Antileishmanial activity of HIV protease inhibitors

International Journal of Antimicrobial Agents

Volumn 26, Issue 1, 2005, Pages 92-94

  Savoia, Dianella ^a   Allice, Tiziano ^a   Tovo, Pier Angelo ^b  

^a UNIVERSITY OF TURIN   (Italy)

^b UNIVERSITY OF TURIN   (Italy)

Author keywords

Leishmania infantum; Leishmania major; Protease inhibitors; Proteasomes

Indexed keywords

BS 00120083; INDINAVIR; PROTEINASE INHIBITOR; SAQUINAVIR;

AMASTIGOTE; ANTIPROTOZOAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG EFFICACY; LD 50; LEISHMANIA INFANTUM; LEISHMANIA MAJOR; LEISHMANIASIS; MACROPHAGE; MICROBIAL GROWTH; NONHUMAN; OBSERVATION; PRIORITY JOURNAL; SEROLOGY; VALIDATION PROCESS;

ANIMALS; ANTIPROTOZOAL AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; HIV PROTEASE INHIBITORS; INDINAVIR; LEISHMANIA INFANTUM; LEISHMANIA MAJOR; LETHAL DOSE 50; SAQUINAVIR;

EID: 20744432777     PISSN: 09248579     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijantimicag.2005.04.003     Document Type: Article

References (22)

1. H.W. Murray Kala-azar as an AIDS-related opportunistic infection AIDS Patient Care STDS 13 1999 459 465
2. C.P. Thakur, S. Narayan, and A. Ranjan Kala-azar (visceral leishmaniasis) and HIV coinfection in Bihar, India: is this combination increasing? J Acquir Immune Defic Syndr 32 2003 572 573
3. M.A. Morales, I. Cruz, and J.M. Rubio Relapses versus reinfections in patients coinfected with Leishmania infantum and human immunodeficiency virus type 1 J Infect Dis 185 2002 1533 1537
4. P. Del Giudice, M. Mary-Krause, and C. Pradier Impact of highly active antiretroviral therapy on the incidence of visceral leishmaniasis in a French cohort of patients infected with human immunodeficiency virus J Infect Dis 186 2002 1366 1370
5. R. De La Rosa, JA. Pineda, and J. Delgado Incidence and risk factors for symptomatic visceral leishmaniasis among human immunodeficiency virus type 1-infected patients from Spain in the era of highly active antiretroviral therapy J Clin Microbiol 40 2002 762 767
6. M. Piccinini, M.T. Rinaudo, and N. Chiapello The human 26S proteasome is a target of antiretroviral agents AIDS 16 2002 693 700
7. M. Piccinini, M.T. Rinaudo, and A. Anselmino The HIV protease inhibitors nelfinavir and saquinavir, but not a variety of HIV reverse transcriptase inhibitors, adversely affect human proteasome function Antivir Ther 10 2005 215 223
8. Z. Li, C.B. Zou, and Y. Yao An easily dissociated 26S proteasome catalyzes an essential ubiquitin-mediated protein degradation pathway in Trypanosoma brucei J Biol Chem 277 2002 15486 15498
9. J.L. De Diego, J.M. Katz, and P. Marshall The ubiquitin-proteasome pathway plays an essential role in proteolysis during Trypanosoma cruzi remodeling Biochemistry 40 2001 1053 1062
10. M.K. Shaw, C.Y. He, D.S. Roos, and L.G. Tilney Proteasome inhibitors block intracellular growth and replication of Toxoplasma gondii Parasitology 121 2000 35 47
11. S.M. Gantt, J.M. Myung, and M.R. Briones Proteasome inhibitors block development of Plasmodium spp Antimicrob Agents Chemother 42 1998 2731 2738
12. A. Makioka, M. Kumagai, H. Ohtomo, S. Kobayashi, and T. Takeuchi Effect of proteasome inhibitors on the growth, encystation, and excystation of Entamoeba histolytica and Entamoeba invadens Parasitol Res 88 2002 454 459
13. C.D. Robertson The Leishmania mexicana proteasome Mol Biochem Parasitol 103 1999 49 60
14. C.B. Christensen, L. Jorgensen, and A.T. Jensen Molecular characterization of a Leishmania donovani cDNA clone with similarity to human 20S proteasome α-type subunit Biochim Biophys Acta 1500 2000 77 87
15. G.D. Li, J.L. Li, M. Mugthin, and S.A. Ward Molecular cloning of a gene encoding a 20S proteasome beta subunit from Plasmodium falciparum Int J Parasitol 30 2000 729 733
16. M. Calonge, J.C. Cubria, R. Balana-Fouce, and D. Ordonez Putrescine active uptake system in the trypanosomatid Crithidia fasciculata Biol Chem Hoppe Seyler 377 1996 233 238
17. D. Savoia, C. Avanzini, T. Allice, E. Callone, G. Guella, and F. Dini Antimicrobial activity of euplotin C, the sesquiterpene taxonomic marker from the marine ciliate Euplotes crassus Antimicrob Agents Chemother 48 2004 3828 3833
18. R. Mukhopadhyay, and R. Madhubala Effects of bis(benzyl)polyamine analogs on Leishmania donovani promastigotes Exp Parasitol 81 1995 39 46
19. F. De Bernardis, E. Tacconelli, and F. Mondello Anti-retroviral therapy with protease inhibitors decreases virulence enzyme expression in vivo by Candida albicans without selection of avirulent fungus strains or decreasing their anti-mycotic susceptibility FEMS Immunol Med Microbiol 41 2004 27 34
20. E. Blasi, B. Colombari, and C.F. Orsi The human immunodeficiency virus (HIV) protease inhibitor indinavir affects the opportunistic fungal pathogen Cryptococcus neoformans FEMS Immunol Med Microbiol 42 2004 187 195
21. C. Atzori, M. Clerici, and D. Trabattoni Assessment of immune reconstitution to Pneumocystis carinii in HIV-1 patients under different highly active antiretroviral therapy regimens J Antimicrob Chemother 52 2003 276 281
22. V. Hommer, J. Eichholz, and F. Petry Effect of antiretroviral protease inhibitors alone, and in combination with paromomycin, on the excystation, invasion and in vitro development of Cryptosporidium parvum J Antimicrob Chemother 52 2003 359 364