The diverse therapeutic actions of pregabalin: Is a single mechanism responsible for several pharmacological activities?

Trends in Pharmacological Sciences

Volumn 34, Issue 6, 2013, Pages 332-339

  Stahl, Stephen M ^a   Porreca, Frank ^b   Taylor, Charles P ^c   Cheung, Raymond ^d   Thorpe, Andrew J ^d   Clair, Andrew ^d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^c CpTaylor Consulting   (United States)

^d PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; ALPHA 2 ADRENERGIC RECEPTOR; CALCIUM CHANNEL N TYPE; CALCIUM CHANNEL P TYPE; CALCIUM CHANNEL Q TYPE; GABAPENTIN; GLUTAMIC ACID; GLUTAMINE; PLACEBO; PREGABALIN; SEROTONIN 3 RECEPTOR; SEROTONIN NORADRENALIN REUPTAKE INHIBITOR; SEROTONIN UPTAKE INHIBITOR; THROMBOSPONDIN; VOLTAGE GATED CALCIUM CHANNEL;

ADD ON THERAPY; AMBLYOPIA; ANTINOCICEPTION; ANXIETY DISORDER; ATAXIA; BALANCE DISORDER; BLURRED VISION; BRAIN STEM; CHRONIC PAIN; COGNITIVE DEFECT; CONSTIPATION; COORDINATION DISORDER; DIABETIC NEUROPATHY; DIPLOPIA; DIZZINESS; DROWSINESS; DRUG DOSE INCREASE; DRUG DOSE TITRATION; EUPHORIA; FIBROMYALGIA; FOCAL EPILEPSY; GABAERGIC TRANSMISSION; GENERALIZED ANXIETY DISORDER; HUMAN; HYPERALGESIA; LOCUS CERULEUS; NEOCORTEX; NEUROMODULATION; NEUROPATHIC PAIN; NEUROTRANSMITTER RELEASE; NONHUMAN; OVERACTIVE BLADDER; PERIPHERAL EDEMA; POSTHERPETIC NEURALGIA; PRIORITY JOURNAL; REM SLEEP; RESTLESS LEGS SYNDROME; REVIEW; SEIZURE THRESHOLD; SIDE EFFECT; SLEEP DISORDER; SLOW WAVE SLEEP; SOCIAL PHOBIA; SOMNOLENCE; SPINAL CORD; SPREADING CORTICAL DEPRESSION; SYNAPSE; TONIC CLONIC SEIZURE; TRAUMATIC EPILEPSY; TREMOR; VERTIGO; WEIGHT GAIN;

ANIMALS; CALCIUM CHANNEL BLOCKERS; CENTRAL NERVOUS SYSTEM DISEASES; GAMMA-AMINOBUTYRIC ACID; HUMANS; SYNAPTIC TRANSMISSION;

EID: 84878564545     PISSN: 01656147     EISSN: 18733735     Source Type: Journal    
DOI: 10.1016/j.tips.2013.04.001     Document Type: Review

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