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Volumn 4, Issue 6, 2013, Pages 1018-1024

Design and synthesis of β-amino alcohol based β-lactam-isatin chimeras and preliminary analysis of in vitro activity against the protozoal pathogen Trichomonas vaginalis

(8) Nisha, a Mehra, Vishu a Hopper, Melissa b Patel, Neal b Hall, Dominique b Wrischnik, Lisa A b Land, Kirkwood M b Kumar, Vipan a

a GURU NANAK DEV UNIVERSITY (India)

b UNIVERSITY OF THE PACIFIC (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 [2 (1 CYCLOHEXYL 2 OXO 4 STYRYLAZETIDIN 3 YLAMINO) 3 HYDROXYPROPYL] 1H INDOLE 2,3 DIONE; 1 [2 (1 CYCLOHEXYL 2 OXO 4 STYRYLAZETIDIN 3 YLAMINO) 3 HYDROXYPROPYL] 5 METHYL 1H INDOLE 2,3 DIONE; 1 [2 [1 (4 CHLOROPHENYL) 2 OXO 4 STYRYLAZETIDIN 3 YLAMINO] 3 HYDROXYPROPYL] 1H INDOLE 2,3 DIONE; 1 [2 [1 (4 CHLOROPHENYL) 2 OXO 4 STYRYLAZETIDIN 3 YLAMINO] 3 HYDROXYPROPYL] 5 FLUORO 1H INDOLE 2,3 DIONE; 1 [2 [1 (4 CHLOROPHENYL) 2 OXO 4 STYRYLAZETIDIN 3 YLAMINO] 3 HYDROXYPROPYL] 5 METHYL 1H INDOLE 2,3 DIONE; 1 [3 HYDROXY 2 (2 OXO 4 STYRYL 1,4 TOLYLAZETIDIN 3 YLAMINO)PROPYL] 1H INDOLE 2,3 DIONE; 1 [3 HYDROXY 2 (2 OXO 4 STYRYL 1,4 TOLYLAZETIDIN 3 YLAMINO)PROPYL] 5 METHYL 1H INDOLE 2,3 DIONE; 5 CHLORO 1 [2 (1 CYCLOHEXYL 2 OXO 4 STYRYLAZETIDIN 3 YLAMINO) 3 HYDROXYPROPYL] 1H INDOLE 2,3 DIONE; 5 CHLORO 1 [2 [1 (4 CHLOROPHENYL) 2 OXO 4 STYRYLAZETIDIN 3 YLAMINO] 3 HYDROXYPROPYL] 1H INDOLE 2,3 DIONE; 5 FLUORO 1 [3 HYDROXY 2 (2 OXO 4 STYRYL 1,4 TOLYLAZETIDIN 3 YLAMINO)PROPYL] 1H INDOLE 2,3 DIONE; ANTIPROTOZOAL AGENT; BETA ALCOHOL DERIVATIVE; BETA LACTAM ISATIN DERIVATIVE; METRONIDAZOLE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIPROTOZOAL ACTIVITY; ARTICLE; BLOOD BRAIN BARRIER; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG DESIGN; DRUG PENETRATION; DRUG PROTEIN BINDING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HYDROGEN BOND; IN VITRO STUDY; INTESTINE ABSORPTION; NONHUMAN; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; TRICHOMONAS VAGINALIS;

TRICHOMONAS VAGINALIS;

EID: 84878784314 PISSN: 20402503 EISSN: 20402511 Source Type: Journal
DOI: 10.1039/c3md00057e Document Type: Article

Times cited : (21)

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