TRIM5α selectively binds a restriction-sensitive retroviral capsid

Retrovirology

Volumn 2, Issue , 2005, Pages

  Sebastian, Sarah ^a   Luban, Jeremy ^a  

^a College of Physicians and Surgeons ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CORE PROTEIN; GLUTATHIONE TRANSFERASE; HYBRID PROTEIN; RNA DIRECTED DNA POLYMERASE; TRIPARTITE MOTIF PROTEIN 5; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME ACTIVITY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; MOLECULAR RECOGNITION; MURINE LEUKEMIA VIRUS; NONHUMAN; PRIMATE; PROTEIN DOMAIN; RETROVIRUS; SENSITIVITY AND SPECIFICITY; VIRION; VIRUS CAPSID; VIRUS INHIBITION;

ANIMALIA; HUMAN IMMUNODEFICIENCY VIRUS 1; MIRIDAE; MURINE LEUKEMIA VIRUS; PRIMATES;

EID: 27344435418     PISSN: 17424690     EISSN: 17424690     Source Type: Journal    
DOI: 10.1186/1742-4690-2-40     Document Type: Article

References (20)

1. Stremlau M, Owens CM, Perron MJ, Kiessling M, Autissier P, Sodroski J: The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys. Nature 2004, 427(6977):848-853.
2. Sayah DM, Sokolskaja E, Berthoux L, Luban J: Cyclophilin A retrotransposition into TRIM5 explains owl monkey resistance to HIV-1. Nature 2004, 430(6999):569-573.
3. Nisole S, Lynch C, Stoye JP, Yap MW: A Trim5-cyclophilin A fusion protein found in owl monkey kidney cells can restrict HIV-1. Proc Natl Acad Sci U S A 2004, 101(36):13324-13328.
4. Berthoux L, Sebastian S, Sayah DM, Luban J: Disruption of human TRIM5alpha antiviral activity by nonhuman primate orthologues. J Virol 2005, 79(12):7883-7888.
5. Keckesova Z, Ylinen LM, Towers GJ: The human and African green monkey TRIM5alpha genes encode Ref1 and Lv1 retroviral restriction factor activities. Proc Natl Acad Sci U S A 2004, 101(29):10780-10785.
6. Hatziioannou T, Perez-Caballero D, Yang A, Cowan S, Bieniasz PD: Retrovirus resistance factors Ref1 and Lv1 are species-specific variants of TRIM5alpha. Proc Natl Acad Sci U S A 2004, 101(29):10774-10779.
7. Yap MW, Nisole S, Lynch C, Stoye JP: Trim5alpha protein restricts both HIV-1 and murine leukemia virus. Proc Natl Acad Sci U S A 2004, 101(29):10786-10791.
8. Perron MJ, Stremlau M, Song B, Ulm W, Mulligan RC, Sodroski J: TRIM5alpha mediates the postentry block to N-tropic murine leukemia viruses in human cells. Proc Natl Acad Sci U S A 2004, 101(32):11827-11832.
9. Song B, Javanbakht H, Perron M, Park do H, Stremlau M, Sodroski J: Retrovirus restriction by TRIM5alpha variants from old world and new world primates. J Virol 2005, 79(7):3930-3937.
10. Ponting C, Schultz J, Bork P: SPRY domains in ryanodine receptors (Ca(2+)-release channels). Trends Biochem Sci 1997, 22(6):193-194.
11. Yap MW, Nisole S, Stoye JP: A single amino acid change in the SPRY domain of human Trim5alpha leads to HIV-1 restriction. Curr Biol 2005, 15(1):73-78.
12. Sawyer SL, Wu LI, Emerman M, Malik HS: Positive selection of primate TRIM5alpha identifies a critical species-specific retroviral restriction domain. Proc Natl Acad Sci U S A 2005, 102(8):2832-2837.
13. Stremlau M, Perron M, Welikala S, Sodroski J: Species-Specific Variation in the B30.2(SPRY) Domain of TRIM5{alpha} Determines the Potency of Human Immunodeficiency Virus Restriction. J Virol 2005, 79(5):3139-3145.
14. Towers G, Collins M, Takeuchi Y: Abrogation of Ref1 retrovirus restriction in human cells. J Virol 2002, 76(5):2548-2550.
15. Cowan S, Hatziioannou T, Cunningham T, Muesing MA, Gottlinger HG, Bieniasz PD: Cellular inhibitors with Fvl-like activity restrict human and simian immunodeficiency virus tropism. Proc Natl Acad Sci U S A 2002, 99(18):11914-11919.
16. Towers GJ, Hatziioannou T, Cowan S, Goff SP, Luban J, Bieniasz PD: Cyclophilin A modulates the sensitivity of HIV-1 to host restriction factors. Nat Med 2003, 9(9):1138-1143.
17. Welker R, Hohenberg H, Tessmer U, Huckhagel C, Krausslich HG: Biochemical and structural analysis of isolated mature cores of human immunodeficiency virus type 1. J Virol 2000, 74(3):1168-1177.
18. Bowerman B, Brown PO, Bishop JM, Varmus HE: A nucleoprotein complex mediates the integration of retroviral DNA. Genes Dev 1989, 3(4):469-478.
19. Fassati A, Goff SP: Characterization of intracellular reverse transcription complexes of Moloney murine leukemia virus. J Virol 1999, 73(11):8919-8925.
20. Towers G, Bock M, Martin S, Takeuchi Y, Stoye JP, Danos O: A conserved mechanism of retrovirus restriction in mammals. Proc Natl Acad Sci U S A 2000, 97(22):12295-12299.