-
1
-
-
27844460608
-
Biochemical coupling of the two nucleotide binding domains of ClpB: Covalent linkage is not a prerequisite for chaperone activity
-
Beinker P., Schlee S., Auvula R., and Reinstein J. Biochemical coupling of the two nucleotide binding domains of ClpB: Covalent linkage is not a prerequisite for chaperone activity. J. Biol. Chem. 280 (2005) 37965-37973
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 37965-37973
-
-
Beinker, P.1
Schlee, S.2
Auvula, R.3
Reinstein, J.4
-
2
-
-
33646582995
-
Conformational changes in the AAA ATPase p97-p47 adaptor complex
-
Beuron F., Dreveny I., Yuan X., Pye V.E., McKeown C., Briggs L.C., Cliff M.J., Kaneko Y., Wallis R., Isaacson R.L., et al. Conformational changes in the AAA ATPase p97-p47 adaptor complex. EMBO J. 25 (2006) 1967-1976
-
(2006)
EMBO J.
, vol.25
, pp. 1967-1976
-
-
Beuron, F.1
Dreveny, I.2
Yuan, X.3
Pye, V.E.4
McKeown, C.5
Briggs, L.C.6
Cliff, M.J.7
Kaneko, Y.8
Wallis, R.9
Isaacson, R.L.10
-
3
-
-
0034677361
-
The structures of HslU and the ATP-dependent protease HslU-HslV
-
Bochtler M., Hartmann C., Song H.K., Bourenkov G.P., Bartunik H.D., and Huber R. The structures of HslU and the ATP-dependent protease HslU-HslV. Nature 403 (2000) 800-805
-
(2000)
Nature
, vol.403
, pp. 800-805
-
-
Bochtler, M.1
Hartmann, C.2
Song, H.K.3
Bourenkov, G.P.4
Bartunik, H.D.5
Huber, R.6
-
4
-
-
5344266886
-
Nucleotide-dependent substrate handoff from the SspB adaptor to the AAA+ ClpXP protease
-
Bolon D.N., Grant R.A., Baker T.A., and Sauer R.T. Nucleotide-dependent substrate handoff from the SspB adaptor to the AAA+ ClpXP protease. Mol. Cell 16 (2004) 343-350
-
(2004)
Mol. Cell
, vol.16
, pp. 343-350
-
-
Bolon, D.N.1
Grant, R.A.2
Baker, T.A.3
Sauer, R.T.4
-
5
-
-
31444442284
-
Substrate binding to the molecular chaperone Hsp104 and its regulation by nucleotides
-
Bosl B., Grimminger V., and Walter S. Substrate binding to the molecular chaperone Hsp104 and its regulation by nucleotides. J. Biol. Chem. 280 (2005) 38170-38176
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 38170-38176
-
-
Bosl, B.1
Grimminger, V.2
Walter, S.3
-
6
-
-
46649111025
-
Analysis of nucleotide binding to P97 reveals the properties of a tandem AAA hexameric ATPase
-
Briggs L.C., Baldwin G.S., Miyata N., Kondo H., Zhang X., and Freemont P.S. Analysis of nucleotide binding to P97 reveals the properties of a tandem AAA hexameric ATPase. J. Biol. Chem. 283 (2008) 13745-13752
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 13745-13752
-
-
Briggs, L.C.1
Baldwin, G.S.2
Miyata, N.3
Kondo, H.4
Zhang, X.5
Freemont, P.S.6
-
7
-
-
0036238432
-
Defining a pathway of communication from the C-terminal peptide binding domain to the N-terminal ATPase domain in a AAA protein
-
Cashikar A.G., Schirmer E.C., Hattendorf D.A., Glover J.R., Ramakrishnan M.S., Ware D.M., and Lindquist S.L. Defining a pathway of communication from the C-terminal peptide binding domain to the N-terminal ATPase domain in a AAA protein. Mol. Cell 9 (2002) 751-760
-
(2002)
Mol. Cell
, vol.9
, pp. 751-760
-
-
Cashikar, A.G.1
Schirmer, E.C.2
Hattendorf, D.A.3
Glover, J.R.4
Ramakrishnan, M.S.5
Ware, D.M.6
Lindquist, S.L.7
-
9
-
-
0141507032
-
Complete structure of p97/valosin-containing protein reveals communication between nucleotide domains
-
DeLaBarre B., and Brunger A.T. Complete structure of p97/valosin-containing protein reveals communication between nucleotide domains. Nat. Struct. Biol. 10 (2003) 856-863
-
(2003)
Nat. Struct. Biol.
, vol.10
, pp. 856-863
-
-
DeLaBarre, B.1
Brunger, A.T.2
-
10
-
-
14644415865
-
Nucleotide dependent motion and mechanism of action of p97/VCP
-
DeLaBarre B., and Brunger A.T. Nucleotide dependent motion and mechanism of action of p97/VCP. J. Mol. Biol. 347 (2005) 437-452
-
(2005)
J. Mol. Biol.
, vol.347
, pp. 437-452
-
-
DeLaBarre, B.1
Brunger, A.T.2
-
11
-
-
33846941900
-
Asymmetric deceleration of ClpB or Hsp104 ATPase activity unleashes protein-remodeling activity
-
Doyle S.M., Shorter J., Zolkiewski M., Hoskins J.R., Lindquist S., and Wickner S. Asymmetric deceleration of ClpB or Hsp104 ATPase activity unleashes protein-remodeling activity. Nat. Struct. Mol. Biol. 14 (2007) 114-122
-
(2007)
Nat. Struct. Mol. Biol.
, vol.14
, pp. 114-122
-
-
Doyle, S.M.1
Shorter, J.2
Zolkiewski, M.3
Hoskins, J.R.4
Lindquist, S.5
Wickner, S.6
-
12
-
-
33745041480
-
Evolutionary relationships and structural mechanisms of AAA+ proteins
-
Erzberger J.P., and Berger J.M. Evolutionary relationships and structural mechanisms of AAA+ proteins. Annu. Rev. Biophys. Biomol. Struct. 35 (2006) 93-114
-
(2006)
Annu. Rev. Biophys. Biomol. Struct.
, vol.35
, pp. 93-114
-
-
Erzberger, J.P.1
Berger, J.M.2
-
13
-
-
4444226952
-
Mechanisms of conformational change for a replicative hexameric helicase of SV40 large tumor antigen
-
Gai D., Zhao R., Li D., Finkielstein C.V., and Chen X.S. Mechanisms of conformational change for a replicative hexameric helicase of SV40 large tumor antigen. Cell 119 (2004) 47-60
-
(2004)
Cell
, vol.119
, pp. 47-60
-
-
Gai, D.1
Zhao, R.2
Li, D.3
Finkielstein, C.V.4
Chen, X.S.5
-
15
-
-
44849138934
-
Protein disaggregation by the AAA+ chaperone ClpB involves partial threading of looped polypeptide segments
-
Haslberger T., Zdanowicz A., Brand I., Kirstein J., Turgay K., Mogk A., and Bukau B. Protein disaggregation by the AAA+ chaperone ClpB involves partial threading of looped polypeptide segments. Nat. Struct. Mol. Biol. 15 (2008) 641-650
-
(2008)
Nat. Struct. Mol. Biol.
, vol.15
, pp. 641-650
-
-
Haslberger, T.1
Zdanowicz, A.2
Brand, I.3
Kirstein, J.4
Turgay, K.5
Mogk, A.6
Bukau, B.7
-
16
-
-
0037080611
-
Cooperative kinetics of both Hsp104 ATPase domains and interdomain communication revealed by AAA sensor-1 mutants
-
Hattendorf D.A., and Lindquist S.L. Cooperative kinetics of both Hsp104 ATPase domains and interdomain communication revealed by AAA sensor-1 mutants. EMBO J. 21 (2002) 12-21
-
(2002)
EMBO J.
, vol.21
, pp. 12-21
-
-
Hattendorf, D.A.1
Lindquist, S.L.2
-
17
-
-
21244482459
-
Asymmetric interactions of ATP with the AAA+ ClpX6 unfoldase: Allosteric control of a protein machine
-
Hersch G.L., Burton R.E., Bolon D.N., Baker T.A., and Sauer R.T. Asymmetric interactions of ATP with the AAA+ ClpX6 unfoldase: Allosteric control of a protein machine. Cell 121 (2005) 1017-1027
-
(2005)
Cell
, vol.121
, pp. 1017-1027
-
-
Hersch, G.L.1
Burton, R.E.2
Bolon, D.N.3
Baker, T.A.4
Sauer, R.T.5
-
18
-
-
21244480104
-
Loops in the central channel of ClpA chaperone mediate protein binding, unfolding, and translocation
-
Hinnerwisch J., Fenton W.A., Furtak K.J., Farr G.W., and Horwich A.L. Loops in the central channel of ClpA chaperone mediate protein binding, unfolding, and translocation. Cell 121 (2005) 1029-1041
-
(2005)
Cell
, vol.121
, pp. 1029-1041
-
-
Hinnerwisch, J.1
Fenton, W.A.2
Furtak, K.J.3
Farr, G.W.4
Horwich, A.L.5
-
19
-
-
34547963061
-
ATP-induced structural transitions in PAN, the proteasome-regulatory ATPase complex in Archaea
-
Horwitz A.A., Navon A., Groll M., Smith D.M., Reis C., and Goldberg A.L. ATP-induced structural transitions in PAN, the proteasome-regulatory ATPase complex in Archaea. J. Biol. Chem. 282 (2007) 22921-22929
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 22921-22929
-
-
Horwitz, A.A.1
Navon, A.2
Groll, M.3
Smith, D.M.4
Reis, C.5
Goldberg, A.L.6
-
20
-
-
33745419772
-
N-terminal domain of yeast Hsp104 chaperone is dispensable for thermotolerance and prion propagation but necessary for curing prions by Hsp104 overexpression
-
Hung G.C., and Masison D.C. N-terminal domain of yeast Hsp104 chaperone is dispensable for thermotolerance and prion propagation but necessary for curing prions by Hsp104 overexpression. Genetics 173 (2006) 611-620
-
(2006)
Genetics
, vol.173
, pp. 611-620
-
-
Hung, G.C.1
Masison, D.C.2
-
21
-
-
1242345623
-
The N-terminal substrate-binding domain of ClpA unfoldase is highly mobile and extends axially from the distal surface of ClpAP protease
-
Ishikawa T., Maurizi M.R., and Steven A.C. The N-terminal substrate-binding domain of ClpA unfoldase is highly mobile and extends axially from the distal surface of ClpAP protease. J. Struct. Biol. 146 (2004) 180-188
-
(2004)
J. Struct. Biol.
, vol.146
, pp. 180-188
-
-
Ishikawa, T.1
Maurizi, M.R.2
Steven, A.C.3
-
22
-
-
33947290033
-
Channel mutations in Hsp104 hexamer distinctively affect thermotolerance and prion-specific propagation
-
Kurahashi H., and Nakamura Y. Channel mutations in Hsp104 hexamer distinctively affect thermotolerance and prion-specific propagation. Mol. Microbiol. 63 (2007) 1669-1683
-
(2007)
Mol. Microbiol.
, vol.63
, pp. 1669-1683
-
-
Kurahashi, H.1
Nakamura, Y.2
-
23
-
-
33846188909
-
Visualizing the ATPase cycle in a protein disaggregating machine: Structural basis for substrate binding by ClpB
-
Lee S., Choi J.-M., and Tsai F.T.F. Visualizing the ATPase cycle in a protein disaggregating machine: Structural basis for substrate binding by ClpB. Mol. Cell 25 (2007) 261-271
-
(2007)
Mol. Cell
, vol.25
, pp. 261-271
-
-
Lee, S.1
Choi, J.-M.2
Tsai, F.T.F.3
-
24
-
-
0142227208
-
The structure of ClpB: A molecular chaperone that rescues proteins from an aggregated state
-
Lee S., Sowa M.E., Watanabe Y.H., Sigler P.B., Chiu W., Yoshida M., and Tsai F.T. The structure of ClpB: A molecular chaperone that rescues proteins from an aggregated state. Cell 115 (2003) 229-240
-
(2003)
Cell
, vol.115
, pp. 229-240
-
-
Lee, S.1
Sowa, M.E.2
Watanabe, Y.H.3
Sigler, P.B.4
Chiu, W.5
Yoshida, M.6
Tsai, F.T.7
-
25
-
-
3142657524
-
Evidence for an unfolding/threading mechanism for protein disaggregation by Saccharomyces cerevisiae Hsp104
-
Lum R., Tkach J.M., Vierling E., and Glover J.R. Evidence for an unfolding/threading mechanism for protein disaggregation by Saccharomyces cerevisiae Hsp104. J. Biol. Chem. 279 (2004) 29139-29146
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 29139-29146
-
-
Lum, R.1
Tkach, J.M.2
Vierling, E.3
Glover, J.R.4
-
26
-
-
57649187079
-
Peptide and protein binding in the axial channel of Hsp104. Insights into the mechanism of protein unfolding
-
Lum R., Niggemann M., and Glover J.R. Peptide and protein binding in the axial channel of Hsp104. Insights into the mechanism of protein unfolding. J. Biol. Chem. 283 (2008) 30139-30150
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 30139-30150
-
-
Lum, R.1
Niggemann, M.2
Glover, J.R.3
-
27
-
-
27144474906
-
Rebuilt AAA + motors reveal operating principles for ATP-fuelled machines
-
Martin A., Baker T.A., and Sauer R.T. Rebuilt AAA + motors reveal operating principles for ATP-fuelled machines. Nature 437 (2005) 1115-1120
-
(2005)
Nature
, vol.437
, pp. 1115-1120
-
-
Martin, A.1
Baker, T.A.2
Sauer, R.T.3
-
28
-
-
39549084936
-
Diverse pore loops of the AAA+ ClpX machine mediate unassisted and adaptor-dependent recognition of ssrA-tagged substrates
-
Martin A., Baker T.A., and Sauer R.T. Diverse pore loops of the AAA+ ClpX machine mediate unassisted and adaptor-dependent recognition of ssrA-tagged substrates. Mol. Cell 29 (2008) 441-450
-
(2008)
Mol. Cell
, vol.29
, pp. 441-450
-
-
Martin, A.1
Baker, T.A.2
Sauer, R.T.3
-
29
-
-
35348971984
-
ATPase site architecture and helicase mechanism of an archaeal MCM
-
Moreau M.J., McGeoch A.T., Lowe A.R., Itzhaki L.S., and Bell S.D. ATPase site architecture and helicase mechanism of an archaeal MCM. Mol. Cell 28 (2007) 304-314
-
(2007)
Mol. Cell
, vol.28
, pp. 304-314
-
-
Moreau, M.J.1
McGeoch, A.T.2
Lowe, A.R.3
Itzhaki, L.S.4
Bell, S.D.5
-
30
-
-
0033516473
-
Concurrent chaperone and protease activities of ClpAP and the requirement for the N-terminal ClpA ATP binding site for chaperone activity
-
Pak M., Hoskins J.R., Singh S.K., Maurizi M.R., and Wickner S. Concurrent chaperone and protease activities of ClpAP and the requirement for the N-terminal ClpA ATP binding site for chaperone activity. J. Biol. Chem. 274 (1999) 19316-19322
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 19316-19322
-
-
Pak, M.1
Hoskins, J.R.2
Singh, S.K.3
Maurizi, M.R.4
Wickner, S.5
-
31
-
-
0027981247
-
Saccharomyces cerevisiae Hsp104 protein. Purification and characterization of ATP-induced structural changes
-
Parsell D.A., Kowal A.S., and Lindquist S. Saccharomyces cerevisiae Hsp104 protein. Purification and characterization of ATP-induced structural changes. J. Biol. Chem. 269 (1994) 4480-4487
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 4480-4487
-
-
Parsell, D.A.1
Kowal, A.S.2
Lindquist, S.3
-
32
-
-
4444221565
-
UCSF chimera-a visualization system for exploratory research and analysis
-
Pettersen E.F., Goddard T.D., Huang C.C., Couch G.S., Greenblatt D.M., Meng E.C., and Ferrin T.E. UCSF chimera-a visualization system for exploratory research and analysis. J. Comput. Chem. 25 (2004) 1605-1612
-
(2004)
J. Comput. Chem.
, vol.25
, pp. 1605-1612
-
-
Pettersen, E.F.1
Goddard, T.D.2
Huang, C.C.3
Couch, G.S.4
Greenblatt, D.M.5
Meng, E.C.6
Ferrin, T.E.7
-
33
-
-
33749257470
-
Going through the motions: The ATPase cycle of p97
-
Pye V.E., Dreveny I., Briggs L.C., Sands C., Beuron F., Zhang X., and Freemont P.S. Going through the motions: The ATPase cycle of p97. J. Struct. Biol. 156 (2006) 12-28
-
(2006)
J. Struct. Biol.
, vol.156
, pp. 12-28
-
-
Pye, V.E.1
Dreveny, I.2
Briggs, L.C.3
Sands, C.4
Beuron, F.5
Zhang, X.6
Freemont, P.S.7
-
34
-
-
18744414494
-
Conformational changes of the multifunction p97 AAA ATPase during its ATPase cycle
-
Rouiller I., DeLaBarre B., May A.P., Weis W.I., Brunger A.T., Milligan R.A., and Wilson-Kubalek E.M. Conformational changes of the multifunction p97 AAA ATPase during its ATPase cycle. Nat. Struct. Biol. 9 (2002) 950-957
-
(2002)
Nat. Struct. Biol.
, vol.9
, pp. 950-957
-
-
Rouiller, I.1
DeLaBarre, B.2
May, A.P.3
Weis, W.I.4
Brunger, A.T.5
Milligan, R.A.6
Wilson-Kubalek, E.M.7
-
35
-
-
34249944932
-
Processing of proteins by the molecular chaperone Hsp104
-
Schaupp A., Marcinowski M., Grimminger V., Bosl B., and Walter S. Processing of proteins by the molecular chaperone Hsp104. J. Mol. Biol. 370 (2007) 674-686
-
(2007)
J. Mol. Biol.
, vol.370
, pp. 674-686
-
-
Schaupp, A.1
Marcinowski, M.2
Grimminger, V.3
Bosl, B.4
Walter, S.5
-
36
-
-
0032546911
-
The ATPase activity of Hsp104, effects of environmental conditions and mutations
-
Schirmer E.C., Queitsch C., Kowal A.S., Parsell D.A., and Lindquist S. The ATPase activity of Hsp104, effects of environmental conditions and mutations. J. Biol. Chem. 273 (1998) 15546-15552
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 15546-15552
-
-
Schirmer, E.C.1
Queitsch, C.2
Kowal, A.S.3
Parsell, D.A.4
Lindquist, S.5
-
37
-
-
0035970115
-
Subunit interactions influence the biochemical and biological properties of Hsp104
-
Schirmer E.C., Ware D.M., Queitsch C., Kowal A.S., and Lindquist S.L. Subunit interactions influence the biochemical and biological properties of Hsp104. Proc. Natl. Acad. Sci. USA 98 (2001) 914-919
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 914-919
-
-
Schirmer, E.C.1
Ware, D.M.2
Queitsch, C.3
Kowal, A.S.4
Lindquist, S.L.5
-
38
-
-
0034625236
-
Crystal structure of T7 gene 4 ring helicase indicates a mechanism for sequential hydrolysis of nucleotides
-
Singleton M.R., Sawaya M.R., Ellenberger T., and Wigley D.B. Crystal structure of T7 gene 4 ring helicase indicates a mechanism for sequential hydrolysis of nucleotides. Cell 101 (2000) 589-600
-
(2000)
Cell
, vol.101
, pp. 589-600
-
-
Singleton, M.R.1
Sawaya, M.R.2
Ellenberger, T.3
Wigley, D.B.4
-
39
-
-
40649098449
-
Substrate threading through the central pore of the Hsp104 chaperone as a common mechanism for protein disaggregation and prion propagation
-
Tessarz P., Mogk A., and Bukau B. Substrate threading through the central pore of the Hsp104 chaperone as a common mechanism for protein disaggregation and prion propagation. Mol. Microbiol. 68 (2008) 87-97
-
(2008)
Mol. Microbiol.
, vol.68
, pp. 87-97
-
-
Tessarz, P.1
Mogk, A.2
Bukau, B.3
-
40
-
-
0034632063
-
AAA proteins. Lords of the ring
-
Vale R.D. AAA proteins. Lords of the ring. J. Cell Biol. 150 (2000) F13-F19
-
(2000)
J. Cell Biol.
, vol.150
-
-
Vale, R.D.1
-
41
-
-
0035096082
-
Crystal structures of the HslVU peptidase-ATPase complex reveal an ATP-dependent proteolysis mechanism
-
Wang J., Song J.J., Franklin M.C., Kamtekar S., Im Y.J., Rho S.H., Seong I.S., Lee C.S., Chung C.H., and Eom S.H. Crystal structures of the HslVU peptidase-ATPase complex reveal an ATP-dependent proteolysis mechanism. Structure 9 (2001) 177-184
-
(2001)
Structure
, vol.9
, pp. 177-184
-
-
Wang, J.1
Song, J.J.2
Franklin, M.C.3
Kamtekar, S.4
Im, Y.J.5
Rho, S.H.6
Seong, I.S.7
Lee, C.S.8
Chung, C.H.9
Eom, S.H.10
-
42
-
-
8844251486
-
Thermotolerance requires refolding of aggregated proteins by substrate translocation through the central pore of ClpB
-
Weibezahn J., Tessarz P., Schlieker C., Zahn R., Maglica Z., Lee S., Zentgraf H., Weber-Ban E.U., Dougan D.A., Tsai F.T., et al. Thermotolerance requires refolding of aggregated proteins by substrate translocation through the central pore of ClpB. Cell 119 (2004) 653-665
-
(2004)
Cell
, vol.119
, pp. 653-665
-
-
Weibezahn, J.1
Tessarz, P.2
Schlieker, C.3
Zahn, R.4
Maglica, Z.5
Lee, S.6
Zentgraf, H.7
Weber-Ban, E.U.8
Dougan, D.A.9
Tsai, F.T.10
-
43
-
-
37449008520
-
Atypical AAA+ subunit packing creates an expanded cavity for disaggregation by the protein-remodeling factor Hsp104
-
Wendler P., Shorter J., Plisson C., Cashikar A.G., Lindquist S., and Saibil H.R. Atypical AAA+ subunit packing creates an expanded cavity for disaggregation by the protein-remodeling factor Hsp104. Cell 131 (2007) 1366-1377
-
(2007)
Cell
, vol.131
, pp. 1366-1377
-
-
Wendler, P.1
Shorter, J.2
Plisson, C.3
Cashikar, A.G.4
Lindquist, S.5
Saibil, H.R.6
-
44
-
-
41149169488
-
Coupling and dynamics of subunits in the hexameric AAA+ chaperone ClpB
-
Werbeck N.D., Schlee S., and Reinstein J. Coupling and dynamics of subunits in the hexameric AAA+ chaperone ClpB. J. Mol. Biol. 378 (2008) 178-190
-
(2008)
J. Mol. Biol.
, vol.378
, pp. 178-190
-
-
Werbeck, N.D.1
Schlee, S.2
Reinstein, J.3
|