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Volumn 127, Issue 1, 2012, Pages 70-74

Phase II evaluation of dasatinib in the treatment of recurrent or persistent epithelial ovarian or primary peritoneal carcinoma: A gynecologic oncology group study

Author keywords

Cancer; Dasatinib; Inhibition; Ovarian; SRC

Indexed keywords

BIOLOGICAL MARKER; CELL FREE DNA; DASATINIB; DNA; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; SOMATOMEDIN BINDING PROTEIN 2; UNCLASSIFIED DRUG; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 2; VASCULOTROPIN RECEPTOR 3;

EID: 84865676963     PISSN: 00908258     EISSN: 10956859     Source Type: Journal    
DOI: 10.1016/j.ygyno.2012.06.009     Document Type: Article
Times cited : (55)

References (34)
  • 1
    • 79959774261 scopus 로고    scopus 로고
    • Recent progress in the diagnosis and treatment of ovarian cancer
    • D. Jelovac, and D.K. Armstrong Recent progress in the diagnosis and treatment of ovarian cancer CA Cancer J Clin 61 2011 183 203
    • (2011) CA Cancer J Clin , vol.61 , pp. 183-203
    • Jelovac, D.1    Armstrong, D.K.2
  • 2
    • 0037150728 scopus 로고    scopus 로고
    • Src in cancer: Deregulation and consequences for cell behaviour
    • M.C. Frame Src in cancer: deregulation and consequences for cell behaviour Biochim Biophys Acta 1602 2002 114 130
    • (2002) Biochim Biophys Acta , vol.1602 , pp. 114-130
    • Frame, M.C.1
  • 4
    • 2942618768 scopus 로고    scopus 로고
    • A renaissance for SRC
    • T.J. Yeatman A renaissance for SRC Nat Rev Cancer 4 2004 470 480
    • (2004) Nat Rev Cancer , vol.4 , pp. 470-480
    • Yeatman, T.J.1
  • 5
    • 0041422435 scopus 로고    scopus 로고
    • Src tyrosine kinase promotes survival and resistance to chemotherapeutics in a mouse ovarian cancer cell line
    • Y. Pengetnze, M. Steed, K.F. Roby, P.F. Terranova, and C.C. Taylor Src tyrosine kinase promotes survival and resistance to chemotherapeutics in a mouse ovarian cancer cell line Biochem Biophys Res Commun 309 2003 377 383
    • (2003) Biochem Biophys Res Commun , vol.309 , pp. 377-383
    • Pengetnze, Y.1    Steed, M.2    Roby, K.F.3    Terranova, P.F.4    Taylor, C.C.5
  • 6
    • 14844333242 scopus 로고    scopus 로고
    • Src inhibition enhances paclitaxel cytotoxicity in ovarian cancer cells by caspace-9 independent activation of caspace-3
    • T. Chen, Y. Pengetnze, and C.C. Taylor Src inhibition enhances paclitaxel cytotoxicity in ovarian cancer cells by caspace-9 independent activation of caspace-3 Mol Cancer Ther 4 2005 217 224
    • (2005) Mol Cancer Ther , vol.4 , pp. 217-224
    • Chen, T.1    Pengetnze, Y.2    Taylor, C.C.3
  • 7
    • 70949093847 scopus 로고    scopus 로고
    • Effects of Src kinase inhibition induced by dasatinib in non-small cell lung cancer cell lines treated with cisplatin
    • P. Ceppi, M. Papotti, V. Monica, M. Lo Iacono, S. Saviozzi, and M. Pautasso Effects of Src kinase inhibition induced by dasatinib in non-small cell lung cancer cell lines treated with cisplatin Mol Cancer Ther 8 2009 3066 3074
    • (2009) Mol Cancer Ther , vol.8 , pp. 3066-3074
    • Ceppi, P.1    Papotti, M.2    Monica, V.3    Lo Iacono, M.4    Saviozzi, S.5    Pautasso, M.6
  • 8
    • 0032812095 scopus 로고    scopus 로고
    • Decreased Src tyrosine kinase activity inhibits malignant human ovarian cancer tumor growth in a nude mouse model
    • J.R. Wiener, K. Nakano, R.P. Kruzelock, C.D. Bucana, R.C. Bast Jr., and G.E. Gallick Decreased Src tyrosine kinase activity inhibits malignant human ovarian cancer tumor growth in a nude mouse model Clin Cancer Res 5 1999 2164 2170
    • (1999) Clin Cancer Res , vol.5 , pp. 2164-2170
    • Wiener, J.R.1    Nakano, K.2    Kruzelock, R.P.3    Bucana, C.D.4    Bast, Jr.R.C.5    Gallick, G.E.6
  • 9
    • 34447499062 scopus 로고    scopus 로고
    • Novel approaches in advancing the treatment of epithelial ovarian cancer: The role of angiogenesis inhibition
    • L. Martin, and R. Schilder Novel approaches in advancing the treatment of epithelial ovarian cancer: the role of angiogenesis inhibition J Clin Oncol 25 2007 2894 2901
    • (2007) J Clin Oncol , vol.25 , pp. 2894-2901
    • Martin, L.1    Schilder, R.2
  • 10
    • 33749003219 scopus 로고    scopus 로고
    • Antiangiogenic and antitumor effects of SRC inhibition in ovarian cancer
    • L.Y. Han, C.N. Landen, J.G. Trevino, J. Halder, Y.G. Lin, and A.A. Kamat Antiangiogenic and antitumor effects of SRC inhibition in ovarian cancer Cancer Res 66 2006 8633 8639
    • (2006) Cancer Res , vol.66 , pp. 8633-8639
    • Han, L.Y.1    Landen, C.N.2    Trevino, J.G.3    Halder, J.4    Lin, Y.G.5    Kamat, A.A.6
  • 11
    • 36849019301 scopus 로고    scopus 로고
    • Phase II trial of bevacizumab in persistent or recurrent epithelial ovarian cancer or primary peritoneal cancer: A Gynecologic Oncology Group Study
    • R.A. Burger, M.W. Sill, B.J. Monk, B.E. Greer, and J.I. Sorosky Phase II trial of bevacizumab in persistent or recurrent epithelial ovarian cancer or primary peritoneal cancer: a Gynecologic Oncology Group Study J Clin Oncol 25 2007 5165 5171
    • (2007) J Clin Oncol , vol.25 , pp. 5165-5171
    • Burger, R.A.1    Sill, M.W.2    Monk, B.J.3    Greer, B.E.4    Sorosky, J.I.5
  • 13
    • 4644315256 scopus 로고    scopus 로고
    • Biological significance of focal adhesion kinase in ovarian cancer: Role in migration and invasion
    • A.K. Sood, J.E. Coffin, G.B. Schneider, M.S. Fletcher, B.R. DeYoung, and L.M. Gruman Biological significance of focal adhesion kinase in ovarian cancer: role in migration and invasion Am J Pathol 165 2004 1087 1095
    • (2004) Am J Pathol , vol.165 , pp. 1087-1095
    • Sood, A.K.1    Coffin, J.E.2    Schneider, G.B.3    Fletcher, M.S.4    Deyoung, B.R.5    Gruman, L.M.6
  • 14
    • 0037145037 scopus 로고    scopus 로고
    • Integrins: Bidirectional, allosteric signaling machines
    • R.O. Hynes Integrins: bidirectional, allosteric signaling machines Cell 110 2002 673 687
    • (2002) Cell , vol.110 , pp. 673-687
    • Hynes, R.O.1
  • 15
    • 75749103348 scopus 로고    scopus 로고
    • Src signaling in cancer invasion
    • M. Guarino Src signaling in cancer invasion J Cell Physiol 223 2010 14 26
    • (2010) J Cell Physiol , vol.223 , pp. 14-26
    • Guarino, M.1
  • 16
    • 85047696594 scopus 로고    scopus 로고
    • Src kinase contributes to the metastatic spread of carcinoma cells
    • B. Boyer, Y. Bourgeois, and M.F. Poupon Src kinase contributes to the metastatic spread of carcinoma cells Oncogene 21 2002 2347 2356
    • (2002) Oncogene , vol.21 , pp. 2347-2356
    • Boyer, B.1    Bourgeois, Y.2    Poupon, M.F.3
  • 17
    • 27544441125 scopus 로고    scopus 로고
    • Simultaneous expression of caveolin-1 and E-cadherin in ovarian carcinoma cells stabilizes adherens junctions through inhibition of Src-related kinases
    • S. Miotti, A. Tomassetti, I. Facetti, E. Sanna, V. Berno, and S. Canevari Simultaneous expression of caveolin-1 and E-cadherin in ovarian carcinoma cells stabilizes adherens junctions through inhibition of Src-related kinases Am J Pathol 167 2005 1411 1427
    • (2005) Am J Pathol , vol.167 , pp. 1411-1427
    • Miotti, S.1    Tomassetti, A.2    Facetti, I.3    Sanna, E.4    Berno, V.5    Canevari, S.6
  • 19
    • 3142676436 scopus 로고    scopus 로고
    • Overriding imatinib resistance with a novel ABL kinase inhibitor
    • N.P. Shah, C. Tran, F.Y. Lee, P. Chen, D. Norris, and C.L. Sawyers Overriding imatinib resistance with a novel ABL kinase inhibitor Science 305 2004 399 401
    • (2004) Science , vol.305 , pp. 399-401
    • Shah, N.P.1    Tran, C.2    Lee, F.Y.3    Chen, P.4    Norris, D.5    Sawyers, C.L.6
  • 20
    • 19944428353 scopus 로고    scopus 로고
    • Discovery of N-(2-Chloro-6-methyl-phenyl-2-(6-(4-(2-hydroxyethyl)- piperazin-1-yl)-2-methylpyrimidin-4-ylamino)thiazole-5-carboxamide (BMS-354825), a dual Src-Abl kinase inhibitor with potent antitumor activity in preclinical assays
    • L.J. Lombardo, F.Y. Lee, P. Chen, D. Norris, J.C. Barrish, and K. Behnia Discovery of N-(2-Chloro-6-methyl-phenyl-2-(6-(4-(2-hydroxyethyl)-piperazin-1- yl)-2-methylpyrimidin-4-ylamino)thiazole-5-carboxamide (BMS-354825), a dual Src-Abl kinase inhibitor with potent antitumor activity in preclinical assays J Med Chem 47 2004 6658 6661
    • (2004) J Med Chem , vol.47 , pp. 6658-6661
    • Lombardo, L.J.1    Lee, F.Y.2    Chen, P.3    Norris, D.4    Barrish, J.C.5    Behnia, K.6
  • 21
    • 77956072809 scopus 로고    scopus 로고
    • Dasatinib: A potent SRC inhibitor in clinical development for the treatment of solid tumors
    • J. Araujo, and C. Logothetis Dasatinib: a potent SRC inhibitor in clinical development for the treatment of solid tumors Cancer Treat Rev 36 2010 492 500
    • (2010) Cancer Treat Rev , vol.36 , pp. 492-500
    • Araujo, J.1    Logothetis, C.2
  • 22
    • 0034594628 scopus 로고    scopus 로고
    • New guidelines to evaluate the response to treatment in solid tumors: European Organization for Research and Treatment of Cancer. National Cancer Institute of Canada
    • P. Therasse, S.G. Arbuck, E.A. Eisenhauer, J. Wanders, R.S. Kaplan, and L. Rubinstein New guidelines to evaluate the response to treatment in solid tumors: European Organization for Research and Treatment of Cancer. National Cancer Institute of Canada J Natl Cancer Inst 92 2000 205 216
    • (2000) J Natl Cancer Inst , vol.92 , pp. 205-216
    • Therasse, P.1    Arbuck, S.G.2    Eisenhauer, E.A.3    Wanders, J.4    Kaplan, R.S.5    Rubinstein, L.6
  • 23
    • 33845723163 scopus 로고    scopus 로고
    • Dasatinib (BMS-354825) pharmacokinetics and pharmacodynamic biomarkers in animal models predict optimal clinical exposure
    • F.R. Luo, Z. Yang, A. Camuso, R. Smykla, K. McGlinchey, and K. Fager Dasatinib (BMS-354825) pharmacokinetics and pharmacodynamic biomarkers in animal models predict optimal clinical exposure Clin Cancer Res 12 2006 7180 7186
    • (2006) Clin Cancer Res , vol.12 , pp. 7180-7186
    • Luo, F.R.1    Yang, Z.2    Camuso, A.3    Smykla, R.4    McGlinchey, K.5    Fager, K.6
  • 24
    • 51849140016 scopus 로고    scopus 로고
    • Identification and validation of phospho-SRC, a novel and potential pharmacodynamic biomarker for dasatinib (SPRYCEL™), a multi-targeted kinase inhibitor
    • F.R. Luo, Y.C. Barrett, Z. Yang, A. Camuso, K. McGlinchey, and M.L. Wen Identification and validation of phospho-SRC, a novel and potential pharmacodynamic biomarker for dasatinib (SPRYCEL™), a multi-targeted kinase inhibitor Cancer Chemother Pharmacol 62 2008 1065 1074
    • (2008) Cancer Chemother Pharmacol , vol.62 , pp. 1065-1074
    • Luo, F.R.1    Barrett, Y.C.2    Yang, Z.3    Camuso, A.4    McGlinchey, K.5    Wen, M.L.6
  • 25
    • 80052573270 scopus 로고    scopus 로고
    • A method for utilizing bivariate efficacy outcome measures to screen agents for activity in the 2-stage phase II clinical trials
    • Department of Biostatistics, University of Buffalo. Website
    • Sill MW, Yothers GA. A method for utilizing bivariate efficacy outcome measures to screen agents for activity in the 2-stage phase II clinical trials. Technical Report 06-08, Department of Biostatistics, University of Buffalo. Website: http://sphhp.buffalo.edu/biostat/research/techreports/index.php, 2008
    • (2008) Technical Report 06-08
    • Sill, M.W.1    Yothers, G.A.2
  • 26
    • 33947512381 scopus 로고    scopus 로고
    • An integrated genomic-based approach to individualized treatment of patients with advanced-stage ovarian cancer
    • H.K. Dressman, A. Berchuck, G. Chan, J. Zhai, A. Bild, and R. Sayer An integrated genomic-based approach to individualized treatment of patients with advanced-stage ovarian cancer J Clin Oncol 25 2007 517 525
    • (2007) J Clin Oncol , vol.25 , pp. 517-525
    • Dressman, H.K.1    Berchuck, A.2    Chan, G.3    Zhai, J.4    Bild, A.5    Sayer, R.6
  • 27
    • 31144459985 scopus 로고    scopus 로고
    • Oncogenic pathway signatures in human cancers as a guide to targeted therapies
    • A.H. Bild, G. Yao, J.T. Chang, Q. Wang, A. Potti, and D. Chasse Oncogenic pathway signatures in human cancers as a guide to targeted therapies Nature 439 2006 353 357
    • (2006) Nature , vol.439 , pp. 353-357
    • Bild, A.H.1    Yao, G.2    Chang, J.T.3    Wang, Q.4    Potti, A.5    Chasse, D.6
  • 28
    • 70449533848 scopus 로고    scopus 로고
    • Activity of the multikinase inhibitor dasatinib against ovarian cancer cells
    • G.E. Konecny, R. Glas, J. Dering, K. Manivong, J. Qi, and R.S. Finn Activity of the multikinase inhibitor dasatinib against ovarian cancer cells Br J Cancer 101 2009 1699 1708
    • (2009) Br J Cancer , vol.101 , pp. 1699-1708
    • Konecny, G.E.1    Glas, R.2    Dering, J.3    Manivong, K.4    Qi, J.5    Finn, R.S.6
  • 29
    • 79952816751 scopus 로고    scopus 로고
    • Dasatinib (BMS-35482) has synergistic activity with paclitaxel and carboplatin in ovarian cancer cells
    • D. Teoh, T.A. Yeni, J.M. Tubatt, D.J. Adams, L. Grace, and M.D. Starr Dasatinib (BMS-35482) has synergistic activity with paclitaxel and carboplatin in ovarian cancer cells Gynecol Oncol 121 2011 187 192
    • (2011) Gynecol Oncol , vol.121 , pp. 187-192
    • Teoh, D.1    Yeni, T.A.2    Tubatt, J.M.3    Adams, D.J.4    Grace, L.5    Starr, M.D.6
  • 30
    • 73149115110 scopus 로고    scopus 로고
    • Phase II study of dasatinib in patients with metastatic castration-resistant prostate cancer
    • E.Y. Yu, G. Wilding, E. Posadas, M. Gross, S. Culine, and C. Massard Phase II study of dasatinib in patients with metastatic castration-resistant prostate cancer Clin Cancer Res 15 2009 7421 7428
    • (2009) Clin Cancer Res , vol.15 , pp. 7421-7428
    • Yu, E.Y.1    Wilding, G.2    Posadas, E.3    Gross, M.4    Culine, S.5    Massard, C.6
  • 31
    • 79956283619 scopus 로고    scopus 로고
    • Current status of Src inhibitors in solid tumors
    • L.N. Puls, M. Eadens, and W. Messersmith Current status of Src inhibitors in solid tumors Oncologist 16 2011 566 578
    • (2011) Oncologist , vol.16 , pp. 566-578
    • Puls, L.N.1    Eadens, M.2    Messersmith, W.3
  • 33
    • 84855462695 scopus 로고    scopus 로고
    • STAT-5A-mediated SOCS2 expression regulates JAK2 and STAT3 activity following c-SRC inhibition in head and neck squamous carcinoma
    • B. Sen, S. Peng, D.M. Woods, I. Wistuba, D. Bell, and A.K. El-Naggar STAT-5A-mediated SOCS2 expression regulates JAK2 and STAT3 activity following c-SRC inhibition in head and neck squamous carcinoma Clin Cancer Res 18 2012 127 139
    • (2012) Clin Cancer Res , vol.18 , pp. 127-139
    • Sen, B.1    Peng, S.2    Woods, D.M.3    Wistuba, I.4    Bell, D.5    El-Naggar, A.K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.