-
1
-
-
42149161160
-
T-helper 17 cells in psoriatic plaques and additional genetic links between IL-23 and psoriasis
-
Blauvelt A. T-helper 17 cells in psoriatic plaques and additional genetic links between IL-23 and psoriasis. J Invest Dermatol 2008; 128:1064-1067.
-
(2008)
J Invest Dermatol
, vol.128
, pp. 1064-1067
-
-
Blauvelt, A.1
-
2
-
-
33846889522
-
A human interleukin-12/23 monoclonal antibody for the treatment of psoriasis
-
Krueger GG, Langley RG, Leonardi C etal. A human interleukin-12/23 monoclonal antibody for the treatment of psoriasis. N Engl J Med 2007; 356:580-592.
-
(2007)
N Engl J Med
, vol.356
, pp. 580-592
-
-
Krueger, G.G.1
Langley, R.G.2
Leonardi, C.3
-
3
-
-
13244283212
-
IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
-
Langrish CL, Chen Y, Blumenschein WM etal. IL-23 drives a pathogenic T cell population that induces autoimmune inflammation. J Exp Med 2005; 201:233-240.
-
(2005)
J Exp Med
, vol.201
, pp. 233-240
-
-
Langrish, C.L.1
Chen, Y.2
Blumenschein, W.M.3
-
4
-
-
34249079176
-
Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells
-
Acosta-Rodriguez EV, Rivino L, Geginat J etal. Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells. Nat Immunol 2007; 8:639-646.
-
(2007)
Nat Immunol
, vol.8
, pp. 639-646
-
-
Acosta-Rodriguez, E.V.1
Rivino, L.2
Geginat, J.3
-
5
-
-
39449110445
-
The link between IL-23 and Th17 cell-mediated immune pathologies
-
McGeachy MJ, Cua DJ. The link between IL-23 and Th17 cell-mediated immune pathologies. Semin Immunol 2007; 19:372-376.
-
(2007)
Semin Immunol
, vol.19
, pp. 372-376
-
-
McGeachy, M.J.1
Cua, D.J.2
-
6
-
-
67349230808
-
The IL-23/Th17 axis in the immunopathogenesis of psoriasis
-
Di Cesare A, Di Meglio P, Nestle FO. The IL-23/Th17 axis in the immunopathogenesis of psoriasis. J Invest Dermatol 2009; 129:1339-1350.
-
(2009)
J Invest Dermatol
, vol.129
, pp. 1339-1350
-
-
Di Cesare, A.1
Di Meglio, P.2
Nestle, F.O.3
-
7
-
-
39649108216
-
Safety and efficacy of ABT-874, a fully human interleukin 12/23 monoclonal antibody, in the treatment of moderate to severe chronic plaque psoriasis: results of a randomized, placebo-controlled, phase 2 trial
-
Kimball AB, Gordon KB, Langley RG, Menter A, Chartash EK, Valdes J. Safety and efficacy of ABT-874, a fully human interleukin 12/23 monoclonal antibody, in the treatment of moderate to severe chronic plaque psoriasis: results of a randomized, placebo-controlled, phase 2 trial. Arch Dermatol 2008; 144:200-207.
-
(2008)
Arch Dermatol
, vol.144
, pp. 200-207
-
-
Kimball, A.B.1
Gordon, K.B.2
Langley, R.G.3
Menter, A.4
Chartash, E.K.5
Valdes, J.6
-
8
-
-
43449111187
-
Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 76-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 1)
-
Leonardi CL, Kimball AB, Papp KA etal. Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 76-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 1). Lancet 2008; 371:1665-1674.
-
(2008)
Lancet
, vol.371
, pp. 1665-1674
-
-
Leonardi, C.L.1
Kimball, A.B.2
Papp, K.A.3
-
9
-
-
43449139402
-
Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 52-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 2)
-
Papp KA, Langley RG, Lebwohl M etal. Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 52-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 2). Lancet 2008; 371:1675-1684.
-
(2008)
Lancet
, vol.371
, pp. 1675-1684
-
-
Papp, K.A.1
Langley, R.G.2
Lebwohl, M.3
-
10
-
-
70349753261
-
Th17 cytokines stimulate CCL20 expression in keratinocytes in vitro and in vivo: implications for psoriasis pathogenesis
-
Harper EG, Guo C, Rizzo H etal. Th17 cytokines stimulate CCL20 expression in keratinocytes in vitro and in vivo: implications for psoriasis pathogenesis. J Invest Dermatol 2009; 129:2175-2183.
-
(2009)
J Invest Dermatol
, vol.129
, pp. 2175-2183
-
-
Harper, E.G.1
Guo, C.2
Rizzo, H.3
-
11
-
-
65449142556
-
Prolactin enhances basal and IL-17-induced CCL20 production by human keratinocytes
-
Kanda N, Shibata S, Tada Y, Nashiro K, Tamaki K, Watanabe S. Prolactin enhances basal and IL-17-induced CCL20 production by human keratinocytes. Eur J Immunol 2009; 39:996-1006.
-
(2009)
Eur J Immunol
, vol.39
, pp. 996-1006
-
-
Kanda, N.1
Shibata, S.2
Tada, Y.3
Nashiro, K.4
Tamaki, K.5
Watanabe, S.6
-
12
-
-
42149087160
-
Psoriasis vulgaris lesions contain discrete populations of Th1 and Th17 T cells
-
Lowes MA, Kikuchi T, Fuentes-Duculan J etal. Psoriasis vulgaris lesions contain discrete populations of Th1 and Th17 T cells. J Invest Dermatol 2008; 128:1207-1211.
-
(2008)
J Invest Dermatol
, vol.128
, pp. 1207-1211
-
-
Lowes, M.A.1
Kikuchi, T.2
Fuentes-Duculan, J.3
-
13
-
-
47249125726
-
Chronically inflamed human tissues are infiltrated by highly differentiated th17 lymphocytes
-
Pene J, Chevalier S, Preisser L etal. Chronically inflamed human tissues are infiltrated by highly differentiated th17 lymphocytes. J Immunol 2008; 180:7423-7430.
-
(2008)
J Immunol
, vol.180
, pp. 7423-7430
-
-
Pene, J.1
Chevalier, S.2
Preisser, L.3
-
14
-
-
34347237623
-
Flow cytometry-based methods for studying signaling in human CD4+CD25+FOXP3+ T regulatory cells
-
Crellin NK, Garcia RV, Levings MK. Flow cytometry-based methods for studying signaling in human CD4+CD25+FOXP3+ T regulatory cells. J Immunol Methods 2007; 324:92-104.
-
(2007)
J Immunol Methods
, vol.324
, pp. 92-104
-
-
Crellin, N.K.1
Garcia, R.V.2
Levings, M.K.3
-
15
-
-
33746338535
-
Interleukin-10-secreting type 1 regulatory T cells in rodents and humans
-
Roncarolo MG, Gregori S, Battaglia M, Bacchetta R, Fleischhauer K, Levings MK. Interleukin-10-secreting type 1 regulatory T cells in rodents and humans. Immunol Rev 2006; 212:28-50.
-
(2006)
Immunol Rev
, vol.212
, pp. 28-50
-
-
Roncarolo, M.G.1
Gregori, S.2
Battaglia, M.3
Bacchetta, R.4
Fleischhauer, K.5
Levings, M.K.6
-
16
-
-
0033738329
-
The role of different subsets of T regulatory cells in controlling autoimmunity
-
Roncarolo MG, Levings MK. The role of different subsets of T regulatory cells in controlling autoimmunity. Curr Opin Immunol 2000; 12:676-683.
-
(2000)
Curr Opin Immunol
, vol.12
, pp. 676-683
-
-
Roncarolo, M.G.1
Levings, M.K.2
-
17
-
-
2442484053
-
Naturally arising CD4+ regulatory T cells for immunologic self-tolerance and negative control of immune responses
-
Sakaguchi S. Naturally arising CD4+ regulatory T cells for immunologic self-tolerance and negative control of immune responses. Annu Rev Immunol 2004; 22:531-562.
-
(2004)
Annu Rev Immunol
, vol.22
, pp. 531-562
-
-
Sakaguchi, S.1
-
18
-
-
0347361653
-
The role of the combination of IL-2 and TGF-beta or IL-10 in the generation and function of CD4+CD25+ and CD8+ regulatory T cell subsets
-
Horwitz DA, Zheng SG, Gray JD. The role of the combination of IL-2 and TGF-beta or IL-10 in the generation and function of CD4+CD25+ and CD8+ regulatory T cell subsets. J Leukoc Biol 2003; 74:471-478.
-
(2003)
J Leukoc Biol
, vol.74
, pp. 471-478
-
-
Horwitz, D.A.1
Zheng, S.G.2
Gray, J.D.3
-
19
-
-
10844222790
-
Dysfunctional blood and target tissue CD4+CD25high regulatory T cells in psoriasis: mechanism underlying unrestrained pathogenic effector T cell proliferation
-
Sugiyama H, Gyulai R, Toichi E etal. Dysfunctional blood and target tissue CD4+CD25high regulatory T cells in psoriasis: mechanism underlying unrestrained pathogenic effector T cell proliferation. J Immunol 2005; 174:164-173.
-
(2005)
J Immunol
, vol.174
, pp. 164-173
-
-
Sugiyama, H.1
Gyulai, R.2
Toichi, E.3
-
20
-
-
80051801522
-
Foxp3+ regulatory T cells of psoriasis patients easily differentiate into IL-17A-producing cells and are found in lesional skin
-
Bovenschen HJ, van de Kerkhof PC, van Erp PE, Woestenenk R, Joosten I, Koenen HJ. Foxp3+ regulatory T cells of psoriasis patients easily differentiate into IL-17A-producing cells and are found in lesional skin. J Invest Dermatol 2011; 131:1853-1860.
-
(2011)
J Invest Dermatol
, vol.131
, pp. 1853-1860
-
-
Bovenschen, H.J.1
van de Kerkhof, P.C.2
van Erp, P.E.3
Woestenenk, R.4
Joosten, I.5
Koenen, H.J.6
-
21
-
-
77649235565
-
Increased Th17 cells are accompanied by FoxP3(+) Treg cell accumulation and correlated with psoriasis disease severity
-
Zhang L, Yang XQ, Cheng J, Hui RS, Gao TW. Increased Th17 cells are accompanied by FoxP3(+) Treg cell accumulation and correlated with psoriasis disease severity. Clin Immunol 2010; 135:108-117.
-
(2010)
Clin Immunol
, vol.135
, pp. 108-117
-
-
Zhang, L.1
Yang, X.Q.2
Cheng, J.3
Hui, R.S.4
Gao, T.W.5
-
22
-
-
58149331211
-
Psoriasis is characterized by accumulation of immunostimulatory and Th1/Th17 cell-polarizing myeloid dendritic cells
-
Zaba LC, Fuentes-Duculan J, Eungdamrong NJ etal. Psoriasis is characterized by accumulation of immunostimulatory and Th1/Th17 cell-polarizing myeloid dendritic cells. J Invest Dermatol 2009; 129:79-88.
-
(2009)
J Invest Dermatol
, vol.129
, pp. 79-88
-
-
Zaba, L.C.1
Fuentes-Duculan, J.2
Eungdamrong, N.J.3
-
23
-
-
77954143695
-
Innate IL-17-producing cells: the sentinels of the immune system
-
Cua DJ, Tato CM. Innate IL-17-producing cells: the sentinels of the immune system. Nat Rev Immunol 2010; 10:479-489.
-
(2010)
Nat Rev Immunol
, vol.10
, pp. 479-489
-
-
Cua, D.J.1
Tato, C.M.2
-
24
-
-
79959584686
-
Mast cells and neutrophils release IL-17 through extracellular trap formation in psoriasis
-
Lin AM, Rubin CJ, Khandpur R etal. Mast cells and neutrophils release IL-17 through extracellular trap formation in psoriasis. J Immunol 2011; 187:490-500.
-
(2011)
J Immunol
, vol.187
, pp. 490-500
-
-
Lin, A.M.1
Rubin, C.J.2
Khandpur, R.3
-
25
-
-
0032787816
-
Use of a mechanical dissociation device to improve standardization of flow cytometric cytokeratin DNA measurements of colon carcinomas
-
Brockhoff G, Fleischmann S, Meier A, Wachs FP, Hofstaedter F, Knuechel R. Use of a mechanical dissociation device to improve standardization of flow cytometric cytokeratin DNA measurements of colon carcinomas. Cytometry 1999; 38:184-191.
-
(1999)
Cytometry
, vol.38
, pp. 184-191
-
-
Brockhoff, G.1
Fleischmann, S.2
Meier, A.3
Wachs, F.P.4
Hofstaedter, F.5
Knuechel, R.6
-
26
-
-
0034502715
-
Flow cytometric characterization of lesional T cells in psoriasis: intracellular cytokine and surface antigen expression indicates an activated, memory/effector type 1 immunophenotype
-
Friedrich M, Krammig S, Henze M, Docke WD, Sterry W, Asadullah K. Flow cytometric characterization of lesional T cells in psoriasis: intracellular cytokine and surface antigen expression indicates an activated, memory/effector type 1 immunophenotype. Arch Dermatol Res 2000; 292:519-521.
-
(2000)
Arch Dermatol Res
, vol.292
, pp. 519-521
-
-
Friedrich, M.1
Krammig, S.2
Henze, M.3
Docke, W.D.4
Sterry, W.5
Asadullah, K.6
-
27
-
-
0028332735
-
Multiple self epitopes on the Rhesus polypeptides stimulate immunologically ignorant human T cells in vitro
-
Barker RN, Elson CJ. Multiple self epitopes on the Rhesus polypeptides stimulate immunologically ignorant human T cells in vitro. Eur J Immunol 1994; 24:1578-1582.
-
(1994)
Eur J Immunol
, vol.24
, pp. 1578-1582
-
-
Barker, R.N.1
Elson, C.J.2
-
28
-
-
85027957926
-
Interleukin-23 as a potential therapeutic target for rheumatoid arthritis
-
Rong C, Hu W, Wu FR, Cao XJ, Chen FH. Interleukin-23 as a potential therapeutic target for rheumatoid arthritis. Mol Cell Biochem 2012; 361:243-248.
-
(2012)
Mol Cell Biochem
, vol.361
, pp. 243-248
-
-
Rong, C.1
Hu, W.2
Wu, F.R.3
Cao, X.J.4
Chen, F.H.5
-
30
-
-
34547734621
-
Phenotypic and functional features of human Th17 cells
-
Annunziato F, Cosmi L, Santarlasci V etal. Phenotypic and functional features of human Th17 cells. J Exp Med 2007; 204:1849-1861.
-
(2007)
J Exp Med
, vol.204
, pp. 1849-1861
-
-
Annunziato, F.1
Cosmi, L.2
Santarlasci, V.3
-
31
-
-
34547214205
-
Regulatory T-cell immunotherapy for tolerance to self antigens and alloantigens in humans
-
Roncarolo MG, Battaglia M. Regulatory T-cell immunotherapy for tolerance to self antigens and alloantigens in humans. Nat Rev Immunol 2007; 7:585-598.
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 585-598
-
-
Roncarolo, M.G.1
Battaglia, M.2
-
32
-
-
0025733855
-
The role of IL-10 in crossregulation of TH1 and TH2 responses
-
Mosmann TR, Moore KW. The role of IL-10 in crossregulation of TH1 and TH2 responses. Immunol Today 1991; 12:A49-53.
-
(1991)
Immunol Today
, vol.12
-
-
Mosmann, T.R.1
Moore, K.W.2
-
33
-
-
72849131815
-
Th22 cells represent a distinct human T cell subset involved in epidermal immunity and remodeling
-
Eyerich S, Eyerich K, Pennino D etal. Th22 cells represent a distinct human T cell subset involved in epidermal immunity and remodeling. J Clin Invest 2009; 119:3573-3585.
-
(2009)
J Clin Invest
, vol.119
, pp. 3573-3585
-
-
Eyerich, S.1
Eyerich, K.2
Pennino, D.3
-
34
-
-
79956077563
-
T cell exhaustion
-
Wherry EJ. T cell exhaustion. Nat Immunol 2011; 12:492-499.
-
(2011)
Nat Immunol
, vol.12
, pp. 492-499
-
-
Wherry, E.J.1
-
35
-
-
65449141433
-
Loss of FOXP3 expression in natural human CD4+CD25+ regulatory T cells upon repetitive in vitro stimulation
-
Hoffmann P, Boeld TJ, Eder R etal. Loss of FOXP3 expression in natural human CD4+CD25+ regulatory T cells upon repetitive in vitro stimulation. Eur J Immunol 2009; 39:1088-1097.
-
(2009)
Eur J Immunol
, vol.39
, pp. 1088-1097
-
-
Hoffmann, P.1
Boeld, T.J.2
Eder, R.3
-
36
-
-
72949104568
-
Translational mini-review series on Th17 cells: CD4 T helper cells: functional plasticity and differential sensitivity to regulatory T cell-mediated regulation
-
O'Connor RA, Taams LS, Anderton SM. Translational mini-review series on Th17 cells: CD4 T helper cells: functional plasticity and differential sensitivity to regulatory T cell-mediated regulation. Clin Exp Immunol 2010; 159:137-147.
-
(2010)
Clin Exp Immunol
, vol.159
, pp. 137-147
-
-
O'Connor, R.A.1
Taams, L.S.2
Anderton, S.M.3
-
37
-
-
33646505764
-
Altered keratin 17 peptide ligands inhibit in vitro proliferation of keratinocytes and T cells isolated from patients with psoriasis
-
Shen Z, Chen L, Liu YF etal. Altered keratin 17 peptide ligands inhibit in vitro proliferation of keratinocytes and T cells isolated from patients with psoriasis. J Am Acad Dermatol 2006; 54:992-1002.
-
(2006)
J Am Acad Dermatol
, vol.54
, pp. 992-1002
-
-
Shen, Z.1
Chen, L.2
Liu, Y.F.3
-
38
-
-
0032825299
-
Selection of conserved TCR VDJ rearrangements in chronic psoriatic plaques indicates a common antigen in psoriasis vulgaris
-
Prinz JC, Vollmer S, Boehncke WH, Menssen A, Laisney I, Trommler P. Selection of conserved TCR VDJ rearrangements in chronic psoriatic plaques indicates a common antigen in psoriasis vulgaris. Eur J Immunol 1999; 29:3360-3368.
-
(1999)
Eur J Immunol
, vol.29
, pp. 3360-3368
-
-
Prinz, J.C.1
Vollmer, S.2
Boehncke, W.H.3
Menssen, A.4
Laisney, I.5
Trommler, P.6
-
39
-
-
80052143748
-
Multiparameter grouping delineates heterogeneous populations of human IL-17 and/or IL-22 T-cell producers that share antigen specificities with other T-cell subsets
-
Larsen M, Arnaud L, Hie M etal. Multiparameter grouping delineates heterogeneous populations of human IL-17 and/or IL-22 T-cell producers that share antigen specificities with other T-cell subsets. Eur J Immunol 2011; 41:2596-2605.
-
(2011)
Eur J Immunol
, vol.41
, pp. 2596-2605
-
-
Larsen, M.1
Arnaud, L.2
Hie, M.3
-
40
-
-
0142151733
-
The fine specificity and cytokine profile of T-helper cells responsive to the alpha3 chain of type IV collagen in Goodpasture's disease
-
Cairns LS, Phelps RG, Bowie L etal. The fine specificity and cytokine profile of T-helper cells responsive to the alpha3 chain of type IV collagen in Goodpasture's disease. J Am Soc Nephrol 2003; 14:2801-2812.
-
(2003)
J Am Soc Nephrol
, vol.14
, pp. 2801-2812
-
-
Cairns, L.S.1
Phelps, R.G.2
Bowie, L.3
-
41
-
-
0037114635
-
Interleukin-10-mediated regulatory T-cell responses to epitopes on a human red blood cell autoantigen
-
Hall AM, Ward FJ, Vickers MA, Stott LM, Urbaniak SJ, Barker RN. Interleukin-10-mediated regulatory T-cell responses to epitopes on a human red blood cell autoantigen. Blood 2002; 100:4529-4536.
-
(2002)
Blood
, vol.100
, pp. 4529-4536
-
-
Hall, A.M.1
Ward, F.J.2
Vickers, M.A.3
Stott, L.M.4
Urbaniak, S.J.5
Barker, R.N.6
-
42
-
-
34248336272
-
Mapping helper T-cell epitopes on platelet membrane glycoprotein IIIa in chronic autoimmune thrombocytopenic purpura
-
Sukati H, Watson HG, Urbaniak SJ, Barker RN. Mapping helper T-cell epitopes on platelet membrane glycoprotein IIIa in chronic autoimmune thrombocytopenic purpura. Blood 2007; 109:4528-4538.
-
(2007)
Blood
, vol.109
, pp. 4528-4538
-
-
Sukati, H.1
Watson, H.G.2
Urbaniak, S.J.3
Barker, R.N.4
-
43
-
-
36248965294
-
TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T(H)-17 cell-mediated pathology
-
McGeachy MJ, Bak-Jensen KS, Chen Y etal. TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T(H)-17 cell-mediated pathology. Nat Immunol 2007; 8:1390-1397.
-
(2007)
Nat Immunol
, vol.8
, pp. 1390-1397
-
-
McGeachy, M.J.1
Bak-Jensen, K.S.2
Chen, Y.3
|