Influence of coating agents on the degradation of poly(D,L-lactic acid) nanoparticles in model digestive fluids (USP XXII)

S.T.P. Pharma Sciences

Volumn 6, Issue 3, 1996, Pages 195-202

  Landry, F B ^a   Bazile, D V ^b   Spenlehauer, G ^b   Veillard, M ^b   Kreuter, J ^a  

^a GOETHE UNIVERSITY   (Germany)

^b SANOFI   (France)

Author keywords

Albumin; Enzymatic degradation; Gastric fluid; Intestinal fluid; Nanoparticles; Poly(D,L lactic acid); Polyvinyl alcohol

Indexed keywords

ALBUMIN; PANCREATIN; POLYLACTIC ACID; POLYVINYL ALCOHOL; PROTEIN;

ARTICLE; DRUG COATING; DRUG DEGRADATION; DRUG DETERMINATION; ENZYME DEGRADATION; INTESTINE FLUID;

EID: 0029950793     PISSN: 11571489     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. DAMGE C., MICHEL C., APRAHAMIAN M and COUVREUR P. - New approach for oral administration of insulin with polyalkylcyanoacrylate nanocapsules as drug carriers. - Diabetes, 37, 246-251, 1988.
2. MAINCENT P., LE VERGE R., SADO P., COUVREUR P. and DEVISSAGUET J.P. - Disposition kinetics and oral bioavailability of vincamine-loaded polyalkyl cyanoacrylate nanoparticles - J. Pharm. Sci., 75 (10), 955-958, 1986.
3. ANDRIEU V., FESSI H., DUBRASQUET M., DEVISSAGUET J.P., PUISIEUX F. and BENITAS. - Pharmacokinetic evaluation of indomethacin nanocapsules. - Drug Des. Del., 4, 295-302, 1989.
4. JANI P.U., McCARTHY D.E. and FLORENCE A.T. - Nanospheres and microspheres uptake via Peyer's patches : observation on the rate of uptake in the rat after a single oral dose. - Int. J Pharm., 86, 239-246, 1992.
5. ELDRIDGE J.H., HAMMOND C.J. and MEULBROEK J.A. - Controlled vaccine release in the gut-associated lymphoid tissues. I. Orally administered biodegradable microspheres target the Peyer's patches. - J. Controlled Release, 11, 205-214, 1990.
6. FLORENCE A.T., JANI P.U., HALBERT G.W. and LANGRIDGE J. - Quantitation of uptake of latex microspheres from rat gastrointestinal tract. - J. Pharm. Pharmacol., 42 (Suppl.), 54P, 1990.
7. SCHINDLER A., JEFFCOAT R., KIMMEL G.L., PITT C.G., WALL M.E. and ZWEIDINGER R. - Biodegradable polymers for sustained drug delivery. - Contemporary Topics in Polymer Sciences, 2, 251-289, 1977.
8. CHU C.C. and MONCRIEF G. - An in vitro evaluation on the stability of mechanical properties of surgical suture materials in various pH conditions. - Ann. Surg., 198, 223-228, 1983.
9. MAKING K., OSHIMA H. and KONDO T - Mechanism of hydrolytic degradation of poly(L-lactide) microcapsules : effect of pH, ionic strength and buffer concentration. - J. Microenc., 3, 203-212, 1986.
10. HYON S.H., JAMSHIDI K. and IKADA Y. - Melt spining of poly-L-lactide and hydrolysis of the fiber in vitro. - Polymers as Biomaterials, 51-65, 1984.
11. WILLIAMS D.F - Enzymatic hydrolysis of polylactic acid. - Engineering in Medicine, 10, 5-7, 1981.
12. WILLIAMS D.F. and MORT E. - Enzyme-accelerated hydrolysis of polyglycolic acid. - J. Bioengineering, 1, 231-238, 1977.
13. SALTHOUSE T.N. and MATLAGA B.F. - Polyglactin 910 suture absorption and the role of cellular enzymes. - Surgery, Gynecology & Obstetrics, 142, 544-550, 1976.
14. PITT C.G., WAYNE HENDREN R. and SCHINDLER A. - The enzymatic surface erosion of aliphatic polyesters. - J. Controlled Release, 1, 3-14, 1984.
15. LANDRY F.B., BAZILE D V., SPENLEHAUER G., VEILLARD M. and KREUTER J. - Degradation of poly(D,L-lactic acid) nanoparticfes coated with albumin in model digestives fluids (USP XXII). - Biomaterials, 17, 715-723, 1996.
16. LANDRY F.B. - Degradation of poly(D,L-lactic acid) nanoparticles in artificial gastric and intestinal fluids ; in vivo uptake of the nanoparticles and of their degradation products. - Ph.D. Thesis, University of Frankfurt, 1995.
17. ANSON M.L. - The estimation of pepsin, trypsin, papain and cathepsin with hemoglobin. - J. General Physiology, 22, 79-89, 1938.
18. Lipase diagnostic kit (Procedure No. 800). - Sigma, Saint-Quentin-Fallavier.
19. LOUISOT P. - Enzymologie générale et séméiologie enzymatique. - In : Biochimie générale et médicale, structurale, métabolique, séméiologique, SIMEP, Villeurbanne, Paris, 1983, pp. 508-517.
20. KOPECEK J. and REJMANOVA P. - Enzymatically degradable bonds in synthetic polymers. - In : Controlled Drug Delivery, Vol. 1, S.D. Bruck Ed., CRC Press, Boca Raton, 1983, pp. 81-124.
21. FUKUZAKI H., YOSHIDA M., ASANO M. and KUMAKURA M. - Synthesis of copoly(D,L-lactic acid) with relatively low molecular weight and in vitro degradation. - European Polymer Journal, 25, 1019-1026, 1989.
22. TOKIWA Y., SUZUKI T. and TAKEDA K. - Hydrolysis of polyesters by Rhizopus arrhizus lipase. - Agricultural and Biological Chemistry, 50, 1323-1325, 1986.