Trim proteins as ring finger E3 ubiquitin ligases

Advances in Experimental Medicine and Biology

Volumn 770, Issue , 2012, Pages 27-37

  Ikeda, Kazuhiro ^a   Inoue, Satoshi ^a,b  

^a SAITAMA MEDICAL UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN EFP; REGULATOR PROTEIN; RING FINGER PROTEIN; TRIPARTITE MOTIF PROTEIN; TRIPARTITE MOTIF PROTEIN 11; TRIPARTITE MOTIF PROTEIN 18; TRIPARTITE MOTIF PROTEIN 21; TRIPARTITE MOTIF PROTEIN 32; TRIPARTITE MOTIF PROTEIN 5; TRIPARTITE MOTIF PROTEIN 63; UBIQUITIN; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; UBIQUITIN PROTEIN LIGASE;

ARTICLE; ISGYLATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN MODIFICATION; PROTEIN PROTEIN INTERACTION; UBIQUITINATION; ANIMAL; BIOLOGICAL MODEL; CHEMISTRY; HUMAN; METABOLISM; PROTEIN MOTIF; REVIEW; RING FINGER MOTIF;

AMINO ACID MOTIFS; ANIMALS; HUMANS; MODELS, BIOLOGICAL; RING FINGER DOMAINS; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

MLCS; MLOWN;

EID: 84878906997     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4614-5398-7_3     Document Type: Article

References (67)

1. I. Borden KL, Boddy MN, Lally Jet al. The solution structure of the RING finger domain from the acute promyeloc ytic leukaemia proto-oncoprotein PML. EMBO J 1995; 14(7) :1532-1 541.
2. Barlow PN, Luisi B, Milner A, et al. Structure of the C3HC4 domain by IH-nuclear magnet ic resonance spectroscopy. A new struc tural class of zinc-finger. J Mol Bioi 1994; 237(2) :201-211.
3. Reymond A, Meron i G, Fanto zzi A, et al. The tripartite motif famil y identifies cell compartmen ts. EMBO J 2001; 20(9):2140-2151.
4. Reddy BA, Etkin LD, Freemont PS.A novel zinc finger co iled-coil domain in a family ofnucle ar proteins. Trends Biochem Sci 1992; 17(9):344-345 .
5. Kakizuka A, Miller WH Jr, Umesono K, et al. Chromosomal translocation t(15;17) in human acute promyelocytic leuk emia fuses RAR alpha with a nove l putative tran scripti on factor, PML. Cell 1991; 66(4):663-674.
6. de The H, Lavau C, Marchio A, et al. The PML-RAR alpha fusio n mRNA generat ed by the t(l5; 17) translocation in acu te promyclocyti c leukemia encodes a func tionally altered RAR. Cell 1991; 66(4) :675-684.
7. Goddard AD, Borrow J, Freerno nt PS, et al. Characterization ofazinc finger gene disrupted by the t(15;17) in acute promyelocytic leukemia . Scie nce 1991; 254(5036):1371-1374.
8. Miki Y, Swensen J, Shattuck-Eidens D, et al. A stro ng candidate for the breas t and ovarian cancer suscepti bility gene BRCA I. Scie nce 1994; 266(5 182):66-71.
9. Le Douarin B, Zec he l C, Garn ier JM, et al. The N-terminal part of T1F I, a put ative mediator of the ligand-depend ent activation functio n (AF -2) of nucle ar rece ptors, is fused to B-raf in the oncoge nic protein Tl8. EMBO J 1995; 14(9):2020-2033.
10. Takahashi R, Devera ux Q, Tamm I, et al. A single BIR domain ofXIAP sufficient for inhibiting caspases. J BioI Chem 1998; 273 (14):7787-7790.
11. Hershko A, Ciechanover A. The ubiquitin system. Annu Rev Biochem 1998; 67:425 -479.
12. Joazeiro CA, Wing SS, Huang H, et al. The tyrosin e kinase negative regu lator c-Cbl as a RING -type, E2-dependent ubiquitin-prot ein ligase. Science 1999; 286(5 438):309-3 12.
13. Lor ick KL, Jensen JP, Fang S, et al. RING fingers mediate ubiquitin-conju gating enzyme (E2)-dependent ubiquitination. Proc Natl Aca d Sci USA 1999; 96(20):11364-1 1369.
14. Urano T, Saito T, Tsu kui T, et al. Efp targets 14-3-3 sigma for proteo lysis and promotes breas t tum our growth. Nature 2002; 417(6891):871-875 .
15. Zha ng Y, Xiong Y. Control of p53 ubiquitination and nuclear ex port by MDM2 and ARF. Ce ll Growth Differ 2001; 12(4): 175-186.
16. Seol JI-I, Feldman RM, Zac hariae W, et al. Cdc53 /cu llin and the esse ntial Hrtl RING-H2 subunit ofSCF defineaubiq uitin ligase modul e that activates the E2 enzymeCdc34.Genes Dev 1999; 13(12):1614-1626.
17. Pickart CM. Targeting of substrates to the 26S proteasome. FASEB J 1997; II (13) : I055 -1066 .
18. Hicke L. Gettin ' down with ubiquitin: turning off cell-s urface receptors, transporters and chann els. Tre nds Ce ll Bioi 1999; 9(3): I07-112.
19. StrousGJ,Govers R.The ubiquitin-proteasome system and endocytosis.J Cell Sci 1999; 112(10): 1417-1 423
20. Spence J, Sadis S, Haas AL, et al. A ubiquitin mut ant with spec ific defects in DNA repair and multi ubiquitination. Mol Cell Bioi 1995; 15(3):1265-1273.
21. Amason T, Ell isonMJ. Stress resis tance in Saccharomyces cerevisiae is strongly correla ted with assembly of a novel type of multiubi quiti n chain. Mol Cell Bioi 1994; 14(12):7876-7883.
22. Spence J, Ga li RR, Dittmar G, et al. Cell cycle -regu lated modification of the ribosome by a variant multi ubiquitin chain. Cell 2000; 102 (1):67 -76 .
23. Deng L, Wang C, Spencer E et al. Activation of the IkB kinase complex by TRAF6 requi res a dimer ic ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain. Ce ll 2000; 103(2):351-361.
24. Inoue S, Orimo A, Ilosoi T, et al. Genomic binding-site cloni ng reveals an estroge n-res ponsive gene that enc odes a RING finger prot ein. Proc Nat! Aca d Sci USA 1993 ; 90(23): 111 17-1112 1.
25. Orimo A, Inoue S, Ikeda K, et al. Molecular cloni ng, struc ture and express ion of mouse estroge nresponsive finger protein Efp. Co-localization with estrogen receptor mRNA in target organs . J Bioi Chern 1995; 270(41):24406-244 13.
26. Ikeda K, Orimo A, Higas hi Yet al. Efp as a primary estrogen-responsive gene in hum an breast cancer. FEBS Lett 2000; 472(1) :9-13.
27. Orimo A, Inoue S, Minowa 0, et al. Underdeveloped uterus and redu ced estrogen responsiveness in mice with disru ption of the estroge n-responsive finger protein ge ne, which is a direct target of estrogen receptor alpha. Proc Natl Acad Sci USA 1999 ; 96(2 1):12027-12032
28. Nakasato N, Ikeda K, Urano T, et al. A ubiquitin E3 ligase Efp is up-reg ulated by interferon s and conj ugated with ISGl5. Bioc hem Bio phys Res Commun 2006 ; 35 1(2):540-5 46 .
29. Blomstrom DC, Fahey D,Kutny Re t al.Molecu larcharacterization ofthe interferon -induced 15-kDa protein. Molecu lar clon ing and nucleotide and amino acid sequ ence. J Bioi Chem 1986 ; 261 (19):88 11-8816.
30. Staub O. Ubiquitylation and isgylation: overlapping enzymatic cascades do the j ob. Sci STKE 2004; 10: 43
31. Wong JJ, Pung YF, Sze NS, et al. HERC5 is an IFN-induced HECT-type E3 protein ligase that med iates type I IFN-i nduced ISGylation ofprotein targets . Proc NatlAcad Sci USA 2006; 103(28): 10735 -10740 .
32. Zo u W, Wang J, Zhang DE. Negative regulation of ISG I5 E3 ligase EFP through its autoISGylation . Biochem Biophys Res Commun 2007; 354 (1):32 1-327 .
33. Loe b KR, Haas AL. The inte rferon -induci ble 15-kDa ubiquitin homolog conj ugates to intrace llular proteins. J Bioi Chem 1992; 267(11):7806-78 13.
34. Ritchie KJ, Hahn CS, Kim KI, et al. Role ofiSG 15 protease UBP43 (US PI8) in innate immunity to viral infection. Nat Med 2004; 10(12):1374-1378.
35. Okumura A, Lu G, Pitha-Row e I, et al. Innate antiviral response targets HIV-l rele ase by the induction of ubiquitin-like pro tein ISG15. Proc Natl Acad Sci USA 2006; 103(5): 1440-1445.
36. Lenschow OJ, Giannakopoulos NV, Gunn LJ, et al. Identification of interferon-stimulated gene 15 as an antiv iral molecu le dur ing Sindbis virus infection in vivo. J Viro l 2005; 79(22) :13974-13983.
37. Lenschow OJ, Lai C, Frias-Staheli Net al.lFN-stimulatedgene 15 functions as a critical antiviral molecu le aga inst influenza, herpes and Sindbis viruses . Proc Natl Acad Sci USA 2007; 104(4): 1371-1376.
38. GackMU, Shin YC, Joo CH, et al. TRIM25 RING-fi nger E3 ubiquiti n ligase is essential for RIG-I-mediated antiv iral activity. Nature 2007; 446(7138):916-920.
39. Yoneyama M, Kikuchi M, Matsumoto K, et al. Shared and unique functio ns ofthe DExD/H-box hel icases RIG-I, MDA5 and LGP2 in antiviral innate immunity. J Immunol 2005 ; 175(5):285 1-2858.
40. Poeck H, Inoue S, Ruland J, et al. RIG-I is a dual activator of Card9 and inflammasome signaling for IL-113 production upon RNA virus recog nitio n. Nat Immun ol. in press .
41. Gack MU, Albrecht RA, Urano T, et al. Influenza A virus NS I targets the ubiquitin ligase TRIM25 to evade recognition by the host vira l RNA sensor RIG-I. Cell Host Microbe 2009; 5(5):439-449 -
42. Opitz JM. G syndrome (hypertelorism with esophageal abnormality and hypospadias, or hypos padiasdysphag ia, or "Opitz-Frias" or "O pitz-G" syndrome)-pers pective in 1987 and bib liography. Am J Med Genet 1987; 28(2):275-285.
43. Robin NH, Opitz JM, Mucnke M. Opitz G/BBB syndrome: clinical comparisons offam ilies linked to Xp22 and 22q and a review of the literatur e. Am J Med Genet 1996; 62(3) :305-317.
44. Quaderi NA, Schwe iger S, Gaudenz K, et al. Opitz G/BBB syndrome, a defec t of mid line deve lopment, is due to mutations in a new RING finger gene on Xp22. Nat Genet 1997; 17(3):285-291 .
45. Gaudenz K, Roessler E, Quaderi N, et al. Opitz G/BBB syndrome in Xp22: mutations in the MID I gene clust er in the carboxy-terminal domain . Am J Hum Genet 1998; 63(3):703-7 10.
46. Jerome LA, Papaioannou VE. DiGeorge syndrome phe notype in mice mutant for the T-box gene, Tbx I. Nat Genet 2001; 27(3):286-291 .
47. Short KM, Hopwood B, Yi Z et al. MID I and MID2 homo-and hctcrodimcrise to tether the rapamycinsensitive PP2A regu latory subunit, alpha 4, to microtubules: implicatio ns for the clinical variability of X-linked Opitz GBBB syndrome and other developmenta l disorders. BMC Cell Bioi 2002; 3(1) : I.
48. Niikura T, Hashimoto Y, Tajima H, et al. A tripartite motif protein TRIM I I binds and destabilizes Humani n, a neurop rotective peptide against Alzheimer's disease -relevant insults. Eur J Neurosci 2003; 17(6): 1150-1158.
49. Sibilia J. Ro(SS -A) and anti-Ro(SS-A): an update. Rev Rhum Engl Ed 1998; 65 (1):45-57.
50. Itoh Y, Reich lin M. Autoantibodies to the RolSSA antig en are confo rmation dependent. I: Anti-60 kD antibodies are mainly directed to the native pro tein; anti-52 kD antibodies arc main ly directed to the denature d protein. Autoimmunity 1992; 14 (1):57-65
51. Takahata M, Bohgaki M, Tsukiyama T, et al. R052 func tionally interacts with IgG I and reg ulates its quality control via the ERAD system. Mollmmuno l 2008; 45(7):2045-20 54.
52. Kong I-1J, Anderson DE, Lee CII, et al. Cutting edge: autoan tigen R052 is an interferon inducible E3 ligase that ubiquitinates IRF-8 and enhances cytokine expression in macro phages . J Immuno l 2007; 179(1):26-30 .
53. Kudryashova E, Kudryashov 0, Kramerova I, et al. Trim32 is a ubiqu itin ligas e mutated in limb girdle muscu lar dystrophy type 211that binds to ske letal muscle myosi n and ubiquitinates actin. J Mol Bioi 2005; 354(2) :413-424.
54. Centner T, Yano J, Kimura E, et al. Identification of muscle speci fic ring finger proteins as potent ial reg ulators of the titin kinase domain. J Mol BioI 2001; 306 (4) :717-726.
55. Gregorio CC, Perry CN, McElhinny AS. Functio nal propert ies of the titin/connectin-associated proteins, the muscle-specific RING finger proteins (MU RFs), in striated muscle. J Muscle Res Cell Motil2005; 26(6 -8):389-400.
56. McElhi nny AS, Kakinuma K, Sorimachi H, et al. Muscl e-specific RING finger-I interacts with titin to reg ulate sarcomeric M-line and thick filament struc ture and may have nuclear functions via its interaction with glucocorticoid modulatory element binding protein-I. J Cell BioI 2002 ; 157(1):125-136.
57. Kedar V, McDo nough II, Ary R, et al. Muscle-spec ific RING finger I is a bona fide ubiqui tin ligase that degrades cardiac troponin I. Proc Nat! Acad Sci USA 2004; 101(52):18135-18140.
58. Bodine SC, Latres E, Baum hueter Set al. Identification of ubiquitin ligases required for skele ta l muscle atro phy. Science 2001; 294(55 47): 1704-1708.
59. Clarke BA, Drujan O, Willis MS, et al. The E3 ligase MuRF I degrades myosin heavy chain protein in dexa methason e-treated skeleta l muscle. Cell Metabolism 2007; 6(5) :376-385 .
60. Stremlau M, Owens CM, Perron MJ et al. The cytop lasm ic body compone nt TRIM5alpha restricts I-1 IV-1 infection in Old World monkeys . Nature 2004; 427(6977):848-853.
61. Sakuma R, Noser JA, Ohmin e S, et al. Rhesus monkey TRIM5alpha restri cts HIV-I production through rapid degradatio n of viral Gag polyprotcins. Nat Mcd 2007 ; 13(5):63 1-635.
62. Hatzi ioannou T, Perez-Caballero 0, Yang A, et al. Retrovirus resistan ce factors Ref! and Lvi are species-specific variants of TRIM5. Proc Natl Acad Sci USA 2004 ; 101(29): 10774-10779.
63. KeckesovaZ, Yline n LM, Towers GJ.The human and African green monkey TRIM5a genes encode Ref! and Lv I retrov iral restriction factor activities. Proc Natl Acad Sci USA 2004; 101(29) 10780-10785.
64. Perez-Caballero 0, Hatziioannou T, Yang A, et al. Human tripa rtite motif 5alpha domains responsible for retrovirus restrictio n act ivity and specificity. J Virol 2005 ; 79(14) :8969-8978.
65. SebastianS, LubanJ.TRIM5alpha selectively binds arestrictio n-sensitive retroviral capsid. Retrovirology 2005; 2:40.
66. Diaz-Griffero F, Li X, Javanbakht H, et al. Rapid turnover and polyubiquitylation of the retroviral restriction factor TRIM5. Viro logy 2006; 349(2):300-315.
67. Asaoka K, Ikeda K, Hishinuma T, et al. A retrovirus restriction factor TRIM5a is transcriptionally regulated by interferons . Biochem Biophys Res Commun 2005; 338(4) :1950-1956.