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Volumn 21, Issue 14, 2013, Pages 4426-4431

Anti-leishmanial evaluation of C2-aryl quinolines: Mechanistic insight on bioenergetics and sterol biosynthetic pathway of Leishmania braziliensis

(11) Bompart, Daznia a Núñez Durán, Jorge a Rodríguez, Daniel a Kouznetsov, Vladimir V b Meléndez Gómez, Carlos M b Sojo, Felipe a Arvelo, Francisco a,c Visbal, Gonzalo d Alvarez, Alvaro d Serrano Martín, Xenón a García Marchán, Yael a

a Fundacion Instituto de Estudios Avanzados IDEA (Venezuela)

b UNIVERSIDAD INDUSTRIAL DE SANTANDER (Colombia)

c FACULTAD DE CIENCIAS (Venezuela)

d INSTITUTO VENEZOLANO DE INVESTIGACIONES CIENTÍFICAS (Venezuela)

Author keywords

C2 aryl substituted quinolines; Chemotherapy; L. braziliensis; Parasite bioenergetics; Sterol biosynthetic pathway

Indexed keywords

5,7 DIETHYL 2 PHENYLQUINOLINE; 6 ETHYL 2 PHENYLQUINOLINE; ANTIPARASITIC AGENT; ERGOSTEROL; MILTEFOSINE; QUINOLINE DERIVED ANTIINFECTIVE AGENT; UNCLASSIFIED DRUG;

ACIDOCALCISOME; ALKALINIZATION; ANTILEISHMANIAL ACTIVITY; ARTICLE; BIOENERGY; CELL COUNT; CELL ORGANELLE; CELL VIABILITY; CELLULAR PARAMETERS; CONTROLLED STUDY; DRUG ACTIVITY; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; LEISHMANIA BRAZILIENSIS; MACROPHAGE; MITOCHONDRIAL ELECTROCHEMICAL POTENTIAL; NONHUMAN; PROMASTIGOTE; STEROL SYNTHESIS;

ANIMALS; ANTIPARASITIC AGENTS; ENERGY METABOLISM; LEISHMANIA BRAZILIENSIS; LIFE CYCLE STAGES; MACROPHAGES; MOLECULAR STRUCTURE; QUINOLINES;

ALNUS; LEISHMANIA BRAZILIENSIS; MAMMALIA;

EID: 84879006952 PISSN: 09680896 EISSN: 14643391 Source Type: Journal
DOI: 10.1016/j.bmc.2013.04.063 Document Type: Article

Times cited : (25)

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