Central sensitization and CaVα2δ ligands in chronic pain syndromes: Pathologic processes and pharmacologic effect

Journal of Pain

Volumn 11, Issue 12, 2010, Pages 1241-1249

  Tuchman, Michael ^a,b   Barrett, Jeannette A ^b   Donevan, Sean ^b   Hedberg, Thomas G ^c   Taylor, Charles P ^d  

^a Palm Beach Neurological Center   (United States)

^b PFIZER INC   (United States)

^c ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^d CpTaylor Consulting   (United States)

Author keywords

Central sensitization; Chronic pain; Gabapentin; Plasticity; Pregabalin

Indexed keywords

CALCIUM CHANNEL; CALCIUM CHANNEL V ALPHA2DELTA; GABAPENTIN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; PREGABALIN; SODIUM CHANNEL BLOCKING AGENT; UNCLASSIFIED DRUG;

ALLODYNIA; CHRONIC PAIN; CONFORMATIONAL TRANSITION; DRUG MECHANISM; HUMAN; HYPERALGESIA; LONG TERM POTENTIATION; NEUROPHYSIOLOGY; NEUROTRANSMITTER RELEASE; NONHUMAN; PROTEIN EXPRESSION; REVIEW; SPINAL CORD DORSAL HORN;

EID: 78649677578     PISSN: 15265900     EISSN: 15288447     Source Type: Journal    
DOI: 10.1016/j.jpain.2010.02.024     Document Type: Article

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