhou LC (1998) Rate of neuronal fallout in a transsynaptic cerebellar model. Brain Res Bull 47:219-222.
    • (1998) Brain Res Bull , vol.47 , pp. 219-222
    • Triarhou, L.C.1
  • 39
    • 0031001244 scopus 로고    scopus 로고
    • Bax promotes neuronal cell death and is downregulated during the development of the nervous system
    • Vekrellis K, McCarthy MJ, Watson A, Whitfield J, Rubin LL, Ham J (1997) Bax promotes neuronal cell death and is downregulated during the development of the nervous system. Development 124:1239-1249.
    • (1997) Development , vol.124 , pp. 1239-1249
    • Vekrellis, K.1    McCarthy, M.J.2    Watson, A.3    Whitfield, J.4    Rubin, L.L.5    Ham, J.6
  • 40
    • 0025833711 scopus 로고
    • Cerebellar Purkinje cells provide target support over a limited spatial range: Evidence from lurcher chimeric mice
    • Vogel MW, McInnes M, Zanjani HS, Herrup K (1991) Cerebellar Purkinje cells provide target support over a limited spatial range: evidence from lurcher chimeric mice. Dev Brain Res 64:87-94.
    • (1991) Dev Brain Res , vol.64 , pp. 87-94
    • Vogel, M.W.1    McInnes, M.2    Zanjani, H.S.3    Herrup, K.4
  • 41
    • 0020004251 scopus 로고
    • Interaction of granule, Purkinje and inferiorolivary neurons in lurcher chimeric mice. I. Qualitative studies
    • Wetts R, Herrup K (1982a) Interaction of granule, Purkinje and inferiorolivary neurons in lurcher chimeric mice. I. Qualitative studies. J Embryol Exp Morphol 68:87-98.
    • (1982) J Embryol Exp Morphol , vol.68 , pp. 87-98
    • Wetts, R.1    Herrup, K.2
  • 42
    • 0019916759 scopus 로고
    • Interaction of granule, Purkinje and inferior olivary neurons in lurcher chimeric mice. II. Granule cell death
    • Wetts R, Herrup K (1982b) Interaction of granule, Purkinje and inferior olivary neurons in lurcher chimeric mice. II. Granule cell death. Brain Res 250:358-363.
    • (1982) Brain Res , vol.250 , pp. 358-363
    • Wetts, R.1    Herrup, K.2
  • 43
    • 0032520195 scopus 로고    scopus 로고
    • Widespread elimination of naturally occurring neuronal death in Bax-deficient mice
    • White FA, Keller-Peck CR, Knudson M, Korsmeyer SJ, Snider WD (1998) Widespread elimination of naturally occurring neuronal death in Bax-deficient mice. J Neurosci 18:1428-1439.
    • (1998) J Neurosci , vol.18 , pp. 1428-1439
    • White, F.A.1    Keller-Peck, C.R.2    Knudson, M.3    Korsmeyer, S.J.4    Snider, W.D.5
  • 44
    • 0028783320 scopus 로고
    • Apoptotic cell death in the cerebellum of mutant weaver and lurcher mice
    • Wullner U, Loschmann P-A, Weller M, Klockgether T (1995) Apoptotic cell death in the cerebellum of mutant weaver and lurcher mice. Neurosci Lett 200:109-112.
    • (1995) Neurosci Lett , vol.200 , pp. 109-112
    • Wullner, U.1    Loschmann, P.-A.2    Weller, M.3    Klockgether, T.4
  • 46
    • 0025470048 scopus 로고
    • Cell loss in the inferior olive of the staggerer mutant mouse is an indirect effect of the gene
    • Zanjani HS, Mariani J, Herrup K (1990) Cell loss in the inferior olive of the staggerer mutant mouse is an indirect effect of the gene. J Neurogenet 6:229-241.
    • (1990) J Neurogenet , vol.6 , pp. 229-241
    • Zanjani, H.S.1    Mariani, J.2    Herrup, K.3
  • 48
    • 0031974178 scopus 로고    scopus 로고
    • Postnatal expression of Hu-Bcl-2 gene in Lurcher mutant mice fails to rescue Purkinje cells, but protects inferior olivary neurons from target related cell death
    • Zanjani HS, Vogel MW, Martinou JC, Delhaye-Bouchaud N, Mariani J (1998b) Postnatal expression of Hu-Bcl-2 gene in Lurcher mutant mice fails to rescue Purkinje cells, but protects inferior olivary neurons from target related cell death. J Neurosci 18:319-327.
    • (1998) J Neurosci , vol.18 , pp. 319-327
    • Zanjani, H.S.1    Vogel, M.W.2    Martinou, J.C.3    Delhaye-Bouchaud, N.4    Mariani, J.5
  • 49
    • 0030800468 scopus 로고    scopus 로고
    • Neurodegeneration in Lurcher mice caused by mutation in δ2 glutamate receptor
    • Zuo J, De Jager PL, Takahashi KA, Jiang W, Linden DJ, Heintz N (1997) Neurodegeneration in Lurcher mice caused by mutation in δ2 glutamate receptor. Nature 388:769-773.
    • (1997) Nature , vol.388 , pp. 769-773
    • Zuo, J.1    De Jager, P.L.2    Takahashi, K.A.3    Jiang, W.4    Linden, D.J.5    Heintz, N.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.