An insight into synthetic Schiff bases revealing antiproliferative activities in vitro

Bioorganic and Medicinal Chemistry

Volumn 21, Issue 13, 2013, Pages 3648-3666

  Sztanke, Krzysztof ^a   Maziarka, Agata ^a   Osinka, Anna ^a   Sztanke, Małgorzata ^a  

^a MEDICAL UNIVERSITY OF LUBLIN   (Poland)

Author keywords

Aldimine type; Applications; Azomethines; Biological activities; Human tumour cells; Ketimine type; Lead structures; SAR; Schiff bases; Synthesis; The in vitro cytotoxicities

Indexed keywords

1H BENZIMIDAZOLE; 1H PYRAZOLE; 2 [[[2 (1H PYRAZOL 1 YL)ETHYL]IMINO]METHYL]PHENOL; 2,3 BUTANEDIONE; 2,4 DICHLORO 6 [[[2 (1H PYRAZOL 1 YL)ETHYL]IMINO]METHYL]PHENOL; 4 [(PYRIDINE 2 YLAMINO)SULFONYL]BENZENE; 4 AMINO 5 PHENYL 2H 1,2,4 TRIAZOLE 3(4H) THIONE; 4 METHYLANILINE; 5 AMINO 6 CYANO 7 (4 METHOXYPHENYL) 7H 2 (4 SULFAMOYLPHENYLAMINO)PYRANO[2,3 D]THIAZOLE; ALOIN; ANILINE DERIVATIVE; BENZENE DERIVATIVE; BENZIMIDAZOLE; BENZO[D]ISOTHIAZOLE; GOSSYPOL; N (2 FURFURYLIDENE) 4 TOLUIDINE; N (4 DIMETHYLAMINOBENZYLIDENE) 4 TOLUIDINE; N BENZYLIDENEANILINE DERIVATIVE; PHENOL DERIVATIVE; PYRAZOLE DERIVATIVE; PYRIDINE DERIVATIVE; QUINOLINE; S METHYLDITHIOCARBAZATE; S PHENYLDITHIOCARBAZATE; SCHIFF BASE; THIAZOLE DERIVATIVE; THIOL DERIVATIVE; THIOPHENE; THIOSEMICARBAZIDE; UNCLASSIFIED DRUG; UNINDEXED DRUG; ANTINEOPLASTIC AGENT; AZO COMPOUND; AZOMETHINE; THIOSEMICARBAZONE DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; BIOLOGICAL ACTIVITY; CANCER CELL CULTURE; CANCER INHIBITION; CARCINOMA CELL; DRUG CYTOTOXICITY; DRUG MECHANISM; HUMAN; IC 50; IN VITRO STUDY; LEUKEMIA CELL; NONHUMAN; PHARMACOPHORE; QUANTITATIVE STRUCTURE ACTIVITY RELATION; REVIEW; ANIMAL; CELL PROLIFERATION; CHEMISTRY; DRUG DEVELOPMENT; DRUG EFFECTS; NEOPLASMS;

ANIMALS; ANTINEOPLASTIC AGENTS; AZO COMPOUNDS; CELL PROLIFERATION; DRUG DISCOVERY; HUMANS; NEOPLASMS; SCHIFF BASES; THIOSEMICARBAZONES;

EID: 84878531996     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2013.04.037     Document Type: Review

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