IgG1 thioether bond formation in vivo

Journal of Biological Chemistry

Volumn 288, Issue 23, 2013, Pages 16371-16382

  Zhang, Qingchun ^a   Schenauer, Matthew R ^a   McCarter, John D ^a   Flynn, Gregory C ^a  

^a AMGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONVERSION RATES; HEALTHY HUMANS; LIGHT CHAIN; MECHANISTIC STUDIES; RECOMBINANT ANTIBODY; THERAPEUTIC ANTIBODIES; THIOETHER BONDS; THIOETHERS;

REACTION RATES;

ANTIBODIES;

IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G1 ANTIBODY; IMMUNOGLOBULIN KAPPA CHAIN; IMMUNOGLOBULIN LAMBDA CHAIN; POLYPEPTIDE; RECOMBINANT ANTIBODY; SULFIDE;

ARTICLE; CATALYSIS; CHEMICAL BOND; CHEMICAL STRUCTURE; CONTROLLED STUDY; DEHYDROGENATION; HUMAN; IN VITRO STUDY; IN VIVO STUDY; LIGHT CHAIN; PEPTIDE ANALYSIS; PH MEASUREMENT; PRIORITY JOURNAL; PRODUCT SAFETY; REACTION ANALYSIS; TEMPERATURE SENSITIVITY;

ANTIBODIES; DISULFIDE; DRUG DEVELOPMENT; LIGHT CHAIN; MASS SPECTROMETRY (MS); POST TRANSLATIONAL MODIFICATION;

ANIMALS; CHO CELLS; CRICETINAE; CRICETULUS; HUMANS; IMMUNOGLOBULIN G; IMMUNOGLOBULIN KAPPA-CHAINS; IMMUNOGLOBULIN LAMBDA-CHAINS; RECOMBINANT PROTEINS; SULFIDES;

EID: 84878752552     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.468397     Document Type: Article

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