Antiproliferative effects of some N-benzylideneanilines

Cell Biochemistry and Function

Volumn 26, Issue 1, 2008, Pages 102-106

  Özkay, Yusuf ^a   Incesu, Zerrin ^a   Işikdaǧ, Ilhan ^a   Yeşilkaya, Mehmet ^a  

^a ANADOLU UNIVERSITY   (Turkey)

Author keywords

Cytotoxic; N benzylideneaniline; Proliferation; Schiff bases; Small lung (A549) and cervical (HeLa) cancer cell lines

Indexed keywords

ANILINE DERIVATIVE; BENZYLIDENEANILINE; SCHIFF BASE; UNCLASSIFIED DRUG;

ARTICLE; BIOASSAY; CANCER CELL CULTURE; CELL PROLIFERATION; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFECT; FEMALE; HELA CELL; HUMAN; HUMAN CELL; INFRARED SPECTROSCOPY; LUNG SMALL CELL CANCER; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; UTERINE CERVIX CANCER;

ANILINE COMPOUNDS; ANTINEOPLASTIC AGENTS; BENZYLIDENE COMPOUNDS; CELL LINE, TUMOR; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; GROWTH INHIBITORS; HELA CELLS; HUMANS; SCHIFF BASES; TIME FACTORS;

EID: 38549109741     PISSN: 02636484     EISSN: 10990844     Source Type: Journal    
DOI: 10.1002/cbf.1406     Document Type: Article

References (21)

1. Popiołkiewicz J, Polkowski K, Skierski JS, Mazurek AP. In vitro toxicity evaluation in the development of new anticancer drugs-genistein glycosides. Cancer Lett 2005; 229: 67-75.
2. Karatepe M, Karatas F. Antioxidant, pro-oxidant effect of the thiosemicarbazone derivative Schiff base (4-(1-phenylmethylcyclobutane-3-yl)-2- (2-hydroxybenzylidenehydrazino) thiazole) and its metal complexes on rats. Cell Biochem Funct 2006; 24: 547-554.
3. Wang PH, Keck JG, Lien EJ, Lai MMC. Design, synthesis, testing and quantitative structure-activity relationship analysis of substituted salicylaldehyde schiff bases of 1-amino-3-hydroxyquanidine tosylate as new antiviral agents against coronavirus. J Med Chem 1990; 33: 608-614.
4. Pattanashetti PP, Tikare RK, Dambal DB, Badami BV, Puranik GS. Syntheses and biological activities of 3-[4-(alkoxycarbonyl)phenyl]sydnones and their derivatives. Arch Pharm 1984; 317: 59-63.
5. Iqbal MS, Bukhari IH, Arif M. Preparation, characterization and biological evaluation of copper(II) and zinc(II) complexes with Schiff bases derived from amoxicillin and cephalexin. Appl Organometal Chem 2005; 19: 864-869.
6. Tai AW, Lien EJ, Lai MMC, Khwaja TA. Novel N-hydroxyguanidine derivatives as anticancer and antiviral agents. J Med Chem 1984; 27: 236-238.
7. Tang A, Lien EJ, Lai MMC. Optimization of the Schiff bases of N-hydroxy-N′-aminoguanidine as anticancer and antiviral agents. J Med Chem 1985; 28: 1103-1106.
8. Jarrahpour AA, Zarei M. Synthesis of novel azo Schiff base bis[5-(4-methoxyphenylazo)-2-hydroxy-3-methoxy benzaldehyde]-1,2-phenylene dimine. Molbank 2004; 9: M377.
9. Oner H, Karatepe M, Karatas F, Oner J, Yilmaz I, Cukurovali Alaaddin. Effects on rat testes of the thiosemicarbazone derivative Schiff base (4-(1 phenylmethylcyclobutane-3-yl)- 2-(2-hydroxybenzylidenehydrazino)thiazole) and its cadmium(II) complex. Cell Biochem Funct 2005; 23: 427-433.
10. Al-Allaf TAK, Al-Sham'a MA, Rashan LJ. Diorganotin(IV) complexes of some Schiff bases with a potential biological activity. Appl Organometal Chem 1996; 10: 545-548.
11. Hodnett EM, Dunn WJ. Structure-antitumor activity correlation of some Schiff bases. J Med Chem 1970; 13: 768-770.
12. Hodnett EM, Money PD. Antitumor activity of some schiff bases. J Med Chem 1970; 13: 786.
13. Desai SB, Desai PB, Desai KR. Synthesis of some schiff bases, thiazolidinones and azetidinones derived from 2,6-diaminobenzo[1,2-d: 4,5-d ′]bisthiazole and their anticancer activities. Hetrocycl Commun 2001; 7: 83-90.
14. Pathak P, Jolly VS, Sharma KP. Synthesis and biological activities of some new substituted arylazo Schiff bases. Oriental J Chem 2000; 16: 161-162.
15. Zeytinoglu H, Incesu Z, Baser KHC. Inhibition of DNA synthesis by carvacrol in mouse myoblast cells bearing a human N-RAS oncogene. Phytomedicine 2003; 10: 292-299.
16. Chen CF, Hwang CM, Wu CH, Chen CS, Chen KY. Evalation of a rapid rapid tetrazolium-based colorimetric assay for selecting anticancer drugs. Chinese Med J Free China Ed 1990; 46: 7-16.
17. Demirayak S, Beis R, Karaburun AC, Kayagil I, Incesu Z, Ucucu U. Synthesis and cytotoxic and analgesic activities of some 1,5-diaryl-3- ethoxycarbonylpyrrole derivatives. J Enzyme Inhib Med Chem 2006; 1: 113-118.
18. Srzic D, Cevizoyic N, Meic Z. Mass spectrometric investigation of benzylideneaniline. Org Mass Spectrom 1987; 22: 400-405.
19. Tabei K, Saitou E. The nuclear magnetic resonance and infrared spectra of aromatic azomethines. Bull Chem Soc Jpn 1969; 42: 1440-1443.
20. 1H NMR spectra of substituted N-benzylideneanilines and Hammett correlations. Magn Reson Chem 1985; 23: 809-813.
21. 1H NMR spectra of 4-and 4′-substituted trans benzylideneanilines in acidic solution. Magn Reson Chem 1985; 23: 908-915.