Inhibition of focal adhesion kinase (FAK) activity prevents anchorage-independent ovarian carcinoma cell growth and tumor progression

Clinical and Experimental Metastasis

Volumn 30, Issue 5, 2013, Pages 579-594

  Ward, Kristy K ^a   Tancioni, Isabelle ^a   Lawson, Christine ^a   Miller, Nichol L G ^a   Jean, Christine ^a   Chen, Xiao Lei ^a   Uryu, Sean ^a   Kim, Josephine ^a   Tarin, David ^b   Stupack, Dwayne G ^a   Plaxe, Steven C ^a   Schlaepfer, David D ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Anchorage independent cell growth; Cell survival; Focal adhesion kinase; Metastasis; Orthotopic tumor growth; Ovarian cancer; Syngeneic tumor model

Indexed keywords

FOCAL ADHESION KINASE; PF 562271; PROTEIN TYROSINE KINASE;

ANCHORAGE INDEPENDENT GROWTH; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER GROWTH; CARCINOMA CELL; CELL ISOLATION; CELL SURVIVAL; COMPARATIVE STUDY; DISTANT METASTASIS; DRUG CYTOTOXICITY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; FEMALE; GENE SILENCING; HUMAN; HUMAN CELL; IN VITRO STUDY; MOUSE; NONHUMAN; ONCOGENE SRC; ORTHOTOPIC TRANSPLANTATION; OVARY CARCINOMA; PERITONEUM METASTASIS; PROTEIN PHOSPHORYLATION; TUMOR VOLUME;

CELL DIVISION; DISEASE PROGRESSION; FEMALE; FOCAL ADHESION PROTEIN-TYROSINE KINASES; HUMANS; OVARIAN NEOPLASMS; PROTEIN KINASE INHIBITORS; RNA, MESSENGER;

EID: 84878549607     PISSN: 02620898     EISSN: 15737276     Source Type: Journal    
DOI: 10.1007/s10585-012-9562-5     Document Type: Article

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