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Volumn 70, Issue 3, 1998, Pages 922-931

Cloning and functional characterization of a σ receptor from rat brain

Author keywords

Brain; Functional expression; Primary structure; Steroids; ligands; receptor

Indexed keywords

1,3 BIS(2 METHYLPHENYL)GUANIDINE; CLORGYLINE; COMPLEMENTARY DNA; ESTRADIOL; HALOPERIDOL; LIGAND; MESSENGER RNA; OPIATE RECEPTOR; PENTAZOCINE; PENTOXYVERINE; POLYADENYLATED RNA; PRECLAMOL; PRENYLAMINE; PROGESTERONE; RECEPTOR SUBTYPE; TESTOSTERONE;

EID: 0031892683     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1998.70030922.x     Document Type: Article
Times cited : (286)

References (44)
  • 1
    • 0025128965 scopus 로고
    • σ receptor blockade by BMY 14802 affects enkephalinergic and tachykinin cells differentially in the striatum of the rat
    • Angulo J. A., Cadet J. L., and McEwen B. S. (1990) σ receptor blockade by BMY 14802 affects enkephalinergic and tachykinin cells differentially in the striatum of the rat. Eur. J. Pharmacol. 175, 225-228.
    • (1990) Eur. J. Pharmacol. , vol.175 , pp. 225-228
    • Angulo, J.A.1    Cadet, J.L.2    McEwen, B.S.3
  • 2
    • 0027247938 scopus 로고
    • Evidence for in vivo interactions between neuropeptide Y-related peptides and a receptors in the mouse hippocampal formation
    • Bouchard P., Dumont Y., Fournier A., St.-Pierre S., and Quirion R. (1993) Evidence for in vivo interactions between neuropeptide Y-related peptides and a receptors in the mouse hippocampal formation. J. Neurosci. 13, 3926-3931.
    • (1993) J. Neurosci. , vol.13 , pp. 3926-3931
    • Bouchard, P.1    Dumont, Y.2    Fournier, A.3    St.-Pierre, S.4    Quirion, R.5
  • 3
    • 0030960790 scopus 로고    scopus 로고
    • Protein phosphorylation and calcium uptake into rat forebrain synaptosomes: Modulation by the σ ligand 1,3-ditolylguanidine
    • Brent P. J., Herd L., Saunders H., Sim A. T. R., and Dunkley P. R. (1997) Protein phosphorylation and calcium uptake into rat forebrain synaptosomes: modulation by the σ ligand 1,3-ditolylguanidine. J. Neurochem. 68, 2201-2211.
    • (1997) J. Neurochem. , vol.68 , pp. 2201-2211
    • Brent, P.J.1    Herd, L.2    Saunders, H.3    Sim, A.T.R.4    Dunkley, P.R.5
  • 4
    • 0342683808 scopus 로고    scopus 로고
    • Dextromethorphan protects against cerebral injury following transient, but not permanent, focal ischemia in rats
    • Britton P., Lu X. C. M., Laskosky M. S., and Tortella F. C. (1997) Dextromethorphan protects against cerebral injury following transient, but not permanent, focal ischemia in rats. Life Sci. 60, 1729-1740.
    • (1997) Life Sci. , vol.60 , pp. 1729-1740
    • Britton, P.1    Lu, X.C.M.2    Laskosky, M.S.3    Tortella, F.C.4
  • 5
    • 0028149215 scopus 로고
    • Selective antagonism of opioid analgesia by a sigma system
    • Chien C. C. and Pasternak G. W. (1994) Selective antagonism of opioid analgesia by a sigma system. J. Pharmacol. Exp. Ther. 271, 1583-1590.
    • (1994) J. Pharmacol. Exp. Ther. , vol.271 , pp. 1583-1590
    • Chien, C.C.1    Pasternak, G.W.2
  • 6
    • 0028930208 scopus 로고
    • Sigma antagonists potentiate opioid analgesia in rats
    • Chien C. C. and Pasternak G. W. (1995) Sigma antagonists potentiate opioid analgesia in rats, Neurosci. Lett. 190, 137-139.
    • (1995) Neurosci. Lett. , vol.190 , pp. 137-139
    • Chien, C.C.1    Pasternak, G.W.2
  • 8
    • 0028967328 scopus 로고
    • σ receptor-mediated neuroprotection against glutamate toxicity in primary rat neuronal cultures
    • De Coster M. A., Klette K. L., Knight E. S., and Tortella F. C. (1995) σ receptor-mediated neuroprotection against glutamate toxicity in primary rat neuronal cultures. Brain Res. 671, 45-53.
    • (1995) Brain Res. , vol.671 , pp. 45-53
    • De Coster, M.A.1    Klette, K.L.2    Knight, E.S.3    Tortella, F.C.4
  • 10
    • 0024822479 scopus 로고
    • Cerebral metabolic effects of σ ligands in the rat
    • Della-Puppa A. and London E. D. (1989) Cerebral metabolic effects of σ ligands in the rat. Brain Res. 505, 283-290.
    • (1989) Brain Res. , vol.505 , pp. 283-290
    • Della-Puppa, A.1    London, E.D.2
  • 11
    • 0021691817 scopus 로고
    • Analysis of membrane and surface protein sequences with the hydrophobic moment plot
    • Eisenberg D., Schwarz E., Komaromy M., and Wall R. (1984) Analysis of membrane and surface protein sequences with the hydrophobic moment plot. J. Mol. Biol. 179, 125-142.
    • (1984) J. Mol. Biol. , vol.179 , pp. 125-142
    • Eisenberg, D.1    Schwarz, E.2    Komaromy, M.3    Wall, R.4
  • 13
    • 0027378410 scopus 로고
    • Characterization of a (+)-azidophenazocine-sensitive sigma receptor on splenic lymphocytes
    • Garza H. H. Jr., Mayo S., Bowen W. D., De Costa B. R., and Carr D. J. J. (1993) Characterization of a (+)-azidophenazocine-sensitive sigma receptor on splenic lymphocytes. J. Immunol. 151, 4672-4680.
    • (1993) J. Immunol. , vol.151 , pp. 4672-4680
    • Garza Jr., H.H.1    Mayo, S.2    Bowen, W.D.3    De Costa, B.R.4    Carr, D.J.J.5
  • 16
    • 0025180755 scopus 로고
    • A sigma-like binding site in rat pheochromocytoma (PC12) cells: Decreased affinity for (+)-benzomorphans and lower molecular weight suggest a different sigma receptor form from that of guinea pig brain
    • Hellewell S. B. and Bowen W. D. (1990) A sigma-like binding site in rat pheochromocytoma (PC12) cells: decreased affinity for (+)-benzomorphans and lower molecular weight suggest a different sigma receptor form from that of guinea pig brain. Brain Res. 527, 244-253.
    • (1990) Brain Res. , vol.527 , pp. 244-253
    • Hellewell, S.B.1    Bowen, W.D.2
  • 17
    • 0025009458 scopus 로고
    • Sigma binding sites in the brain: An emerging concept of multiple sites and their relevance for psychiatric disorders
    • Itzhak Y. and Stein I. (1990) Sigma binding sites in the brain: an emerging concept of multiple sites and their relevance for psychiatric disorders. Life Sci. 47, 1073-1081.
    • (1990) Life Sci. , vol.47 , pp. 1073-1081
    • Itzhak, Y.1    Stein, I.2
  • 21
    • 0025183196 scopus 로고
    • Sigma receptor "antagonist" BMY 14802 increases neurotensin concentrations in the rat nucleus accumbens and caudate
    • Levant B. and Nemeroff C. B. (1990) Sigma receptor "antagonist" BMY 14802 increases neurotensin concentrations in the rat nucleus accumbens and caudate. J. Pharmacol. Exp. Ther. 254, 330-335.
    • (1990) J. Pharmacol. Exp. Ther. , vol.254 , pp. 330-335
    • Levant, B.1    Nemeroff, C.B.2
  • 22
    • 0017064976 scopus 로고
    • The effects of morphine and nalorphine-like drugs in the nondependent and morphine-dependent chronic spinal dog
    • Martin W. R., Eades C. G., Thompson J. A., Huppler R. E., and Gilbert P. E. (1976) The effects of morphine and nalorphine-like drugs in the nondependent and morphine-dependent chronic spinal dog. J. Pharmacol. Exp. Ther. 197, 517-532.
    • (1976) J. Pharmacol. Exp. Ther. , vol.197 , pp. 517-532
    • Martin, W.R.1    Eades, C.G.2    Thompson, J.A.3    Huppler, R.E.4    Gilbert, P.E.5
  • 23
    • 0025738352 scopus 로고
    • 3H]SKF-10,047 binding sites (sigma sites) from rat liver membranes
    • 3H]SKF-10,047 binding sites (sigma sites) from rat liver membranes. J. Pharmacol. Exp. Ther. 257, 547-554.
    • (1991) J. Pharmacol. Exp. Ther. , vol.257 , pp. 547-554
    • McCann, D.J.1    Su, T.P.2
  • 24
    • 0027367309 scopus 로고
    • Identification of a 27-kDa high affinity phenylalkylamine-binding polypeptide as the σ1 binding site by photoaffinity labeling and ligand-directed antibodies
    • Moebius F. F., Burrows G. G., Hanner M., Schmid E., Striessnig J., and Glossman H. (1993a) Identification of a 27-kDa high affinity phenylalkylamine-binding polypeptide as the σ1 binding site by photoaffinity labeling and ligand-directed antibodies. Mol. Pharmacol. 44, 966-971.
    • (1993) Mol. Pharmacol. , vol.44 , pp. 966-971
    • Moebius, F.F.1    Burrows, G.G.2    Hanner, M.3    Schmid, E.4    Striessnig, J.5    Glossman, H.6
  • 25
    • 0027463541 scopus 로고
    • Biochemical characterization of a 22-kDa high affinity antiischemic drug-binding polypeptide in the endoplasmic reticulum of guinea pig liver: Potential common target for antiischemic drug action
    • Moebius F. F., Burrows G. G., Striessnig J., and Glossman H. (1993b) Biochemical characterization of a 22-kDa high affinity antiischemic drug-binding polypeptide in the endoplasmic reticulum of guinea pig liver: potential common target for antiischemic drug action. Mol. Pharmacol. 43, 139-148.
    • (1993) Mol. Pharmacol. , vol.43 , pp. 139-148
    • Moebius, F.F.1    Burrows, G.G.2    Striessnig, J.3    Glossman, H.4
  • 26
    • 0030949390 scopus 로고    scopus 로고
    • The mysteries of sigma receptors: New family members reveal a role in cholesterol synthesis
    • Moebius F. F., Striessnig J., and Glossmann H. (1997) The mysteries of sigma receptors: new family members reveal a role in cholesterol synthesis. Trends Pharmacol. Sci. 18, 67-70.
    • (1997) Trends Pharmacol. Sci. , vol.18 , pp. 67-70
    • Moebius, F.F.1    Striessnig, J.2    Glossmann, H.3
  • 27
    • 0025228974 scopus 로고
    • N-Methyl-D-aspartate induced neuronal activation is selectively modulated by a receptors
    • Monnet F. P., Debonnel G., Junien J. L., and De Montigny C. (1990) N-Methyl-D-aspartate induced neuronal activation is selectively modulated by a receptors. Eur. J. Pharmacol. 179, 441-445.
    • (1990) Eur. J. Pharmacol. , vol.179 , pp. 441-445
    • Monnet, F.P.1    Debonnel, G.2    Junien, J.L.3    De Montigny, C.4
  • 29
    • 0023775221 scopus 로고
    • High affinity dextromethorphan binding sites in the guinea pig brain: Further characterization and allosteric interactions
    • Musacchio J. M., Klein M., and Santiago L. J. (1988) High affinity dextromethorphan binding sites in the guinea pig brain: further characterization and allosteric interactions. J. Pharmacol. Exp. Ther. 247, 424-431.
    • (1988) J. Pharmacol. Exp. Ther. , vol.247 , pp. 424-431
    • Musacchio, J.M.1    Klein, M.2    Santiago, L.J.3
  • 33
    • 0028985144 scopus 로고
    • Cocaine-sensitive σ-receptor and its interaction with steroid hormones in the human placental syncytiotrophoblast and in choriocarcinoma cells
    • Ramamoorthy J. D., Ramamoorthy S., Mahesh V. B., Leibach F. H., and Ganapathy V. (1995) Cocaine-sensitive σ-receptor and its interaction with steroid hormones in the human placental syncytiotrophoblast and in choriocarcinoma cells. Endocrinology 136, 924-932.
    • (1995) Endocrinology , vol.136 , pp. 924-932
    • Ramamoorthy, J.D.1    Ramamoorthy, S.2    Mahesh, V.B.3    Leibach, F.H.4    Ganapathy, V.5
  • 34
    • 0025131242 scopus 로고
    • Neuropeptide Y and JO 1784, a selective sigma ligand, alter intestinal ion transport through a common, haloperidol-sensitive site
    • Riviere P. J. M., Pascaud X., Junien J. L., and Porreca F. (1990) Neuropeptide Y and JO 1784, a selective sigma ligand, alter intestinal ion transport through a common, haloperidol-sensitive site. Eur. J. Pharmacol. 187, 557-559.
    • (1990) Eur. J. Pharmacol. , vol.187 , pp. 557-559
    • Riviere, P.J.M.1    Pascaud, X.2    Junien, J.L.3    Porreca, F.4
  • 36
    • 0025924672 scopus 로고
    • 3H] 1,3-di(2-tolyl)-guanidine of two high affinity binding sites in guinea pig brain: Evidence for allosteric regulation by calcium channel antagonists and pseudoallosteric modulation by sigma ligands
    • 3H] 1,3-di(2-tolyl)-guanidine of two high affinity binding sites in guinea pig brain: evidence for allosteric regulation by calcium channel antagonists and pseudoallosteric modulation by sigma ligands. Mol. Pharmacol. 39, 222-232.
    • (1991) Mol. Pharmacol. , vol.39 , pp. 222-232
    • Rothman, R.B.1    Reid, A.2    Mahboubi, A.3    Kim, C.H.4    De Costa, B.R.5    Jacobson, A.E.6
  • 37
    • 9544223310 scopus 로고    scopus 로고
    • Emopamil-binding protein, a mammalian protein that binds a series of structurally diverse neuroprotective agents, exhibits Δ8-Δ7 sterol isomerase activity in yeast
    • Silve S., Dupuy P. H., Labit-Lebouteiller C., Kaghad M., Chalon P., Rahier A., Taton M., Lupker J., Shire D., and Loison G. (1996) Emopamil-binding protein, a mammalian protein that binds a series of structurally diverse neuroprotective agents, exhibits Δ8-Δ7 sterol isomerase activity in yeast. J. Biol. Chem. 271, 22434-22440.
    • (1996) J. Biol. Chem. , vol.271 , pp. 22434-22440
    • Silve, S.1    Dupuy, P.H.2    Labit-Lebouteiller, C.3    Kaghad, M.4    Chalon, P.5    Rahier, A.6    Taton, M.7    Lupker, J.8    Shire, D.9    Loison, G.10
  • 38
    • 0025881278 scopus 로고
    • σ receptors: Putative links between nervous, endocrine and immune systems
    • Su T. P. (1991) σ receptors: putative links between nervous, endocrine and immune systems. Eur. J. Biochem. 200, 633-642.
    • (1991) Eur. J. Biochem. , vol.200 , pp. 633-642
    • Su, T.P.1
  • 39
    • 0024281403 scopus 로고
    • Steroid binding at σ receptor suggests a link between endocrine, nervous, and immune systems
    • Su T. P., London E. D., and Jaffe J. H. (1988) Steroid binding at σ receptor suggests a link between endocrine, nervous, and immune systems. Science 240, 219-221.
    • (1988) Science , vol.240 , pp. 219-221
    • Su, T.P.1    London, E.D.2    Jaffe, J.H.3
  • 40
    • 0028795145 scopus 로고
    • Sigma-1 and sigma-2 receptors are expressed in a wide variety of human and rodent tumor cell lines
    • Vilner B. J., John C. S., and Bowen W. D. (1995) Sigma-1 and sigma-2 receptors are expressed in a wide variety of human and rodent tumor cell lines. Cancer Res. 55, 408-413.
    • (1995) Cancer Res. , vol.55 , pp. 408-413
    • Vilner, B.J.1    John, C.S.2    Bowen, W.D.3
  • 41
    • 0023088232 scopus 로고
    • Amplification, storage, and replication of libraries
    • Vogeli G. and Kaytes P. S. (1987) Amplification, storage, and replication of libraries. Methods Enzymol. 152, 407-415.
    • (1987) Methods Enzymol. , vol.152 , pp. 407-415
    • Vogeli, G.1    Kaytes, P.S.2
  • 42
    • 0023877507 scopus 로고
    • Electrophysiological effects of BMY 14802, a new potential antipsychotic drug, on midbrain dopamine neurons in the rat: Acute and chronic studies
    • Wachtel S. R. and White F. J. (1988) Electrophysiological effects of BMY 14802, a new potential antipsychotic drug, on midbrain dopamine neurons in the rat: acute and chronic studies. J. Pharmacol. Exp. Ther. 244, 410-416.
    • (1988) J. Pharmacol. Exp. Ther. , vol.244 , pp. 410-416
    • Wachtel, S.R.1    White, F.J.2
  • 44
    • 0028140473 scopus 로고
    • Pharmacotherapy of cocaine abuse: Preclinical development
    • Witkin J. M. (1994) Pharmacotherapy of cocaine abuse: preclinical development. Neurosci. Behav. Rev. 18, 121-142.
    • (1994) Neurosci. Behav. Rev. , vol.18 , pp. 121-142
    • Witkin, J.M.1


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