Receptor-mediated targeting of magnetic nanoparticles using insulin as a surface ligand to prevent endocytosis

IEEE Transactions on Nanobioscience

Volumn 2, Issue 4, 2003, Pages 255-261

  Gupta, Ajay Kumar ^a   Berry, Catherine ^a   Gupta, Mona ^a   Curtis, Adam ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

Biological cells; Drug delivery systems; Magnetic materials; Nanotechnology

Indexed keywords

CELLS; INSULIN; MAGNETIC FIELD EFFECTS; MAGNETIC MATERIALS; MAGNETIC RESONANCE IMAGING; NANOTECHNOLOGY; SCANNING ELECTRON MICROSCOPY; TRANSMISSION ELECTRON MICROSCOPY;

BIOLOGICAL CELLS; CELL ADHESION ASSAY; DRUG DELIVERY SYSTEMS; ENDOCYTOSIS;

NANOSTRUCTURED MATERIALS;

BIOMATERIAL; CELL SURFACE RECEPTOR; INSULIN; LIGAND; NANOTUBE;

ARTICLE; CELL ADHESION; CELL CULTURE; CELL SIZE; CELL SURVIVAL; CHEMISTRY; CYTOLOGY; DRUG DELIVERY SYSTEM; DRUG EFFECT; ENDOCYTOSIS; EVALUATION; FIBROBLAST; HUMAN; IMMUNOMAGNETIC SEPARATION; MATERIALS TESTING; METABOLISM; METHODOLOGY; NANOTECHNOLOGY; PARTICLE SIZE; PHYSIOLOGY; SURFACE PROPERTY; ULTRASTRUCTURE;

CELL ADHESION; CELL SIZE; CELL SURVIVAL; CELLS, CULTURED; COATED MATERIALS, BIOCOMPATIBLE; DRUG DELIVERY SYSTEMS; ENDOCYTOSIS; FIBROBLASTS; HUMANS; IMMUNOMAGNETIC SEPARATION; INSULIN; LIGANDS; MATERIALS TESTING; NANOTECHNOLOGY; NANOTUBES; PARTICLE SIZE; RECEPTORS, CELL SURFACE; SURFACE PROPERTIES;

EID: 3042850553     PISSN: 15361241     EISSN: None     Source Type: Journal    
DOI: 10.1109/TNB.2003.820279     Document Type: Article

References (19)

1. R. Weissleder, A. Bogdanov, E. A. Neuwelt, and M. Papisov, "Longcirculating iron oxides for MR imaging," Adv. Drug Delivery Rev., vol. 16, pp. 321-334, 1995.
2. P. Reimer and R. Weissleder, "Development and experimental application of receptor-specific MR contrast media," Radiology, vol. 36, pp. 153-163, 1996.
3. C. Chouly, D. Pouliquen, L. Lucet, J. J. Jeune, and P. Jallet, "Development of superparamagnetic nanoparticles for MRI: Effect of particle size, charge and surface nature on biodistribution," J Microencapsulation, vol. 13, pp. 245-255, 1996.
4. P. K. Gupta and C. T. Hung, "Magnetically controlled targeted microcarrier systems," Life Sci., vol. 44, pp. 175-186, 1989.
5. Y. Zhang, N. Kohler, and M. Zhang, "Surface modification of superparamagnetic magnetite nanoparticles and their intracellular uptake," Biomaterials, vol. 23, no. 7, pp. 1553-1561, 2002.
6. O. Olsvik, T. Popovic, E. Skjerve, K. S. Cudjoe, E. Hornes, J. Ugelstad, and M. Uhlen, "Magnetic separation techniques in diagnostic microbiology," Clin. Microbiol. Rev., vol. 7, pp. 43-54, 1994.
7. T. C. Yen, W. Zhang, S. T. Ldstad, and C. Ho, "Intracellular labeling of T-cells with superparamagnetic contrast agents," Magn. Reson. Med., vol. 30, pp. 617-25, 1993.
8. R. Handgretinger, P. Lang, M. Schumm, G. Taylor, S. Neu, E. Koscielnak, D. Niethammer, and T. Klingebiel, "Isolation and transplantation of autologous peripheral CD34+ progenitor cells highly purified by magnetic-activated cell sorting," Bone Marrow Transpl., vol. 21, pp. 987-93, 1998.
9. U. Schoep, E. Marecos, R. Jain, and R. Weissleder, "Intracellular magnetic labeling of lymphocytes for in vivo trafficking studies," BioTechniques, vol. 24, pp. 642-51, 1998.
10. A. Moore, J. Basilion, E. A. Chiocca, and R. Weissleder, "Measuring transferrin receptor gene expression by NMR imaging," Biochim. Biophys. Acta., vol. 1402, pp. 239-49, 1998.
11. R. Weissleder, H. C. Cheng, A. Bogdanova, and A. Bogdanov, "Magnetically labeled cells can be detected by MR imaging," J. Magn. Reson. Imaging, vol. 7, pp. 258-63, 1997.
12. Z. M. Qian, H. Li, H. Sun, and K. Ho, "Targeted drug delivery via transferrin receptor-mediated endocytosis pathway," Pharmacological Rev., vol. 54, no. 4, pp. 561-587, 2002.
13. D. A. Lauffenburger, D. A. Lauffenburger, and J. J. Linderman, Receptors: Models for Binding, Trafficking, and Signalling. New York: Oxford Univ. Press, 1993.
14. T. Mosmann, "Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxic assay," J. Immunol. Methods, vol. 95, pp. 55-63, 1993.
15. A. K. Gupta and A. Curtis, "Lactoferrin and ceruloplasmin derivatized superparamagnetic iron oxide nanoparticles for their targeting to cell surface receptors and preventing endocytosis: Preparation, characterization and their influence on human fibroblasts in culture," FEBS Lett., 2003, submitted for publication.
16. D. Fischer, Y. X. Li, B. Ahlemeyer, J. Krieglstein, and T. Kissel, "In vitro cytotoxicity testing of polycations: Influence of polymer structure on cell viability and hemolysis," Biomaterials, vol. 24, no. 7, pp. 1121-1131, 2003.
17. N. J. Hallab, K. J. Bundy, K. O'Connor, R. Clark, and R. L. Moses, "Cell adhesion to biomaterials: Correlations between surface charge, surface roughness, adsorbed protein and cell morphology," J. Long Term Effects Med. Implants, vol. 5, no. 3, pp. 209-231, 1995.
18. R. Weissleder, D. D. Stark, B. L. Engelstad, B. R. Bacon, C. C. Compton, D. L. White, P. Jacobs, and J. Lewis, "Superparamagnetic iron oxide: Pharmacokinetics and toxicity," Am. J. Roentgenol., vol. 152, pp. 167-73, 1989.
19. R. Gagesu, J. Gruenberg, and E. Smyte, "Membrane dynamics in endocytosis: Structure-function relationship," Traffic, vol. 1, pp. 84-88, 2000.