메뉴 건너뛰기




Volumn 62, Issue , 2013, Pages 43-50

Induced pluripotent stem cells as a new strategy for cardiac regeneration and disease modeling

Author keywords

Cardiac differentiation; Cardiac regeneration; Cell reprogramming; Induced pluripotent stem (iPS) cells; Stem cell therapy

Indexed keywords

4 [4 (1,3 BENZODIOXOL 5 YL) 5 (2 PYRIDINYL) 1H IMIDAZOL 2 YL]BENZAMIDE; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CHIR 99021; CYCLOSPORIN A; CYTOKINE; DANTROLENE; DORSOMORPHIN; GAMMA SECRETASE INHIBITOR; GRANULOCYTE COLONY STIMULATING FACTOR; IWR 1; IWR 2; IWR 4; NIFEDIPINE; PINACIDIL; PROTEIN INHIBITOR; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

EID: 84878730741     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2013.04.022     Document Type: Review
Times cited : (55)

References (86)
  • 1
    • 84872091789 scopus 로고    scopus 로고
    • Heart Disease and Stroke Statistics-2013 update: a report from the American Heart Association
    • Go A.S., Mozaffarian D., Roger V.L., Benjamin E.J., Berry J.D., Borden W.B., et al. Heart Disease and Stroke Statistics-2013 update: a report from the American Heart Association. Circulation 2013, 127:6-245.
    • (2013) Circulation , vol.127 , pp. 6-245
    • Go, A.S.1    Mozaffarian, D.2    Roger, V.L.3    Benjamin, E.J.4    Berry, J.D.5    Borden, W.B.6
  • 2
    • 43749100265 scopus 로고    scopus 로고
    • Stem-cell-based therapy and lessons from the heart
    • Passier R., van Laake L.W., Mummery C.L. Stem-cell-based therapy and lessons from the heart. Nature 2008, 453:322-329.
    • (2008) Nature , vol.453 , pp. 322-329
    • Passier, R.1    van Laake, L.W.2    Mummery, C.L.3
  • 3
    • 10744228523 scopus 로고    scopus 로고
    • Adult cardiac stem cells are multipotent and support myocardial regeneration
    • Beltrami A.P., Barlucchi L., Torella D., Baker M., Limana F., Chimenti S., et al. Adult cardiac stem cells are multipotent and support myocardial regeneration. Cell 2003, 114:763-776.
    • (2003) Cell , vol.114 , pp. 763-776
    • Beltrami, A.P.1    Barlucchi, L.2    Torella, D.3    Baker, M.4    Limana, F.5    Chimenti, S.6
  • 4
    • 34547699399 scopus 로고    scopus 로고
    • Evidence from a genetic fate-mapping study that stem cells refresh adult mammalian cardiomyocytes after injury
    • Hsieh P.C., Segers V.F., Davis M.E., MacGillivray C., Gannon J., Molkentin J.D., et al. Evidence from a genetic fate-mapping study that stem cells refresh adult mammalian cardiomyocytes after injury. Nat Med 2007, 13:970-974.
    • (2007) Nat Med , vol.13 , pp. 970-974
    • Hsieh, P.C.1    Segers, V.F.2    Davis, M.E.3    MacGillivray, C.4    Gannon, J.5    Molkentin, J.D.6
  • 5
    • 77953665601 scopus 로고    scopus 로고
    • A new direction for cardiac regeneration therapy: application of synergistically acting epicardium-derived cells and cardiomyocyte progenitor cells
    • Winter E.M., van Oorschot A.A., Hogers B., van der Graaf L.M., Doevendans P.A., Poelmann R.E., et al. A new direction for cardiac regeneration therapy: application of synergistically acting epicardium-derived cells and cardiomyocyte progenitor cells. Circ Heart Fail 2009, 2:643-653.
    • (2009) Circ Heart Fail , vol.2 , pp. 643-653
    • Winter, E.M.1    van Oorschot, A.A.2    Hogers, B.3    van der Graaf, L.M.4    Doevendans, P.A.5    Poelmann, R.E.6
  • 6
    • 74949120679 scopus 로고    scopus 로고
    • Intracoronary administration of cardiac progenitor cells alleviates left ventricular dysfunction in rats with a 30-day-old infarction
    • Tang X.L., Rokosh G., Sanganalmath S.K., Yuan F., Sato H., Mu J., et al. Intracoronary administration of cardiac progenitor cells alleviates left ventricular dysfunction in rats with a 30-day-old infarction. Circulation 2010, 121:293-305.
    • (2010) Circulation , vol.121 , pp. 293-305
    • Tang, X.L.1    Rokosh, G.2    Sanganalmath, S.K.3    Yuan, F.4    Sato, H.5    Mu, J.6
  • 7
    • 82255175382 scopus 로고    scopus 로고
    • Cardiac stem cells in patients with ischaemic cardiomyopathy (SCIPIO): initial results of a randomised phase 1 trial
    • Bolli R., Chugh A.R., D'Amario D., Loughran J.H., Stoddard M.F., Ikram S., et al. Cardiac stem cells in patients with ischaemic cardiomyopathy (SCIPIO): initial results of a randomised phase 1 trial. Lancet 2011, 378:1847-1857.
    • (2011) Lancet , vol.378 , pp. 1847-1857
    • Bolli, R.1    Chugh, A.R.2    D'Amario, D.3    Loughran, J.H.4    Stoddard, M.F.5    Ikram, S.6
  • 9
    • 34948891467 scopus 로고    scopus 로고
    • Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts
    • Laflamme M.A., Chen K.Y., Naumova A.V., Muskheli V., Fugate J.A., Dupras S.K., et al. Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts. Nat Biotechnol 2007, 25:1015-1024.
    • (2007) Nat Biotechnol , vol.25 , pp. 1015-1024
    • Laflamme, M.A.1    Chen, K.Y.2    Naumova, A.V.3    Muskheli, V.4    Fugate, J.A.5    Dupras, S.K.6
  • 10
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • Takahashi K., Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006, 126:663-676.
    • (2006) Cell , vol.126 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 11
    • 36248966518 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from adult human fibroblasts by defined factors
    • Takahashi K., Tanabe K., Ohnuki M., Narita M., Ichisaka T., Tomoda K., et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007, 131:861-872.
    • (2007) Cell , vol.131 , pp. 861-872
    • Takahashi, K.1    Tanabe, K.2    Ohnuki, M.3    Narita, M.4    Ichisaka, T.5    Tomoda, K.6
  • 13
    • 77958569435 scopus 로고    scopus 로고
    • Induced pluripotency: history, mechanisms, and applications
    • Stadtfeld M., Hochedlinger K. Induced pluripotency: history, mechanisms, and applications. Genes Dev 2010, 24:2239-2263.
    • (2010) Genes Dev , vol.24 , pp. 2239-2263
    • Stadtfeld, M.1    Hochedlinger, K.2
  • 14
    • 84856007232 scopus 로고    scopus 로고
    • The promise of induced pluripotent stem cells in research and therapy
    • Robinton D.A., Daley G.Q. The promise of induced pluripotent stem cells in research and therapy. Nature 2012, 481:295-305.
    • (2012) Nature , vol.481 , pp. 295-305
    • Robinton, D.A.1    Daley, G.Q.2
  • 15
    • 62949220231 scopus 로고    scopus 로고
    • Molecules that promote or enhance reprogramming of somatic cells to induced pluripotent stem cells
    • Feng B., Ng J.H., Heng J.C., Ng H.H. Molecules that promote or enhance reprogramming of somatic cells to induced pluripotent stem cells. Cell Stem Cell 2009, 4:301-312.
    • (2009) Cell Stem Cell , vol.4 , pp. 301-312
    • Feng, B.1    Ng, J.H.2    Heng, J.C.3    Ng, H.H.4
  • 16
    • 34249880066 scopus 로고    scopus 로고
    • Generation of germline-competent induced pluripotent stem cells
    • Okita K., Ichisaka T., Yamanaka S. Generation of germline-competent induced pluripotent stem cells. Nature 2007, 448:313-317.
    • (2007) Nature , vol.448 , pp. 313-317
    • Okita, K.1    Ichisaka, T.2    Yamanaka, S.3
  • 17
    • 0032127977 scopus 로고    scopus 로고
    • Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3
    • Niwa H., Burdon T., Chambers I., Smith A. Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3. Genes Dev 1998, 12:2048-2060.
    • (1998) Genes Dev , vol.12 , pp. 2048-2060
    • Niwa, H.1    Burdon, T.2    Chambers, I.3    Smith, A.4
  • 18
    • 0024205842 scopus 로고
    • Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells
    • Williams R.L., Hilton D.J., Pease S., Willson T.A., Stewart C.L., Gearing D.P., et al. Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells. Nature 1988, 336:684-687.
    • (1988) Nature , vol.336 , pp. 684-687
    • Williams, R.L.1    Hilton, D.J.2    Pease, S.3    Willson, T.A.4    Stewart, C.L.5    Gearing, D.P.6
  • 19
    • 0344845415 scopus 로고    scopus 로고
    • BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3
    • Ying Q.L., Nichols J., Chambers I., Smith A. BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3. Cell 2003, 115:281-292.
    • (2003) Cell , vol.115 , pp. 281-292
    • Ying, Q.L.1    Nichols, J.2    Chambers, I.3    Smith, A.4
  • 20
    • 0035189927 scopus 로고    scopus 로고
    • Embryo-derived stem cells: of mice and men
    • Smith A.G. Embryo-derived stem cells: of mice and men. Annu Rev Cell Dev Biol 2001, 17:435-462.
    • (2001) Annu Rev Cell Dev Biol , vol.17 , pp. 435-462
    • Smith, A.G.1
  • 21
    • 33747614295 scopus 로고    scopus 로고
    • Activin A maintains self-renewal and regulates fibroblast growth factor, Wnt, and bone morphogenic protein pathways in human embryonic stem cells
    • Xiao L., Yuan X., Sharkis S.J. Activin A maintains self-renewal and regulates fibroblast growth factor, Wnt, and bone morphogenic protein pathways in human embryonic stem cells. Stem Cells 2006, 24:1476-1486.
    • (2006) Stem Cells , vol.24 , pp. 1476-1486
    • Xiao, L.1    Yuan, X.2    Sharkis, S.J.3
  • 22
    • 67649222358 scopus 로고    scopus 로고
    • Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures
    • Chin M.H., Mason M.J., Xie W., Volinia S., Singer M., Peterson C., et al. Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures. Cell Stem Cell 2009, 5:111-123.
    • (2009) Cell Stem Cell , vol.5 , pp. 111-123
    • Chin, M.H.1    Mason, M.J.2    Xie, W.3    Volinia, S.4    Singer, M.5    Peterson, C.6
  • 25
    • 77957325592 scopus 로고    scopus 로고
    • Persistent donor cell gene expression among human induced pluripotent stem cells contributes to differences with human embryonic stem cells
    • Ghosh Z., Wilson K.D., Wu Y., Hu S., Quertermous T., Wu J.C. Persistent donor cell gene expression among human induced pluripotent stem cells contributes to differences with human embryonic stem cells. PLoS One 2010, 5:e8975.
    • (2010) PLoS One , vol.5
    • Ghosh, Z.1    Wilson, K.D.2    Wu, Y.3    Hu, S.4    Quertermous, T.5    Wu, J.C.6
  • 26
    • 79957807595 scopus 로고    scopus 로고
    • Immunogenicity of induced pluripotent stem cells
    • Zhao T., Zhang Z.N., Rong Z., Xu Y. Immunogenicity of induced pluripotent stem cells. Nature 2011, 474:212-215.
    • (2011) Nature , vol.474 , pp. 212-215
    • Zhao, T.1    Zhang, Z.N.2    Rong, Z.3    Xu, Y.4
  • 27
    • 84874682918 scopus 로고    scopus 로고
    • Negligible immunogenicity of terminally differentiated cells derived from induced pluripotent or embryonic stem cells
    • Araki R., Uda M., Hoki Y., Sunayama M., Nakamura M., Ando S., et al. Negligible immunogenicity of terminally differentiated cells derived from induced pluripotent or embryonic stem cells. Nature 2013, 494:100-104.
    • (2013) Nature , vol.494 , pp. 100-104
    • Araki, R.1    Uda, M.2    Hoki, Y.3    Sunayama, M.4    Nakamura, M.5    Ando, S.6
  • 28
    • 78649443533 scopus 로고    scopus 로고
    • Induced pluripotent stem cells: developmental biology to regenerative medicine
    • Nelson T.J., Martinez-Fernandez A., Terzic A. Induced pluripotent stem cells: developmental biology to regenerative medicine. Nat Rev Cardiol 2010, 7:700-710.
    • (2010) Nat Rev Cardiol , vol.7 , pp. 700-710
    • Nelson, T.J.1    Martinez-Fernandez, A.2    Terzic, A.3
  • 29
    • 77956163474 scopus 로고    scopus 로고
    • Generation of rat pancreas in mouse by interspecific blastocyst injection of pluripotent stem cells
    • Kobayashi T., Yamaguchi T., Hamanaka S., Kato-Itoh M., Yamazaki Y., Ibata M., et al. Generation of rat pancreas in mouse by interspecific blastocyst injection of pluripotent stem cells. Cell 2010, 142:787-799.
    • (2010) Cell , vol.142 , pp. 787-799
    • Kobayashi, T.1    Yamaguchi, T.2    Hamanaka, S.3    Kato-Itoh, M.4    Yamazaki, Y.5    Ibata, M.6
  • 31
    • 78650752402 scopus 로고    scopus 로고
    • Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells
    • Polo J.M., Liu S., Figueroa M.E., Kulalert W., Eminli S., Tan K.Y., et al. Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells. Nat Biotechnol 2010, 28:848-855.
    • (2010) Nat Biotechnol , vol.28 , pp. 848-855
    • Polo, J.M.1    Liu, S.2    Figueroa, M.E.3    Kulalert, W.4    Eminli, S.5    Tan, K.Y.6
  • 32
    • 79959992876 scopus 로고    scopus 로고
    • Epigenetic memory and preferential lineage-specific differentiation in induced pluripotent stem cells derived from human pancreatic islet beta cells
    • Bar-Nur O., Russ H.A., Efrat S., Benvenisty N. Epigenetic memory and preferential lineage-specific differentiation in induced pluripotent stem cells derived from human pancreatic islet beta cells. Cell Stem Cell 2011, 9:17-23.
    • (2011) Cell Stem Cell , vol.9 , pp. 17-23
    • Bar-Nur, O.1    Russ, H.A.2    Efrat, S.3    Benvenisty, N.4
  • 33
    • 49649096192 scopus 로고    scopus 로고
    • Generation of functional murine cardiac myocytes from induced pluripotent stem cells
    • Mauritz C., Schwanke K., Reppel M., Neef S., Katsirntaki K., Maier L.S., et al. Generation of functional murine cardiac myocytes from induced pluripotent stem cells. Circulation 2008, 118:507-517.
    • (2008) Circulation , vol.118 , pp. 507-517
    • Mauritz, C.1    Schwanke, K.2    Reppel, M.3    Neef, S.4    Katsirntaki, K.5    Maier, L.S.6
  • 34
    • 84859418689 scopus 로고    scopus 로고
    • Efficient differentiation of human induced pluripotent stem cells generates cardiac cells that provide protection following myocardial infarction in the rat
    • Carpenter L., Carr C., Yang C.T., Stuckey D.J., Clarke K., Watt S.M. Efficient differentiation of human induced pluripotent stem cells generates cardiac cells that provide protection following myocardial infarction in the rat. Stem Cells Dev 2011, 21:977-986.
    • (2011) Stem Cells Dev , vol.21 , pp. 977-986
    • Carpenter, L.1    Carr, C.2    Yang, C.T.3    Stuckey, D.J.4    Clarke, K.5    Watt, S.M.6
  • 35
    • 49649120250 scopus 로고    scopus 로고
    • Directed and systematic differentiation of cardiovascular cells from mouse induced pluripotent stem cells
    • Narazaki G., Uosaki H., Teranishi M., Okita K., Kim B., Matsuoka S., et al. Directed and systematic differentiation of cardiovascular cells from mouse induced pluripotent stem cells. Circulation 2008, 118:498-506.
    • (2008) Circulation , vol.118 , pp. 498-506
    • Narazaki, G.1    Uosaki, H.2    Teranishi, M.3    Okita, K.4    Kim, B.5    Matsuoka, S.6
  • 36
    • 48649097575 scopus 로고    scopus 로고
    • Reprogrammed mouse fibroblasts differentiate into cells of the cardiovascular and hematopoietic lineages
    • Schenke-Layland K., Rhodes K.E., Angelis E., Butylkova Y., Heydarkhan-Hagvall S., Gekas C., et al. Reprogrammed mouse fibroblasts differentiate into cells of the cardiovascular and hematopoietic lineages. Stem Cells 2008, 26:1537-1546.
    • (2008) Stem Cells , vol.26 , pp. 1537-1546
    • Schenke-Layland, K.1    Rhodes, K.E.2    Angelis, E.3    Butylkova, Y.4    Heydarkhan-Hagvall, S.5    Gekas, C.6
  • 37
    • 67650318728 scopus 로고    scopus 로고
    • Induction and isolation of vascular cells from human induced pluripotent stem cells-brief report
    • Taura D., Sone M., Homma K., Oyamada N., Takahashi K., Tamura N., et al. Induction and isolation of vascular cells from human induced pluripotent stem cells-brief report. Arterioscler Thromb Vasc Biol 2009, 29:1100-1103.
    • (2009) Arterioscler Thromb Vasc Biol , vol.29 , pp. 1100-1103
    • Taura, D.1    Sone, M.2    Homma, K.3    Oyamada, N.4    Takahashi, K.5    Tamura, N.6
  • 38
    • 80053508177 scopus 로고    scopus 로고
    • Induced pluripotent stem cell (iPSC)-derived Flk-1 progenitor cells engraft, differentiate, and improve heart function in a mouse model of acute myocardial infarction
    • Mauritz C., Martens A., Rojas S.V., Schnick T., Rathert C., Schecker N., et al. Induced pluripotent stem cell (iPSC)-derived Flk-1 progenitor cells engraft, differentiate, and improve heart function in a mouse model of acute myocardial infarction. Eur Heart J 2011, 32:2634-2641.
    • (2011) Eur Heart J , vol.32 , pp. 2634-2641
    • Mauritz, C.1    Martens, A.2    Rojas, S.V.3    Schnick, T.4    Rathert, C.5    Schecker, N.6
  • 39
    • 77952306707 scopus 로고    scopus 로고
    • Mouse and human induced pluripotent stem cells as a source for multipotent Isl1+ cardiovascular progenitors
    • Moretti A., Bellin M., Jung C.B., Thies T.M., Takashima Y., Bernshausen A., et al. Mouse and human induced pluripotent stem cells as a source for multipotent Isl1+ cardiovascular progenitors. FASEB J 2009, 24:700-711.
    • (2009) FASEB J , vol.24 , pp. 700-711
    • Moretti, A.1    Bellin, M.2    Jung, C.B.3    Thies, T.M.4    Takashima, Y.5    Bernshausen, A.6
  • 40
    • 77955799446 scopus 로고    scopus 로고
    • Comparison of contractile behavior of native murine ventricular tissue and cardiomyocytes derived from embryonic or induced pluripotent stem cells
    • Xi J., Khalil M., Shishechian N., Hannes T., Pfannkuche K., Liang H., et al. Comparison of contractile behavior of native murine ventricular tissue and cardiomyocytes derived from embryonic or induced pluripotent stem cells. FASEB J 2010, 24:2739-2751.
    • (2010) FASEB J , vol.24 , pp. 2739-2751
    • Xi, J.1    Khalil, M.2    Shishechian, N.3    Hannes, T.4    Pfannkuche, K.5    Liang, H.6
  • 41
    • 0038210217 scopus 로고    scopus 로고
    • Differentiation of human embryonic stem cells to cardiomyocytes: role of coculture with visceral endoderm-like cells
    • Mummery C., Ward-van Oostwaard D., Doevendans P., Spijker R., van den Brink S., Hassink R., et al. Differentiation of human embryonic stem cells to cardiomyocytes: role of coculture with visceral endoderm-like cells. Circulation 2003, 107:2733-2740.
    • (2003) Circulation , vol.107 , pp. 2733-2740
    • Mummery, C.1    Ward-van Oostwaard, D.2    Doevendans, P.3    Spijker, R.4    van den Brink, S.5    Hassink, R.6
  • 42
    • 34147124971 scopus 로고    scopus 로고
    • Improved human embryonic stem cell embryoid body homogeneity and cardiomyocyte differentiation from a novel V-96 plate aggregation system highlights interline variability
    • Burridge P.W., Anderson D., Priddle H., Barbadillo Munoz M.D., Chamberlain S., Allegrucci C., et al. Improved human embryonic stem cell embryoid body homogeneity and cardiomyocyte differentiation from a novel V-96 plate aggregation system highlights interline variability. Stem Cells 2007, 25:929-938.
    • (2007) Stem Cells , vol.25 , pp. 929-938
    • Burridge, P.W.1    Anderson, D.2    Priddle, H.3    Barbadillo Munoz, M.D.4    Chamberlain, S.5    Allegrucci, C.6
  • 43
    • 79954543387 scopus 로고    scopus 로고
    • A universal system for highly efficient cardiac differentiation of human induced pluripotent stem cells that eliminates interline variability
    • Burridge P.W., Thompson S., Millrod M.A., Weinberg S., Yuan X., Peters A., et al. A universal system for highly efficient cardiac differentiation of human induced pluripotent stem cells that eliminates interline variability. PLoS One 2011, 6:e18293.
    • (2011) PLoS One , vol.6
    • Burridge, P.W.1    Thompson, S.2    Millrod, M.A.3    Weinberg, S.4    Yuan, X.5    Peters, A.6
  • 44
    • 82355175128 scopus 로고    scopus 로고
    • NKX2-5(eGFP/w) hESCs for isolation of human cardiac progenitors and cardiomyocytes
    • Elliott D.A., Braam S.R., Koutsis K., Ng E.S., Jenny R., Lagerqvist E.L., et al. NKX2-5(eGFP/w) hESCs for isolation of human cardiac progenitors and cardiomyocytes. Nat Methods 2011, 8:1037-1040.
    • (2011) Nat Methods , vol.8 , pp. 1037-1040
    • Elliott, D.A.1    Braam, S.R.2    Koutsis, K.3    Ng, E.S.4    Jenny, R.5    Lagerqvist, E.L.6
  • 45
    • 84867746044 scopus 로고    scopus 로고
    • Extracellular matrix promotes highly efficient cardiac differentiation of human pluripotent stem cells: the matrix sandwich method
    • Zhang J., Klos M., Wilson G.F., Herman A.M., Lian X., Raval K.K., et al. Extracellular matrix promotes highly efficient cardiac differentiation of human pluripotent stem cells: the matrix sandwich method. Circ Res 2012, 111:1125-1136.
    • (2012) Circ Res , vol.111 , pp. 1125-1136
    • Zhang, J.1    Klos, M.2    Wilson, G.F.3    Herman, A.M.4    Lian, X.5    Raval, K.K.6
  • 46
    • 77951181560 scopus 로고    scopus 로고
    • A purified population of multipotent cardiovascular progenitors derived from primate pluripotent stem cells engrafts in postmyocardial infarcted nonhuman primates
    • Blin G., Nury D., Stefanovic S., Neri T., Guillevic O., Brinon B., et al. A purified population of multipotent cardiovascular progenitors derived from primate pluripotent stem cells engrafts in postmyocardial infarcted nonhuman primates. J Clin Invest 2010, 120:1125-1139.
    • (2010) J Clin Invest , vol.120 , pp. 1125-1139
    • Blin, G.1    Nury, D.2    Stefanovic, S.3    Neri, T.4    Guillevic, O.5    Brinon, B.6
  • 47
    • 78650824203 scopus 로고    scopus 로고
    • Fibroblast growth factor-10 promotes cardiomyocyte differentiation from embryonic and induced pluripotent stem cells
    • Chan S.S., Li H.J., Hsueh Y.C., Lee D.S., Chen J.H., Hwang S.M., et al. Fibroblast growth factor-10 promotes cardiomyocyte differentiation from embryonic and induced pluripotent stem cells. PLoS One 2011, 5:e14414.
    • (2011) PLoS One , vol.5
    • Chan, S.S.1    Li, H.J.2    Hsueh, Y.C.3    Lee, D.S.4    Chen, J.H.5    Hwang, S.M.6
  • 48
    • 22844439586 scopus 로고    scopus 로고
    • Transient inhibition of BMP signaling by Noggin induces cardiomyocyte differentiation of mouse embryonic stem cells
    • Yuasa S., Itabashi Y., Koshimizu U., Tanaka T., Sugimura K., Kinoshita M., et al. Transient inhibition of BMP signaling by Noggin induces cardiomyocyte differentiation of mouse embryonic stem cells. Nat Biotechnol 2005, 23:607-611.
    • (2005) Nat Biotechnol , vol.23 , pp. 607-611
    • Yuasa, S.1    Itabashi, Y.2    Koshimizu, U.3    Tanaka, T.4    Sugimura, K.5    Kinoshita, M.6
  • 49
    • 84863560929 scopus 로고    scopus 로고
    • Robust cardiomyocyte differentiation from human pluripotent stem cells via temporal modulation of canonical Wnt signaling
    • Lian X., Hsiao C., Wilson G., Zhu K., Hazeltine L.B., Azarin S.M., et al. Robust cardiomyocyte differentiation from human pluripotent stem cells via temporal modulation of canonical Wnt signaling. Proc Natl Acad Sci U S A 2012, 109:E1848-E1857.
    • (2012) Proc Natl Acad Sci U S A , vol.109
    • Lian, X.1    Hsiao, C.2    Wilson, G.3    Zhu, K.4    Hazeltine, L.B.5    Azarin, S.M.6
  • 50
    • 80051796581 scopus 로고    scopus 로고
    • Small-molecule inhibitors of the Wnt pathway potently promote cardiomyocytes from human embryonic stem cell-derived mesoderm
    • Willems E., Spiering S., Davidovics H., Lanier M., Xia Z., Dawson M., et al. Small-molecule inhibitors of the Wnt pathway potently promote cardiomyocytes from human embryonic stem cell-derived mesoderm. Circ Res 2011, 109:360-364.
    • (2011) Circ Res , vol.109 , pp. 360-364
    • Willems, E.1    Spiering, S.2    Davidovics, H.3    Lanier, M.4    Xia, Z.5    Dawson, M.6
  • 51
    • 79960913156 scopus 로고    scopus 로고
    • Small molecule Wnt inhibitors enhance the efficiency of BMP-4-directed cardiac differentiation of human pluripotent stem cells
    • Ren Y., Lee M.Y., Schliffke S., Paavola J., Amos P.J., Ge X., et al. Small molecule Wnt inhibitors enhance the efficiency of BMP-4-directed cardiac differentiation of human pluripotent stem cells. J Mol Cell Cardiol 2011, 51:280-287.
    • (2011) J Mol Cell Cardiol , vol.51 , pp. 280-287
    • Ren, Y.1    Lee, M.Y.2    Schliffke, S.3    Paavola, J.4    Amos, P.J.5    Ge, X.6
  • 52
    • 33845928762 scopus 로고    scopus 로고
    • Developmental stage-specific biphasic roles of Wnt/beta-catenin signaling in cardiomyogenesis and hematopoiesis
    • Naito A.T., Shiojima I., Akazawa H., Hidaka K., Morisaki T., Kikuchi A., et al. Developmental stage-specific biphasic roles of Wnt/beta-catenin signaling in cardiomyogenesis and hematopoiesis. Proc Natl Acad Sci U S A 2006, 103:19812-19817.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 19812-19817
    • Naito, A.T.1    Shiojima, I.2    Akazawa, H.3    Hidaka, K.4    Morisaki, T.5    Kikuchi, A.6
  • 53
    • 34250802982 scopus 로고    scopus 로고
    • Biphasic role for Wnt/beta-catenin signaling in cardiac specification in zebrafish and embryonic stem cells
    • Ueno S., Weidinger G., Osugi T., Kohn A.D., Golob J.L., Pabon L., et al. Biphasic role for Wnt/beta-catenin signaling in cardiac specification in zebrafish and embryonic stem cells. Proc Natl Acad Sci U S A 2007, 104:9685-9690.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 9685-9690
    • Ueno, S.1    Weidinger, G.2    Osugi, T.3    Kohn, A.D.4    Golob, J.L.5    Pabon, L.6
  • 55
    • 79551597211 scopus 로고    scopus 로고
    • Stage-specific optimization of activin/nodal and BMP signaling promotes cardiac differentiation of mouse and human pluripotent stem cell lines
    • Kattman S.J., Witty A.D., Gagliardi M., Dubois N.C., Niapour M., Hotta A., et al. Stage-specific optimization of activin/nodal and BMP signaling promotes cardiac differentiation of mouse and human pluripotent stem cell lines. Cell Stem Cell 2011, 8:228-240.
    • (2011) Cell Stem Cell , vol.8 , pp. 228-240
    • Kattman, S.J.1    Witty, A.D.2    Gagliardi, M.3    Dubois, N.C.4    Niapour, M.5    Hotta, A.6
  • 56
    • 34447622302 scopus 로고    scopus 로고
    • Stage-specific role of endogenous Smad2 activation in cardiomyogenesis of embryonic stem cells
    • Kitamura R., Takahashi T., Nakajima N., Isodono K., Asada S., Ueno H., et al. Stage-specific role of endogenous Smad2 activation in cardiomyogenesis of embryonic stem cells. Circ Res 2007, 101:78-87.
    • (2007) Circ Res , vol.101 , pp. 78-87
    • Kitamura, R.1    Takahashi, T.2    Nakajima, N.3    Isodono, K.4    Asada, S.5    Ueno, H.6
  • 57
    • 84864610045 scopus 로고    scopus 로고
    • Small molecule-mediated TGF-beta type II receptor degradation promotes cardiomyogenesis in embryonic stem cells
    • Willems E., Cabral-Teixeira J., Schade D., Cai W., Reeves P., Bushway P.J., et al. Small molecule-mediated TGF-beta type II receptor degradation promotes cardiomyogenesis in embryonic stem cells. Cell Stem Cell 2012, 11:242-252.
    • (2012) Cell Stem Cell , vol.11 , pp. 242-252
    • Willems, E.1    Cabral-Teixeira, J.2    Schade, D.3    Cai, W.4    Reeves, P.5    Bushway, P.J.6
  • 58
    • 56249087950 scopus 로고    scopus 로고
    • Notch inhibition promotes human embryonic stem cell-derived cardiac mesoderm differentiation
    • Jang J., Ku S.Y., Kim J.E., Choi K., Kim Y.Y., Kim H.S., et al. Notch inhibition promotes human embryonic stem cell-derived cardiac mesoderm differentiation. Stem Cells 2008, 26:2782-2790.
    • (2008) Stem Cells , vol.26 , pp. 2782-2790
    • Jang, J.1    Ku, S.Y.2    Kim, J.E.3    Choi, K.4    Kim, Y.Y.5    Kim, H.S.6
  • 59
    • 84855487976 scopus 로고    scopus 로고
    • Ascorbic acid enhances the cardiac differentiation of induced pluripotent stem cells through promoting the proliferation of cardiac progenitor cells
    • Cao N., Liu Z., Chen Z., Wang J., Chen T., Zhao X., et al. Ascorbic acid enhances the cardiac differentiation of induced pluripotent stem cells through promoting the proliferation of cardiac progenitor cells. Cell Res 2011, 22:219-236.
    • (2011) Cell Res , vol.22 , pp. 219-236
    • Cao, N.1    Liu, Z.2    Chen, Z.3    Wang, J.4    Chen, T.5    Zhao, X.6
  • 60
    • 0037144701 scopus 로고    scopus 로고
    • Characterization and enrichment of cardiomyocytes derived from human embryonic stem cells
    • Xu C., Police S., Rao N., Carpenter M.K. Characterization and enrichment of cardiomyocytes derived from human embryonic stem cells. Circ Res 2002, 91:501-508.
    • (2002) Circ Res , vol.91 , pp. 501-508
    • Xu, C.1    Police, S.2    Rao, N.3    Carpenter, M.K.4
  • 61
    • 77449131670 scopus 로고    scopus 로고
    • G-CSF promotes the proliferation of developing cardiomyocytes in vivo and in derivation from ESCs and iPSCs
    • Shimoji K., Yuasa S., Onizuka T., Hattori F., Tanaka T., Hara M., et al. G-CSF promotes the proliferation of developing cardiomyocytes in vivo and in derivation from ESCs and iPSCs. Cell Stem Cell 2010, 6:227-237.
    • (2010) Cell Stem Cell , vol.6 , pp. 227-237
    • Shimoji, K.1    Yuasa, S.2    Onizuka, T.3    Hattori, F.4    Tanaka, T.5    Hara, M.6
  • 62
    • 79952050668 scopus 로고    scopus 로고
    • Induction enhancement of cardiac cell differentiation from mouse and human induced pluripotent stem cells with cyclosporin-A
    • Fujiwara M., Yan P., Otsuji T.G., Narazaki G., Uosaki H., Fukushima H., et al. Induction enhancement of cardiac cell differentiation from mouse and human induced pluripotent stem cells with cyclosporin-A. PLoS One 2011, 6:e16734.
    • (2011) PLoS One , vol.6
    • Fujiwara, M.1    Yan, P.2    Otsuji, T.G.3    Narazaki, G.4    Uosaki, H.5    Fukushima, H.6
  • 63
    • 79952273710 scopus 로고    scopus 로고
    • Conversion of mouse fibroblasts into cardiomyocytes using a direct reprogramming strategy
    • Efe J.A., Hilcove S., Kim J., Zhou H., Ouyang K., Wang G., et al. Conversion of mouse fibroblasts into cardiomyocytes using a direct reprogramming strategy. Nat Cell Biol 2011, 13:215-222.
    • (2011) Nat Cell Biol , vol.13 , pp. 215-222
    • Efe, J.A.1    Hilcove, S.2    Kim, J.3    Zhou, H.4    Ouyang, K.5    Wang, G.6
  • 64
    • 84865286051 scopus 로고    scopus 로고
    • Direct reprogramming of fibroblasts into endothelial cells capable of angiogenesis and reendothelialization in tissue-engineered vessels
    • Margariti A., Winkler B., Karamariti E., Zampetaki A., Tsai T.N., Baban D., et al. Direct reprogramming of fibroblasts into endothelial cells capable of angiogenesis and reendothelialization in tissue-engineered vessels. Proc Natl Acad Sci U S A 2012, 109:13793-13798.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 13793-13798
    • Margariti, A.1    Winkler, B.2    Karamariti, E.3    Zampetaki, A.4    Tsai, T.N.5    Baban, D.6
  • 65
    • 66649127942 scopus 로고    scopus 로고
    • Directed transdifferentiation of mouse mesoderm to heart tissue by defined factors
    • Takeuchi J.K., Bruneau B.G. Directed transdifferentiation of mouse mesoderm to heart tissue by defined factors. Nature 2009, 459:708-711.
    • (2009) Nature , vol.459 , pp. 708-711
    • Takeuchi, J.K.1    Bruneau, B.G.2
  • 66
    • 77955321344 scopus 로고    scopus 로고
    • Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors
    • Ieda M., Fu J.D., Delgado-Olguin P., Vedantham V., Hayashi Y., Bruneau B.G., et al. Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors. Cell 2010, 142:375-386.
    • (2010) Cell , vol.142 , pp. 375-386
    • Ieda, M.1    Fu, J.D.2    Delgado-Olguin, P.3    Vedantham, V.4    Hayashi, Y.5    Bruneau, B.G.6
  • 67
    • 84863629484 scopus 로고    scopus 로고
    • In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes
    • Qian L., Huang Y., Spencer C.I., Foley A., Vedantham V., Liu L., et al. In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes. Nature 2012, 485:593-598.
    • (2012) Nature , vol.485 , pp. 593-598
    • Qian, L.1    Huang, Y.2    Spencer, C.I.3    Foley, A.4    Vedantham, V.5    Liu, L.6
  • 68
    • 84867371272 scopus 로고    scopus 로고
    • Cardiac repair with thymosin beta4 and cardiac reprogramming factors
    • Srivastava D., Ieda M., Fu J., Qian L. Cardiac repair with thymosin beta4 and cardiac reprogramming factors. Ann N Y Acad Sci 2012, 1270:66-72.
    • (2012) Ann N Y Acad Sci , vol.1270 , pp. 66-72
    • Srivastava, D.1    Ieda, M.2    Fu, J.3    Qian, L.4
  • 69
    • 84863626782 scopus 로고    scopus 로고
    • Heart repair by reprogramming non-myocytes with cardiac transcription factors
    • Song K., Nam Y.J., Luo X., Qi X., Tan W., Huang G.N., et al. Heart repair by reprogramming non-myocytes with cardiac transcription factors. Nature 2012, 485:599-604.
    • (2012) Nature , vol.485 , pp. 599-604
    • Song, K.1    Nam, Y.J.2    Luo, X.3    Qi, X.4    Tan, W.5    Huang, G.N.6
  • 70
    • 85027957068 scopus 로고    scopus 로고
    • Inefficient reprogramming of fibroblasts into cardiomyocytes using Gata4, Mef2c, and Tbx5
    • Chen J.X., Krane M., Deutsch M.A., Wang L., Rav-Acha M., Gregoire S., et al. Inefficient reprogramming of fibroblasts into cardiomyocytes using Gata4, Mef2c, and Tbx5. Circ Res 2012, 111:50-55.
    • (2012) Circ Res , vol.111 , pp. 50-55
    • Chen, J.X.1    Krane, M.2    Deutsch, M.A.3    Wang, L.4    Rav-Acha, M.5    Gregoire, S.6
  • 71
    • 84861642380 scopus 로고    scopus 로고
    • MicroRNA-mediated in vitro and in vivo direct reprogramming of cardiac fibroblasts to cardiomyocytes
    • Jayawardena T.M., Egemnazarov B., Finch E.A., Zhang L., Payne J.A., Pandya K., et al. MicroRNA-mediated in vitro and in vivo direct reprogramming of cardiac fibroblasts to cardiomyocytes. Circ Res 2012, 110:1465-1473.
    • (2012) Circ Res , vol.110 , pp. 1465-1473
    • Jayawardena, T.M.1    Egemnazarov, B.2    Finch, E.A.3    Zhang, L.4    Payne, J.A.5    Pandya, K.6
  • 72
    • 82955222839 scopus 로고    scopus 로고
    • Biomaterials for the treatment of myocardial infarction: a 5-year update
    • Rane A.A., Christman K.L. Biomaterials for the treatment of myocardial infarction: a 5-year update. J Am Coll Cardiol 2011, 58:2615-2629.
    • (2011) J Am Coll Cardiol , vol.58 , pp. 2615-2629
    • Rane, A.A.1    Christman, K.L.2
  • 74
    • 79960023610 scopus 로고    scopus 로고
    • Growth of engineered human myocardium with mechanical loading and vascular coculture
    • Tulloch N.L., Muskheli V., Razumova M.V., Korte F.S., Regnier M., Hauch K.D., et al. Growth of engineered human myocardium with mechanical loading and vascular coculture. Circ Res 2011, 109:47-59.
    • (2011) Circ Res , vol.109 , pp. 47-59
    • Tulloch, N.L.1    Muskheli, V.2    Razumova, M.V.3    Korte, F.S.4    Regnier, M.5    Hauch, K.D.6
  • 75
    • 80155144279 scopus 로고    scopus 로고
    • Reduced collagen deposition in infarcted myocardium facilitates induced pluripotent stem cell engraftment and angiomyogenesis for improvement of left ventricular function
    • Dai B., Huang W., Xu M., Millard R.W., Gao M.H., Hammond H.K., et al. Reduced collagen deposition in infarcted myocardium facilitates induced pluripotent stem cell engraftment and angiomyogenesis for improvement of left ventricular function. J Am Coll Cardiol 2011, 58:2118-2127.
    • (2011) J Am Coll Cardiol , vol.58 , pp. 2118-2127
    • Dai, B.1    Huang, W.2    Xu, M.3    Millard, R.W.4    Gao, M.H.5    Hammond, H.K.6
  • 76
    • 84866466228 scopus 로고    scopus 로고
    • Feasibility, safety, and therapeutic efficacy of human induced pluripotent stem cell-derived cardiomyocyte sheets in a porcine ischemic cardiomyopathy model
    • Kawamura M., Miyagawa S., Miki K., Saito A., Fukushima S., Higuchi T., et al. Feasibility, safety, and therapeutic efficacy of human induced pluripotent stem cell-derived cardiomyocyte sheets in a porcine ischemic cardiomyopathy model. Circulation 2012, 126:S29-S37.
    • (2012) Circulation , vol.126
    • Kawamura, M.1    Miyagawa, S.2    Miki, K.3    Saito, A.4    Fukushima, S.5    Higuchi, T.6
  • 77
    • 84866150446 scopus 로고    scopus 로고
    • Human ES-cell-derived cardiomyocytes electrically couple and suppress arrhythmias in injured hearts
    • Shiba Y., Fernandes S., Zhu W.Z., Filice D., Muskheli V., Kim J., et al. Human ES-cell-derived cardiomyocytes electrically couple and suppress arrhythmias in injured hearts. Nature 2012, 489:322-325.
    • (2012) Nature , vol.489 , pp. 322-325
    • Shiba, Y.1    Fernandes, S.2    Zhu, W.Z.3    Filice, D.4    Muskheli, V.5    Kim, J.6
  • 79
    • 77953443251 scopus 로고    scopus 로고
    • Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome
    • Carvajal-Vergara X., Sevilla A., D'Souza S.L., Ang Y.S., Schaniel C., Lee D.F., et al. Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome. Nature 2010, 465:808-812.
    • (2010) Nature , vol.465 , pp. 808-812
    • Carvajal-Vergara, X.1    Sevilla, A.2    D'Souza, S.L.3    Ang, Y.S.4    Schaniel, C.5    Lee, D.F.6
  • 80
    • 77957729169 scopus 로고    scopus 로고
    • Patient-specific induced pluripotent stem-cell models for long-QT syndrome
    • Moretti A., Bellin M., Welling A., Jung C.B., Lam J.T., Bott-Flugel L., et al. Patient-specific induced pluripotent stem-cell models for long-QT syndrome. N Engl J Med 2010, 363:1397-1409.
    • (2010) N Engl J Med , vol.363 , pp. 1397-1409
    • Moretti, A.1    Bellin, M.2    Welling, A.3    Jung, C.B.4    Lam, J.T.5    Bott-Flugel, L.6
  • 82
    • 79952438377 scopus 로고    scopus 로고
    • Using induced pluripotent stem cells to investigate cardiac phenotypes in Timothy syndrome
    • Yazawa M., Hsueh B., Jia X., Pasca A.M., Bernstein J.A., Hallmayer J., et al. Using induced pluripotent stem cells to investigate cardiac phenotypes in Timothy syndrome. Nature 2011, 471:230-234.
    • (2011) Nature , vol.471 , pp. 230-234
    • Yazawa, M.1    Hsueh, B.2    Jia, X.3    Pasca, A.M.4    Bernstein, J.A.5    Hallmayer, J.6
  • 83
    • 84858040591 scopus 로고    scopus 로고
    • Model for long QT syndrome type 2 using human iPS cells demonstrates arrhythmogenic characteristics in cell culture
    • Lahti A.L., Kujala V.J., Chapman H., Koivisto A.P., Pekkanen-Mattila M., Kerkela E., et al. Model for long QT syndrome type 2 using human iPS cells demonstrates arrhythmogenic characteristics in cell culture. Dis Model Mech 2011, 5:220-230.
    • (2011) Dis Model Mech , vol.5 , pp. 220-230
    • Lahti, A.L.1    Kujala, V.J.2    Chapman, H.3    Koivisto, A.P.4    Pekkanen-Mattila, M.5    Kerkela, E.6
  • 84
    • 84860156650 scopus 로고    scopus 로고
    • Patient-specific induced pluripotent stem cells as a model for familial dilated cardiomyopathy
    • Sun N., Yazawa M., Liu J., Han L., Sanchez-Freire V., Abilez O.J., et al. Patient-specific induced pluripotent stem cells as a model for familial dilated cardiomyopathy. Sci Transl Med 2012, 4:130ra47.
    • (2012) Sci Transl Med , vol.4
    • Sun, N.1    Yazawa, M.2    Liu, J.3    Han, L.4    Sanchez-Freire, V.5    Abilez, O.J.6
  • 85
    • 84863213874 scopus 로고    scopus 로고
    • Cardiomyocytes derived from pluripotent stem cells recapitulate electrophysiological characteristics of an overlap syndrome of cardiac sodium channel disease
    • Davis R.P., Casini S., van den Berg C.W., Hoekstra M., Remme C.A., Dambrot C., et al. Cardiomyocytes derived from pluripotent stem cells recapitulate electrophysiological characteristics of an overlap syndrome of cardiac sodium channel disease. Circulation 2012, 125:3079-3091.
    • (2012) Circulation , vol.125 , pp. 3079-3091
    • Davis, R.P.1    Casini, S.2    van den Berg, C.W.3    Hoekstra, M.4    Remme, C.A.5    Dambrot, C.6
  • 86
    • 84858129398 scopus 로고    scopus 로고
    • Dantrolene rescues arrhythmogenic RYR2 defect in a patient-specific stem cell model of catecholaminergic polymorphic ventricular tachycardia
    • Jung C.B., Moretti A., Mederos y Schnitzler M., Iop L., Storch U., Bellin M., et al. Dantrolene rescues arrhythmogenic RYR2 defect in a patient-specific stem cell model of catecholaminergic polymorphic ventricular tachycardia. EMBO Mol Med 2011, 4:180-191.
    • (2011) EMBO Mol Med , vol.4 , pp. 180-191
    • Jung, C.B.1    Moretti, A.2    Mederos y Schnitzler, M.3    Iop, L.4    Storch, U.5    Bellin, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.