-
1
-
-
84855792427
-
Cancer statistics, 2012
-
Siegel R, Naishadham D, Jemal A. Cancer statistics, 2012. CA Cancer J Clin. 2012;62(1):10-29.
-
(2012)
CA Cancer J Clin
, vol.62
, Issue.1
, pp. 10-29
-
-
Siegel, R.1
Naishadham, D.2
Jemal, A.3
-
2
-
-
84855466019
-
A phase 3 trial of bevacizumab in ovarian cancer
-
ICON7 Investigators
-
Perren TJ, Swart AM, Pfisterer J, et al; ICON7 Investigators. A phase 3 trial of bevacizumab in ovarian cancer. N Engl J Med. 2011;365(26): 2484-2496.
-
(2011)
N Engl J Med
, vol.365
, Issue.26
, pp. 2484-2496
-
-
Perren, T.J.1
Swart, A.M.2
Pfisterer, J.3
-
3
-
-
84855425106
-
Incorporation of bevacizumab in the primary treatment of ovarian cancer
-
Gynecologic Oncology Group
-
Burger RA, Brady MF, Bookman MA, et al; Gynecologic Oncology Group. Incorporation of bevacizumab in the primary treatment of ovarian cancer. New Engl J Med. 2011;365(26):2473-2483.
-
(2011)
New Engl J Med
, vol.365
, Issue.26
, pp. 2473-2483
-
-
Burger, R.A.1
Brady, M.F.2
Bookman, M.A.3
-
4
-
-
84866493383
-
AURELIA: A randomized phase III trial evaluating bevacizumab (BEV) plus chemotherapy (CT) for platinum (PT)-resistant recurrent ovarian cancer (OC)
-
(Supplement 18). Available from:, Accessed March 13, 2013, AURELIA Investigators
-
Pujade-Lauraine E, Hilpert F, Weber B, et al; AURELIA Investigators. AURELIA: a randomized phase III trial evaluating bevacizumab (BEV) plus chemotherapy (CT) for platinum (PT)-resistant recurrent ovarian cancer (OC). J Clin Oncol. 2012;30(Supplement 18). Available from: http://meeting.ascopubs.org/cgi/content/abstract/30/18_suppl/LBA5002?sid=799bb046-3aad-4937-a1ff-10b69d3f9782. Accessed March 13, 2013.
-
(2012)
J Clin Oncol
, vol.30
-
-
Pujade-Lauraine, E.1
Hilpert, F.2
Weber, B.3
-
5
-
-
84861736119
-
OCEANS: A randomized, double-blind, placebo-controlled phase III trial of chemotherapy with or without bevacizumab in patients with platinum-sensitive recurrent epithelial ovarian, primary peritoneal, or fallopian tube cancer
-
Aghajanian C, Blank SV, Goff BA, et al. OCEANS: a randomized, double-blind, placebo-controlled phase III trial of chemotherapy with or without bevacizumab in patients with platinum-sensitive recurrent epithelial ovarian, primary peritoneal, or fallopian tube cancer. J Clin Oncol. 2012;30(17):2039-2045.
-
(2012)
J Clin Oncol
, vol.30
, Issue.17
, pp. 2039-2045
-
-
Aghajanian, C.1
Blank, S.V.2
Goff, B.A.3
-
6
-
-
79955828984
-
Immune therapy for ovarian cancer: Promise and pitfalls
-
Thibodeaux SR, Curiel TJ. Immune therapy for ovarian cancer: promise and pitfalls. Int Rev Immunol. 2011;30(2-3):102-119.
-
(2011)
Int Rev Immunol
, vol.30
, Issue.2-3
, pp. 102-119
-
-
Thibodeaux, S.R.1
Curiel, T.J.2
-
7
-
-
42949105127
-
Immunologic and clinical effects of antibody blockade of cytotoxic T lymphocyte-associated antigen 4 in previously vaccinated cancer patients
-
Hodi FS, Butler M, Oble DA, et al. Immunologic and clinical effects of antibody blockade of cytotoxic T lymphocyte-associated antigen 4 in previously vaccinated cancer patients. Proc Natl Acad Sci U S A. 2008;105(8):3005-3010.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, Issue.8
, pp. 3005-3010
-
-
Hodi, F.S.1
Butler, M.2
Oble, D.A.3
-
8
-
-
0344341626
-
Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and ovarian carcinoma patients
-
Hodi FS, Mihm MC, Soiffer RJ, et al. Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and ovarian carcinoma patients. Proc Natl Acad Sci U S A. 2003;100(8):4712-4717.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, Issue.8
, pp. 4712-4717
-
-
Hodi, F.S.1
Mihm, M.C.2
Soiffer, R.J.3
-
9
-
-
9844256432
-
Comparison of toxicity and survival following intraperitoneal recombinant interleukin-2 for persistent ovarian cancer after platinum: Twenty-four-hour versus 7-day infusion
-
Edwards RP, Gooding W, Lembersky BC, et al. Comparison of toxicity and survival following intraperitoneal recombinant interleukin-2 for persistent ovarian cancer after platinum: twenty-four-hour versus 7-day infusion. J Clin Oncol. 1997;15(11):3399-3407.
-
(1997)
J Clin Oncol
, vol.15
, Issue.11
, pp. 3399-3407
-
-
Edwards, R.P.1
Gooding, W.2
Lembersky, B.C.3
-
10
-
-
71849090003
-
A phase II trial of intraperitoneal interleukin-2 in patients with platinum-resistant or platinum-refractory ovarian cancer
-
Vlad AM, Budiu RA, Lenzner DE, et al. A phase II trial of intraperitoneal interleukin-2 in patients with platinum-resistant or platinum-refractory ovarian cancer. Cancer Immunol Immunother. 2010;59(2):293-301.
-
(2010)
Cancer Immunol Immunother
, vol.59
, Issue.2
, pp. 293-301
-
-
Vlad, A.M.1
Budiu, R.A.2
Lenzner, D.E.3
-
11
-
-
65249173447
-
Adoptive cell therapy for the treatment of patients with metastatic melanoma
-
Rosenberg SA, Dudley ME. Adoptive cell therapy for the treatment of patients with metastatic melanoma. Curr Opin Immunol. 2009; 21(2):233-240.
-
(2009)
Curr Opin Immunol
, vol.21
, Issue.2
, pp. 233-240
-
-
Rosenberg, S.A.1
Dudley, M.E.2
-
12
-
-
79959838081
-
Integrated genomic analyses of ovarian carcinoma
-
Cancer Genome Atlas Research Network
-
Cancer Genome Atlas Research Network. Integrated genomic analyses of ovarian carcinoma. Nature. 2011;474(7353):609-615.
-
(2011)
Nature
, vol.474
, Issue.7353
, pp. 609-615
-
-
-
13
-
-
77954866765
-
Poly(ADP-ribosyl)ation polymerases: Mechanism and new target of anticancer therapy
-
Heitz F, Harter P, Ewald-Riegler N, Papsdorf M, Kommoss S, du Bois A. Poly(ADP-ribosyl)ation polymerases: mechanism and new target of anticancer therapy. Expert Rev Anticancer Ther. 2010;10(7): 1125-1136.
-
(2010)
Expert Rev Anticancer Ther
, vol.10
, Issue.7
, pp. 1125-1136
-
-
Heitz, F.1
Harter, P.2
Ewald-Riegler, N.3
Papsdorf, M.4
Kommoss, S.5
du Bois, A.6
-
14
-
-
84865519032
-
Poly (ADP-ribose) polymerase inhibitors: On the horizon of tailored and personalized therapies for epithelial ovarian cancer
-
Ratner ES, Sartorelli AC, Lin ZP. Poly (ADP-ribose) polymerase inhibitors: on the horizon of tailored and personalized therapies for epithelial ovarian cancer. Curr Opin Oncol. 2012;24(5):564-571.
-
(2012)
Curr Opin Oncol
, vol.24
, Issue.5
, pp. 564-571
-
-
Ratner, E.S.1
Sartorelli, A.C.2
Lin, Z.P.3
-
15
-
-
77955887094
-
PRECEDENT: A randomized phase II trial comparing EC145 and pegylated liposomal doxorubicin (PLD) in combination, versus PLD alone, in subjects with platinum-resistant ovarian cance
-
(Supplement 18). Available from, Accessed March 13, 2013
-
Naumann RW, Symanowski JT, Ghamande SA, et al. PRECEDENT: a randomized phase II trial comparing EC145 and pegylated liposomal doxorubicin (PLD) in combination, versus PLD alone, in subjects with platinum-resistant ovarian cancer. J Clin Oncol. 2010;28(Supplement 18). Available from: http://meeting.ascopubs.org/cgi/content/abstract/28/18_suppl/LBA5012b. Accessed March 13, 2013.
-
(2010)
J Clin Oncol
, vol.28
-
-
Naumann, R.W.1
Symanowski, J.T.2
Ghamande, S.A.3
-
16
-
-
84865306252
-
BRCA1 and HSP90 cooperate in homologous and non-homologous DNA double-strand-break repair and G2/M checkpoint activation
-
Stecklein SR, Kumaraswamy E, Behbod F, et al. BRCA1 and HSP90 cooperate in homologous and non-homologous DNA double-strand-break repair and G2/M checkpoint activation. Proc Natl Acad Sci U S A. 2012;109(34):13650-13655.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, Issue.34
, pp. 13650-13655
-
-
Stecklein, S.R.1
Kumaraswamy, E.2
Behbod, F.3
-
17
-
-
84879041952
-
A phase II study of RO4929097 (RO), a gamma-secretase inhibitor, in advanced platinum (Pt)-resistant (R) ovarian cancer (OC): A study of the PMH, Chicago, and California phase II consortia
-
Available from, Accessed March 13
-
Diaz-Padilla I, Clarke B, Hirte H, et al. A phase II study of RO4929097 (RO), a gamma-secretase inhibitor, in advanced platinum (Pt)-resistant (R) ovarian cancer (OC): a study of the PMH, Chicago, and California phase II consortia. J Clin Oncol. 2012;30 Suppl. Available from: https://meetinglibrary.asco.org/content/94913-114. Accessed March 13, 2013.
-
(2012)
J Clin Oncol
, vol.30
, Issue.SUPPL.
-
-
Diaz-Padilla, I.1
Clarke, B.2
Hirte, H.3
-
18
-
-
84879047160
-
Phase I/II study of weekly paclitaxel with or without MLN8237 (alisertib), an investigational aurora A kinase inhibitor, in patients with recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer (OC), or breast cancer (BrC): Phase I results
-
Available from, Accessed March 13, 2013
-
Falchook GS, Goff BA, Kurzrock R, et al. Phase I/II study of weekly paclitaxel with or without MLN8237 (alisertib), an investigational aurora A kinase inhibitor, in patients with recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer (OC), or breast cancer (BrC): phase I results. J Clin Oncol. 2012;30 Suppl. Available from: http://meetinglibrary.asco.org/content/96468-114. Accessed March 13, 2013.
-
(2012)
J Clin Oncol
, vol.30
-
-
Falchook, G.S.1
Goff, B.A.2
Kurzrock, R.3
-
19
-
-
84860346314
-
Innate immunity's path to the Nobel Prize 2011 and beyond
-
Wagner H. Innate immunity's path to the Nobel Prize 2011 and beyond. Eur J Immunol. 2012;42(5):1089-1092.
-
(2012)
Eur J Immunol
, vol.42
, Issue.5
, pp. 1089-1092
-
-
Wagner, H.1
-
21
-
-
0023931873
-
Lymphocytes infiltrating human ovarian tumors. I. Role of Leu-19 (NKH1)-positive recombinant IL-2-activated cultures of lymphocytes infiltrating human ovarian tumors
-
Heo DS, Whiteside TL, Kanbour A, Herberman RB. Lymphocytes infiltrating human ovarian tumors. I. Role of Leu-19 (NKH1)-positive recombinant IL-2-activated cultures of lymphocytes infiltrating human ovarian tumors. J Immunol. 1988;140(11):4042-4049.
-
(1988)
J Immunol
, vol.140
, Issue.11
, pp. 4042-4049
-
-
Heo, D.S.1
Whiteside, T.L.2
Kanbour, A.3
Herberman, R.B.4
-
22
-
-
0030944928
-
Quantitative assessment of the leukocyte infiltrate in ovarian cancer and its relationship to the expression of C-C chemokines
-
Negus RP, Stamp GW, Hadley J, Balkwill FR. Quantitative assessment of the leukocyte infiltrate in ovarian cancer and its relationship to the expression of C-C chemokines. Am J Pathol. 1997;150(5): 1723-1734.
-
(1997)
Am J Pathol
, vol.150
, Issue.5
, pp. 1723-1734
-
-
Negus, R.P.1
Stamp, G.W.2
Hadley, J.3
Balkwill, F.R.4
-
23
-
-
0037448353
-
Intratumoral T cells, recurrence, and survival in epithelial ovarian cancer
-
Zhang L, Conejo-Garcia JR, Katsaros D, et al. Intratumoral T cells, recurrence, and survival in epithelial ovarian cancer. N Engl J Med. 2003;348(3):203-213.
-
(2003)
N Engl J Med
, vol.348
, Issue.3
, pp. 203-213
-
-
Zhang, L.1
Conejo-Garcia, J.R.2
Katsaros, D.3
-
24
-
-
29444442811
-
Intraepithelial CD8+ tumor-infiltrating lymphocytes and a high CD8+/regulatory T cell ratio are associated with favorable prognosis in ovarian cancer
-
Sato E, Olson SH, Ahn J, et al. Intraepithelial CD8+ tumor-infiltrating lymphocytes and a high CD8+/regulatory T cell ratio are associated with favorable prognosis in ovarian cancer. Proc Natl Acad Sci U S A. 2005;102(51):18538-18543.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, Issue.51
, pp. 18538-18543
-
-
Sato, E.1
Olson, S.H.2
Ahn, J.3
-
25
-
-
70349750194
-
In situ stimulation of CD40 and Toll-like receptor 3 transforms ovarian cancer-infiltrating dendritic cells from immunosuppressive to immunostimulatory cells
-
Scarlett UK, Cubillos-Ruiz JR, Nesbeth YC, et al. In situ stimulation of CD40 and Toll-like receptor 3 transforms ovarian cancer-infiltrating dendritic cells from immunosuppressive to immunostimulatory cells. Cancer Res. 2009;69(18):7329-7337.
-
(2009)
Cancer Res
, vol.69
, Issue.18
, pp. 7329-7337
-
-
Scarlett, U.K.1
Cubillos-Ruiz, J.R.2
Nesbeth, Y.C.3
-
26
-
-
84867503094
-
Plasmacytoid dendritic cells promote immunosuppression in ovarian cancer via ICOS costimulation of Foxp3(+) T-regulatory cells
-
Conrad C, Gregorio J, Wang YH, et al. Plasmacytoid dendritic cells promote immunosuppression in ovarian cancer via ICOS costimulation of Foxp3(+) T-regulatory cells. Cancer Res. 2012;72(20):5240-5249.
-
(2012)
Cancer Res
, vol.72
, Issue.20
, pp. 5240-5249
-
-
Conrad, C.1
Gregorio, J.2
Wang, Y.H.3
-
27
-
-
84872872011
-
Dynamics of T-cell infiltration during the course of ovarian cancer: The gradual shift from a Th17 effector cell response to a predominant infiltration by regulatory T-cells
-
Fialová A, Partlová S, Sojka L, et al. Dynamics of T-cell infiltration during the course of ovarian cancer: the gradual shift from a Th17 effector cell response to a predominant infiltration by regulatory T-cells. Int J Cancer. 2013;132(5):1070-1090.
-
(2013)
Int J Cancer
, vol.132
, Issue.5
, pp. 1070-1090
-
-
Fialová, A.1
Partlová, S.2
Sojka, L.3
-
28
-
-
84863924314
-
Regulatory T-cell modulation using cyclophosphamide in vaccine approaches: A current perspective
-
Le DT, Jaffee EM. Regulatory T-cell modulation using cyclophosphamide in vaccine approaches: a current perspective. Cancer Res. 2012;72(14):3439-3444.
-
(2012)
Cancer Res
, vol.72
, Issue.14
, pp. 3439-3444
-
-
Le, D.T.1
Jaffee, E.M.2
-
29
-
-
34347250876
-
Mechanism and therapeutic reversal of immune suppression in cancer
-
Herber DL, Nagaraj S, Djeu JY, Gabrilovich DI. Mechanism and therapeutic reversal of immune suppression in cancer. Cancer Res. 2007;67(11):5067-5069.
-
(2007)
Cancer Res
, vol.67
, Issue.11
, pp. 5067-5069
-
-
Herber, D.L.1
Nagaraj, S.2
Djeu, J.Y.3
Gabrilovich, D.I.4
-
30
-
-
77953435969
-
Antitumor activity and immune response induction of a dual agonist of Toll-like receptors 7 and 8
-
Wang D, Precopio M, Lan T, et al. Antitumor activity and immune response induction of a dual agonist of Toll-like receptors 7 and 8. Mol Cancer Ther. 2010;9(6):1788-1797.
-
(2010)
Mol Cancer Ther
, vol.9
, Issue.6
, pp. 1788-1797
-
-
Wang, D.1
Precopio, M.2
Lan, T.3
-
31
-
-
50649093779
-
The use of TLR7 and TLR8 ligands for the enhancement of cancer immunotherapy
-
Smits EL, Ponsaerts P, Berneman ZN, Van Tendeloo VF. The use of TLR7 and TLR8 ligands for the enhancement of cancer immunotherapy. Oncologist. 2008;13(8):859-875.
-
(2008)
Oncologist
, vol.13
, Issue.8
, pp. 859-875
-
-
Smits, E.L.1
Ponsaerts, P.2
Berneman, Z.N.3
van Tendeloo, V.F.4
-
33
-
-
4644237613
-
Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival
-
Curiel TJ, Coukos G, Zou L, et al. Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Nat Med. 2004;10(9):942-949.
-
(2004)
Nat Med
, vol.10
, Issue.9
, pp. 942-949
-
-
Curiel, T.J.1
Coukos, G.2
Zou, L.3
-
34
-
-
0038273853
-
Blockade of B7-H1 improves myeloid dendritic cell-mediated antitumor immunity
-
Curiel TJ, Wei S, Dong H, et al. Blockade of B7-H1 improves myeloid dendritic cell-mediated antitumor immunity. Nat Med. 2003;9(5):562-567.
-
(2003)
Nat Med
, vol.9
, Issue.5
, pp. 562-567
-
-
Curiel, T.J.1
Wei, S.2
Dong, H.3
-
35
-
-
77951260924
-
The role of pattern-recognition receptors in innate immunity: Update on Toll-like receptors
-
Kawai T, Akira S. The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. Nat Immunol. 2010;11(5): 373-384.
-
(2010)
Nat Immunol
, vol.11
, Issue.5
, pp. 373-384
-
-
Kawai, T.1
Akira, S.2
-
36
-
-
1542317578
-
Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8
-
Heil F, Hemmi H, Hochrein H, et al. Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8. Science. 2004; 303(5663):1526-1529.
-
(2004)
Science
, vol.303
, Issue.5663
, pp. 1526-1529
-
-
Heil, F.1
Hemmi, H.2
Hochrein, H.3
-
37
-
-
1842631428
-
Recognition of single-stranded RNA viruses by Toll-like receptor 7
-
Lund JM, Alexopoulou L, Sato A, et al. Recognition of single-stranded RNA viruses by Toll-like receptor 7. Proc Natl Acad Sci U S A. 2004; 101(15):5598-5603.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, Issue.15
, pp. 5598-5603
-
-
Lund, J.M.1
Alexopoulou, L.2
Sato, A.3
-
39
-
-
34249677845
-
Therapeutic targeting of innate immunity with Toll-like receptor agonists and antagonists
-
Kanzler H, Barrat FJ, Hessel EM, Coffman RL. Therapeutic targeting of innate immunity with Toll-like receptor agonists and antagonists. Nat Med. 2007;13(5):552-559.
-
(2007)
Nat Med
, vol.13
, Issue.5
, pp. 552-559
-
-
Kanzler, H.1
Barrat, F.J.2
Hessel, E.M.3
Coffman, R.L.4
-
40
-
-
84862907802
-
VTX-2337 is a novel TLR8 agonist that activates NK cells and augments ADCC
-
Lu H, Dietsch GN, Matthews MA, et al. VTX-2337 is a novel TLR8 agonist that activates NK cells and augments ADCC. Clin Cancer Res. 2012;18(2):499-509.
-
(2012)
Clin Cancer Res
, vol.18
, Issue.2
, pp. 499-509
-
-
Lu, H.1
Dietsch, G.N.2
Matthews, M.A.3
-
41
-
-
41349095198
-
Recognition of viral single-stranded RNA by Toll-like receptors
-
Diebold SS. Recognition of viral single-stranded RNA by Toll-like receptors. Adv Drug Deliv Rev. 2008;60(7):813-823.
-
(2008)
Adv Drug Deliv Rev
, vol.60
, Issue.7
, pp. 813-823
-
-
Diebold, S.S.1
-
42
-
-
5444262511
-
Toll-like receptor control of the adaptive immune responses
-
Iwasaki A, Medzhitov R. Toll-like receptor control of the adaptive immune responses. Nat Immunol. 2004;5(10):987-995.
-
(2004)
Nat Immunol
, vol.5
, Issue.10
, pp. 987-995
-
-
Iwasaki, A.1
Medzhitov, R.2
-
43
-
-
0035955425
-
The plasticity of dendritic cell responses to pathogens and their components
-
Huang Q, Liu D, Majewski P, et al. The plasticity of dendritic cell responses to pathogens and their components. Science. 2001;294(5543): 870-875.
-
(2001)
Science
, vol.294
, Issue.5543
, pp. 870-875
-
-
Huang, Q.1
Liu, D.2
Majewski, P.3
-
44
-
-
0037342360
-
Topical imiquimod in the treatment of metastatic melanoma to skin
-
Wolf IH, Smolle J, Binder B, Cerroni L, Richtig E, Kerl H. Topical imiquimod in the treatment of metastatic melanoma to skin. Arch Dermatol. 2003;139(3):273-276.
-
(2003)
Arch Dermatol
, vol.139
, Issue.3
, pp. 273-276
-
-
Wolf, I.H.1
Smolle, J.2
Binder, B.3
Cerroni, L.4
Richtig, E.5
Kerl, H.6
-
45
-
-
13444257992
-
Imiquimod is a strong inhibitor of tumor cell-induced angiogenesis
-
Majewski S, Marczak M, Mlynarczyk B, Benninghoff B, Jablonska S. Imiquimod is a strong inhibitor of tumor cell-induced angiogenesis. Int J Dermatol. 2005;44(1):14-19.
-
(2005)
Int J Dermatol
, vol.44
, Issue.1
, pp. 14-19
-
-
Majewski, S.1
Marczak, M.2
Mlynarczyk, B.3
Benninghoff, B.4
Jablonska, S.5
-
46
-
-
17444394323
-
Dosing with 5% imiquimod cream 3 times per week for the treatment of actinic keratosis: Results of two phase 3, randomized, double-blind, parallel-group, vehicle-controlled trials
-
Korman N, Moy R, Ling M, et al. Dosing with 5% imiquimod cream 3 times per week for the treatment of actinic keratosis: results of two phase 3, randomized, double-blind, parallel-group, vehicle-controlled trials. Arch Dermatol. 2005;141(4):467-473.
-
(2005)
Arch Dermatol
, vol.141
, Issue.4
, pp. 467-473
-
-
Korman, N.1
Moy, R.2
Ling, M.3
-
47
-
-
78650300359
-
Phase I trial of a Toll-like receptor 9 agonist, PF-3512676 (CPG 7909), in patients with treatment-refractory, cutaneous T-cell lymphoma
-
Kim YH, Girardi M, Duvic M, et al. Phase I trial of a Toll-like receptor 9 agonist, PF-3512676 (CPG 7909), in patients with treatment-refractory, cutaneous T-cell lymphoma. J Am Acad Dermatol. 2010;63(6):975-983.
-
(2010)
J Am Acad Dermatol
, vol.63
, Issue.6
, pp. 975-983
-
-
Kim, Y.H.1
Girardi, M.2
Duvic, M.3
-
48
-
-
84863393261
-
Phase I clinical trial of CpG oligonucleotide 7909 (PF-03512676) in patients with previously treated chronic lymphocytic leukemia
-
Zent CS, Smith BJ, Ballas ZK, et al. Phase I clinical trial of CpG oligonucleotide 7909 (PF-03512676) in patients with previously treated chronic lymphocytic leukemia. Leuk Lymphoma. 2012;53(2):211-217.
-
(2012)
Leuk Lymphoma
, vol.53
, Issue.2
, pp. 211-217
-
-
Zent, C.S.1
Smith, B.J.2
Ballas, Z.K.3
-
49
-
-
23944509107
-
Toll-like receptor 8-mediated reversal of CD4+ regulatory T cell function
-
Peng G, Guo Z, Kiniwa Y, et al. Toll-like receptor 8-mediated reversal of CD4+ regulatory T cell function. Science. 2005;309(5739):1380-1384.
-
(2005)
Science
, vol.309
, Issue.5739
, pp. 1380-1384
-
-
Peng, G.1
Guo, Z.2
Kiniwa, Y.3
-
50
-
-
32944464648
-
Pathogen recognition and innate immunity
-
Akira S, Uematsu S, Takeuchi O. Pathogen recognition and innate immunity. Cell. 2006;124(4):783-801.
-
(2006)
Cell
, vol.124
, Issue.4
, pp. 783-801
-
-
Akira, S.1
Uematsu, S.2
Takeuchi, O.3
-
51
-
-
33745241135
-
Distinct indirect pathways govern human NK-cell activation by TLR-7 and TLR-8 agonists
-
Gorski KS, Waller EL, Bjornton-Severson J, et al. Distinct indirect pathways govern human NK-cell activation by TLR-7 and TLR-8 agonists. Int Immunol. 2006;18(7):1115-1126.
-
(2006)
Int Immunol
, vol.18
, Issue.7
, pp. 1115-1126
-
-
Gorski, K.S.1
Waller, E.L.2
Bjornton-Severson, J.3
-
52
-
-
70450200218
-
Cancer immunotherapeutic potential of novel small molecule TLR7 and TLR8 agonists
-
Hamm S, Rath S, Michel S, Baumgartner R. Cancer immunotherapeutic potential of novel small molecule TLR7 and TLR8 agonists. J Immunotoxicol. 2009;6(4):257-265.
-
(2009)
J Immunotoxicol
, vol.6
, Issue.4
, pp. 257-265
-
-
Hamm, S.1
Rath, S.2
Michel, S.3
Baumgartner, R.4
-
53
-
-
67649644553
-
Toll-like receptor expression in normal ovary and ovarian tumors
-
Zhou M, McFarland-Mancini MM, Funk HM, Husseinzadeh N, Mounajjed T, Drew AF. Toll-like receptor expression in normal ovary and ovarian tumors. Cancer Immunol Immunother. 2009;58(9):1375-1385.
-
(2009)
Cancer Immunol Immunother
, vol.58
, Issue.9
, pp. 1375-1385
-
-
Zhou, M.1
McFarland-Mancini, M.M.2
Funk, H.M.3
Husseinzadeh, N.4
Mounajjed, T.5
Drew, A.F.6
-
54
-
-
29144530630
-
Caspase-dependent immunogenicity of doxorubicin-induced tumor cell death
-
Casares N, Pequignot MO, Tesniere A, et al. Caspase-dependent immunogenicity of doxorubicin-induced tumor cell death. J Exp Med. 2005;202(12):1691-1701.
-
(2005)
J Exp Med
, vol.202
, Issue.12
, pp. 1691-1701
-
-
Casares, N.1
Pequignot, M.O.2
Tesniere, A.3
-
55
-
-
33846057130
-
Calreticulin exposure dictates the immunogenicity of cancer cell death
-
Obeid M, Tesniere A, Ghiringhelli F, et al. Calreticulin exposure dictates the immunogenicity of cancer cell death. Nat Med. 2007;13(1): 54-61.
-
(2007)
Nat Med
, vol.13
, Issue.1
, pp. 54-61
-
-
Obeid, M.1
Tesniere, A.2
Ghiringhelli, F.3
-
56
-
-
81155127754
-
Phase I clinical trial of VTX-2337, a selective toll-like receptor 8 (TLR8) agonist, in patients with advanced solid tumors
-
Available from, Accessed March 13, 2013
-
Cohen PA, Northfelt DW, Weiss GJ, et al. Phase I clinical trial of VTX-2337, a selective toll-like receptor 8 (TLR8) agonist, in patients with advanced solid tumors. J Clin Oncol. 2011;29(Suppl 15). Available from: http://meeting.ascopubs.org/cgi/content/short/29/15_suppl/2537?rss=1. Accessed March 13, 2013.
-
(2011)
J Clin Oncol
, vol.29
, Issue.SUPPL. 15
-
-
Cohen, P.A.1
Northfelt, D.W.2
Weiss, G.J.3
-
57
-
-
84879048742
-
-
Clinical Oncology Group. A phase I study of VTX-2337 (IND #78,416) in combination with Doxil® (NSC# 712227) in patients with recurrent or persistent epithelial ovarian, fallopian tube or primary peritoneal cancer. In: ClinicalTrials.gov [website on the Internet]. Bethesda, MD: US National Library of Medicine, [updated June 15, 2012]. Available from, Accessed March 13, 2013
-
Clinical Oncology Group. A phase I study of VTX-2337 (IND #78,416) in combination with Doxil® (NSC# 712227) in patients with recurrent or persistent epithelial ovarian, fallopian tube or primary peritoneal cancer. In: ClinicalTrials.gov [website on the Internet]. Bethesda, MD: US National Library of Medicine; 2011 [updated June 15, 2012]. Available from: http://clinicaltrials.gov/show/NCT01294293.NLM identifier:NCT01294293. Accessed March 13, 2013.
-
(2011)
-
-
-
58
-
-
84879036637
-
-
Clinical Oncology Group. A randomized, double-blind, placebo-controlled phase II Study of VTX-2337 in combination with pegylated liposomal doxorubicin (PLD) in patients with recurrent or persistent epithelial ovarian, fallopian tube or primary peritoneal cancer. In: ClinicalTrials.gov [website on the Internet]. Bethesda, MD: US National Library of Medicine, [updated March 7, 2013]. Available from, Accessed March 13, 2013
-
Clinical Oncology Group. A randomized, double-blind, placebo-controlled phase II Study of VTX-2337 in combination with pegylated liposomal doxorubicin (PLD) in patients with recurrent or persistent epithelial ovarian, fallopian tube or primary peritoneal cancer. In: ClinicalTrials.gov [website on the Internet]. Bethesda, MD: US National Library of Medicine; 2012 [updated March 7, 2013]. Available from: http://clinicaltrials.gov/show/NCT01666444.NLMidentifier:NCT01666444. Accessed March 13, 2013.
-
(2012)
-
-
|