메뉴 건너뛰기




Volumn 22, Issue 9, 2002, Pages 3531-3542

Inhibition of Protein Kinase C Prevents Purkinje Cell Death but Does Not Affect Axonal Regeneration

Author keywords

Apoptosis; Axotomy; Cerebellum; Development; PKC inhibitor; Trophic factor

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; GREEN FLUORESCENT PROTEIN; NEUROTROPHIN 3; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; SOMATOMEDIN; 12 (2 CYANOETHYL) 6,7,12,13 TETRAHYDRO 13 METHYL 5 OXOINDOLO[2,3 A]PYRROLO[3,4 C]CARBAZOLE; BRAIN DERIVED NEUROTROPHIC FACTOR; CARBAZOLE DERIVATIVE; ENZYME INHIBITOR; INDOLE DERIVATIVE; SOMATOMEDIN C;

EID: 0036580678     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.22-09-03531.2002     Document Type: Article
Times cited : (67)

References (50)
  • 1
    • 0031019589 scopus 로고    scopus 로고
    • Ataxia and altered dendritic calcium signaling in mice carrying a targeted null mutation of the calbindin D28k gene
    • Airaksinen MS, Eilers J, Garaschuk O, Thoenen H, Konnerth A, Meyer M (1997) Ataxia and altered dendritic calcium signaling in mice carrying a targeted null mutation of the calbindin D28k gene. Proc Natl Acad Sci USA 94:1488-1493.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 1488-1493
    • Airaksinen, M.S.1    Eilers, J.2    Garaschuk, O.3    Thoenen, H.4    Konnerth, A.5    Meyer, M.6
  • 2
    • 0025718482 scopus 로고
    • Early dendritic development of Purkinje cells in the rat cerebellum. A light and electron microscopic study using axonal tracing in "in vitro" slices
    • Armengol JA, Sotelo C (1991) Early dendritic development of Purkinje cells in the rat cerebellum. A light and electron microscopic study using axonal tracing in "in vitro" slices. Brain Res Dev Brain Res 64:95-114.
    • (1991) Brain Res Dev Brain Res , vol.64 , pp. 95-114
    • Armengol, J.A.1    Sotelo, C.2
  • 3
    • 0028077107 scopus 로고
    • A strategy for the analysis of gene expression during neural development
    • Arnold D, Feng L, Kim J, Heintz N (1994) A strategy for the analysis of gene expression during neural development. Proc Natl Acad Sci USA 91:9970-9974.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 9970-9974
    • Arnold, D.1    Feng, L.2    Kim, J.3    Heintz, N.4
  • 4
    • 0028346797 scopus 로고
    • Cell-cell interactions influence survival and differentiation of purified Purkinje cells in vitro
    • Baptista CA, Hatten ME, Blazeski R, Mason CA (1994) Cell-cell interactions influence survival and differentiation of purified Purkinje cells in vitro. Neuron 2:243-260.
    • (1994) Neuron , vol.2 , pp. 243-260
    • Baptista, C.A.1    Hatten, M.E.2    Blazeski, R.3    Mason, C.A.4
  • 5
    • 0025938153 scopus 로고
    • Localization of insulin-like growth factor-1 mRNA in murine central nervous system during postnatal development
    • Bartlett WP, Li XS, Williams M, Benkovic S (1991) Localization of insulin-like growth factor-1 mRNA in murine central nervous system during postnatal development. Dev Biol 147:239-250.
    • (1991) Dev Biol , vol.147 , pp. 239-250
    • Bartlett, W.P.1    Li, X.S.2    Williams, M.3    Benkovic, S.4
  • 6
    • 0032588967 scopus 로고    scopus 로고
    • Gö6976 is a potent inhibitor of neurotrophin-receptor intrinsic tyrosine kinase
    • Behrens MM, Strasser U, Choi DW (1998) Gö6976 is a potent inhibitor of neurotrophin-receptor intrinsic tyrosine kinase. J Neurochem 72:919-924.
    • (1998) J Neurochem , vol.72 , pp. 919-924
    • Behrens, M.M.1    Strasser, U.2    Choi, D.W.3
  • 7
    • 0031027044 scopus 로고    scopus 로고
    • GAP-43: An intrinsic determinant of neuronal development and plasticity
    • Benowitz LI, Routtenberg A (1997) GAP-43: an intrinsic determinant of neuronal development and plasticity. Trends Neurosci 20:84-91.
    • (1997) Trends Neurosci , vol.20 , pp. 84-91
    • Benowitz, L.I.1    Routtenberg, A.2
  • 8
    • 0028338831 scopus 로고
    • NGF and the local control of nerve terminal growth
    • Campenot RB (1994) NGF and the local control of nerve terminal growth. J Neurobiol 25:599-611.
    • (1994) J Neurobiol , vol.25 , pp. 599-611
    • Campenot, R.B.1
  • 9
    • 0025358573 scopus 로고
    • Calbindin D-28k and parvalbumin in the rat nervous system
    • Celio MR (1990) Calbindin D-28k and parvalbumin in the rat nervous system. Neuroscience 35:375-475.
    • (1990) Neuroscience , vol.35 , pp. 375-475
    • Celio, M.R.1
  • 10
    • 0027744203 scopus 로고
    • The "creeper stage" in cerebellar climbing fiber synaptogenesis precedes the "pericellular nest"-ultrastructural evidence with parvalbumin immunocytochemistry
    • Chedotal A, Sotelo C (1993) The "creeper stage" in cerebellar climbing fiber synaptogenesis precedes the "pericellular nest"-ultrastructural evidence with parvalbumin immunocytochemistry. Dev Brain Res 76:207-220.
    • (1993) Dev Brain Res , vol.76 , pp. 207-220
    • Chedotal, A.1    Sotelo, C.2
  • 11
    • 0027297043 scopus 로고
    • New fluorescent probes for protein kinase C. Synthesis, characterization, and application
    • Chen CS, Poenie M (1993) New fluorescent probes for protein kinase C. Synthesis, characterization, and application. J Biol Chem 268:15812-15822.
    • (1993) J Biol Chem , vol.268 , pp. 15812-15822
    • Chen, C.S.1    Poenie, M.2
  • 12
    • 0024380143 scopus 로고
    • Expression of high- and low-affinity nerve growth factor receptors by Purkinje cells in the developing rat cerebellum
    • Cohen-Cory S, Dreyfus CF, Black IB (1989) Expression of high- and low-affinity nerve growth factor receptors by Purkinje cells in the developing rat cerebellum. Exp Neurol 105:104-109.
    • (1989) Exp Neurol , vol.105 , pp. 104-109
    • Cohen-Cory, S.1    Dreyfus, C.F.2    Black, I.B.3
  • 13
    • 0018843498 scopus 로고
    • Dendritic and axonic fields of Purkinje cells in developing and x-irradiated rat cerebellum. A comparative study using intracellular staining with horseradish peroxidase
    • Crepel F, Delhaye-Bouchaud N, Dupont JL, Sotelo C (1980) Dendritic and axonic fields of Purkinje cells in developing and x-irradiated rat cerebellum. A comparative study using intracellular staining with horseradish peroxidase. Neuroscience 5:333-347.
    • (1980) Neuroscience , vol.5 , pp. 333-347
    • Crepel, F.1    Delhaye-Bouchaud, N.2    Dupont, J.L.3    Sotelo, C.4
  • 14
    • 0028232469 scopus 로고
    • Protein kinase C activation inhibits glutamate-induced cytotoxicity in a neuronal cell line
    • Davis JB, Maher P (1994) Protein kinase C activation inhibits glutamate-induced cytotoxicity in a neuronal cell line. Brain Res 652:169-173.
    • (1994) Brain Res , vol.652 , pp. 169-173
    • Davis, J.B.1    Maher, P.2
  • 16
    • 0032031999 scopus 로고    scopus 로고
    • Expression of a protein kinase C inhibitor in Purkinje cells blocks cerebellar LTD and adaptation of the vestibuloocular reflex
    • De Zeeuw CI, Hansel C, Bian F, Koekkoek SK, van Alphen AM, Linden DJ, Oberdick J (1998) Expression of a protein kinase C inhibitor in Purkinje cells blocks cerebellar LTD and adaptation of the vestibuloocular reflex. Neuron 20:495-508.
    • (1998) Neuron , vol.20 , pp. 495-508
    • De Zeeuw, C.I.1    Hansel, C.2    Bian, F.3    Koekkoek, S.K.4    Van Alphen, A.M.5    Linden, D.J.6    Oberdick, J.7
  • 17
    • 0030969909 scopus 로고    scopus 로고
    • Purkinje cell survival and axonal regeneration are age dependent: An in vitro study
    • Dusart I, Airaksinen MS, Sotelo C (1997) Purkinje cell survival and axonal regeneration are age dependent: an in vitro study. J Neurosci 17:3710-3726.
    • (1997) J Neurosci , vol.17 , pp. 3710-3726
    • Dusart, I.1    Airaksinen, M.S.2    Sotelo, C.3
  • 19
    • 0027478471 scopus 로고
    • Inhibitors of protein kinase C prevent the toxicity of glutamate in primary neuronal cultures
    • Felipo V, Minana MD, Grisolia S (1993) Inhibitors of protein kinase C prevent the toxicity of glutamate in primary neuronal cultures. Brain Res 604:192-196.
    • (1993) Brain Res , vol.604 , pp. 192-196
    • Felipo, V.1    Minana, M.D.2    Grisolia, S.3
  • 21
    • 0033811985 scopus 로고    scopus 로고
    • Implication of Bcl-2 and caspase-3 in the age-related Purkinje cell death in murine organotypic culture: An in vitro model to study apoptosis
    • Ghoumari AM, Wehrlé R, Bernard O, Sotelo C, Dusart I (2000) Implication of Bcl-2 and caspase-3 in the age-related Purkinje cell death in murine organotypic culture: an in vitro model to study apoptosis. Eur J Neurosci 12:2935-2949.
    • (2000) Eur J Neurosci , vol.12 , pp. 2935-2949
    • Ghoumari, A.M.1    Wehrlé, R.2    Bernard, O.3    Sotelo, C.4    Dusart, I.5
  • 22
    • 0035966676 scopus 로고    scopus 로고
    • Evolution of the Purkinje cell response to injury and regenerative potential during postnatal development of the rat cerebellum
    • Gianola S, Rossi F (2001) Evolution of the Purkinje cell response to injury and regenerative potential during postnatal development of the rat cerebellum. J Comp Neurol 430:101-117.
    • (2001) J Comp Neurol , vol.430 , pp. 101-117
    • Gianola, S.1    Rossi, F.2
  • 23
    • 0034078885 scopus 로고    scopus 로고
    • The relationship between neuronal survival and regeneration
    • Goldberg JL, Barres BA (2000) The relationship between neuronal survival and regeneration. Annu Rev Neurosci 23:579-612.
    • (2000) Annu Rev Neurosci , vol.23 , pp. 579-612
    • Goldberg, J.L.1    Barres, B.A.2
  • 24
    • 0029964643 scopus 로고    scopus 로고
    • Role of neurotrophic factors in neuronal development
    • Henderson CE (1996) Role of neurotrophic factors in neuronal development. Curr Opin Neurobiol 6:64-70.
    • (1996) Curr Opin Neurobiol , vol.6 , pp. 64-70
    • Henderson, C.E.1
  • 25
    • 0031149046 scopus 로고    scopus 로고
    • The c-Jun transcription factor: Bipotential mediator of neuronal death, survival and regeneration
    • Herdegen T, Skene P, Bahr M (1997) The c-Jun transcription factor: bipotential mediator of neuronal death, survival and regeneration. Trends Neurosci 20:227-231.
    • (1997) Trends Neurosci , vol.20 , pp. 227-231
    • Herdegen, T.1    Skene, P.2    Bahr, M.3
  • 26
    • 0034044227 scopus 로고    scopus 로고
    • Neurotrophin signal transduction in the nervous system
    • Kaplan DR, Miller FD (2000) Neurotrophin signal transduction in the nervous system. Curr Opin Neurobiol 10:381-391.
    • (2000) Curr Opin Neurobiol , vol.10 , pp. 381-391
    • Kaplan, D.R.1    Miller, F.D.2
  • 27
    • 0029933495 scopus 로고    scopus 로고
    • Characterization of the responses of Purkinje cells to neurotrophin treatment
    • Larkfors L, Lindsay RM, Alderson RF (1996) Characterization of the responses of Purkinje cells to neurotrophin treatment. J Neurochem 66:1362-1373.
    • (1996) J Neurochem , vol.66 , pp. 1362-1373
    • Larkfors, L.1    Lindsay, R.M.2    Alderson, R.F.3
  • 28
    • 0023236055 scopus 로고
    • The nerve growth factor 35 years later
    • Levi-Montalcini R (1987) The nerve growth factor 35 years later. Science 237:1154-1162.
    • (1987) Science , vol.237 , pp. 1154-1162
    • Levi-Montalcini, R.1
  • 29
    • 0026783290 scopus 로고
    • An electrophysiological correlate of protein kinase C isozyme distribution in cultured cerebellar neurons
    • Linden DL, Smeyne M, Sun SC, Connor JA (1992) An electrophysiological correlate of protein kinase C isozyme distribution in cultured cerebellar neurons. J Neurosci 12:3601-3608.
    • (1992) J Neurosci , vol.12 , pp. 3601-3608
    • Linden, D.L.1    Smeyne, M.2    Sun, S.C.3    Connor, J.A.4
  • 30
    • 0027423233 scopus 로고
    • Brain-derived neurotrophic factor is a survival factor for cultured rat cerebellar granule neurons and protects them against glutamate-induced neurotoxicity
    • Lindholm D, Dechant G, Heisenberg CP, Thoenen H (1993) Brain-derived neurotrophic factor is a survival factor for cultured rat cerebellar granule neurons and protects them against glutamate-induced neurotoxicity. Eur J Neurosci 5:1455-1464.
    • (1993) Eur J Neurosci , vol.5 , pp. 1455-1464
    • Lindholm, D.1    Dechant, G.2    Heisenberg, C.P.3    Thoenen, H.4
  • 32
    • 0028608147 scopus 로고
    • Neuronal transfection in brain slices using particle-mediated gene transfer
    • Lo DC, McAllister AK, Katz LC (1994) Neuronal transfection in brain slices using particle-mediated gene transfer. Neuron 13:1263-1268.
    • (1994) Neuron , vol.13 , pp. 1263-1268
    • Lo, D.C.1    McAllister, A.K.2    Katz, L.C.3
  • 33
    • 0030033442 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor promotes the differentiation of various hippocampal nonpyramidal neurons, including Cajal-Retzius cells, in organotypic slice cultures
    • Marty S, Carroll P, Cellerino A, Castren E, Staiger V, Thoenen H, Lindholm D (1996) Brain-derived neurotrophic factor promotes the differentiation of various hippocampal nonpyramidal neurons, including Cajal-Retzius cells, in organotypic slice cultures. J Neurosci 16:675-687.
    • (1996) J Neurosci , vol.16 , pp. 675-687
    • Marty, S.1    Carroll, P.2    Cellerino, A.3    Castren, E.4    Staiger, V.5    Thoenen, H.6    Lindholm, D.7
  • 34
    • 0034090001 scopus 로고    scopus 로고
    • Protein kinase C activity modulates dendritic differentiation of rat Purkinje cells in cerebellar slice cultures
    • Metzger F, Kapfhammer JP (2000) Protein kinase C activity modulates dendritic differentiation of rat Purkinje cells in cerebellar slice cultures. Eur J Neurosci 12:1993-2005.
    • (2000) Eur J Neurosci , vol.12 , pp. 1993-2005
    • Metzger, F.1    Kapfhammer, J.P.2
  • 35
    • 0028867186 scopus 로고
    • Characterization of the signaling interactions that promote the survival and growth of developing retinal ganglion cells in culture
    • Meyer-Franke A, Kaplan MR, Pfrieger FW, Barres BA (1995) Characterization of the signaling interactions that promote the survival and growth of developing retinal ganglion cells in culture. Neuron 15:805-819.
    • (1995) Neuron , vol.15 , pp. 805-819
    • Meyer-Franke, A.1    Kaplan, M.R.2    Pfrieger, F.W.3    Barres, B.A.4
  • 36
    • 0029807584 scopus 로고    scopus 로고
    • TrkB and TrkC neurotrophin receptors cooperate in promoting survival of hippocampal and cerebellar granule neurons
    • Minichiello L, Klein R (1996) TrkB and TrkC neurotrophin receptors cooperate in promoting survival of hippocampal and cerebellar granule neurons. Genes Dev 10:2849-2858.
    • (1996) Genes Dev , vol.10 , pp. 2849-2858
    • Minichiello, L.1    Klein, R.2
  • 37
    • 0032525317 scopus 로고    scopus 로고
    • Granule neuron regulation of Purkinje cell development: Striking a balance between neurotrophin and glutamate signaling
    • Morrison ME, Mason CA (1998) Granule neuron regulation of Purkinje cell development: striking a balance between neurotrophin and glutamate signaling. J Neurosci 18:3563-3573.
    • (1998) J Neurosci , vol.18 , pp. 3563-3573
    • Morrison, M.E.1    Mason, C.A.2
  • 38
    • 0028143741 scopus 로고
    • Muscarinic stimulation promotes cultured Purkinje cell survival: A role for acetylcholine in cerebellar development?
    • Mount HT, Dreyfus CF, Black IB (1994) Muscarinic stimulation promotes cultured Purkinje cell survival: a role for acetylcholine in cerebellar development? J Neurochem 63:2065-2073.
    • (1994) J Neurochem , vol.63 , pp. 2065-2073
    • Mount, H.T.1    Dreyfus, C.F.2    Black, I.B.3
  • 39
    • 0034221202 scopus 로고    scopus 로고
    • The role of protein kinase C isoforms in cell proliferation and apoptosis
    • Musashi M, Ota S, Shiroshita N (2000) The role of protein kinase C isoforms in cell proliferation and apoptosis. Int J Hematol 72:12-19.
    • (2000) Int J Hematol , vol.72 , pp. 12-19
    • Musashi, M.1    Ota, S.2    Shiroshita, N.3
  • 40
    • 0026451081 scopus 로고
    • Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C
    • Nishizuka Y (1992) Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C. Science 258:607-614.
    • (1992) Science , vol.258 , pp. 607-614
    • Nishizuka, Y.1
  • 41
    • 0026328171 scopus 로고
    • Electrical activity in cerebellar cultures determines Purkinje cell dendritic growth pattern
    • Schilling K, Dickinson M, Connor JA, Morgan JI (1991) Electrical activity in cerebellar cultures determines Purkinje cell dendritic growth pattern. Neuron 7:891-902.
    • (1991) Neuron , vol.7 , pp. 891-902
    • Schilling, K.1    Dickinson, M.2    Connor, J.A.3    Morgan, J.I.4
  • 42
    • 0034661795 scopus 로고    scopus 로고
    • TrkB receptor ligands promote activity-dependent inhibitory synaptogenesis
    • Seil FJ, Drake-Baumann R (2000) TrkB receptor ligands promote activity-dependent inhibitory synaptogenesis. J Neurosci 20:5367-5373.
    • (2000) J Neurosci , vol.20 , pp. 5367-5373
    • Seil, F.J.1    Drake-Baumann, R.2
  • 43
    • 0018227975 scopus 로고
    • Purkinje cell ontogeny: Formation and maintenance of spines
    • Sotelo C (1978) Purkinje cell ontogeny: formation and maintenance of spines. Prog Brain Res 48:149-170.
    • (1978) Prog Brain Res , vol.48 , pp. 149-170
    • Sotelo, C.1
  • 44
    • 0025805120 scopus 로고
    • A simple method for organotypic cultures of nervous tissue
    • Stoppini L, Buchs PA, Muller D (1991) A simple method for organotypic cultures of nervous tissue. J Neurosci Methods 37:173-182.
    • (1991) J Neurosci Methods , vol.37 , pp. 173-182
    • Stoppini, L.1    Buchs, P.A.2    Muller, D.3
  • 45
    • 0028133016 scopus 로고
    • The insulin-like growth factor I system in the rat cerebellum: Developmental regulation and role in neuronal survival and differentiation
    • Torres-Aleman I, Pons S, Arevalo MA (1994) The insulin-like growth factor I system in the rat cerebellum: developmental regulation and role in neuronal survival and differentiation. J Neurosci Res 39:117-126.
    • (1994) J Neurosci Res , vol.39 , pp. 117-126
    • Torres-Aleman, I.1    Pons, S.2    Arevalo, M.A.3
  • 46
    • 0032959871 scopus 로고    scopus 로고
    • Control of neuronal precursor proliferation in the cerebellum by Sonic Hedgehog
    • Wechsler-Reya RJ, Scott MP (1999) Control of neuronal precursor proliferation in the cerebellum by Sonic Hedgehog. Neuron 22:103-114.
    • (1999) Neuron , vol.22 , pp. 103-114
    • Wechsler-Reya, R.J.1    Scott, M.P.2
  • 47
    • 0035108243 scopus 로고    scopus 로고
    • Role of GAP-43 in mediating the responsiveness of cerebellar and precerebellar neurons to axotomy
    • Wehrlé R, Caroni P, Sotelo C, Dusart I (2001) Role of GAP-43 in mediating the responsiveness of cerebellar and precerebellar neurons to axotomy. Eur J Neurosci 13:857-870.
    • (2001) Eur J Neurosci , vol.13 , pp. 857-870
    • Wehrlé, R.1    Caroni, P.2    Sotelo, C.3    Dusart, I.4
  • 48
    • 0032705581 scopus 로고    scopus 로고
    • Optimized protocol for biolistic transfection of brain slices and dissociated cultured neurons with a hand-held gene gun
    • Wellmann H, Kaltschmidt B, Kaltschmidt C (1999) Optimized protocol for biolistic transfection of brain slices and dissociated cultured neurons with a hand-held gene gun. J Neurosci Methods 92:55-64.
    • (1999) J Neurosci Methods , vol.92 , pp. 55-64
    • Wellmann, H.1    Kaltschmidt, B.2    Kaltschmidt, C.3
  • 49
    • 0023687398 scopus 로고
    • An immunohistochemical study of the nerve growth factor receptor in developing rats
    • Yan Q, Johnson Jr EM (1988) An immunohistochemical study of the nerve growth factor receptor in developing rats. J Neurosci 8:3481-3498.
    • (1988) J Neurosci , vol.8 , pp. 3481-3498
    • Yan, Q.1    Johnson Jr., E.M.2
  • 50
    • 0031841549 scopus 로고    scopus 로고
    • i in avian cochlear nucleus neurons: Roles of protein kinases A and C and relation to cell death
    • i in avian cochlear nucleus neurons: roles of protein kinases A and C and relation to cell death. J Neurophysiol 79:2288-2302.
    • (1998) J Neurophysiol , vol.79 , pp. 2288-2302
    • Zirpel, L.1    Lippe, W.R.2    Rubel, E.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.