Pregabalin increases slow-wave sleep and may improve attention in patients with partial epilepsy and insomnia

Epilepsy and Behavior

Volumn 23, Issue 4, 2012, Pages 422-425

  Bazil, C W ^a   Dave, J ^a   Cole, J ^b   Stalvey, J ^a   Drake, E ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b NEW JERSEY NEUROSCIENCE INSTITUTE   (United States)

Author keywords

Anticonvulsant drug; Attention; Epilepsy; Insomnia; Polysomnography; Pregabalin; Slow wave sleep

Indexed keywords

ETIRACETAM; LAMOTRIGINE; OXCARBAZEPINE; PHENYTOIN; PLACEBO; PREGABALIN; TOPIRAMATE; ZONISAMIDE;

ADULT; ARTICLE; ATTENTION; BRIEF VISUOSPATIAL MEMORY TEST REVISED; CLINICAL ARTICLE; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; DRUG EFFECT; FEMALE; FOCAL EPILEPSY; HUMAN; INSOMNIA; LEARNING TEST; MALE; NEUROPSYCHOLOGICAL TEST; POLYSOMNOGRAPHY; PSYCHOMOTOR ACTIVITY; PSYCHOMOTOR VIGILANCE TASK; RANDOMIZED CONTROLLED TRIAL; REY AUDITORY VERBAL LEARNING TEST; SLEEP QUALITY; SLOW WAVE SLEEP; VERBAL FLUENCY FROM THE DELIS KAPLAN EXECUTIVE FUNCTION SYSTEM;

ADOLESCENT; ADULT; ANTICONVULSANTS; ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; CROSS-OVER STUDIES; DOUBLE-BLIND METHOD; ELECTROENCEPHALOGRAPHY; ELECTROMYOGRAPHY; EPILEPSIES, PARTIAL; FEMALE; GAMMA-AMINOBUTYRIC ACID; HUMANS; MALE; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; POLYSOMNOGRAPHY; SLEEP; SLEEP INITIATION AND MAINTENANCE DISORDERS; YOUNG ADULT;

EID: 84859161404     PISSN: 15255050     EISSN: 15255069     Source Type: Journal    
DOI: 10.1016/j.yebeh.2012.02.005     Document Type: Article

References (32)

1. Ohayon M.M., Roth T. What are the contributing factors for insomnia in the general population?. J Psychosom Res 2001, 51(6):745-755.
2. Mitler M.M., Carskadon M.A., Czeisler C.A., Dement W.C., Dinges D.F., Graeber R.C. Catastrophes, sleep, and public policy: consensus report. Sleep 1988, 11(1):100-109.
3. Morin C.M., Belanger L., Bernier F. Correlates of benzodiazepine use in individuals with insomnia. Sleep Med 2004, 5(5):457-462.
4. Roehrs T., Roth T. 'Hypnotic' prescription patterns in a large managed-care population. Sleep Med 2004, 5(5):463-466.
5. Stickgold R., Hobson J.A., Fosse R., Fosse M. Sleep, learning, and dreams: off-line memory reprocessing. Science 2001, 294(5544):1052-1057.
6. Walker M.P., Stickgold R. Sleep-dependent learning and memory consolidation. Neuron 2004, 44(1):121-133.
7. Walsh J.K., Randazzo A.C., Stone K., et al. Tiagabine is associated with sustained attention during sleep restriction: evidence for the value of slow-wave sleep enhancement?. Sleep 2006, 29(4):433-443.
8. Ellenbogen J.M., Hulbert J.C., Stickgold R., Dinges D.F., Thompson-Schill S.L. Interfering with theories of sleep and memory: sleep, declarative memory, and associative interference. Curr Biol 2006, 16(13):1290-1294.
9. de Weerd A., de Haas S., Otte A., et al. Subjective sleep disturbance in patients with partial epilepsy: a questionnaire-based study on prevalence and impact on quality of life. Epilepsia 2004, 45(11):1397-1404.
10. Xu X., Brandenburg N.A., McDermott A.M., Bazil C.W. Sleep disturbances reported by refractory partial-onset epilepsy patients receiving polytherapy. Epilepsia 2006, 47(7):1176-1183.
11. Sabatowski R., Galvez R., Cherry D.A., et al. Pregabalin reduces pain and improves sleep and mood disturbances in patients with post-herpetic neuralgia: results of a randomised, placebo-controlled clinical trial. Pain 2004, 109(1-2):26-35.
12. Hindmarch I., Dawson J., Stanley N. A double-blind study in healthy volunteers to assess the effects on sleep of pregabalin compared with alprazolam and placebo. Sleep 2005, 28(2):187-193.
13. de Haas S., Otte A., de Weerd A., van Erp G., Cohen A., van Gerven J. Exploratory polysomnographic evaluation of pregabalin on sleep disturbance in patients with epilepsy. J Clin Sleep Med 2007, 3(5):473-478.
14. Bazil C.W., Castro L.H., Walczak T.S. Reduction of rapid eye movement sleep by diurnal and nocturnal seizures in temporal lobe epilepsy. Arch Neurol 2000, 57(3):363-368.
15. Wolf P., Roder-Wanner U.U., Brede M. Influence of therapeutic phenobarbital and phenytoin medication on the polygraphic sleep of patients with epilepsy. Epilepsia 1984, 25(4):467-475.
16. Drake M.E., Pakalnis A., Bogner J.E., Andrews J.M. Outpatient sleep recording during antiepileptic drug monotherapy. Clin Electroencephalogr 1990, 21(3):170-173.
17. Legros B., Bazil C.W. Effects of antiepileptic drugs on sleep architecture: a pilot study. Sleep Med 2003, 4(1):51-55.
18. Placidi F., Diomedi M., Scalise A., Marciani M.G., Romigi A., Gigli G.L. Effect of anticonvulsants on nocturnal sleep in epilepsy. Neurology 2000, 54(5 Suppl 1):S25-S32.
19. Yang J.D., Elphick M., Sharpley A.L., Cowen P.J. Effects of carbamazepine on sleep in healthy volunteers. Biol Psychiatry 1989, 26(3):324-328.
20. Foldvary N., Perry M., Lee J., Dinner D., Morris H.H. The effects of lamotrigine on sleep in patients with epilepsy. Epilepsia 2001, 42(12):1569-1573.
21. Foldvary-Schaefer N., De Leon Sanchez I., Karafa M., Mascha E., Dinner D., Morris H.H. Gabapentin increases slow-wave sleep in normal adults. Epilepsia 2002, 43(12):1493-1497.
22. Bazil C., Battista J., Basner R. Gabapentin improves sleep in the presence of alcohol. J Clin Sleep Med 2005, 1:284-287.
23. Mathias S., Wetter T.C., Steiger A., Lancel M. The GABA uptake inhibitor tiagabine promotes slow wave sleep in normal elderly subjects. Neurobiol Aging 2001, 22(2):247-253.
24. Walsh J.K., Randazzo A.C., Frankowski S., Shannon K., Schweitzer P.K., Roth T. Dose-response effects of tiagabine on the sleep of older adults. Sleep 2005, 28(6):673-676.
25. Bell C., Vanderlinden H., Hiersemenzel R., Otoul C., Nutt D., Wilson S. The effects of levetiracetam on objective and subjective sleep parameters in healthy volunteers and patients with partial epilepsy. J Sleep Res 2002, 11(3):255-263.
26. Cicolin A., Magliola U., Giordano A., Terreni A., Bucca C., Mutani R. Effects of levetiracetam on nocturnal sleep and daytime vigilance in healthy volunteers. Epilepsia 2006, 47(1):82-85.
27. Salinsky M.C., Oken B.S., Binder L.M. Assessment of drowsiness in epilepsy patients receiving chronic antiepileptic drug therapy. Epilepsia 1996, 37(2):181-187.
28. Romigi A., Izzi F., Marciani M.G., et al. Pregabalin as add-on therapy induces REM sleep enhancement in partial epilepsy: a polysomnographic study. Eur J Neurol 2009, 16(1):70-75.
29. Sammaritano M., Sherwin A. Effect of anticonvulsants on sleep. Neurology 2000, 54(5 Suppl 1):S16-S24.
30. Pande A.C., Crockatt J.G., Feltner D.E., et al. Pregabalin in generalized anxiety disorder: a placebo-controlled trial. Am J Psychiatry 2003, 160(3):533-540.
31. Arroyo S., Anhut H., Kugler A.R., et al. Pregabalin add-on treatment: a randomized, double-blind, placebo-controlled, dose-response study in adults with partial seizures. Epilepsia 2004, 45(1):20-27.
32. French J.A., Kugler A.R., Robbins J.L., Knapp L.E., Garofalo E.A. Dose-response trial of pregabalin adjunctive therapy in patients with partial seizures. Neurology 2003, 60(10):1631-1637.