Synthesis and evaluation of isosteres of N-methyl indolo[3,2-b]-quinoline (cryptolepine) as new antiinfective agents

Bioorganic and Medicinal Chemistry

Volumn 15, Issue 2, 2007, Pages 686-695

  Zhu, Xue Y ^a   Mardenborough, Leroy G ^a   Li, Shouming ^a   Khan, Abdul ^a   Zhang, Wang ^a   Fan, Pincheng ^a   Jacob, Melissa ^b   Khan, Shabana ^b   Walker, Larry ^b   Ablordeppey, Seth Y ^a  

^a FLORIDA A AND M UNIVERSITY   (United States)

^b UNIVERSITY OF MISSISSIPPI   (United States)

Author keywords

Antibacterial; Antifungal; Antiinfective; Antileishmanial; Antimalarial; Benzofuroquinoline; Benzothienoquinoline; Cryptolepine analog; Fungal inhibition; Fungistatic agents; Indenoquinoline; Indoloquinoline; Isostere

Indexed keywords

ANTIINFECTIVE AGENT; QUINOLINE DERIVATIVE;

ARTICLE; ASPERGILLUS FUMIGATUS; CANDIDA ALBICANS; CRYPTOCOCCUS NEOFORMANS; CYTOTOXICITY; DRUG ACTIVITY; DRUG SYNTHESIS; EVALUATION; NONHUMAN;

ALKALOIDS; ANIMALS; ANTI-INFECTIVE AGENTS; ANTIMALARIALS; ANTIPARASITIC AGENTS; BACTERIA; CELL LINE; CELL SURVIVAL; CERCOPITHECUS AETHIOPS; CHEMISTRY, PHYSICAL; FUNGI; HUMANS; INDICATORS AND REAGENTS; INDOLES; ISOMERISM; LEISHMANIA DONOVANI; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MICROBIAL SENSITIVITY TESTS; PLASMODIUM FALCIPARUM; QUINOLINES; STRUCTURE-ACTIVITY RELATIONSHIP; VERO CELLS;

EID: 33845296973     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2006.10.062     Document Type: Article

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