Structural dynamics of the MecA-ClpC complex: A type II AAA+ protein unfolding machine

Journal of Biological Chemistry

Volumn 288, Issue 24, 2013, Pages 17597-17608

  Liu, Jing ^a   Mei, Ziqing ^a   Li, Ningning ^a   Qi, Yutao ^a   Xu, Yanji ^a   Shi, Yigong ^a,b   Wang, Feng ^a   Lei, Jianlin ^a   Gao, Ning ^a  

^a TSINGHUA UNIVERSITY   (China)

^b Tsinghua University   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOSTERIC COMMUNICATION; CRYO-ELECTRON MICROSCOPY; DIFFERENT STRUCTURE; MECHANISTIC MODELS; MOLECULAR MACHINES; NUCLEOTIDE BINDING; NUCLEOTIDE-BINDING DOMAIN; RELATIVE ROTATION;

NUCLEOTIDES; STRUCTURAL DYNAMICS; STRUCTURE (COMPOSITION); TRANSCRIPTION FACTORS;

SUBSTRATES;

ENDOPEPTIDASE CLP; ENDOPEPTIDASE CLPC; PENICILLIN BINDING PROTEIN 2A; UNCLASSIFIED DRUG;

ALLOSTERISM; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYOELECTRON MICROSCOPY; HYDROLYSIS; NONHUMAN; NUCLEOTIDE BINDING SITE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; PROTEIN UNFOLDING; STRUCTURE ANALYSIS;

AAA+ HEXAMERS; ATP-DEPENDENT PROTEASE; ATPASES; CLPC; ELECTRON MICROSCOPY (EM); HSP100; MECA; PROTEIN DEGRADATION; PROTEIN STRUCTURE; PROTEIN UNFOLDING MACHINE;

ADENOSINE TRIPHOSPHATE; ALLOSTERIC REGULATION; AMINO ACID SUBSTITUTION; BACILLUS SUBTILIS; BACTERIAL PROTEINS; BINDING SITES; CRYOELECTRON MICROSCOPY; HEAT-SHOCK PROTEINS; HYDROLYSIS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN STRUCTURE, QUATERNARY; PROTEIN UNFOLDING;

BACTERIA (MICROORGANISMS);

EID: 84879061703     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.458752     Document Type: Article

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