Synthesis and biological evaluation of arctigenin ester and ether derivatives as activators of AMPK

Bioorganic and Medicinal Chemistry

Volumn 21, Issue 13, 2013, Pages 3882-3893

  Shen, Sida ^a   Zhuang, Jingjing ^a   Chen, Yijia ^b   Lei, Min ^b   Chen, Jing ^b,c   Shen, Xu ^a,b   Hu, Lihong ^a,b  

^a EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^c PEKING UNIVERSITY   (China)

Author keywords

9 Deoxy arctigenin; AMPK 2 (3,4 Dimethoxyphenyl)ethyl; Arctigenin

Indexed keywords

4 (3 METHOXYPHENETHOXY)9 DEOXY ARCTIGENIN; 4 (3,4 DIMETHOXYPHENETHOXY) 9 DEOXY ARCTIGENIN; 4 (3,4 DIMETHOXYPHENETHOXY)ARCTIGENIN; 4 (3,4,5 TRIMETHOXYPHENETHOXY) 9 DEOXY ARCTIGENIN; 4 (VALERLOXY)ARCTIGENIN; 4 ACETOXY ARCTIGENIN; ARCTIGENIN; ENZYME INDUCING AGENT; UNCLASSIFIED DRUG; ESTER; FURAN DERIVATIVE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; LIGNAN;

ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG DETERMINATION; DRUG EFFECT; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; MYOBLAST; STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL LINE; CHEMISTRY; DRUG EFFECTS; ENZYMOLOGY; METABOLISM; PHOSPHORYLATION; SYNTHESIS;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; CELL LINE; ESTERS; FURANS; LIGNANS; MYOBLASTS; PHOSPHORYLATION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84878580765     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2013.04.010     Document Type: Article

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