Dysregulation of subcutaneous adipose tissue blood flow in overweight postmenopausal women

Menopause

Volumn 17, Issue 2, 2010, Pages 365-371

  Andersson, Jonas ^a   Sjöström, Lars Göran ^a   Karlsson, Marcus ^a   Wiklund, Urban ^a   Hultin, Magnus ^a   Karpe, Fredrik ^b   Olsson, Tommy ^a  

^a UMEÅ UNIVERSITY HOSPITAL   (Sweden)

^b CHURCHILL HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DIMETHYLARGININASE; XENON;

ADIPOSE TISSUE BLOOD FLOW; ADRENERGIC SYSTEM; ADULT; ARTICLE; AUTONOMIC NERVOUS SYSTEM; BODY WEIGHT; CHOLINERGIC SYSTEM; CLINICAL ARTICLE; DISEASE ASSOCIATION; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM; FEMALE; HEALTH STATUS; HEART RATE VARIABILITY; HUMAN; MENOPAUSE; METABOLIC DISORDER; OBESITY; ORAL GLUCOSE TOLERANCE TEST; POSTMENOPAUSE; SUBCUTANEOUS FAT;

ADULT; AGED; AMIDOHYDROLASES; AUTONOMIC NERVOUS SYSTEM; ENDOTHELIUM, VASCULAR; FEMALE; HEART RATE; HUMANS; MIDDLE AGED; NITRIC OXIDE SYNTHASE; OBESITY, ABDOMINAL; OVERWEIGHT; POSTMENOPAUSE; REGIONAL BLOOD FLOW; SUBCUTANEOUS FAT; THYROID HORMONES;

EID: 77949345157     PISSN: 10723714     EISSN: None     Source Type: Journal    
DOI: 10.1097/gme.0b013e3181c12b26     Document Type: Article

References (32)

1. Brochu M, Starling RD, Tchernof A, Matthews DE, Garcia-Rubi E, Poehlman ET. Visceral adipose tissue is an independent correlate of glucose disposal in older obese postmenopausal women. J Clin Endocrinol Metab 2000;85:2378-2384.
2. Kopelman PG. Obesity as a medical problem. Nature 2000;404:635-643.
3. Okura T, Nakata Y, Yamabuki K, Tanaka K. Regional body composition changes exhibit opposing effects on coronary heart disease risk factors. Arterioscler Thromb Vasc Biol 2004;24:923-929.
4. Kotronen A, Yki-Jarvinen H. Fatty liver: a novel component of the metabolic syndrome. Arterioscler Thromb Vasc Biol 2008;28:27-38.
5. Volzke H, Schwarz S, Baumeister SE, et al. Menopausal status and hepatic steatosis in a general female population. Gut 2007;56:594-595.
6. Coppack SW, Fisher RM, Gibbons GF, et al. Postprandial substrate deposition in human forearm and adipose tissues in vivo. Clin Sci (Lond) 1990;79:339-348.
7. Summers LK, Samra JS, Humphreys SM, Morris RJ, Frayn KN. Subcutaneous abdominal adipose tissue blood flow: variation within and between subjects and relationship to obesity. Clin Sci (Lond) 1996;91: 679-683.
8. Ardilouze JL, Fielding BA, Currie JM, Frayn KN, Karpe F. Nitric oxide and A-adrenergic stimulation are major regulators of preprandial and postprandial subcutaneous adipose tissue blood flow in humans. Circulation 2004;109:47-52.
9. Boger RH, Bode-Boger SM, Szuba A, et al. Asymmetric dimethylargi-nine (ADMA): a novel risk factor for endothelial dysfunction: its role in hypercholesterolemia. Circulation 1998;98:1842-1847.
10. Ravani P, Tripepi G, Malberti F, Testa S, Mallamaci F, Zoccali C. Asymmetrical dimethylarginine predicts progression to dialysis and death in patients with chronic kidney disease: a competing risks modeling approach. J Am Soc Nephrol 2005;16:2449-2455.
11. Zoccali C, Bode-Boger S, Mallamaci F, et al. Plasma concentration of asymmetrical dimethylarginine and mortality in patients with end-stage renal disease: a prospective study. Lancet 2001;358:2113-2117.
12. Heart rate variability: standards of measurement, physiological interpretation and clinical use. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electro-physiology. Circulation 1996;93:1043-1065.
13. Bulow J. Measurement of adipose tissue blood flow. Methods Mol Biol 2001;155:281-293.
14. Karpe F, Fielding BA, Ardilouze JL, Ilic V, Macdonald IA, Frayn KN. Effects of insulin on adipose tissue blood flow in man. J Physiol 2002; 540:1087-1093.
15. Karpe F, Fielding BA, Ilic V, Macdonald IA, Summers LK, Frayn KN. Impaired postprandial adipose tissue blood flow response is related to aspects of insulin sensitivity. Diabetes 2002;51:2467-2473.
16. Marple SL. Digital Spectral Analysis With Applications. Englewood Cliffs, NJ: Prentice-Hall, 1987.
17. Nunan D, Donovan G, Jakovljevic DG, Hodges LD, Sandercock GR, Brodie DA. Validity and reliability of short-term heart-rate variability from the Polar S810. Med Sci Sports Exerc 2009;41:243-250.
18. Pinna GD, Maestri R, Torunski A, et al. Heart rate variability measures: a fresh look at reliability. Clin Sci (Lond) 2007;113:131-140.
19. Wiklund U, Koskinen LO, Niklasson U, Bjerle P, Elfversson J. Endo-scopic transthoracic sympathicotomy affects the autonomic modulation of heart rate in patients with palmar hyperhidrosis. Acta Neurochir (Wien) 2000;142:691-696.
20. Teerlink T. HPLC analysis of ADMA and other methylated L-arginine analogs in biological fluids. J Chromatogr B Analyt Technol Biomed Life Sci 2007;851:21-29.
21. Gasparo D. Angiotensin II and nitric oxide interaction. Heart Fail Rev 2002;7:347-358.
22. Goossens GH, McQuaid SE, Dennis AL, et al. Angiotensin II: a major regulator of subcutaneous adipose tissue blood flow in humans. J Physiol 2006;571:451-460.
23. Bulow J, Astrup A, Christensen NJ, Kastrup J. Blood flow in skin, subcutaneous adipose tissue and skeletal muscle in the forearm of normal man during an oral glucose load. Acta Physiol Scand 1987;130: 657-661.
24. Lauer MS. Autonomic function and prognosis. Cleve Clin J Med 2009; 76:S18-S22.
25. Mersmann HJ. Acute changes in blood flow in pigs infused with A-adrenergic agonists. J Anim Sci 1989;67:2913-2920.
26. Laederach-Hofmann K, Mussgay L, Ruddel H. Autonomic cardiovascular regulation in obesity. J Endocrinol 2000;164:59-66.
27. Tentolouris N, Tsigos C, Perea D, et al. Differential effects of high-fat and high-carbohydrate isoenergetic meals on cardiac autonomic nervous system activity in lean and obese women. Metabolism 2003;52:1426-1432.
28. Vollenweider P, Randin D, Tappy L, Jequier E, Nicod P, Scherrer U. Impaired insulin-induced sympathetic neural activation and vasodilation in skeletal muscle in obese humans. J Clin Invest 1994;93:2365-2371.
29. Frayn KN. Adipose tissue as a buffer for daily lipid flux. Diabetologia 2002;45:1201-1210.
30. Jensen MD. Role of body fat distribution and the metabolic complications of obesity. J Clin Endocrinol Metab 2008;93:S57-S63.
31. Horowitz JF, Klein S. Whole body and abdominal lipolytic sensitivity to epinephrine is suppressed in upper body obese women. Am J Physiol Endocrinol Metab 2000;278:E1144-E1152.
32. Tan GD, Goossens GH, Humphreys SM, Vidal H, Karpe F. Upper and lower body adipose tissue function: a direct comparison of fat mobilization in humans. Obes Res 2004;12:114-118.